• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.525-526
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• 2006

Calcium-hexaluminate phase $(CA_6)$ is known to be effective for the crack shielding due to the spinel block crystal structure. In this study, we focused to the control of $CA_6$ morphology for good damage tolerance behavior in alumina and zirconia/calcium-hexaluminate $(CA_6)$ composites. Calcium-hexaluminate $(CA_6)$ composites were prepared from zirconia, alumina and calcium carbornate powders. Calcium-hexaluminate $(CA_6)$ phase was obtained by the solid reaction through the formation of intermediate phase $(CA_2)$. $CA_6$ phase showed the column type abnormal grain grown behavior composed of small blocks. Due to the typical microstructure of $CA_6$, alumina and zirconia/calcium-hexaluminate composites provide a well controlled crack propagation behavior.

• Archives of Pharmacal Research
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• v.20 no.6
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• pp.647-651
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• 1997

The 6, 6-dibromopenam 6 was treated with $CH_{3}/MgBr$ and carbaldehyde 5 to afford the 6-bromo-6-(1-hydroxy-1-methyl)penicillanate 7, which was reacted with acetic anhybride to give acetoxy compound 8. The deacetobromination of 8 with zinc and acetic acid gave 6-exomethylenpenams, Z-isomer 9 and E-isomer 10, which were oxidized to sulfones 11 and 12 by m-CPBA. The p-methoxybenzyl compounds were deprotected by $AlCl_{3}$ and neutralized to give the sodium salts 13, 14, and 15.

• Journal of Life Science
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• v.31 no.8
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• pp.729-735
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• 2021

Type 2 diabetes occurs when there is an abnormality in the tissue's ability to absorb glucose. Glucose uptake and metabolism by insulin are the basic mechanisms that maintain blood sugar. Glucose uptake goes through various signaling steps initiated by the binding of insulin to receptors on the cell surface. In line with the foregoing, the purpose of this study was to investigate the effect of 2,7-phloroglucinol-6,6-bieckol (PHB), an active compound isolated from Ecklonia cava, on glucose uptake in 3T3-L1 adipocytes. Notably, PHB increased glucose uptake in a dose-dependent manner owing to the enhanced glucose transporter type 4 (GLUT4) expression in the plasma membrane of 3T3-L1 adipocytes. These effects of PHB were attributed to the phosphorylation of insulin receptor substrate-1 and protein kinase B (PKB or AKT), as well as to the phosphoinositide 3-kinase (PI3K) activation in the insulin signaling pathway. PHB also stimulated 5' AMP-activated protein kinase (AMPK) phosphorylation and activation. The phosphorylation and activation of the PI3K/AKT and AMPK pathways by PHB were identified using wortmannin (a PI3K inhibitor) and compound C (an AMPK inhibitor). In this study, we showed that PHB can increase glucose uptake in 3T3-L1 adipocytes by promoting GLUT4 translocation to the plasma membrane via the PI3K and AMPK pathways. The results indicate that PHB may help improve insulin sensitivity.

• Proceedings of the Korean Information Science Society Conference
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• 2006.10d
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• pp.334-337
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• 2006

현재 전 세계는 IPv4 주소 자원의 고갈에 대비한 IPv6의 도입을 위해 국가 차원의 전략적인 노력을 기울이고 있으며, 이에 따라 IPv4망에서 IPv6망으로의 안정적인 전이를 위한 상호 운영기술이 지속적으로 개발되고 있다. 이러한 기술을 적용하기 위한 다양한 응용 프로그램의 운영을 위해서 IPv6 기반의 DNS 기술은 그 핵심적인 요소라 할 수 있다. 그러나 현재 IPv4로 이루어져 있는 환경에서 바로 IPv6 환경으로의 변경이 어렵기 때문에 IPv6 네트워크 환경으로의 전이 과정에서 발생되는 IPv4와 IPv6의 네트워크의 공존 환경에서 트래픽을 안정적으로 전달하기 위한 기술이 필요하게 되었다. 이런 IPv4와 IPv6 상호 운용 기술을 이용하여 본 논문에서는 IPv4와 IPv6가 혼재한 망에서 안정적인 IPv6 Recursive DNS을 구성하기 위하여 상호 운용 기술 중 터널링 기술을 이용한 IPv6 Recursive DNS 구성 방안을 제시하여 혼재한 IPv4 와 IPv6 DNS를 운영하기 위한 구성모델을 제안한다.

• Journal of Dairy Science and Biotechnology
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• v.35 no.4
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• pp.221-231
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• 2017

This study aimed to investigate the physiological characteristics and anti-obesity effects of a newly isolated bacterium, Lactobacillus plantarum K6. L. plantarum K6 showed good ${\alpha}-amylase$ inhibitory activity ($96.78{\pm}3.29%$), ${\alpha}-glucosidase$ inhibitory activity ($92.55{\pm}9.62%$), and lipase inhibitory activity ($85.17{\pm}0.79%$), and the strain inhibited the adipocyte differentiation of 3T3-L1 cells ($27.4{\pm}1.4%$) when present at a concentration of $100{\mu}g/mL$. L. plantarum K6 was isolated from kimchi and its physiological characteristics were investigated. A comparison of the sensitivity of the isolate to 15 different antibiotics showed that L. plantarum K6 is highly sensitive to erythromycin and highly resistant to vancomycin, ampicillin, and polymyxin B. This strain also showed high arylamidase and ${\beta}-galactosidase$ activities. Moreover, it was relatively tolerant to bile acid and low pH, and displayed resistance to Escherichia coli, Salmonella Typhimurium, Listeria monocytogenes, and Staphylococcus aureus, with rates of 51.8%, 42.4%, 61.6%, and 54.9%, respectively. No bio genic amines were produced. L. plantarum K6 also showed high adhesion activity to HT-29 cells compared to L. rhamnosus GG. These results demonstrate that Lactobacillus plantarum K6 has potential as a probiotic with anti-obesity effects.

• Journal of the Korea Institute of Military Science and Technology
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• v.17 no.6
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• pp.861-867
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• 2014

In the present study, the flow around a circular cylinder at $Re=3.6{\time}10^6$ is numerically simulated using URANS approach. The objective of this study is to evaluate the turbulence models(Realizable k-${\varepsilon}$, RNG k-${\varepsilon}$) through the prediction of the unsteady flow characteristics around the cylinder. The time-averaged drag coefficients and vortex shedding phenomenon in the wake region are compared to available experimental data and other numerical results. The simulation with Realizable k-${\varepsilon}$ model is found to be more dissipative due to large eddy viscosity predicted in the wake region while the simulation with RNG k-${\varepsilon}$ model predicts a complex vortex shedding phenomenon with more coherent structures realistically.

• Progress in Superconductivity
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• v.6 no.1
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• pp.46-51
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• 2004

We fabricated a resistive type superconducting fault current limiter (SFCL) of 3-phase $6.6 kV_{rms}$ / rating, based on YBCO thin films grown on sapphire substrates with a diameter off inch. Each element of the SFCL was designed to have the rated voltage of $600 V_{rms}$ $/35A_{rms}$. The elements produced a single phase with 8${\times}$6 components connected in series and parallel. In addition, a NiCr shunt resistor of 23 $\Omega$ was connected in parallel to each of them for simultaneous quenches between the elements. Prior to investigating the performance of the 3 phase SFCL, we examined the quench characteristics for 8 elements connected in series. For all elements, simultaneous quenches and equal voltage distribution within 10% deviation from the average were obtained. Based on these results, performance of the SFCL for single line-to-ground faults was investigated. The SFCL successfully limited the fault current of $10 kA_{ rms}$ below 816 $A_{peak}$ within 0.12 msec right after the fault occurred. During the quench process, average temperature of all components did not exceed 250 K, and the SFCL was totally safe during the whole operation.

• Proceedings of the KIEE Conference
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• 2001.07c
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• pp.1619-1622
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• 2001

Recently many researches on the diagnosis of stator winding insulation for large rotating machines have been developed sine the 1970s. Capacitive coupler has been the most widely used sensor for on-line partial discharge(PD) in rotating machines. The 105 [pF] ceramic coupler(CC) has been developed to continuously measure the PD activity in operating motor stator windings. This paper presents frequency characteristics and laboratory test to compare traditional 80 [pF] epoxy-mica coupler(EMC) and 105 [pF] CC for PD measurement in 6.6 [kV] stator windings.

• Archives of Pharmacal Research
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• v.18 no.5
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• pp.356-360
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• 1995

Two new 1-aryl-2-benzylmercapto-4-aryl-1,6-dihydro-1,3,5-triazine-6-thiones hvae been synthesized by known methods (Coerdeler et al., 1967). These triazines on treatment with thiourea as dealkylating agent, in acidic medium afforded the corresponding 1-ary-2-mercapto-4-aryl-1,6-dihydro-1,3,5-triazine-6-thione which on further reaction with different ${\alpha},{\;}{\beta}-unstaturated$ carbonyl compounds and aryl-cyanamide ydrochloride affordered the related adducts. Some of these compounds show appreciable antithyroidal activity.

• Proceedings of the KIEE Conference
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• 2005.07e
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• pp.97-99
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• 2005

현장에서 사용중 고압전선에 고장이 발생한 6.6kV 건식변압기 고장의 원인분석을 위하여 설계와 제조방식이 동일하고 사용기간이 비슷한 건식변압기에 대한 전기적 열적 시험을 실시하였다. 전기적 시험으로서는 교류 및 충격 내전압시험, 부분방전시험을 실시하였고 열적시험으로는 단락법을 사용하여 온도를 상승시켰으며, 내부 및 외부권선표면의 온도분포와 열화상에 의한 온도분포를 측정하였다. 시험결과 부분방전특성이 기준치에 비하여 높게 나타났으며, 권선온도분포는 사용한계온도이하인 것으로 분석되었다.