• Journal of the Korean Society of Child Welfare
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• no.59
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• pp.151-182
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• 2017

The purpose of this study was to understand the survivors who experienced and suffered through the tragic earthquake in Nepal. Individual interviews were conducted with 13 participatns, consisting of 5 children, 5 parents and 3 staff members. Analysis was done using photos, drawings and records. Identified themes included "daily routine, pleasure of life (life before the earthquake)," "survival from the crossroad of life and death (situation at the time of the earthquake)," "nonfunctional governmental system and impassioned foreigners who lend a helping hand (post earthquake recovery)", "trace of the day left everywhere (the current life),"and "desiring to get back up again (hope for future)."Based on the results, this study suggested policies and practical guideline for preventing and coping with disaster and supporting the survivors.

• Journal of Ecology and Environment
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• v.43 no.3
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• pp.314-319
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• 2019

Background: The dramatic worldwide decline in the butterfly species Leptalina unicolor (Bremer & Grey) is largely the result of continuous habitat decline and disturbance by humans. The discovery of a narrow habitat in riverside wetlands utilized by L. unicolor raises the hope that such restricted key areas could be rather easily protected. Results: Here, we explain the environmental variables and habitat characteristics that primarily influence the distribution of L. unicolor discovered at the riverside areas along the Geum River. L. unicolor larvae were found at 9 of 13 study sites, and their abundance was strongly positively correlated with plant biomass. Our investigation showed that among four plant species (Miscanthus sinensis, Spodiopogon cotulifer, Setaria viridis, and Imperata cylindrica), L. unicolor larvae were the most abundant on the leaves of M. sinensis. They were not abundant on the leaves of S. cotulifer, S. viridis, or I. cylindrica. Interestingly, the number of L. unicolor larvae was positively correlated with the coverage area ($m^2$) of M. sinensis (F = 41.7, $r^2=0.74$, P < 0.0001). Conclusions: It appears that water (e.g., wetlands, ponds, and watersides) located along the riverside areas along the Geum River is important for the constant maintenance and conservation of L. unicolor. This is based on the habitat characteristics (water preference) of M. sinensis, which is used as a habitat by L. unicolor larvae. However, the waterside is dry and terrestrialization is in progress owing to the decreased water levels and water supply caused by an opened weir. Hereafter, this area will likely require management to secure a stable habitat for L. unicolor.

• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.193-200
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• 2019

Ceramide metabolism is known to be an essential etiology for various diseases, such as atopic dermatitis and Gaucher disease. Glucosylceramide synthase (GCS) is a key enzyme for the synthesis of glucosylceramide (GlcCer), which is a main ceramide metabolism pathway in mammalian cells. In this article, we developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to determine GCS activity using synthetic non-natural sphingolipid C8-ceramide as a substrate. The reaction products, C8-GlcCer for GCS, could be separated on a C18 column by reverse-phase high-performance liquid chromatography (HPLC). Quantification was conducted using the multiple reaction monitoring (MRM) mode to monitor the precursor-to-product ion transitions of m/z $588.6{\rightarrow}264.4$ for C8-GlcCer at positive ionization mode. The calibration curve was established over the range of 0.625-160 ng/mL, and the correlation coefficient was larger than 0.999. This method was successfully applied to detect GCS in the human hepatocellular carcinoma cell line (HepG2 cells) and mouse peripheral blood mononuclear cells. We also evaluated the inhibition degree of a known GCS inhibitor 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) on GCS enzymatic activity and proved that this method could be successfully applied to GCS inhibitor screening of preventive and therapeutic drugs for ceramide metabolism diseases, such as atopic dermatitis and Gaucher disease.

• Journal of Acupuncture Research
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• v.38 no.2
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• pp.170-174
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• 2021

A patient diagnosed with Guillain-Barre syndrome (GBS) suffering from numbness in the toes and fingers, paralysis in the face, and back pain received intravenous immunoglobulin on December 28, 2019. Without an improvement in symptoms the patient was admitted to a Korean medicine hospital on January 1, 2020 to receive combined Korean medicine treatment including herbal medicine (Sipjeondaebo-tanggami and Hyangbujasunkipalmul-tang), acupuncture treatment, moxibustion, cupping treatment, and physical therapy. Treatment was administered over 51 days, of which 17 days were during hospitalization. Paralysis of facial muscle, and numbness in fingers and toes were evaluated using the Yanagihara score and numeric rating scale (NRS) score, respectively. Facial paralysis improved (21 to 40 based on Yanagihara score) and paresthesia of the hands and feet disappeared (NRS score 6-7 to NRS score 0). There were no side effects or sequela. This study suggested combined Korean medicine treatment may be effective for the treatment of GBS.

• Journal of Korean Clinical Nursing Research
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• v.26 no.3
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• pp.327-336
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• 2020

Purpose: The purpose of this study was to describe changes in positive psychological capital, organizational commitment and burnout according to work periods for new nurses. Methods: A longitudinal study was done using surveys of 91 nurses from a tertiary hospital located in Seoul, South Korea. Data were collected from these newly graduated nurses during the period from July 2018 to September 2019, three times (2 months, 4 months and 6 months after starting to work). Results: Hope of positive psychological capital decreased after 6 months of work (F=7.11, p=.001) and organizational commitment decreased after 4 months of work (F=15.30, p<.001). Factors influencing participants' burnout included the optimism of positive psychological capital and continuance of organizational commitment. These factors explained 51.3% of the variance in burnout (F=48.47, p<.001). Conclusion: Organizational support for new nurses is urgently needed. It is necessary to develop programs to strengthen the positive psychological capital of newly graduated nurses to reduce their burnout and to help their job adaptation.

• Korean journal of dermatology
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• v.56 no.9
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• pp.543-547
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• 2018

Wolf's isotopic response is defined as the occurrence of a new skin disorder at the site of another unrelated skin disease that has already healed. In most cases of isotopic response, the initial dermatosis is herpes infection, and the most frequent second dermatoses are granulomatous reactions. Various interpretations of this phenomenon have been attempted. However, the exact mechanism has not been identified yet. Herein, we report a case in which the secondary disease was segmental vitiligo that appeared over the same dermatomes of herpes zoster. A 71-year-old woman presented with well-defined, depigmented patches on the left chest and back. She had been diagnosed with herpes zoster on the same dermatomes and treated with an antiviral agent 3 years ago. Histological examination showed decreased basal melanin pigments and melanocytes. Consequently, the patient was diagnosed with segmental vitiligo based on the clinical and histological findings.

• Journal of Biomedical Engineering Research
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• v.42 no.5
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• pp.225-231
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• 2021

The purpose of this study was to investigate the effect on the activity of the upper trapezius and erector spinae according to the length difference of the backpack using electromyogram (EMG). We also conducted a study comparing the center of pressure (COP) and weight distribution before and after using Wii® balance board. Thirty individuals were randomly assigned to the experimental group (n=14) wearing a backpack with a short right strap length and a control group (n=16) wearing a backpack with the same strap length. Data were collected by dividing into groups, carring a 15% weight backpack and walking for 20 minutes on a treadmill. As a result of analyzing the EMG data, there was no significant change in the upper extremity muscle activity of the control group, but it was significantly decreased in the right upper trapezius activity of the experimental group (p<0.05). In addition, there was a significant change of COP in the experimental group (p<0.05), but there was no significant difference of the weight distribution in both groups. Recognizing mechanical changes in the body that may occur due to the asymmetry of the strap length is thought to be helpful for systematic ergonomic intervention according to changes in the external environment in the future.

• Korean Journal of Acupuncture
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• v.38 no.4
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• pp.317-323
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• 2021

The purpose of this study is to report a case diagnosed with cellulitis and ankle joint synovitis after acupuncture treatment. An 85-years old female suffering from low back pain was managed by acupuncture including BL60. After treatment, unintended ankle pain occurred. The pain was diagnosed with cellulitis and synovitis by MRI. The patient was transferred to the Western medical hospital, and ankle joint arthroscopic synovectomy was performed. It was difficult to find a clear relationship between acupuncture and ankle joint synovitis. But it would be reasonable to assume that cellulitis was associated with acupuncture needling and synovitis was followed. Serious adverse effects, such as septic arthritis, are rare, but need significant attention. For acupuncture treatment on the ankle, especially using BL60, the depth and manipulation should be carefully performed along with sterilization.

• Journal of the Korean Orthopaedic Association
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• v.55 no.4
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• pp.348-353
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• 2020

A 68-year-old man presented with a bed sore with pus discharge on lower back. Radiographs showed extensive destruction of the L4 vertebral body. Magnetic resonance imaging (MRI) showed fluid collection with an enhanced wall at the defect of the L4 vertebral body extending into both psoas muscles. The primary diagnosis was neuropathic spondylopathy, but infective spondylitis was not ruled out. Initially, he was treated with antibiotics for two weeks. A follow-up MRI showed no improvement of the abscess, so surgical exploration was done. Charcot spinal arthropathy resulted in extensive vertebral body destruction that may be similar to infectious spondylitis, particularly in the case with fluid accumulation due to rupture of dura.

• Journal of architectural history
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• v.31 no.3
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• pp.41-52
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• 2022

This study explains the han-ok. in Gae-sung, which was antique and traditional city. In view of the fact that these were located in Gae-sung in North Korea hence direct investigate is not possible. Since there was no comprehensive study of Gaeseong han-ok, we have no choice but to rely on fragmentary records and memory of Gaeseong people. In accordance from the Japanese colonial era's surveys and sketches as well as how they were illustrated in the novel. Hark back to the peoples' thought of the han-ok years when they ran the survey in 1920s, the results were as follows: First, there are many houses so various classes in Mi-Mang. Jeon Cheo-man's house was a representative example of a rich family in Gae-sung, Jeon Je-seong(Jeon's 2^nd son)'s house was located in Si-jeon(government licensed-markets) near by the South gate. In particular, Jeon Yi-seong(Jeon's 3rd son)'s house was in rural areas. He managed on immense ginseng field and worker's houses. Hae-ju's house was a small house off the track. Second, the outer house is low and the main house is high and neat. Lastly, it was confirmed that it corresponded to sketches recorded by architects, such as neat housekeeping, long stones used for various purposes, invisible flat gates, the appearance of old and old houses and the composition of each room.