• The Journal of Korean Medicine
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• v.31 no.3
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• pp.47-54
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• 2010

Objective: To derive information on the efficacy of Sam-chul-kun-bi-tang (SKT), by evaluating its anti-inflammatory effect. SKT is a widely-used herbal formula in traditional Korean medicine. In man y studies, plant-derived anti-inflammatory efficacies have been investigated for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory effects of SKT extract on LPS-stimulated RAW 264.7 cells. Methods: The production of nitric oxide (NO), prostaglandin $(PG)E_2$, tumor necrosis factor (TNF)-$\alpha$ and interleukin (IL)-6 were examined in a macrophage cell line, RAW 264.7 cells, in the presence of SKT. RAW 264.7 cells were incubated with LPS 1 ${\mu}g/mL$ and SKT for 18 hrs. The anti-inflammatory activity of SKT was investigated by carrageenan-induced paw edema in rats. The paw volume was measured at 2 and 4 hrs following carrageenan-induced paw edema in rats. Results: SKT showed inhibitory effect on $PGE_2$, TNF-$\alpha$ and IL-6 in LPS-stimulated RAW 264.7 cells. But SKT was not inhibitory effect on NO by LPS-stimulated RAW 264.7 cells. Administration of SKT (1 g/kg) also showed a reduction in carrageenan-induced paw edema on rats. Conclusion: These results suggest that SKT has anti-inflammatory activities in both in vitro and in vivo models.

• Korean Journal of Oriental Medicine
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• v.18 no.1
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• pp.59-74
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• 2012

Objective : The aim of this study is to investigate current status of Sasang constitutional medicine researches and to provide source in setting a development strategy and making a policy on the Sasang constitutional medicine. Method : This study analyzed trends in research as represented in the 142 articles of Korea Institute of Oriental Medicine in the field of Sasang constitution medicine from 2007 to 2010. Result : The main themes of studies were Sasang constitution clinical study (68, 47%) and developing instruments for measuring diagnosis (48, 33%), especially pulse diagnosis (25, 17%). Genetic researches and trends studies on Sasang constitutional medicine were respectively 17 (12%) and 8 (5%). As a result, Korea Institute of Oriental Medicine established Sasang clinical information bank, and discovered clinical character of Sasang constitution to develope various diagnosis tools include constitution survey form and pulse diagnosis instrument. Genetic researches also discover constitution related genes such as FTO and MC4R, and explore association between heredity and Sasang constitution. Conclusion : The above mentioned achievements of Korea Institute of Oriental Medicine were limited to diagnosis process, unquestionably studies for reproducibility and authenticity of constitution diagnosis were important mission of Sasang constitutional medicine. However, to develop the advance of Sasang constitutional medicine, not only constitution diagnosis but also constitutional treatment studies should be conducted.

• Journal of Oriental Neuropsychiatry
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• v.34 no.4
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• pp.487-487
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• 2023

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.97-105
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• 2008

Although the judgment of constitutions is given according to the Sasang Typology in domestic korean medicine hospitals and universities, the unified constitution clinical information has not been accumulated. Therefore, in this paper, based on collection items where oriental doctors and experts have already agreed, we construct the input system which correctly and effectively collects the clinical information of persons of which constitutions are distinguished explicitly. In the future, the input system could be utilized to collect clinical information continuously and will help to search and analyze the constitution clinical information.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.33-40
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• 2008

Revising 11 historical topography of Jecheon city we could notice that this territory was traditionally producing high quality medicinal plants. This view is supported as it was tributed to the King. Production of medicinal plants continue these days, Jecheon being one of the largest production of medicinal plants in Korea. Abundant production of diverse medicinal plants of high quality seems to be linked with the soil, climate and environmental characteristics unique of Jecheon. Therefore we propose to develop new type of herbal medicin drugs like Gobang(膏方) which could distinguish from other places. Gobang matchs well to the requirement of current days being convenient to carry and of good taste. Also is appropriate to treat chronic diseases. Its primordial abundant herbal medicines of high quality for the development of Gobang where Jecheon can provide.

• Journal of Acupuncture Research
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• v.29 no.5
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• pp.109-118
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• 2012

Objectives : The aim of this study was to evaluate the effectiveness and safety of acupuncture for chronic fatigue syndrome and idiopathic chronic fatigue. Methods : A randomized, controlled pilot trial was conducted. Twenty-four participants were randomized into one of the two groups: an acupuncture group(n=12) and wait-list group(n=12). The treatment group received 12 sessions of acupuncture over 4 weeks. Eight points($GV_{20}$; bilateral GB20, $BL_{11}$, $BL_{13}$, $BL_{15}$, $BL_{18}$, $BL_{20}$, and $BL_{23}$) were selected for needling. The control group did not receive acupuncture treatment during study period and follow-up were done in the $5^{th}$ and $9^{th}$ weeks after randomization in both groups. The primary outcome was fatigue severity scale(FSS) and the secondary outcomes included a short form of stress response inventory(SRI-short form), beck depression inventory(BDI), and insomnia severity index(ISI). Safety was assessed at every visit. Results : There were statistically significant differences in the between group values of FSS at $5^{th}$ weeks after randomization(p=0.0002), SRI-short form, BDI, and ISI at $5^{th}$, $9^{th}$ weeks after randomization(p<0.01). There were no adverse events. Conclusions : The results suggest that acupuncture is associated with benefits on the short-term outcomes in chronic fatigue syndrome and idiopathic chronic fatigue.

• Korean Journal of Oriental Medicine
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• v.18 no.3
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• pp.133-139
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• 2012

Objective : UMLS is 'Ontology' which establishes the database for medical terminology by gathering various medical vocabularies representing same fundamental concepts. Method : Although Chinese character are represented in the Chinese part of Korean Unicode system in a computer, writing of Chinese characters is vary depending on Chinese input systems and Chinese writers' levels of knowledge. As the result of this, representation of Chinese writing in a computer will be considerably different from an old Chinese document. Therefore, a meaningful relationship between digital Chinese terminology and translated Korean is necessary in order to build Ontology for Chinese medical terms from Oriental medical prescription in a computer system. Result : This research will present 1:1 mapping information among the Chinese characters used in the Oriental medical prescription with analysis of 'same character different sound' and 'same meaning different shape' in Chinese part of Unicode systems. Conclusions : Furthermore, the research will provide top-down menu of relationship between Chinese term and Korean term in medical prescription with assumption of that the Oriental medical prescription has its own unique meaning.

• Journal of Sasang Constitutional Medicine
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• v.28 no.1
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• pp.1-10
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• 2016

Objectives SCAT (Sasang Constitution Analysis Tool) is a system designed to provide the information needed to diagnose a sasang constitution diagnosis expert diagnosis. In order to determine the sasang constitution diagnosis requires the following four ways. This system provides objective information to the constitution diagnostic expert to collect such information.Methods SCAT was constructed by considering the user UI/UX to be easy to enter information. To provide a state of the subject in Table to make it easier to grasp the information of the subject also in constitution diagnostician.Results Provides objective data for experts to determine the constitutional history of the subject.Conclusions Professionals and ordinary users through the SCAT system can easily access the sasang constitution diagnosis. In the future through the advancement of the SCAT system will improve the user's convenience stability.

• Korean Journal of Oriental Medicine
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• v.13 no.1 s.19
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• pp.101-107
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• 2007

Aims: We have examined and analyzed trends of acupuncture related patents to understand the status of acupuncture technology and research trends of acupuncture in major countries including Korea, the United States, European Union and Japan. Methods: To analyze the patents, we searched and analyzed the total of 1,048 on-line DB based patents under time limit of July, 2006. Results: According to the search results, Korea is mostly superior compared to the others in number of domestic patents. However, Korea patents is inferior in number of international patents and leave much to be desired in industrial applications because of low patents barrier of personal patents and the absence of prospective clients. In addition, in this study, we show an index of international competitiveness and preliminary data of necessity of international cooperation in a field of acupuncture researches. Conclusion: These data suggest that Korea has strong possibility to recover competitiveness for guaranteeing valuable patents, if there are international cooperation and intensive managements of industries in advanced country markets.

• Korean Journal of Oriental Medicine
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• v.17 no.2
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• pp.101-106
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• 2011

Objectives : The aim of this study was to survey the usage frequency of Sasang constitutional herbal formula in the clinlcal field. Methods : We searched the case report forms from 2031 subjects in the 11 oriental hospitals and 10 oriental clinic. Subjects were diagnosed by the Sasang Constitution specialist in oriental hospital, who had remarkable improvement in their chief complain after Sasang Constitution medication. We counted the usage frequency of each constitutional herbal formula. Results and Conclusions : In TE type, Cheongsimnyeonja-tang, Yeoldahanso-tang, Jowiseungcheong-tang, Taeeumjowi-tang were used in high frequency. In SE type, various herbal formula were used in a similar frequency. In SY type, Yanggyeoksanhwa-tang, Hyeongbangjihwang-tang, Dokhwaljihwang-tang were used in high frequency. Additionally, the use of specific herbal formula was concentrated in SY type.