• The Bulletin of The Korean Astronomical Society
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• v.44 no.2
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• pp.78.1-78.1
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• 2019

There are a huge number of faint objects that have not been observed due to the lack of large and deep surveys. In this study, we demonstrate that a deep learning approach can produce a better quality deep image from a single pass imaging so that could be an alternative of conventional image stacking technique or the expensive large and deep surveys. Using data from the Sloan Digital Sky Survey (SDSS) stripe 82 which provide repeatedly scanned imaging data, a training data set is constructed: g-, r-, and i-band images of single pass data as an input and r-band co-added image as a target. Out of 151 SDSS fields that have been repeatedly scanned 34 times, 120 fields were used for training and 31 fields for validation. The size of a frame selected for the training is 1k by 1k pixel scale. To avoid possible problems caused by the small number of training sets, frames are randomly selected within that field each iteration of training. Every 5000 iterations of training, the performance were evaluated with RMSE, peak signal-to-noise ratio which is given on logarithmic scale, structural symmetry index (SSIM) and difference in SSIM. We continued the training until a GAN model with the best performance is found. We apply the best GAN-model to NGC0941 located in SDSS stripe 82. By comparing the radial surface brightness and photometry error of images, we found the possibility that this technique could generate a deep image with statistics close to the stacked image from a single-pass image.

• Molecules and Cells
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• v.25 no.1
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• pp.55-63
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• 2008

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the selective death of motor neurons. Mutations in the SOD1 gene are responsible for a familial form of ALS (FALS). Although many studies suggest that mutant SOD1 proteins are cytotoxic, the mechanism is not fully understood. To investigate the role of mutant SOD1 in FALS, human SOD1 genes were fused with a PEP-1 peptide in a bacterial expression vector to produce in-frame PEP-1-SOD fusion proteins (wild type and mutants). The expressed and purified PEP-1-SOD fusion proteins were efficiently transduced into neuronal cells. Neurones harboring the A4V, G93A, G85R, and D90A mutants of PEP-1-SOD were more vulnerable to oxidative stress induced by paraquat than those harboring wild-type proteins. Moreover, neurones harboring the mutant SOD proteins had lower heat shock protein (Hsp) expression levels than those harboring wild-type SOD. The effects of the transduced SOD1 fusion proteins may provide an explanation for the association of SOD1 with FALS, and Hsps could be candidate agents for the treatment of ALS.

• Korean Journal of Microbiology
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• v.50 no.4
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• pp.351-359
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• 2014

A beverage was produced by the fermentation of mixed extracts from the various fruits, vegetables, algae, and medical herbs. The physicochemical properties of the fermented beverage of plant extracts (FBPE) and microbial diversity were analyzed in cultures enriched from FBPE using 16S and 26S rRNA gene sequence analyses. The pH, acidity, $^{\circ}brix$, reducing sugar, and alcohol contents of the FBPE were determined to be the 3.48, 1.68%, 70.0, 1,026 g/L, and 3.5%, respectively. The most abundant free sugar and organic acid in the FBPE were glucose (567.83 g/L) and tartaric acid (93.68 mg/L), respectively. Lactobacillus homohiochii was the predominant species in all enriched culture samples: 100% of the species in 0B (0% sugar) and 40B (40% sugar) libraries and 95.6% of 20B library (20% sugar). Lactobacillus fructivorans was detected in the 20B library. The predominant species in the samples of enrichment cultures collected from FBPE with three different sugar concentrations were: Candida zeylanoides (45.2%) in the 0Y library (0% sugar), Candida lactis-condensi (35.7%) and C. zeylanoides (35.7%) in the 20Y library (20% sugar), and C. lactis-condensi (38.1%) in the 40Y library (40% sugar). This result may provide a useful frame of reference for further analyses of microbial population dynamics in FBPE.

• Korean Journal of Microbiology
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• v.49 no.1
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• pp.8-16
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• 2013

A GAL4 type transcription factor gene (formally annotated as AN3912) locating downstream of sndA (AN3911) was characterized. The putative transcription factor carries both Zn(II)2Cys6 binuclear cluster DNA-binding domain and transcription activator domain. The gene named gtfA (gal4 type transcription factor) had an open reading frame which consisted of 762 amino acids and was disrupted by three introns. The deletion mutant produced reduced amount of conidia but increased amount of fruiting bodies, suggesting that the GtfA make function in decision of asexual preferential to sexual development. The forced over expression of gtfA caused the retardation of fruiting body formation on high glucose concentration. The transcript level of gtfA was kept constant through the life cycle except late vegetative stage and early sexual development stage during which slight increase was found. The expression of gtfA was not significantly affected by sexual or asexual development regulators, such as VeA, NsdD or FluG, FadA, and SfaD. The GtfA repressed the nsdC transcription, which suggested that GftA control sexual development negatively via negative regulation of nsdC expression.

• The Korean Society of Law and Medicine
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• v.9 no.1
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• pp.413-459
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• 2008

The Law has intervened to define rare circumstances in which a person should choose continuing life in United States. On the one hand, the law has traditionally acted to preservelife and to respect the sanctity of life. On the other hand, one's control over one's own body, and the right to determine what kind of medical care one will receive, is equally well respected and historically grounded. The competent patients have the right to forgo life-sustaining treatment, courts in United States have left many unanswered questions about the nature of that right. The right to choose to forgo life-sustaining treatment is a manifestation of a patient's autonomy interest. In United States, The Karen Quilan case gave rise to legislative activity in the host of state capitals, and several states had adopted statutes that formally recognized some forms of written directives describing some circumstances in which certain kinds of medical care could be terminated. These statues were sometimes dominated 'living will' acts, sometimes 'right to die' acts and ocasionally 'natural death' acts. Today virtually every state has produced a living will statue. In Korea, courts do not permit a terminally ill person to withhold or withdraw life-sustaining treatment. Living wills apply in case of terminal illness owing to a defect in legislation. Now In Korea, these lively dispute of legal policy on the preconditions and concrete procedure of living will act and natural death act. Through the legislation of living will act and natural death act, we should prepare some circumstances to respect patient's autonomy on the right to die. We should frame the cultural standard to make a decision of forgoing life-sustainin1g treatment under the discreet procedure.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.5
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• pp.606-612
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• 2012

Insulin-like growth factor-binding protein-5 (IGFBP-5) is one of the six members of IGFBP family, important for cell growth, apoptosis and other IGF-stimulated signaling pathways. In order to explore the significance of IGFBP-5 in cells of the Inner Mongolian Cashmere goat (Capra hircus), IGFBP-5 gene complementary DNA (cDNA) was amplified by reverse transcription polymerase chain reaction (RT-PCR) from the animal's fetal fibroblasts and tissue-specific expression analysis was performed by semi-quantitative RT-PCR. The gene is 816 base pairs (bp) in length and includes the complete open reading frame, encoding 271 amino acids (GenBank accession number JF720883). The full cDNA nucleotide sequence has a 99% identity with sheep, 98% with cattle and 95% with human. The amino acids sequence shares identity with 99%, 99% and 99%, respectively. The bioinformatics analysis showed that IGFBP-5 has an insulin growth factor-binding protein homologues (IB) domain and a thyroglobulin type-1 (TY) domain, four protein kinase C phosphorylation sites, five casein kinase II phosphorylation sites, three prenyl group binding sites (CaaX box). The IGFBP-5 gene was expressed in all the tested tissues including testis, brain, liver, lung, mammary gland, spleen, and kidney, suggesting that IGFBP-5 plays an important role in goat cells.

• Journal of Distribution Science
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• v.15 no.7
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• pp.73-83
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• 2017

Purpose - The purpose of this paper is to explore the CSR activities of small enterprises in hospitality and tourism industry in South Korea. Since previous research on CSR activities has considerably focused on large enterprises whereas small enterprises have relatively less attention, this study aims to explore the characteristics of small enterprises in hospitality and tourism industry and their CSR activities. Research design, data, and methodology - The population of interest for this study was social enterprises registered in Korea Social Enterprise Promotion Agency (2016), and it was used to verify the social enterprises which has a certification for social enterprises. From 1672 companies in total, the sampling frame was a database with 117 companies in hospitality and tourism industry. This study investigates social enterprises' CSR activities on the company's official websites (e.g., company reports, magazines, the news articles, and interviews). The websites of the selected enterprises in hospitality and tourism industry were analyzed for examining CSR activities by the quantitative content analysis. All of the CSR activities in small social enterprises were classified into six dimensions based on the stakeholder theory. Results - The findings of this study provide the characteristics of the 117 small social enterprises and their specific CSR initiatives. A total of eight main business lines were identified: 1) fair travel, 2) leisure/sports, 3) accommodation/camping, 4) medical tourism, 5) exhibitions/art events/cultural events, 6) leisure activities for vulnerable social groups, 7) Korean traditional culture, and 8) ecotourism/agricultural tourism. The CSR initiatives were classified into six dimensions: 1) environment, 2) employment, 3) multicultural families and vulnerable social groups, 4) local community, 5) economic prosperity, and 6) product. Conclusions - This study revealed the special CSR initiative examples of small enterprises in hospitality and tourism industry. Small social enterprises participate in CSR activities mainly related to their own business lines. Moreover, these enterprises are more closely embedded in their local community development, job creation and education for local residents and vulnerable social groups, and traditional heritage preservation. The findings of this study provide theoretical and practical implications and they can contribute to enrich CSR with literature for small enterprises in hospitality and tourism industry.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39B no.5
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• pp.260-270
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• 2014

In this paper, we first analyze the delay performance of Dynamic Space-time Subframe (DSTS)-based frame structure which has been proposed to support the real-time service as well as non real-time service, using Ad hoc Self-Organizing Time Division Multiple Access (ASO-TDMA) MAC protocol, especially when transmitting a MAC SDU with two or more MAC PDUs, in a multi-hop ad-hoc maritime communication network. We propose two key transmission schemes: contiguous DSTS reservation which guarantees the end-to-end delay for the multiple PDUs, and adaptive transmission probability control schemes to maximize the system throughput. Our simulation results show that the proposed schemes outperform the system throughput of the existing transmission schemes, while supporting the real-time requirement.

• Journal of Biosystems Engineering
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• v.27 no.2
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• pp.151-160
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• 2002

Cow image processing technique would be useful not only for recognizing an individual but also for establishing the image database and analyzing the shape of cows. A cow (Holstein) has usually the unique speckle pattern. In this study, the individual recognition of cow was carried out using the speckle pattern and the content-based image retrieval technique. Sixty cow images of 16 heads were captured under outdoor illumination, which were complicated images due to shadow, obstacles and walking posture of cow. Sixteen images were selected as the reference image for each cow and 44 query images were used for evaluating the efficiency of individual recognition by matching to each reference image. Run-lengths and positions of runs across speckle area were calculated from 40 horizontal line profiles for ROI (region of interest) in a cow body image after 3 passes of 5$\times$5 median filtering. A similarity measure for recognizing cow individuals was calculated using Euclidean distance of normalized G-frame histogram (GH). normalized speckle run-length (BRL), normalized x and y positions (BRX, BRY) of speckle runs. This study evaluated the efficiency of individual recognition of cow using Recall(Success rate) and AVRR(Average rank of relevant images). Success rate of individual recognition was 100% when GH, BRL, BRX and BRY were used as image query indices. It was concluded that the histogram as global property and the information of speckle runs as local properties were good image features for individual recognition and the developed system of individual recognition was reliable.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.29 no.10
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• pp.73-82
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• 2015

This paper proposes an ripple reduction algorithm and analyzes the effects of offset and scale errors generated by voltage sensor while measuring grid voltage in grid-tied single-phase inverters. Generally, the grid-connected inverter needs to detect the phase angle information by measuring grid voltage for synchronization, so that the single-phase inverter can be accurately driven based on estimated phase angle information. However, offset and scale errors are inevitably generated owing to the non-linear characteristics of voltage sensor and these errors affect that the phase angle includes 1st harmonic component under using SRF-PLL(Synchronous Reference Frame - Phase Locked Loop) system for detecting grid phase angle. Also, the performance of the overall system is degraded from the distorted phase angle including the specific harmonic component. As a result, in this paper, offset and scale error due to the voltage sensor in single-phase grid connected inverter under SRF-PLL is analyzed in detail and proportional resonant controller is used to reduce the ripples caused by the offset error. Especially, the integrator output of PI(Proportional Integral) controller in SRF-PLL is selected as an input signal of the proportional resonant controller. Simulation and experiment are performed to verify the effectiveness of the proposed algorithm.