• Title/Summary/Keyword: K-ToBI

Search Result 3,754, Processing Time 0.033 seconds

Antitumor Effect Of Bismuth-conjugated Anti-IL-2R Monoclonal Antibody(2E4) on a IL-2 Receptor Positive Tumor EL4J3.4

  • Kim, Sung-Hoon;Robert-W. Kozak;Chung, Kyeong-Soo;Ahn, Byung-Zun
    • Archives of Pharmacal Research
    • /
    • v.17 no.3
    • /
    • pp.194-198
    • /
    • 1994
  • The antitumor effects of the 2E4 and anti--Tac, monoclonal antibodies directed to Il-2 receptor (IL-2R) conjugated with .alpha.-particle emitting radionuclide bismuth-212., were compared. The $^{212}Bi-2E4$ demonstratedspecific cytotocicity to EL4J3, 4, a I$L-2R^+$ cell line, than to EL4J, a $IL-2R^-$ cell line in thymidine incorporation assy. TEX>$^{212}Bi-2E4$ exerted the maximal antitumor effect in that % T/C in C57BL/6 mice implanted with EL4J3.4 ascitic tumor was 331% at the concentration of $50{\;}{\mu}Ci$, while that of $^{212}Bi-anti-Tac$ was 258% at $100{\;}{\mu}Ci$.

  • PDF

Exact analysis of bi-directional functionally graded beams with arbitrary boundary conditions via the symplectic approach

  • Zhao, Li;Zhu, Jun;Wen, Xiao D.
    • Structural Engineering and Mechanics
    • /
    • v.59 no.1
    • /
    • pp.101-122
    • /
    • 2016
  • Elasticity solutions for bi-directional functionally graded beams subjected to arbitrary lateral loads are conducted, with emphasis on the end effects. The material is considered macroscopically isotropic, with Young's modulus varying exponentially in both axial and thickness directions, while Poisson's ratio remaining constant. In order to obtain an exact analysis of stress and displacement fields, the symplectic analysis based on Hamiltonian state space approach is employed. The capability of the symplectic framework for exact analysis of bi-directional functionally graded beams has been validated by comparing numerical results with corresponding ones in open literature. Numerical results are provided to demonstrate the influences of the material gradations on localized stress distributions. Thus, the material properties of the bi-directional functionally graded beam can be tailored for the potential practical purpose by choosing suitable graded indices.

How User's Participation in Feasibility Study Enhances Use of Business Intelligence Systems

  • Kim, Nam Gyu;Kim, Sung Kun
    • Journal of Information Technology Applications and Management
    • /
    • v.24 no.3
    • /
    • pp.1-21
    • /
    • 2017
  • Business Intelligence (BI) system is a strategic tool that presents an analytical perspective about business and external environments. Even though its strategic value was well known, users often avoid using it or adopt it ceremonially. In fact, over 50 per cent of BI projects worldwide are reported to end in failure. Such an unexpectedly lower success rate has been a key issue in BI studies. In order to enhance a proper use of information systems, MIS field provided a number of theoretical constructs. One example is Goodhue & Thompson's Task-Technology Fit (TTF). In addition, internalization, the degree to which people make their own effort to modify behavior, was recently suggested as another important determinant of use. Though in MIS community both TTF and internalization proved to be a key determinant of system use, there has been not much study aiming to discover antecedents influencing these constructs. In this study we assert that user participation should be highlighted in BI projects. Especially, we emphasize user participation at the phase of feasibility study that is mainly conducted to determine whether a BI system is essentially necessary and practicable. Our research model employs participative feasibility study as a major antecedent for TTF and internalization that consequently will lead to user satisfaction and actual use. This model was empirically tested on 121 BI system users. The result shows that user participation in feasibility study is positively associated with TTF and internalization, each being related to user satisfaction and system use. It implies that, if an organization has BI users get involved in strategic feasibility study phase, the BI system would turn out to fit users' tasks and, furthermore, users would put more efforts spontaneously in order to use it properly.

Gamma radiation shielding properties of poly (methyl methacrylate) / Bi2O3 composites

  • Cao, Da;Yang, Ge;Bourham, Mohamed;Moneghan, Dan
    • Nuclear Engineering and Technology
    • /
    • v.52 no.11
    • /
    • pp.2613-2619
    • /
    • 2020
  • This work investigated the gamma-ray shielding performance, and the physical and mechanical properties of poly (methyl methacrylate) (PMMA) composites embedded with 0-44.0 wt% bismuth trioxide (Bi2O3) fabricated by the fast ultraviolet (UV) curing method. The results showed that the addition of Bi2O3 had significantly improved the gamma shielding ability of PMMA composites. Mass attenuation coefficient and half-value layer were examined using five gamma sources (Cs-137, Ba-133, Cd-109, Co-57, and Co-60). The high loading of Bi2O3 in the PMMA samples improved the micro-hardness to nearly seven times that of the pure PMMA. With these enhancements, it was demonstrated that PMMA/Bi2O3 composites are promising gamma shielding materials. Furthermore, the fast UV curing exerts its great potential in significantly shortening the production cycle of shielding material to enable rapid manufacturing.

Ferroelectric properties of BET Thin Films for FRAM (FRAM 응용을 위한 BET 박막의 강유전 특성)

  • Kim, Kyoung-Tae;Kim, Tae-Hyung;Kim, Chang-Il
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2003.05c
    • /
    • pp.200-203
    • /
    • 2003
  • Ferroelectric europium-substitution $Bi_4Ti_3O_{12}$ thin films were fabricated by spin-coating onto a Pt/Ti/$SiO_2$/Si substrate. The $Bi_{3.25}Eu_{0.75}Ti_3O_{12}$ (BET) films have polycrystalline structure annealed at 700 C. We investigated that the influence of $Bi_4Ti_3O_{12}$ thin films by substituting for Bi ions with Bi ions using X-ray diffraction (XRD), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). From the XPS measurement, it was suggested that the stability of the metal-oxygen octahedral should be related to substitute for Bi ions with Eu ions at annealed $800^{\circ}C$. The BET thin films showed a large remanent polarization (2Pr) of $60.99C/cm^2$ at an applied voltage of 10 V. The BET thin films exhibited no significant degradation of switching charge at least up to $5{\times}10^9$ switching cycles at a frequency of 50 kHz.

  • PDF

Characteristics of Bi-2212 Superconductor Tube Depending on Heat-treatment Conditions (열처리 조건에 따른 Bi-2212 초전도 튜브의 특성)

  • 박용민;장건익
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.14 no.7
    • /
    • pp.606-610
    • /
    • 2001
  • Bi-2212 HTS tube was fabricated by centrifugal forming and partial melting processes. Bi-2212 bulk tube has been optimized to achieve smooth surface and uniform thickness. The slurry was prepared in the mixing ratio of 10:1 between Bi-2212 powder and binder and initially charged into the rotating mold under the speed of 300~450 rpm. Heat-treatment was performed at the temperature ranges of 860~89$0^{\circ}C$ in air for partial melting. the HTS tube fabricated by centrifugal forming process at 89$0^{\circ}C$ under the rotating speed of 450 rpm was highly densified and the plate-like grains with more than 20${\mu}{\textrm}{m}$ were well oriented along the rotating axis. The measured Tc and J$_{c}$ at 10K on specimen heat treated at 89$0^{\circ}C$ was around 85 K and 1,200 A/$\textrm{cm}^2$ respectively.y.

  • PDF

Comparison between BSCCO Thin Films Fabricated by Co-Deposition and Layer-by-Layer Deposition

  • Lee, Hee-Kab;Park, Yong-Pil;Lee, Joon-Ung
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2000.07a
    • /
    • pp.230-234
    • /
    • 2000
  • Bi$_2$Sr$_2$Ca$_{n}$Cu$_{n+1}$ O$_{y}$(n$\geq$0; BSCCO)thin film is fabricated via two different processes using an ion beam sputtering method i.e. co-deposition and layer-by-layer deposition. A single phase of Bi2212 can be fabricated via the co-deposition process. While it cannot be obtained by the layer-by-layer process. Ultra-law growth rate in our ion beam sputtering system brings out the difference in Bi element adsorption between the two processes and results in only 30% adsorption against total incident Bi amount by layer-by-layer deposition, in contrast to enough Bi adsorption by co-deposition.on.n.

  • PDF

Superconducting Properties of Ge Substitution for the Bi Site in the 2212 Phase of Bi-Sr-Ca-Cu-O Superconductors (Bi계 산화물 초전도체 2212상에 있어서 Bi 자리에 Ge 치환에 따른 초전도 특성)

  • 신재수;이민수;최봉수;송승용;송기영
    • Journal of the Korean Ceramic Society
    • /
    • v.37 no.8
    • /
    • pp.787-791
    • /
    • 2000
  • Samples with the nominal composition, Bi2-xGexSr2CaCu2O8+$\delta$ (x=0, 0.1, 0.2, 0.3, 0.4, 0.5) were prepared by the solid-state reaction method. We have studied the effect of substitution Ge for Bi and investigated the superconducting properties by changing oxygen content with Ge substitution. It was found that temperature difference, ΔK, between TCon and TCzero was considerably smaller in the samples prepared by the intermediate pressing method than that in the samples by the solid-state reaction method. We found the solubility limit of Ge to the 80 K single phase was around x=0.3. Within the solubility limit, lattice constant c decreased with the increase of x. In the region of the 80K single phase, the onset critical temperature TCon increased and excess oxygen content decreased with increase of x.

  • PDF

Study on the deposition Characteristics of Bi Thin Film (Bi 박막의 성막 특성에 관한 연구)

  • Yang, Dong-Bok;Park, Yong-Pil;Lee, Hee-Kab
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2003.05d
    • /
    • pp.61-64
    • /
    • 2003
  • This paper presents Bi thin films have been fabricated by atomic layer-by-layer deposition and co-deposition at an IBS method. The growth rates of the films was set in the region from 0.17 to 0.27 nm/min. Mg(100) was used as a substrate. In order to appreciate stable existing region of Bi 2212 phase with temperature and ozone pressure, the substrate temperature was varied between 655 and $820^{\circ}C$ and the highly condensed ozone gas pressure$(PO_3)$ in vacuum chamber was varied between $2.0{\times}10^{-6}$ and $2.3{\times}10^{-5}$ Torr. Bi 2212 phase appeared in the temperature range of 750 and $795^{\circ}C$ and single phase of Bi 2201 existed in the lower region than $785^{\circ}C$. Whereas, $O_3$ dependance on structural formation was scarcely observed regardless of the pressure variation. And high quality of c-axis oriented Bi 2212 thin film with $T_c$(onset) of about 90 K and $T_c$(zero) of about 45 K is obtained. Only a small amount of CuO in some films was observed as impurity, and no impurity phase such as $CaCuO_2$ was observed in all of the obtained films.

  • PDF

Design of 3-Fingers Type Internal Antenna for GPS/PCS Handsets (GPS/PCS 단말기용 3-Finger형 내장형 안테나 설계)

  • Bang Sang-Won;Jung Byung-Woon;Lee Hak-Yong;Park Myun-Joo;Lee Byungje
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.16 no.1 s.92
    • /
    • pp.1-8
    • /
    • 2005
  • This paper proposes a new type of a dual-band internal antenna for GPS/PCS handsets. The antenna has three monopoles in different lengths, and this structure is referred as a 3-fingers type antenna in this paper. The antenna with low-profile structure is designed to use internal space of handset maximally. The fabrication and the measurement are accomplished by attaching the 3-finger type antenna to the inside of a commercial handset. We obtain gain of 1.97 dBi$\~$0.66 dBi in the GPS band, and -0.92 dBi$\~$1.02 dBi in the PCS band and almost omni-directional patterns at all bands.