• The Journal of Korean Medicine
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• v.29 no.5
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• pp.52-66
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• 2008

Objectives :Ginkgo-Chunghyul-dan (GCHD) is newly developed herbal medicine to prevent and treat stroke. In this study, we investigated whether the GCHD had antioxidant activity and anti-platelet aggregation effect in vitro and hypolipidemic activities in vivo. Methods :Anti-oxidant activity of GCHD was measured using the Blois method, anti-platelet effect of GCHD was assessed by the Born method, and hypolipidemic activities of GCHD were evaluated in corn oil- or Triton WR-1339-induced and cholesterol-fed rats. Results :GCHD showed anti-oxidant activity in the study inhibiting the formation of 1-diphenyl-2-picrylhydrazyl radicals and xanthine oxidase activity. GCHD had anti-platelet aggregation activity. GCHD significantly lowered total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) in high cholesterol diet and Triton WR-1339 induced model TG in corn oil-induced model. GCHD had no acute toxicity at a single dosage. Conclusion : These results suggest that GCHD has the potential to treat hyperlipidemia and stroke.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.3
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• pp.29-37
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• 2014

Objectives Osteoporosis is an impending problem in the rapidly aging society. The purpose of this study is to identify the effects of Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) on osteoporosis induced by ovariectomy in rats. Methods 24 rats were randomly assigned to a SHAM group, a control group, and a Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) group (n=8). Ovaries were extracted and for 8 weeks, the rats were given dry feeds and Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) group were given a mixture of dry feeds and Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$). At 8 weeks, their body weight, femur mass, tibia ash per body ratio, overall surface area and thickness of the trabeculae, overall surface area of the osteoblasts, and the number of osteoclasts were measured and levels of albumin, aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total-cholesterol, calcium and estradiol were recorded. Results There was no significant difference in the weight of the femur and the tibia ash per body ratio. The Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) group had significantly thicker trabeculae than the control group and showed a minimal increase of overall surface area of the trabeculae. The overall surface area of the osteoblasts and the number of osteoclasts decreased in the Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) group. There were no statistically significant differences in AST, ALT, ALP, total cholesterol, phosphorus, and estradiol levels. On the contrary the Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) group had significantly higher levels of Albumin, triglyceride, and calcium. Conclusions It can be concluded that oral intake of Yoohyangheukho-dan ($R{\check{u}}xi{\bar{a}}ngh{\bar{e}}ih{\check{u}}-d{\bar{a}}n$) prevents the thinning process of the trabeculae. Thus, it may have positive effects on the treatment and prevention of osteoporosis in postmenopausal women.

• Proceedings of the Korea Information Processing Society Conference
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• 2006.05a
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• pp.253-256
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• 2006

소프트웨어는 생명주기 전반에 거쳐 발생하는 요구사항 변경으로 수정이 불가피하다. 소프트웨어를 수정할 때 품질과 안정성을 유지하는 것은 중요한 문제이다. 본 논문에서는 무브 메소드(Move Method) 기법을 기초로 하여 리팩토링 적용요인을 제안하고, 로지스틱 회귀분석을 통하여 적용요인이 메소드의 위치를 결정지을 수 있는 요인임을 증명하는 방법에 대하여 살펴본다. 또한 객체지향 프로그램에서 메소드와 더불어 중요한 요소인 필드의 위치를 결정지을 수 있는 요인을 무브 필드(Move Field) 기법에 기초하여, 객체내 필드의 위치를 결정하기 위한 리팩토링 요인을 정의하고, 향후 연구과제에 대하여 논한다.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.2156-2159
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• 2011

본 연구에서는 접지시스템으로 부터 다양한 서지 및 노이즈 신호를 측정 진단하여 시스템에 오동작을 유발하는 원인을 규명하여 안정된 설비 운용을 확보한다. 오동작 및 설비 손상의 원인이 되는 노이즈 전류 및 간섭 현상을 제거하기 위해 운용중인 접지시스템의 성능 및 구조적 문제점을 데이터로 실측하였다. 진단 분석 결과를 이용하여 개선된 성능의 접지시스템 및 배선 구조를 제안하여 시공하였고, 개선 효과를 검증하기위해 시공 후 설비의 운용 상태 하에 접지 노이즈 신호를 재 측정하여 개선 전 측정 결과와 비교 분석하여 개선된 성능을 최종 확인하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2017.04a
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• pp.700-703
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• 2017

안전 필수 소프트웨어란, 소프트웨어의 결함으로 인해 사고가 일어났을 경우 사용자에게 치명적인 위해를 야기하는 소프트웨어를 의미한다. 안전 필수 소프트웨어는 다양한 산업에서 보편화 되고 있기 때문에 안전성이 확보된 소프트웨어를 사용자에게 제공해야하며, 잠재적인 결함이 사고로 이어질 수 있기에 안전 요소들에 대한 충분한 분석이 필요하다. 요구사항으로부터 위험 요소를 분석할 때에는 결함의 결과만을 보고 위험 등급을 부여하는 한계가 있다. 결함의 결과가 비록 같더라도 각기 다른 원인에 의해서 각기 다른 위험 수준을 갖기 때문이다. 본 논문에서는 각각의 기능들에 대해 안전성을 부여하고 우선순위를 선정하여 위험도가 높은 기능들에 대해서 우선적으로 분석할 수 있는 기법에 대해서 제안한다.

• 보존과학연구
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• s.21
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• pp.273-291
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• 2000

The perilla oil is painted to the wooden cultural properties of protection of wood and pigment. But that is happened to discolor and gather mold because of the long drying time. So we were put to the test for the improvement of this matter. The result is follows;1. The perilla oil, do not parched domestic Perilla japonica, add to the Japanese acid clay, later passing through the filter paper that the pore size is less than $7\mum$ 2. If the perilla oil add to the antiseptic of Thiazole origin, the mold is suppressed.3. In the painting of perilla oil, the existing Dan-chung paints one time (Luster generation in the more than two times) and the non-existing Dan-Chung paints two times.

• Journal of IKEEE
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• v.21 no.3
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• pp.264-267
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• 2017

In this paper, A low dropout (LDO) regulator that improves the power supply rejection ratio by using a noise canceling circuit is proposed. The noise rejection circuit between the error amplifier and the pass transistor is designed to reduce the influence of the pass transistor on the noise coming from the voltage source. The LDO regulator has the same regulation characteristics as the conventional LDO regulator. The proposed circuit uses 0.18um process and Cadence's Virtuoso and Specter simulator.

• The Journal of Internal Korean Medicine
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• v.22 no.4
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• pp.755-759
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• 2001

Acute Myocardica Infarction has high mortality and bad prognosis. We treated a 68 year-old female patient of acute myocardiac infacrtion to follow cerebral infarction. The chief complainment is right hemiplegia, dyspnea, chest discomfort, palpitation, anxiety, insomnia. The prognosis cannot be good, Because she has anterior wall infarction, cardiomegaly, conduction block, hypertention and she is 68 years old. We treated her with chiefly Nogyongdaebo-tang and Gongjin-dan, and gradually increased momentum. also we used self west medicine. The chief complainment was improved. She became to do cane walking by herself.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.597-600
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• 2005

The software streaming technology enables telematics software to be automatically updated through a wireless network. When the software starts running, software streaming system inspects its version and then, automatically download latest one. The software streaming system breaks the software into several pieces that are streamed to the user as needed. In this way, software streaming system can improves the telematics application load time while updating the software through wireless network. In our experiments, the application load time was reduced about 7 times compared to downloading whole software at best case.

• The Journal of Korean Medicine
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• v.29 no.5
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• pp.77-89
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• 2008

Objectives : This study evaluates the hair growth promoting effect of Yonnyuniksoogobon-dan on shaved C57BL6 mice. Methods : Yonnyuniksoogobon-dan was administered orally (Group I) and both orally and by skin application (Group II) once a day for 12 days. The experimental groups were compared to Control, which was orally administered physiological saline solution. Hair regrowth was photographically and histologically determined during the experimental period. The levels of hair growth cycle related factors (EGF, TGF-${\beta}$1) and vascular factors (VEGF, iNOS) were also determined by immunohistochemistry. On gross observation of hair growth, both Group I and Group II shaved C57BL6 mice showed accelerated hair regrowth. Results : The hair regrowth index of Group I increased significantly from 7 days (P<0.05) to 12 days (P<0.01) after shaving and that of Group II was significantly higher at 12 days (P<0.05). On histological observation, both Group I and Group II demonstrated histological improvement and increases in the number and diameter of the hair follicles. EGF expression on the root sheath of hair follicles was up-regulated in both Group I and II. TGF-${\beta}$1 expression on the root sheath of hair follicles was unchanged in both Group I and II. VEGF expression in the tissues surrounding hair follicles was up-regulated in both groups. iNOS expression in the tissues surrounding hair follicles was down-regulated in both groups. Conclusions : These results suggest that Yonnyuniksoogobon-dan promotes hair growth and this effect is related to up-regulation of EGF and VEFG expression and down-regulation of TGF-${\beta}$1 and iNOS expression on hair roots.