• Title/Summary/Keyword: Justification of use

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Radioactive waste sampling for characterisation - A Bayesian upgrade

  • Pyke, Caroline K.;Hiller, Peter J.;Koma, Yoshikazu;Ohki, Keiichi
    • Nuclear Engineering and Technology
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    • v.54 no.1
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    • pp.414-422
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    • 2022
  • Presented in this paper is a methodology for combining a Bayesian statistical approach with Data Quality Objectives (a structured decision-making method) to provide increased levels of confidence in analytical data when approaching a waste boundary. Development of sampling and analysis plans for the characterisation of radioactive waste often use a simple, one pass statistical approach as underpinning for the sampling schedule. Using a Bayesian statistical approach introduces the concept of Prior information giving an adaptive sample strategy based on previous knowledge. This aligns more closely with the iterative approach demanded of the most commonly used structured decision-making tool in this area (Data Quality Objectives) and the potential to provide a more fully underpinned justification than the more traditional statistical approach. The approach described has been developed in a UK regulatory context but is translated to a waste stream from the Fukushima Daiichi Nuclear Power Station to demonstrate how the methodology can be applied in this context to support decision making regarding the ultimate disposal option for radioactive waste in a more global context.

Drug Use Evaluation of Vancomycin in Hospitalized Patients of Surgery Departments (외과계 입원환자에 대한 Vancomycin의 약물사용 평가)

  • Lee, Young Mee;Choi, Kyung Eob
    • Korean Journal of Clinical Pharmacy
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    • v.9 no.1
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    • pp.35-43
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    • 1999
  • Over the last 50 years, a number of antibiotic agents have been developed and clinically used in the area of infectious diseases. Due to antimicrobial resistance problems and increasing health care costs, the rational use of antibiotics has been required. As a drug of choice to treat infections caused by MRSA, vancomycin has been extensively prescribed since the late 1970's. Recently, reports of vancomycin-resistant organisms such as VRE and VRSA have been increased to draw medical concerns. The objectives of this study were to evaluate the rational use of vancomycin and the appropriateness of the Restrictional Program of Antibiotic Utilization (RPAU) which has been operated at Samsung Medical Center. A retrospective chart review was performed in 132 hospitalized patients treated with vancomycin in the surgery departments from. January to June 1998. The guidelines of ASHP and HICPAC for vancomycin were modified and used as our criteria to determine the vancomycin DUE. In one hundred out of the patients, uses of vancomycin were approved by the Department of Infectious Diseases (DID) based on the RPAU. Vancomycin was appropriately used in $62.5\%$ of the 100 patients according to the criteria of justification of use, while $60.0\%,\;60.0\%,\;79.0\%,\;and\;51.0\%$ of the patients showed appropriate according to those of lab reports such as applicable culture obtained, pretreatment SCr, WBC and serum drug concentration monitoring, respectively. Although the rest 32 patients were not approved to receive vancomycin by the DID, twenty two percent continued receiving vancomycin treatment. This might result from the fact that the RPAU was started not before the use of antibiotics but in the middle of antimicrobial therapy. Continual education should be provide to the related health professionals and the RPAU should be simultaneously modified in order to increase the rate of appropriate uses of antibiotics.

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Changes of Total and Ionized Calcium following Cardiopulmonary Bypass (심폐관류에 따른 혈청칼슘의 변동)

  • 전상훈
    • Journal of Chest Surgery
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    • v.21 no.2
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    • pp.240-245
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    • 1988
  • This study was prospectively planned to realize the reduction of calcium ion in serum along with the cardiopulmonary bypass[CPB], to find out the cause of the reduction, and to verify the justification of the classical methods of calcium replacement. Nine patients with various open heart surgeries by CPB in 1987 wee selected at random. Calcium chloride was added as follows:: For each unit of ACD blood transfusion, 600mg of calcium chloride was added. In case of massive transfusion, 600 mg of calcium chloride was injected every 2 or 3 units of transfusion. On occasions such as weaning from CPB, or following defibrillation, or hypotension, weak myocardial contractility of the heart, calcium chloride was needed in an amount of 10 mg / kg. In ICU, calcium chloride was limited to use in low serum level or in emergency use. Total calcium decreased early bypass and progressively increased above the preoperative value during late bypass and three hours thereafter, Ionized calcium increased during late bypass and three hours following. Total and ionized calcium depicted similar patterns of change during open heart surgery. Decrease of the calcium at the early bypass was thought from reduction of total protein and alkalosis during bypass. Meanwhile, increase of both calciums during the end of surgery was presumably attributable to addition of calcium chloride in priming solution, injections of calcium chloride in the process of termination of bypass. We conclude that enough calcium was replaced by the classical methods of calcium supplement.

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Pragmatic Strategies of Self (Other) Presentation in Literary Texts: A Computational Approach

  • Khafaga, Ayman Farid
    • International Journal of Computer Science & Network Security
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    • v.22 no.2
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    • pp.223-231
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    • 2022
  • The application of computer software into the linguistic analysis of texts proves useful to arrive at concise and authentic results from large data texts. Based on this assumption, this paper employs a Computer-Aided Text Analysis (CATA) and a Critical Discourse Analysis (CDA) to explore the manipulative strategies of positive/negative presentation in Orwell's Animal Farm. More specifically, the paper attempts to explore the extent to which CATA software represented by the three variables of Frequency Distribution Analysis (FDA), Content Analysis (CA), and Key Word in Context (KWIC) incorporate with CDA decipher the manipulative purposes beyond positive presentation of selfness and negative presentation of otherness in the selected corpus. The analysis covers some CDA strategies, including justification, false statistics, and competency, for positive self-presentation; and accusation, criticism, and the use of ambiguous words for negative other-presentation. With the application of CATA, some words will be analyzed by showing their frequency distribution analysis as well as their contextual environment in the selected text to expose the extent to which they are employed as strategies of positive/negative presentation in the text under investigation. Findings show that CATA software contributes significantly to the linguistic analysis of large data texts. The paper recommends the use and application of the different CATA software in the stylistic and corpus linguistics studies.

How Do Consumers React to Scandals Involving Celebrity Endorsers and Endorsed Brands?

  • CHOI, Jieun
    • Journal of Distribution Science
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    • v.17 no.8
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    • pp.77-85
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    • 2019
  • Purpose - The use of celebrity endorsers is a strategy long-since used by companies to improve the persuasive impact of their company's advertising. However, much like anyone else, celebrities are flawed human beings, and therefore often find themselves involved in scandals. Companies must consider the potential of scandals when using a celebrity endorser to represent their brand or product. This research focuses on the process consumers use to justify scandals involving celebrity endorsers. Specifically, this research divides the justification processes used by consumers to maintain support for celebrities involved in a scandal into moral decoupling and moral rationalization and proposes antecedents and consequences for these processes. Methodology - To verify the hypotheses suggested by this study, an online survey was conducted, and data was analyzed using a structural equation model. Result - Results showed that consumer empathy for the celebrity endorser and external attribution of the scandal presented were positively related to moral decoupling and moral rationalization. In addition, moral rationalization was positively related to consumers' attitude towards the celebrity endorser, which also enhanced brand attitude. However, the relationship between moral decoupling and the consumer's attitude toward the celebrity endorser was not statistically significant. Conclusion - This research serves to expand the scope of available research on the persuasiveness of celebrity endorsers and provides practical guidelines for marketers.

Possible Linkage between Management of the Service Supply Chain and the Power to Influence Potential Customers for Airline Booking

  • Moon-Jeong KIM
    • Journal of Distribution Science
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    • v.21 no.5
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    • pp.93-102
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    • 2023
  • Purpose: This study aims to investigate a meaningful connection between the service supply chain and the power to influence potential customers for airline booking. This investigation will cover various topics, including customer service, product quality, and marketing strategies. Additionally, the literature review will examine the various strategies and tactics airlines use to influence customer behavior. Research design, data, and methodology: The data collection process conducted by the author could obtain the justification and establish the quality of the instrument between independent factor (Service Supply Chain) and dependent factor (Power to Influence Potential Customers), selecting peer-reviewed articles mostly for the current study. Results: The findings section thoroughly studied the research findings indicating a potential link between service supply chain management and the ability to persuade potential consumers to book an airline. The research findings will be explored concerning the numerous variables that may affect customers' decision-making in the airline business, the techniques used by airlines to sway consumers. Conclusions: The research has provided evidence that airlines use a variety of strategies to influence potential customers and that these strategies are generally successful in increasing customer loyalty and satisfaction, as well as sales. By utilizing these strategies, airlines can increase their customer base and profitability.

Medical Radiation Exposure in Children CT and Dose Reduction (소아 CT 촬영시 방사선 피폭과 저감화 방법)

  • Lee, Jeong-Keun;Jang, Seong-Joo;Jang, Young-Ill
    • The Journal of the Korea Contents Association
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    • v.14 no.1
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    • pp.356-363
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    • 2014
  • Recently pediatric CT has been performed by reduced dose according to tube current modulation이라고, this fact has a possibility more reduce a dose because of strong affect depend on tube current modulation. Almost all MDCT snow show and allow storage of the volume CT dose index (CTDIvol), dose length product (DLP), and effective dose estimations on dose reports, which are essential to assess patient radiation exposure and risks. To decrease these radiation exposure risks, the principles of justification and optimization should be followed. justification means that the examination must be medically indicated and useful. Results is using tube current modulation이라고 tend to the lower kV, the lower effective dose. In case of use a low dose CT protocol, we found a relatively lower effective dose than using tube current modulation. Average effective dose of our studies(brain, chest, abdomen-pelvis) less than 47%, 13.8%, 25.7% of germany reference dose, and 55.7%, 10.2%, 43.6% of UK(United Kingdom) reference dose respectively. when performed examination for reduced dose, we must use tube current modulation and low dose CT protocol including body-weight based tube current adaption.

Analysis of Influence Factors on the Intention to Reuse O2O Service in Domestic Accommodation (국내 숙박 O2O서비스의 재이용 의도에 미치는 영향요인 분석)

  • Kim, Jung-Kyun;Kim, Injai
    • The Journal of Information Systems
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    • v.29 no.4
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    • pp.25-43
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    • 2020
  • Purpose The purpose of this study is to gradually increase the use of O2O services in recent years. It is a part of our daily lives, and accommodation/leisure is a part of the growing use of O2O services. Based on various prior research related to O2O service, the Commission intends to establish the justification and necessity of empirical research and to establish the relationship between O2O service impact factors and practical value, customer satisfaction and reuse intention. Design/methodology/approach This study analyzed what factors affected the intention of re-use of domestic accommodation O2O services. This research model was proposed based on the preceding research paper, and reliability, diversity, economics, leisure, safety and personalization were used as independent variables, practical value and customer satisfaction are parameters, and reuse intent is composed of dependent variables. Within the last year, users of domestic accommodation applications were selected as users who used domestic accommodation applications more than once, and data of domestic accommodation application users were analyzed using the SPSS 25.0 and AMOS 20.0 programs. Findings The results of this study show that economic efficiency, safety and personalization have significant effects on practical values in the relationship between O2O service impact factors and their impact on practical values. On the other hand, reliability, diversity and leisure were found to have no significant impact on practical values. In terms of O2O service impact factors and their impact on customer satisfaction, leisure and safety have significant effects on customer satisfaction. On the other hand, reliability, diversity, economics, and individualization have shown no significant impact on customer satisfaction. Practical values, parameters, customer satisfaction, and re-use intent, which are dependent variables, were also shown to have significant effects on practical values and customer satisfaction in the relationship.

The Mediating Effect of the Outcome of Digital Device Use between Digital Informatization & Life Satisfaction (디지털정보화와 일상생활만족도의 관계: 디지털기기 이용성과의 매개 효과 분석)

  • Kim, Ban-Ya;Kwon, Jong-Sil
    • Informatization Policy
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    • v.29 no.2
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    • pp.91-105
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    • 2022
  • This study investigates the effects of different types of digital informatization (i.e. access, skill, utilization) on life satisfaction. The mediation effects of the outcome of digital device use between digital informatization and life satisfaction are also tested. The '2020 Survey on the Digital Divide' conducted by the National Information Society Agency was referenced for empirical analysis. The findings show that in general, digital informatization contributes to improving life satisfaction. In addition, the outcome of digital device use mediates the positive relationship between digital informatization and life satisfaction. However, the magnitudes of the effects of digital informatization and mediation effects differed according to the types of digital informatization. This study supports the necessity and justification for a digital informatization policy and provides valuable information that helps establish and promote digital informatization policies. In addition, this study helps to understand the determinants of the third-level digital divide information by examining the relationship between digital informatization and the outcome of digital device use.

PHASE-B PRE-SIMULATION USING BORON AND GADOLINIUM AS POISON IN THE MODERATOR SYSTEM FOR WOLSONG-1

  • Kim, Sung-Min;Kim, Hyeong-Taek;Donnelly, Jim;Marleau, Guy
    • Nuclear Engineering and Technology
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    • v.44 no.5
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    • pp.551-560
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    • 2012
  • The Wolsong-1 (W-1) Phase-B pre-simulations were carried out in preparation for tests to be conducted for the restart of the reactor after a major refurbishment project that included replacement of the pressure tube. These pre-simulations for Wolsong-1 Phase-B differ from those in the past that were performed for the Wolsong-1,2,3,4 tests in that these tests use the WIMS/DRAGON/RFSP-IST code suite for verification of the tests and gadolinium instead of the traditional PPV/MULTICELL/RFSP code system and boron as poison in the moderator system. The use of gadolinium is deemed not to have domestically accumulated experience gained from the previous Phase-B tests. Thus, it is appropriate to conduct a study in order to gain a correct understanding and interpretation of potential differences in test results stemming from using gadolinium rather than boron. Although the calibration of the reactivity device will not be noticeably different using boron and gadolinium at a constant moderator temperature, the temperature dependency of the neutronic behavior due to the presence of gadolinium in the moderator system might be pronounced. The results of the pre-simulations using gadolinium revealed that the moderator temperature reactivity coefficients indeed showed significant differences in comparison with those with boron. In order to secure the validity of the analysis results, the newly acquired WIMS/DRAGON/RFSP-IST code suite was verified against the W-2,3,4 Phase-B test results. The results of the new code suite verifications revealed some overall improvements in accuracy; justification of the use of the code can be claimed for the validation of the W-1 Phase-B test results.