• Journal of Microbiology
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• v.39 no.1
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• pp.11-16
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• 2001

Tentative identification of Leuconostoc lactis IH23 isolated from kimchi (a fermented vegetable product) has been described previously with 16S rDNA sequencing (Choi, 1., M. Sc. Thesis Inha Univ.1999). This strain produced the slime identified as dextran based on IR, $\^$13/C- and $^1$H-NMR spectroscopic results. Further study proved that the isolate IH23 belongs to a homogeneous genetic group with L. lactis DSM 20202$\^$T/ and L. argentinum DSM 8581$\^$T/. The results showed DNA-DNA homology of 99-100%, 16S rDNA gene sequence similarity (97.7% ), and a phylogenetic relationship although L. argentinum DSM 8581$\^$T/ had lower homology (80-91%). These data indicate that L. argentinum DSM 8581$\^$T/ and the isolate IH23 belong to an identical species with L. lactis DSM 20202$\^$T/at the genetic level, although in carbohydrate fermentation, the isolate IH23 was mast closely related to L. argentinum DSM 8581$\^$T/ and quite different from L. lactis DSM 20202$\^$T/. Here we first report the isolation of consistent phenotypic variation in Leuconostoc lactis. We also emphasize that the nomenclature of subspecies needs to be differentiated into the three strains mentioned above in Leuconostoc lactis.

• Journal of Genetic Medicine
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• v.16 no.2
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• pp.81-84
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• 2019

Clinicians often have difficulties diagnosing patients with subtle phenotypes of Noonan syndrome phenotypes. Facial recognition technology can help in the identification of several genetic syndromes with facial dysmorphic features, especially those with mild or atypical phenotypes. A patient visited our clinic at 5 years of age with short stature. She was administered growth hormone treatment for 6 years, but her growth curve was still below the 3rd percentile. She and her mother had wide-spaced eyes and short stature, but there were no other remarkable features of a genetic syndrome. We analyzed their photographs using a smartphone facial recognition application. The results suggested Noonan syndrome; therefore, we performed targeted next-generation sequencing of genes associated with short stature. The results showed that they had a mutation on the PTPN11 gene known as the pathogenic mutation of Noonan syndrome. Facial recognition technology can help in the diagnosis of Noonan syndrome and other genetic syndromes, especially in patients with mild phenotypes.

• Journal of the Korean Geographical Society
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• v.29 no.1
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• pp.39-45
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• 1994

One of the major problems comparing the old map, Daedongyojido, with modern maps in order to measure the spatial error of the map it a projection of the modern map selected. This study focuses on the map projection of Daedongyojido. Three different approaches are used: comparing the spatial pattern of Daedongyojido with maps of different projection, examining materials related to old maps and books which were written by Jeongho Kim directly or indirectly, and the data sets which were available at the mid nineteenth century and could be used for map production. A couple of map projections are possible to that of Daedongyojido, but TM(Transverse Mercator) projection is one of the closest projections.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.16 no.1
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• pp.44-51
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• 2016

Recently, artificial intelligence has reached the level of top information technologies that will have significant influence over many aspects of our future lifestyles. In particular, in the fields of machine learning technologies for classification and decision-making, there have been a lot of research efforts for solving estimation and control problems that appear in the various kinds of portfolio management problems via data-driven approaches. Note that these modern data-driven approaches, which try to find solutions to the problems based on relevant empirical data rather than mathematical analyses, are useful particularly in practical application domains. In this paper, we consider some applications of modern data-driven machine learning methods for portfolio management problems. More precisely, we apply a simplified version of the sparse Gaussian process (GP) classification method for classifying users' sensitivity with respect to financial risk, and then present two portfolio management issues in which the GP application results can be useful. Experimental results show that the GP applications work well in handling simulated data sets.

• BMB Reports
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• v.50 no.5
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• pp.257-262
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• 2017

The subcellular localization of Bax plays a crucial role during apoptosis. In response to apoptotic stimuli, Bax translocates from the cytoplasm to the mitochondria, where it promotes the release of cytochrome c to the cytoplasm. In cells infected with HSV-1, apoptosis is triggered or blocked by diverse mechanisms. In this study, we demonstrate how HSV-1 ICP27 induces apoptosis and modulates mitochondrial membrane potential in HEK 293T cells. We found that ICP27 interacts with $14-3-3{\theta}$ which sequesters Bax to the cytoplasm. In addition, ICP27 promotes the translocation of Bax to the mitochondria by inhibiting the interaction between $14-3-3{\theta}$ and Bax. Our findings may provide a novel apoptotic regulatory pathway induced by ICP27 during HSV-1 infection.

• IMMUNE NETWORK
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• v.14 no.6
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• pp.277-288
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• 2014

T cells are central players in the regulation of adaptive immunity and immune tolerance. In the periphery, T cell differentiation for maturation and effector function is regulated by a number of factors. Various factors such as antigens, co-stimulation signals, and cytokines regulate T cell differentiation into functionally specialized effector and regulatory T cells. Other factors such as nutrients, micronutrients, nuclear hormones and microbial products provide important environmental cues for T cell differentiation. A mounting body of evidence indicates that the microbial metabolites short-chain fatty acids (SCFAs) have profound effects on T cells and directly and indirectly regulate their differentiation. We review the current status of our understanding of SCFA functions in regulation of peripheral T cell activity and discuss their impact on tissue inflammation.

• Journal of Magnetics
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• v.20 no.2
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• pp.120-128
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• 2015

Beam-quality of medical linac evaluations vary by diverse factors. Because conventional beam-quality evaluation methods yield fragmentary results, a new beam-evaluation method is suggested, and its feasibility is evaluated. The PDDs (percentage depth doses) of 6 MV (Mega-voltage) and 10 MV photon, R (Range) of a 6 MeV (Mega Electron-voltage) and 9 MeV electron were measured and compared with the conventional evaluation methods, and the improved methods $PDD^{10}{_5}$, $PDD^{20}{_{10}}$, $PDD^{30}{_{20}}$, $PDD^{20}{_5}$, $PDD^{30}{_{10}}$, and $R^{70}{_{50}}$, $R^{50}{_{30}}$, $R^{70}{_{30}}$ as the magnetic field of the bending magnet was changed to +2% to -2%, and the results were compared. The comparison showed that the improved methods exhibit a higher discrimination than the conventional methods in each energy regime. $PDD^{10}{_5}$, $PDD^{30}{_{20}}$, $PDD^{30}{_{10}}$ and $R^{70}{_{50}}$, $R^{50}{_{30}}$ should be applied. These methods exhibit a higher discrimination in each energy regime than conventional beam-quality evaluation methods; therefore, they should be used for beam-quality evaluation according to the magnetic field variation.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2017.05a
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• pp.297-300
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• 2017

A drastic pressure increment at the combustor inlet induced thermal choking is inevitable during scram-to-ramjet transitions. This phenomenon which is called by Non-Allowable Region(NAR) was observed on the excessive increment in the equivalent ratio. However, many studies were not investigated about factors which affects a variation of NAR. In the present study, a variation of NAR with regard to Mach number in the inlet of isolator is numerically and analytically analyzed. The conclusions from the investigation show that increasing the Mach number in the isolator inlet enlarged in the range of NAR.

• Korean Journal of Environmental Biology
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• v.40 no.1
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• pp.87-98
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• 2022

In this study, the community structure of marine benthic invertebrates was examined to evaluate the differences between the west, south, and east coasts of Korea and to identify the indicator species representing each region. Acrylic attachment plate sets were installed in Jeongok, Mokpo, Tongyeong, Yangpo, and Gangreung, and the invertebrate fauna thus captured were identified. Monitoring was performed in each area from March 2017 to May 2018. Water depth, temperature, and salinity at each location were measured to determine the potential influence of abiotic factors on the community structure. As a result, the mean depth of plates installed and the water temperature were significantly different in each area. A total of 32 invertebrate species were identified in all localities, and the most significant difference in the species compositions was found between Mokpo and Gangreung. The community structure differed significantly with a change in the plate depth, and a larger number of indicator species appeared on shallower plates. Finally, we determined the community structure of benthic invertebrates in different geographical regions of the Korean ocean by characterizing the dominant invertebrate taxa and the indicator species at each site.

• Journal of Korean Society on Water Environment
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• v.28 no.1
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• pp.18-25
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• 2012

For effective watershed management, it is very important to select the tributaries through selection and concentration of targeted tributary catchments for improving water quality within the limited financial conditions. This study introduced the selection and diagnosis procedure of tributary catchments for improving water quality at Chungcheongnam-do based on water quality and flowrate monitoring, stream grouping method. The tributaries with high value of water quality and flowrate were selected for improving water quality according to stream grouping method. The diagnosis of selected tributaries for improving water quality was performed with analysis of the pollution load (generated, discharged, delivered) and point source discharged pollution load density. The plans for improving water quality of tributaries were suggested thorough various diagnosis of tributary catchments. For improving water quality of tributaries in Chungcheongnam-do, the tributary catchments in the Dangjin, Asan, Yesan, Cheonan, Hongseong area should be preferentially considered. The water quality improving plans for those tributary catchments, in accordance with the reduction of sources of pollution by population and livestock, should be established.