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Efficacy of Glycopyrrolate in Primary Hyperhidrosis Patients

  • Lee, Hyun-Ho;Kim, Do-Won;Kim, Do-Wan;Kim, Chan
    • The Korean Journal of Pain
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    • v.25 no.1
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    • pp.28-32
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    • 2012

  • Background: Primary hyperhidrosis is a disorder of excessive sweating, which shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oral glycopyrrolate is one of the treatments available. There are a few published studies on the use of glycopyrrolate given orally in the treatment of hyperhidrosis. Methods: Thies is study was a review of case notes in a series of 36 patients with primary hyperhidrosis. We made a comparison between the Keller's scale score of a pre-glycopyrrolate medication group and the Keller's scale score f a post-glycopyrrolate medication group. The Milanez de Campos score, Short Form_36 (SF-36) score, Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the two groups. Results: In the post-glycopyrrolate medication group, there were declines in Keller's scale, and Milanez de Campos scale score and BAI score (P < 0.001). In addition, there were increases in SF_36 score in the post-glycopyrrolate medication group (P = 0.03) However, no changes were seen in, BDI score and ANS score in the post-glycopyrrolate medication group (P < 0.001). Conclusions: Glycopyrrolate is an effective initial method of treating primary hyperhidrosis that, reduces anxiety and improve patients' quality of life.

  • https://doi.org/10.3344/kjp.2012.25.1.28 인용 PDF KSCI

A Comparison of the Clinical Characteristics of Panic Disorder with and without Generalized Anxiety Disorder (공황장애 환자에서 범불안장애 공존 유무에 따른 임상적 특징 비교)

  • Oh, Jongsoo;Jung, Sra;Choi, Tai-Kiu
    • Anxiety and mood
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    • v.13 no.1
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    • pp.10-16
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    • 2017

  • Objective : This study aimed to investigate differences in demographic, clinical characteristics, and quality of life between panic-disorder patients with generalized anxiety disorder (PD+GAD) and without generalized anxiety disorder (PD-GAD). Methods : We examined data from 218 patients diagnosed with PD+GAD (150 patients) and PD-GAD (68patients). The following instruments were applied: Stress coping strategies, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Panic Disorder Severity Scale (PDSS), Anxiety Sensitivity Index-Revised (ASI-R), Albany Panic and Phobia Questionnaire (APPQ), NEO-neuroticism(NEO-N), Short Form health survey-36 (SF-36). Results : Compared to the PD-GAD group, the PD+GAD group had higher scores in emotion-focused coping strategies and clinical severity, such as BDI, BAI, PDSS, ASI, APPQ, and neuroticism. The PD+ GAD group showed lower scores in most scales in SF-36 status than PD-GAD group. Conclusions : This study shows that PD+GAD patients are different from PD-GAD patients in coping strategies, clinical severity and quality of life. It emphasizes the need of personalized therapy in clinical approach among patients with PD+GAD.

  • https://doi.org/10.24986/anxmod.2017.13.1.002 인용 PDF

Test of Independence in a Markov Dependent Waiting-time Distribution

  • Bai, Do-Sun
    • Journal of Korean Institute of Industrial Engineers
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    • v.1 no.1
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    • pp.99-103
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    • 1975

  • A procedure for the test of independence of the observations and the null distribution are studied for a waiting-time distribution of the number of Bernoulli trials required to obtain a preassigned number of successes under Markov dependence. Selected critical values for the test statistic are tabulated.

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MULTIPLICITY OF SOLUTIONS FOR A CLASS OF NON-LOCAL ELLIPTIC OPERATORS SYSTEMS

  • Bai, Chuanzhi
    • Bulletin of the Korean Mathematical Society
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    • v.54 no.3
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    • pp.715-729
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    • 2017

  • In this paper, we investigate the existence and multiplicity of solutions for systems driven by two non-local integrodifferential operators with homogeneous Dirichlet boundary conditions. The main tools are the Saddle point theorem, Ekeland's variational principle and the Mountain pass theorem.

  • https://doi.org/10.4134/BKMS.b150489 인용 PDF KSCI