• Title/Summary/Keyword: Joint research and development

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A Study of Kosa Mart Re-design for the Development of Nadle Stores (나들가게 활성화를 위한 코사마트 재편에 관한 연구)

  • Park, Jung-Sub;Kwon, Moon-Kyu
    • Journal of Distribution Science
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    • v.14 no.10
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    • pp.153-164
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    • 2016
  • Purpose - In general, large companies have larger organizations, funds, and systems to provide more effective and efficient services in the market. However, development needs to support the livelihood of ordinary citizens who work for small businesses as well. This research suggests that a new distribution channel, called a "foothold style Kosa mart," that cooperates jointly with a distribution center and a large discount mart can provide direct solutions to small and mid-size distributors. This new distribution channel can achieve a limited type of "Nadle shop (small supermarket) foster project" related to building a joint distribution center and improvement in wholesale supply. Research design, data, and methodology - Data about the Korea distribution situation, the Nadle stores, and the logistics centers were collected from literature, Statistics Korea, journals, and reports. Specifically, we investigated information about Kosa Mart and Nadle stores. We focused on the redesign of the distribution center for the Nadle store. Results - The Kosa Mart distribution center now includes 18 warehouses, and has been handling 2000-3000 items. Most of the warehouses have been simply designed and items loaded and stored without refrigeration; thus, it is possible to store only products of certain manufactured goods. The current logistics center has no wholesale function because it failed to resolve the joint purchasing and product supply issues of competitively priced products. Conclusions - This study aimed to identify ways to strengthen the competitiveness of small- and medium-sized retailers. A Kosa Mart redesign aims to unifying the logistics center, stores, and customers. First, the joint wholesale logistics system, equipped with an integrated ordering system, needs to process customer orders and store orders at the same time. Second, excellent small business product development has to connect with production. Third, the store composition needs to support a shipping hub. Fourth, the Mart differentiates itself from convenience store goods by supplying regional and specialized products to customers. Fifth, a service buying agent and direct transactions between producers and consumers need to be established, and exhibits and displays of goods need to be improved.

Relocation of plastic hinge in exterior beam-column joints using inclined bars

  • P.Asha;R.Sundararajan;K.Kumar
    • Earthquakes and Structures
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    • v.27 no.4
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    • pp.317-329
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    • 2024
  • Recent earthquakes have demonstrated that even when the beams and columns in a reinforced concrete frame remain intact, the integrity of the whole structure is undermined if the joint where these members connect fails. A good seismic performance of reinforced concrete frames depends on their ability to absorb seismic energy through inelastic deformations and to avoid a sudden development of collapse mechanism in event of a strong earthquake shaking. The primary objective of this investigation is to move the plastic hinge away from the beam-column joint region and hence reducing the damage to the joint region. In this research, the seismic performance of exterior beam-column joints with four types of confinement in joint region and inclined bars from column to beam is investigated experimentally. Control specimens without inclined bars and four types of confinement Square Hoop, Square Spiral, Circular Hoop and Circular Spiral were tested along with inclined bars were tested. Seismic performance was determined via load-deflection response, ductility, stiffness, energy dissipation, strain of beam reinforcement and crack pattern. Out of the four specimens with inclined bars, seismic performance of joint with Square Spiral confinement gave the best performance in terms of all parameters.

miR-328-5p functions as a critical negative regulator in early endothelial inflammation and advanced atherosclerosis

  • Yangxia Zhang;Yingke Li;Zhisheng Han;Qingyang Huo;Longkai Ji;Xuejia Liu;Han Li;Xinxing Zhu;Zhipeng Hao
    • BMB Reports
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    • v.57 no.8
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    • pp.375-380
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    • 2024
  • Early proatherogenic inflammation constitutes a significant risk factor for atherogenesis development. Despite this, the precise molecular mechanisms driving this pathological progression largely remain elusive. Our study unveils a pivotal role for the microRNA miR-328-5p in dampening endothelial inflammation by modulating the stability of JUNB (JunB proto-oncogene). Perturbation of miR-328-5p levels results in heightened monocyte adhesion to endothelial cells and enhanced transendothelial migration, while its overexpression mitigates these inflammatory processes. Furthermore, miR-328-5p hinders macrophage polarization toward the pro-inflammatory M1 phenotype, and exerts a negative influence on atherosclerotic plaque formation in vivo. By pinpointing JUNB as a direct miR-328-5p target, our research underscores the potential of miR-328-5p as a therapeutic target for inflammatory atherosclerosis. Reintroduction of JUNB effectively counteracts the anti-atherosclerotic effects of miR-328-5p, highlighting the promise of pharmacological miR-328-5p targeting in managing inflammatory atherosclerosis.

Development of a Model for the Estimation of Knee Joint Moment at MVC (MVC 상태에서의 무릎관절 모멘트 추정을 위한 모델 개발)

  • Nam, Yoon-Su;Lee, Woo-Eun
    • Journal of Biomedical Engineering Research
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    • v.29 no.3
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    • pp.222-230
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    • 2008
  • This paper introduces a method of estimating the knee joint moment developed during MVC. By combining the Hill-type muscle model and analytic results on moment arm and musculotendon length change as a function of hip and knee joint angle, the knee joint moment at a specific knee joint angle during MVC is determined. Many differences between the estimated results and the experimental data are noted. It is believed that these differences originate from inaccurate information on the muscle-tendon parameters. The establishment of exact values for the subject's muscle parameters is almost impossible task. However, sensitivity analysis shows that the tendon slack length is the most critical parameter when applying the Hill-type muscle model. The effect of a change of this parameter on the muscle length force relationship is analyzed in detail.

Analysis of Research Papers Published in the Korean Journal of Clinical Laboratory Science from 1985 to 2012

  • Koo, Bon Kyung
    • Korean Journal of Clinical Laboratory Science
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    • v.45 no.4
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    • pp.180-187
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    • 2013
  • The author surveyed and analyzed the research papers of korean journal of clinical laboratory science (KJCLS) that have been posted for 28 years from 17 volumes in 1985 to 44 volumes in 2012 in the time of 50th anniversary of foundation of the korean association of medical technologists (KAMT) of in 2012. This study is aimed to provide members with basic materials helpful to research development and suggest development measures of journal. The author analyzed the number of papers, research field, type of papers, and number of authors based on the title of paper. The total number of papers is 916 and average number of paper is 33. The research field was biochemistry 167 (18.2%), microbiology 160 (17.4%), histology & cytology 99 (10.8%), molecular genetics 77 (8.5%), hematology 69 (7.5%), physiologic function 64 (7.0%), immunology 60 (6.5%), blood bank 33 (3.6%), radioimmunoassay 33 (3.6%), parasitology 27 (2.9%), quality control 18 (2.0%), urinalysis & body fluid 13 (1.4%), cytogenetics 12 (1.3%), flow cytometry analysis 6 (0.7%), and other articles were 78 (8.5%). Regarding the type of papers, original article was 777 (84.8%), case report 52 (5.7%), review 23 (2.5%), others 64 (7.0%). Regarding the number of paper authors, single author was 208 (22.7%), 2-man joint authors 178 (19.4%), 3-man joint authors 181 (19.8%), 4-man joint authors 151 (16.5%), over-5-man joint authors 198 (21.6%). The average number of papers was 33 for 28 years from 1985 to 2012, it is fewer than number of technologists and professors working currently regardless of the level of quantity and quality. The KAMT needs paper promoting measures and strategic investment on the scholarly journals that can aggressively promote to members and inspire research desire for korea citation index (KCI) registered article selection of KJCLS in the future.

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Development of a Snake Robot for Unstructured Environment (비정형 환경에 적용하기 위한 뱀 로봇 개발)

  • Shin, Hocheol;Kim, Chang-Hoi;Lee, Heung-Ho
    • The Journal of Korea Robotics Society
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    • v.8 no.4
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    • pp.247-255
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    • 2013
  • This paper shows the development of a snake robot (KAEROT-snake V) which consists of 16 1-DOF actuator modules and head module. The modules are connected serially and the joint axis of each module is rotated by $90^{\circ}$ with respect to the previous joint so that the snake robot can move in the 3D space. A tail actuator module includes slip-ring and metal connector. KAEROT-snake IV developed in prior research could move in the 3D space and climb up in a narrow pipe. But its design was not appropriate to the unstructured tough environment and its speed was somewhat slow. A new actuator module is designed to enclose all parts of the module so that any wire is not exposed. The size and weight of the new module was slightly reduced. And the rotation speed and torque of the joint was increased by about twice when compared with pre-module. An embedded controller was developed so small that it can be mounted inside the module. The performance of the developed robot was demonstrated through various locomotion experiments.

Traffic-induced vibrations at the wet joint during the widening of concrete bridges and non-interruption traffic control strategies

  • Junyong Zhou;Zunian Zhou;Liwen Zhang;Junping Zhang;Xuefei Shi
    • Computers and Concrete
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    • v.32 no.4
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    • pp.411-423
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    • 2023
  • The rapid development of road transport has increased the number of bridges that require widening. A critical issue in the construction of bridge widening is the influence of vibrations of the old bridge on the casting of wet joint concrete between the old and new bridges owing to the running traffic. Typically, the bridge is closed to traffic during the pouring of wet joint concrete, which negatively affects the existing transportation network. In this study, a newly developed microscopic traffic load modeling approach and the vehicle-bridge interaction theory are incorporated to develop a refined numerical framework for the analysis of random traffic-bridge coupled dynamics. This framework was used to investigate traffic-induced vibrations at the wet joint of a widened bridge. Based on an experimental study on the vibration resistance of wet joint concrete, traffic control strategies were proposed to ensure the construction performance of cast-in-site wet joint concrete under random traffic without interruption. The results show that the vibration displacement and frequency of the old bridge, estimated by the proposed framework, were comparable with those obtained from field measurements. Based on the target peak particle velocity and vibration amplitude of the wet joint concrete, it was found that traffic control measures, such as limiting vehicle gross weight and limiting traffic volume by closing an additional traffic lane, could ensure the construction performance of the wet joint concrete.

Development of Durability Enhancement Technology for Arc Weldings in Advanced High Strength Steel (AHSS) Chassis Parts (고장력강판 적용 샤시부품의 용접부 내구수명 향상기술 개발)

  • Lee, Kwang Bok;Oh, Seung Taik
    • Journal of Welding and Joining
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    • v.33 no.4
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    • pp.50-56
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    • 2015
  • In general, discontinuity of metallurgical and structural points of weld zone could decline the fatigue strength. For the lightweight trend, the AHSS application in automotive chassis is in-progress. However, there are few research reports on AHSS welds fatigue strength in especially automotive chassis parts. Therefore, in this study, we evaluated the effects of the factors affecting the AHSS welding fatigue strength. As the result, the stress concentration of weld bead is the most important factor for welding fatigue strength. For the enhancement of welding fatigue strength, we focused on reducing the stress concentration of the welding beads. So, we applied and proved the plasma welding process and GTAW (Gas Tungsten Arc Welding) dressing method. It was verified by uniaxial fatigue specimen, fatigue performance increased from 40 to 60% by applying TIG dressing method compared to the conventional GMAW (Gas Metal Arc Welding). These results could be recommended the enhancement of fatigue performance of AHSS.

Relocation of Youngduk Offshore Micro-earthquakes (영덕 앞바다 미소지진 발생위치 재결정)

  • Kim, Kwang-Hee;Ryoo, Yong-Gyu;Yu, Chan-Ho;Kang, Su-Young;Kim, Han-Joon
    • Geophysics and Geophysical Exploration
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    • v.14 no.4
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    • pp.267-273
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    • 2011
  • A cluster of micro-earthquakes in the transition zone between the continental and oceanic crust in the East Sea was relocated using the Joint Hypocenter Determination (JHD) method. In order to increase the number of available earthquakes and to take advantage of the high detection capability of the Korea National Seismic Network (KNSN), continuously recorded seismic data were reviewed to identify 56 micro-earthquakes occurring in a 20 km ${\times}$ 20 km region. The initial earthquake hypocenters were determined using a routine single event location method. Single event locations do not reveal any significant structures in the study area. After relocating the earthquake hypocenters using the JHD technique, the earthquakes were clustered and four potential faults responsible for earthquake generation in the subsurface were delineated. They are defined by two sub-vertical and two steeply south-dipping seismicities located next to each other.