• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1993년도 추계학술대회
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• pp.194-197
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• 1993

A technique for fast image reduction or expansion, in which the reduction(expansion) factor is either any integer or any rational number M/L Is represented. The multiresolution is modeled as an interpolation and filtering followed by a decimation. The model enables frequency domain analysts of the muitiresolution representations as well as convenient design of the Kernels(filters). Using any rin linear phase(Type I) filters a fine to coarse multiresolution structure can be generated.

• Clinical and Experimental Reproductive Medicine
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• 제41권3호
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• pp.115-119
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• 2014

Objective: This study was designed to investigate the survival rate of vitrified mouse blastocysts depending on the presence or absence of sucrose in vitrification solution. Methods: Mouse two-cell embryos were collected and cultured to blastocysts. Two vitrification solutions were prepared. The control solution was composed of 25% glycerol, 25% ethylene glycol, and 0.5 M sucrose (G25E250.5S) containing 2.5 mL glycerol, 2.5 mL ethylene glycol, 2 mL SSS, and 0.855 g sucrose in 5 mL PB1. The experimental solution was composed of 25% glycerol and 25% ethylene glycol (G25E25) and contained 2.5 mL glycerol and 2.5 mL ethylene glycol in 5 mL PB1. Artificial shrinkage was conducted by aspirating the blastocoelic fluid using an ICSI pipette. To examine the effect of sucrose in the vitrification solution on the survival rate of mouse blastocysts, the shrunken-equilibrated blastocysts were rehydrated or vitrified after being exposed to one of the two vitrification solutions. After exposure and the vitrification-thawing process, the re-expansion rate and hatching rate were evaluated after 6 hours of in vitro culture. Results: The re-expansion rate of mouse blastocysts exposed to vitrification solution with and without sucrose were not different in the experimental solution (without sucrose) (98%) and the control solution (with sucrose) (92%) (p>0.05). The hatching rate was higher in the experimental solution (95%) than in the control solution (88%), but did not differ across two treatments (p>0.05). The re-expansion rate of mouse blastocysts vitrified in the control solution was 92% and 94%, respectively (p>0.05), and the hatching rate was higher in the experimental solution (90%) than in the control solution (74%) (p<0.05). Conclusion: Sucrose need not be added in vitrification solution for freezing of artificially shrunken mouse blastocysts.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2007년도 The 1st International Symposium on Advanced Magnetic Materials
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• pp.32.2-32.2
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• 2007

• Journal of the Korean Statistical Society
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• 제22권2호
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• pp.191-200
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• 1993

An asymptotic estimation problem of the unknown mean is studied under a general loss function. The proof of this result is based on the asymptotic expansion of the risk function. Also conditions for second order admissibility and minimaxity of a class of estimators depending only on the sample mean are established.

• 생명과학회지
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• 제27권10호
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• pp.1104-1110
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• 2017

히스톤 H3K4의 메칠화는 3T3-L1의 지방세포의 분화를 촉진하는 것으로 알려져 있으나, 히스톤 H3K4 메칠화 효소인 SET1A가 지방세포 분화를 조절하는지에 대해서는 보고된 바가 없다. 그러므로 본 연구에서는 SET1A의 3T3-L1 지방세포의 분화조절과 기전을 연구하였다. SET1A의 발현은 3T3-L1 지방세포 분화과정에서 증가함을 관찰하였다. 3T3-L1 지방전구세포에서 siRNA을 이용하여 SET1A의 발현을 감소시키면 3T3-L1 지방전구세포의 분화가 억제됨을 관찰하여 SET1A가 3T3-L1 지방전구세포의 분화를 촉진함을 알 수 있었다. 이에 대한 조절기전을 알기 위해, SET1A의 발현을 감소시킨 3T3-L1 지방전구세포의 세포증식을 측정한 결과, 분화 초기 단계인 분화 후 2일 동안 3T3-L1 지방세포의 증식이 감소하였다. 또한 분화 후 7일 동안 지방세포세포 분화 조절인자들의 발현을 측정한 결과, SET1A의 발현을 감소시킨 3T3-L1 지방세포에서 $PPAR{\gamma}$의 발현이 감소하였다. 위와 같은 연구결과를 바탕으로, SET1A는 분화초기단계에서는 mitotic clonal expansion 단계를 촉진하고, 분화후기단계에서는 $PPAR{\gamma}$의 발현을 증가시켜 3T3-L1 지방세포의 분화를 촉진함을 알 수 있었다.

• 한국식품과학회지
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• 제35권4호
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• pp.617-622
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• 2003

두유박 시리얼을 제조하는데 최적 배합비를 산출하기 위하여 혼합물 실험 계획법을 사용하였다. 두유박 $30{\sim}80%$과 옥분 $20{\sim}70%$의 제약조건으로 실험디자인을 하여 압출성형을 한 결과, 두유박 함량이 증가할수록 시리얼의 팽화율은 작아지고 용적 밀도는 높아진 반면에 옥분의 함량이 증가할수록 팽화율과 절단강도, 수분용해지수, 수분흡수지수를 증가시켰다. 시리얼의 색도에서는 두유박을 첨가할수록 어두워지고, 옥분은 $L^*$값과 $b^*$값에 큰 영향을 주었다. 모델화 및 분석을 통한 반응 결과는 팽화율, 절단강도, 수분흡착지수는 quadratic 모델이 설정되고, 용적밀도, 수분용해지수, 색도는 linear 모델이 설정되었다. 색도의 $a^*$을 제외한 모든 반응결과에서 5% 이내의 유의차를 보여주어 모델에 대한 적합성을 입증하였고, 예측된 반응식을 통하여 혼합물내의 성분들이 시리얼에 미치는 영향을 살펴볼 수 있었다. 결과적으로 각 반응의 모델에서 나타난 계수를 이용한 수치 최적화를 하였을 때, 두유박 46.19%, 옥분 53.81%의 최적 배합비가 산출되었다.

• Archives of Plastic Surgery
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• 제39권2호
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• pp.118-123
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• 2012

Background : An area of the skull exposed by burn injury has been covered by various methods including local flap, skin graft, or free flap surgery. Each method has disadvantages, such as postoperative alopecia or donor site morbidities. Due to the risk of osteomyelitis in the injured skull during the expansion period, tissue expansion was excluded from primary reconstruction. However, successful primary reconstruction was possible in burned skull by tissue expansion. Methods : From January 2000 to 2011, tissue expansion surgery was performed on 10 patients who had sustained electrical burn injuries. In the 3 initial cases, removal of the injured part of the skull and a bone graft was performed. In the latter 7 cases, the injured skull tissue was preserved and covered with a scalp flap directly to obtain natural bone healing and bone remodeling. Results : The mean age of patients was $49.9{\pm}12.2$ years, with 8 male and 2 female. The size of the burn wound was an average of $119.6{\pm}36.7cm^2$. The mean expansion duration was $65.5{\pm}5.6$ days, and the inflation volume was an average of $615{\pm}197.6mL$. Mean defect size was $122.2{\pm}34.9cm^2$. The complications including infection, hematoma, and the exposure of the expander were observed in 4 cases. Nonetheless, only 1 case required revision. Conclusions : Successful coverage was performed by tissue expansion surgery in burned skull primarily and no secondary reconstruction was needed. Although the risks of osteomyelitis during the expansion period were present, constant coverage of the injured skull and active wound treatment helped successful primary reconstruction of burned skull by tissue expansion.

• Biomolecules & Therapeutics
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• 제2권2호
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• pp.131-135
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• 1994

The effect of ginsenoside (GS) from Panax ginseng on basal and nitro-L-arginine suppressed nitric oxide (NO) production was studied in rat kidney. NO production was determined by conversion to [$^{14C}$]=L-citrulline from [$^{14C}$]-L-arginine both in whole kidney and three renal segments; glomerulus, cortex excluding glomerulus (cortex-) and medulla. Nitro-L-arginine (total dose of 30 mg/kg/3 days, i.p.) significantly reduced NO production in whole kidney, which was prevented by GS pretreatment (30 mg/kg/3 days, i.p.). Relative high dose of GS (120 mg/kg/4 days, i.p..) selectively increased NO production in glomerulus and cortex-. Protein content, on wet weight basis, in cortex- and glomerular DNA content were significantly reduced by GS. Our results confirm the existence of constitutive nitric oxide synthase in kidney and it seems that target nephron segment for volume expansion due to GS'NO-mediated vasodilation and for NO production stimulated by GS is cortex including glomerulus.lus.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2003년도 The Korea-Japan Plastics Processing Joint Seminar
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• pp.67-72
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• 2003

• 한국통신학회논문지
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• 제21권10호
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• pp.2710-2723
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• 1996

2-dimensional scattering problem of electromagnetic waves by a periodic strip grating on a grounded dielectric slab in case of oblique incidence and arbitrary polarization is analyed by the vector Floquet modal expansion method. Solution convergence versus number of Chebyshev polynomial terms representing the unknown strip current density and number of space harmonics is examined, and some numerical results such as variation of power of significant space harmonics(scattered mode) are compared with those obtained by previous method. In particaluar, the relationship between Bragg blazing phonmena and characteristics mode(current) on the srip is discussed in detail.