• Journal of Dental Anesthesia and Pain Medicine
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• 제17권2호
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• pp.113-119
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• 2017

Background: The purpose of this study was to investigate the distribution of systemic diseases and medications in patients older than 65 years of age who visited the hospital for implant treatment, as well as to investigate basic information about surgical complications that may occur after insured implant treatment. Method: A total of 126 patients over 65 years of age were treated for implant surgery from October 1, 2013 to October 30, 2016. Electronic chart review was conducted to obtain medical records, which included sex, age, systemic diseases, medication(s) being taken, and control of the medications. Five patients were excluded due to lack of medical records giving information about systemic disease. Results: Of the 126 patients, 112 (88.9%) were taking medication due to systemic disease and 9 patients (7.1%) were not. The sex distribution was 71 women and 55 men and the highest proportion of patients were between 65 and 69 years old. The most common diseases were, from most to least frequent, hypertension, cardiovascular disease, diabetes, and osteoporosis. The drug groups that can cause major complications after dental treatment were classified as hemorrhagic, osteoporotic, and immunosuppressive agents, and were taken by 45 (35.7%), 22 (17.5%) and 4 (3.2%) patients, respectively. Conclusion: Given that 88.9% of the elderly patients who were eligible for insurance implant treatment had systemic disease, it is necessary to carefully evaluate patients' medical histories and their general conditions in order to prevent emergencies during implant surgery.

• 한국측량학회지
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• 제36권5호
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• pp.403-412
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• 2018

Recently, GNSS (Global Navigation Satellite System)-derived orthometric height determination has been studied to improve the time and cost-effectiveness of traditional leveling surveying. However, the accuracy of this new survey method was evaluated when unknown points are located lower than control points. In this study, the accuracy of GNSS-derived orthometric height was examined using TPs (Triangulation Points) to verify the stability of surveying in mountainous areas. The GNSS survey data were obtained from Mungyeong, Unbong/Hadong, Uljin, and Jangseong. Three unknown points were surrounded by more than three UCPs (Unified Control Points) or BMs (Benchmarks) following the guideline for applying GNSS-derived orthometric height determination. A newly developed national geoid model, KNGeoid17 (Korean National Geoid 2017), has been applied for determining the orthometric height. In comparison with the official orthometric heights of the TPs, the heights of the unknown points in Mungyeong and Unbong/Hadong differ by more than 20 cm. On the other hand, TPs in Uljin and Jangseong show 15-16 cm of local bias with respect to the official products. Since the precision of official orthometric heights of TPs is known to be about 10 cm, these errors exceed the limit of the precision. Therefore, the official products should be checked to offer more reliable results to surveyors. As an alternative method of verifying accuracy, three different GNSS post-processing software were applied, and the results from each software were compared. The results showed that the differences in the whole test areas did not exceed 5 cm. Therefore, it was concluded that the precision of the GNSS-derived orthometric height was less than 5 cm, even though the unknown points were higher than the control points.

• 한국측량학회지
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• 제38권2호
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• pp.153-163
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• 2020

After launching the GOCE (Gravity Field and Steady-State Ocean Circulation Explorer) which obtains high-frequency gravity signal using a gravity gradiometer, many research institutes are concentrating on the development of GGM (Global Geopotential Model) based on GOCE data and evaluating its precision. The precision of some GGMs was also evaluated in Korea. However, some studies dealt with GGMs constructed based on initial GOCE data or others applied a part of GNSS (Global Navigation Satellite System) / Leveling data on UCPs (Unified Control Points) for the precision evaluation. Now, GGMs which have a higher degree than EGM2008 (Earth Gravitational Model 2008) are available and UCPs were fully established at the end of 2019. Thus, EIGEN-6C4 (European Improved Gravity Field of the Earth by New techniques - 6C4), GECO (GOCE and EGM2008 Combined model), XGM2016 (Experimental Gravity Field Model 2016), SGG-UGM-1, XGM2019e_2159 were collected with EGM2008, and their precisions were assessed based on the GNSS/Leveling data on UCPs. Among GGMs, it was found that XGM2019e_2159 showed the minimum difference compared to a total of 5,313 points of GNSS/Leveling data. It is about a 1.5cm and 0.6cm level of improvement compare to EGM2008 and EIGEN-6C4. Especially, the local biases in the northern part of Gyeonggi-do, Jeju island shown in the EGM2008 was removed, so that both mean and standard deviation of the difference of XGM2019e_2159 to the GNSS/Leveling are homogeneous regardless of region (mountainous or plain area). NGA (National Geospatial-Intelligence Agency) is currently in progress in developing EGM2020 and XGM2019e_2159 is the experimentally published model of EGM2020. Therefore, it is expected that the improved GGM will be available shortly so that it is necessary to verify the precision of new GGMs consistently.

• 인지과학
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• 제14권3호
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• pp.23-36
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• 2003

학습에 대한 이해-기반 접근에 따르면 새로운 정보는 기존의 배경지식과 통합되어 정신표상을 형성하며 이는 다른 새로운 정보를 결합하는데 사용된다고 가정한다. 지시문을 통한 학습상황에서 인간과 계산적 모형의 수행비교를 통해 이 접근법이 타당하다는 것을 보여주었다. 구성-통합 이론 (Kintsch, 1988; 1998)에 근거한 계산적 모형 (ADAPT-UNIX)은 사용자들이 UNIX 복합 명령문을 생성하는데 도움을 주기위해 제시된 지시문 학습에 높은 예측력을 보였다. 더불어, 제시된 지시문을 사용하여 올바른 복합명령문을 생성하는 과제수행도 실제 인간수행과 높은 유사성 보였다. 배경지식의 수준에 따라 지시문이 학습과 적용에 차별적인 영향을 미친다는 교육적 함의와 이해-기반 인지모델의 이론적 함의가 논의되었다.

• 한국초등과학교육학회지:초등과학교육
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• 제35권4호
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• pp.416-425
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• 2016

As curriculum statements require addressing ethical and social issues which are raised by modern science and technology, the ability to perceive ethical and social issues regarding science is necessary for teachers to introduce socio-scientific issues (SSI) in their science class. The purpose of this study is to explore elementary school teachers' ethical sensitivity on SSI and attempts to give implications for teacher education. To explore the ethical sensitivity in the context of SSI, the revised version of the Test for Ethical Sensitivity on Science (TESS) was used. Two socio-scientific issues (genetic engineering and radioactive waste) were provided to read and write down five possible questions they believed should be considered before reaching a decision. Data was collected from eighty-two elementary school teachers in Korea. To analyze the ethical sensitivity, the responses including ethical considerations were analyzed by situation and ethical issues. The result showed that 81 out of 82 teacher participants provided at least more than one ethical consideration on each scenario of this study. However, not many teacher could raise various ethical issues and situation that ethical issue might occur. There were only a few teaches who could consider all the situations, 'process of scientific research', 'application of science and technology', and 'science influenced by society', that ethical issues might occur. Especially, teachers failed to consider that the ethical issue can occur in the situation when science is influenced by society. Based on the results, we suggest that during teacher education teachers need to experience finding various ethical issues that can occur in the context of SSI and especially considering the ethical issues when science is influenced by society.

• 한국실내디자인학회논문집
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• 제27권3호
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• pp.14-23
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• 2018

The spatial planning of the elderly care facility plans is analyzed using space syntax in terms of encouraging the social interaction of the residents in this study. First, through the visibility graph analysis, openness and accessibility of space is analysed. Second, the walking behavior of residents through agent analysis model is simulated. Third, the space planning methods for the elderly care facilities are proposed based on the results. The results are as follows. According to the visibility graph analysis, the main corridor has high visual openness and high accessibility. The visual openness and accessibility of the unit living room, where social interaction among residents is possible in each unit, is low. Space planning is needed to increase direct protection and observation of employees to the unit living room. The location of the nurse station that manages the entire floor needs to be located where the openness and accessibility is most high. The nursing station should have a high degree of connectivity to the entire space, so that any accidents can be managed and contact is accessible. Through the agent simulation the flow from the center to each unit space is highest in the corridor space and the inflow to the private rooms and the living room are similar. Therefore, it is necessary to plan the accessibility of the unit living room more for the natural inflow of residents.

• 한국방사선학회논문지
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• 제8권2호
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• pp.65-74
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• 2014

본 연구에서는 에너지 변화에 의하여 발생하는 콤프턴 산란이 화질에 영향을 미친다는 것을 증명하기 위하여 웨이브릿 변환으로 신호의 특성을 추출하였다. 추출된 데이터를 분석하여 에너지의 변화에 따른 산란선의 화질영향 정도를 평가하고자 하였다. 이를 위하여 공학용 도구인 MatLab Tool을 이용하여 프로그램을 작성하였고, 작성된 프로그램을 이용하여 관전압 증가에 따른 산란선의 변화를 평가하였다. 평가결과 CR과 DR 모두 관전압 변화에 따라서 고주파영역의 주파수 변화가 있는 것으로 보아 콤프턴 산란선의 영향이 있는 것으로 나타났다. 급격한 주파수의 변화가 나타나는 관전압 영역이 CR은 80 kVp, DR은 90 kVp로 나타난 것으로 보아 DR의 검출기는 에너지에 대한 민감도가 낮은 것으로 알 수 있다. 결론적으로 본 연구의 결과로 보아 CR보다는 DR이 에너지가 높은 방사선에 민감한 것으로 나타났다. 본 연구의 결과는 공학용 도구인 MatLab Tool을 이용한 영상의 화질평가 방법이 공식적인 화질평가의 방법으로 인정되어 유용하게 적용될 것을 기대한다.

• 한국실내디자인학회논문집
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• 제25권5호
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• pp.121-129
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• 2016

With the ingenious properties of unconstrained formativeness and frank expression of materiality the exposed concrete became popular with numerous architectures. The application of the exposed concrete has expanded to indoor environments such as commercial and residential spaces beyond the building exteriors with the uncompromising nature of its materiality. The purpose of this study is to conduct sensibility evaluation of the exposed concrete finish in interior spaces. The sensibility evaluation is conducted through a survey on a set of space models of the exposed concrete finish. The three rendered space models were evaluated by emotional vocabulary of 18 pairs of words. The result were as follows: First, the emotions derived from the exposed concrete finish are 'modern', 'cold', 'simple', 'restrained', 'rough', 'dark', 'new', 'chic', 'familiar' and 'eco-friendly'. Second, three sets of space models with alternative materials on walls and floors in exposed concrete interior space showed clear difference in sensibility. A space with the exposed concrete finish on the floor, the walls and the ceiling showed the results of 'cold', 'dark', 'rational' and 'masculine'. In the exposed concrete finish environment with wood flooring 'comfortable', 'warm', 'bright' senses and with white paint finish on the wall 'bright', 'practical', 'ordinary' and 'restrained' senses were obtained. Third, all three images achieved senses of 'chic', 'modern', 'new', 'pleasant', 'environment friendly' and 'satisfactory'. The modernity and stylish expressions of the exposed concrete finish were kept with the application of different material finishes as well as complementing its cold and rough expressions with warmth and brightness.

• Journal of Microbiology and Biotechnology
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• 제23권9호
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• pp.1293-1303
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• 2013

Antibiotic resistance of soilborne Acinetobacter species has been poorly explored. In this study, norfloxacin resistance of a soil bacterium, Acinetobacter oleivorans DR1, was investigated. The frequencies of mutant appearance of all tested non-pathogenic Acinetobacter strains were lower than those of pathogenic strains under minimum inhibitory concentration (MIC). When the quinolone-resistance-determining region of the gyrA gene was examined, only one mutant (His78Asn) out of 10 resistant variants had a mutation. Whole transcriptome analysis using a RNA-Seq demonstrated that genes involved in SOS response and DNA repair were significantly up-regulated by norfloxacin. Determining the MICs of survival cells after norfloxacin treatment confirmed some of those cells were indeed persister cells. Ten colonies, randomly selected from among those that survived in the presence of norfloxacin, did not exhibit increased MIC. Thus, both the low mutation frequency of the target gene and SOS response under norfloxacin suggested that persister formation might contribute to the resistance of DR1 against norfloxacin. The persister frequency increased without a change in MIC when stationary phase cells, low growth rates conditions, and growth-deficient dnaJ mutant were used. Taken together, our comprehensive approach, which included mutational analysis of the target gene, persister formation assays, and RNA sequencing, indicated that DR1 survival when exposed to norfloxacin is related not only to target gene mutation but also to persister formation, possibly through up-regulation of the SOS response and DNA repair genes.

• 한국결정성장학회지
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• 제26권6호
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• pp.232-237
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• 2016

약물의 공결정 형성은 결정구조를 디자인하여 물리적인 성질을 제어하는 방법으로 각광받고 있다. 특히, 밀링 결정화법은 약물 공결정의 형성 여부를 판단하기 위한 스크리닝 기법으로 널리 사용되고 있는데, 대부분의 경우에 소량의 액체를 첨가하는 것이 필요하다. 본 연구에서는 액체의 첨가가 없는 밀링법을 가능하게 하기 위해서, ibuprofen/nicotinamide의 공결정화에 온도가 미치는 영향을 살폈다. 액체질소 냉각 온도와 상온에서의 밀링을 비교하였을 때, 액체질소 냉각 상태에서 공결정화가 상대적으로 효과적으로 진행된 것을 XRD, DSC 등의 분석법을 이용하여 확인하였다. 이러한 결과는 원료 물질의 유리전이 온도 이하에서 밀링하였을 때 분자의 운동성이 제한되어, 원료 결정구조의 파쇄와 공결정 유도가 효과적으로 일어나는 것으로 해석할 수 있다. 본 결과가 약물 밀링 공결정화에 응용되기 위해서는 여러 약물 공결정에 대한 추가 연구가 필요하다.