• 보건의료산업학회지
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• 제6권4호
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• pp.13-25
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• 2012

There is growing evidence that substance use such as tobacco or alcohol consumption influences health disparity among adolescents. Previous research papers have shown an inconsistency in the relationship between socio-economic status (SES) and substance use in adolescents. However, little is known about socio-economic differences in unhealthy behaviors among Korean adolescents. The purpose of the present study is to explore associations between SES and substance use in Korean adolescents. The analysis was performed using data from the 2009 Korean Youth Risk Behavior Web-based Survey (YRBS), which included a nationally representative sample of middle and high school students. Drinking/heavy drinking and smoking/daily smoking behavior indices were used for dependent variables, and perceived economic status, family affluence score, parents' education were used for independent variables. Chi-square test were used to compare tobacco and alcohol consumption among 3 SES groups. Logistic regression models were used to identify statistically significant socio-economic factors after adjusting other covariates. Higher perceived economic status and higher family affluence were associated with higher rates of smoking, daily smoking, drinking, and heavy drinking, while lower level of parents' education was related to higher use of tobacco and alcohol. Socio-economic status significantly influences health behaviors in adolescents, and it may consequently affect health disparity in their adulthood. Therefore, there is a need of continuous monitoring and follow-up research of health disparity among adolescents.

• Journal of Korean Academy of Oral Health
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• 제41권4호
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• pp.231-236
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• 2017

Objectives: The objectives of this study were to investigate the changes in bisphenol A (BPA) concentrations in urine from before to after sealant filling and the relationship between BPA and the number of teeth with sealed surfaces. Methods: Thirty-one children aged 6 and 7 years from three elementary schools in Daegu city who did not have any sealant and resin filling were selected as subjects. Urine samples were collected before and after sealant filling until 24 hours, with informed consent from their caregivers. The BPA concentration in all the collected urine samples was analyzed at Seegene Medical. Statistical analysis was performed using the Friedman test, Scheirer-Ray-Hope test, and the repeated-measures generalized linear mixed model of SPSS version 22.0. Results: The BPA concentrations increased from $3.49-{\mu}g/g$ creatinine before to $4.91-{\mu}g/g$ creatinine 2-3 hours later and to $4.15-{\mu}g/g$ creatinine after 24 hours. The more teeth with sealed surfaces, the higher the BPA concentration in children, but the difference was not statistically significant (P>0.05). Conclusions: The BPA concentrations were highest at 2-3 hours after sealant filling and decreased at 24 hours. Exposure to the sealant appears to have a meaningful correlation with the concentration of BPA in the urine of children.

• 실내환경 및 냄새 학회지
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• 제16권2호
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• pp.139-149
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• 2017

In order to reduce odor and methane emission from the landfill, open biocovers and a closed biofilter were applied to the landfill site. Three biocovers and the biofilter are suitable for relatively small-sized landfills with facilities that cannot resource methane into recovery due to small volumes of methane emission. Biocover-1 consists only of the soil of the landfill site while biocover-2 is mixed with the earthworm casts and artificial soil (perlite). The biofilter formed a bio-layer by adding mixed food waste compost as packing material of biocover-2. The removal efficiency decreased over time on biocover-1. However, biocover-2 and the biofilter showed stable odor removal efficiency. The rates of methane removal efficiency were in order of biofilter (94.9%)>, biocover-1(42.3%)>, and biocover-2 (37.0%). The methane removal efficiency over time in biocover-1 was gradually decreased. However, drastic efficiency decline was observed in biocover-2 due to the hardening process. As a result of overturning the surface soil where the hardening process was observed, methane removal efficiency increased again. The biofilter showed stable methane removal efficiency without degradation. The estimate methane oxidation rate in biocover-1 was an average of 10.4%. Biocover-2 showed an efficiency of 46.3% after 25 days of forming biocover. However, due to hardening process efficiency dropped to 4.6%. After overturn of the surface soil, the rate subsequently increased to 17.9%, with an evaluated average of 12.5%.

• Journal of Forest and Environmental Science
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• 제38권2호
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• pp.102-109
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• 2022

This study was conducted to test the significant difference of fertility variation among families and to select superior families for acorn production in the breeding seedling seed orchards (BSSOs) of Quercus acuta and Quercus glauca. The seed orchards were located in Jeju island and established by seedlings raised from selected parents for genetic testing in 2006. In the spring of 2021, the numbers of female and male flower were counted from 5 to 10 individuals per family in the BSSOs. To test statistical significance of which parameter is not satisfied through the normality test, we used a nonparametric analysis. Correlation analysis was performed to quantify the association between female and male flower production. As the results, the significant difference of flower production among families was found in both seed orchards. The averages of female flower production were 65.3 and 181.9 in Q. acuta and Q. glauca. The positive Spearman's rank correlation was existed between male and female flower production. Broad-sense heritability on female and male flower production were 0.191 and 0.147 in Q. acuta, and 0.285 and 0.068 in Q. glauca, respectively. Sexual asymmetry (e.g., maleness index) between female and male, and contribution variation among families (e.g., parental balance) were analyzed to find reasonable alternatives in the management of seed orchards. Effective population size of seed crops was predicted as a concept of status number. Loss of gene diversity (accumulation of group coancestry) would not be alarming in the BSSOs. Our results would be helpful to select breeding materials for establishing new seed orchards and to supply genetically improved seeds of evergreen oaks, which is one of the backbones of the strategy of carbon sink in the 2050 Carbon Neutrality of Korea Forest Service.

• Journal of Veterinary Science
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• 제21권6호
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• pp.81.1-81.10
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• 2020

Background: Although previous in vivo studies explored urinary microRNA (miRNA), there is no agreement on nephrotoxicity-specific miRNA biomarkers. Objectives: In this study, we assessed whether urinary miRNAs could be employed as biomarkers for nephrotoxicity. Methods: For this, literature-based candidate miRNAs were identified by reviewing the previous studies. Female Sprague-Dawley rats received subcutaneous injections of a single dose or repeated doses (3 consecutive days) of gentamicin (GEN; 137 or 412 mg/kg). The expression of miRNAs was analyzed by real-time reverse transcription-polymerase chain reaction in 16 h pooled urine from GEN-treated rats. Results: GEN-induced acute kidney injury was confirmed by the presence of tubular necrosis. We identified let-7g-5p, miR-21-3p, 26b-3p, 192-5p, and 378a-3p significantly upregulated in the urine of GEN-treated rats with the appearance of the necrosis in proximal tubules. Specifically, miR-26-3p, 192-5p, and 378a-3p with highly expressed levels in urine of rats with GEN-induced acute tubular injury were considered to have sensitivities comparable to clinical biomarkers, such as blood urea nitrogen, serum creatinine, and urinary kidney injury molecule protein. Conclusions: These results indicated the potential involvement of urinary miRNAs in chemical-induced nephrotoxicity, suggesting that certain miRNAs could serve as biomarkers for acute nephrotoxicity.

• 대한치과마취과학회지
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• 제12권2호
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• pp.93-97
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• 2012

Background: Some disabled patients show insufficient cooperation during dental treatment, and general anesthesia in an outpatient setting can be successfully administered. To minimize post-anesthetic complications is an essential issue, and strict discharge protocols are required for the safety of the patients. Post-anesthetic follow-ups using telephone calls can be applied to improve the quality of the outpatient care system. The authors evaluated the post-operative condition of patients after dental treatment under general anesthesia. Methods: Total 143 patients and their caregivers included in this study. The patients received general anesthesia for dental treatment in Seoul National University Dental Hospital, Clinic for Persons with Disabilities from July, 2011 to April, 2012. Telephone calls were given to the patients or their caregivers to collect information about the patients' systemic condition and anesthesia-related complications. Results: Among 131 patients with responses of telephone calls, 87 patients (66.4%) reported no discomfort, while 44 patients (33.6%) presented post-anesthetic complications. A total of 20 patients reported mild fever, 10 patients had vomiting, and 7 patients had sore throat. Other complications included nausea, fatigue, nasal bleeding, skin sore, and body rash. Among the patients with the history of epilepsy, 63.6% showed post-anesthetic discomfort or complication (P = 0.027, ${\chi}^2$ test). Conclusions: One third of dental patients who received general anesthesia due to insufficientcooperation complained discomfort after discharged from outpatient anesthetic care.

• Biomolecules & Therapeutics
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• 제25권4호
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• pp.374-382
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• 2017

Autism spectrum disorder (ASD) remains unexplained and untreated despite the high attention of research in recent years. Aside from its various characteristics is the baffling male preponderance over the female population. Using a validated animal model of ASD which is the telomerase reverse transcriptase overexpressing mice (TERT-tg), we conducted ASD-related behavioral assessments and protein expression experiments to mark the difference between male and females of this animal model. After statistically analyzing the results, we found significant effects of TERT overexpression in sociability, social novelty preference, anxiety, nest building, and electroseizure threshold in the males but not their female littermates. Along these differences are the male-specific increased expressions of postsynaptic proteins which are the NMDA and AMPA receptors in the prefrontal cortex. The vGluT1 presynaptic proteins, but not GAD, were upregulated in both sexes of TERT-tg mice, although it is more significantly pronounced in the male group. Here, we confirmed that the behavioral effect of TERT overexpression in mice was male-specific, suggesting that the aberration of this gene and its downstream pathways preferentially affect the functional development of the male brain, consistent with the male preponderance in ASD.

• 식물분류학회지
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• 제49권1호
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• pp.70-89
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• 2019

경기도 용인시에 위치하는 정광산의 관속식물상을 조사하고 이에 분포하는 주요식물을 확인하였다. 본 조사는 2015년 5월부터 2016년 9월까지 총 14회에 걸쳐 이루어졌으며, 조사 결과 정광산에서 총 89과 234속 323종 6아종 34변종 4품종의 367분류군의 관속식물 분포가 확인되었다. 이 중 한국특산식물은 8분류군이 확인되었고, 식물구계학적 특정식물은 IV등급 4분류군, III등급 4분류군, II등급 2분류군, I등급 9분류군으로 총 19분류군이 확인되었다. 국외반출 승인대상 식물은 59분류군이 확인되었다. 적색목록 식물로는 준위협종(Near Threatened, NT)으로 께묵 1분류군, 관심대상종(Least Concern, LC)으로 금붓꽃 1분류군으로 총 2분류군이 확인되었다. 귀화식물로는 개망초, 돼지풀, 붉은서나물 등을 포함하여 27분류군이 확인되었다.

• 식물분류학회지
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• 제51권1호
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• pp.49-99
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• 2021

광덕산은 충청남도 천안시와 아산시의 경계에 위치한, 이 일대에서는 가장 높은 산이다. 본 연구에서는 2015년 4월부터 2017년 10월까지 총 20회에 걸쳐 광덕산의 관속식물상을 조사하여, 97과 287속 428종 9아종 30변종 1품종의 총 468분류군을 확인하였다. 이 중 특산식물, 식물구계학적특정식물, 국외반출승인대상종, 희귀식물 및 멸종위기야생식물, 그리고 외래식물 및 생태계교란식물에 해당하는 58과 112속 129분류군이 주요식물로 조사되었다. 광덕산의 식물상은 크게 남동방면, 남서방면, 북방면, 정상부의 4개 구역으로 구분되었으며, 각 구역별로 분포하는 식물상이 뚜렷이 구분되었다. 광덕산의 식물상에 대한 본 조사 결과와 이전의 조사 결과를 종합하여 볼 때, 광덕산은 식물구계학적으로 중요한 의미가 있다고 생각되어 보전 및 연구가치가 큰 것으로 판단된다.

• 동의생리병리학회지
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• 제22권2호
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• pp.267-276
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• 2008

According to a treatment of internal disease in oriental medicine, we recognize that Lee Dong-won's Eumhwalon has a critical meaning. However, there is no well organized study about that so far even though medical treatments and prescriptions affected by Lee Dong-won's Eumhwalon have been used in clinical medicine. Hence I have studied the effect on a treatment of internal disease of after age affected by Lee Dong-won's Eumhwalon focused on medical treatments and prescriptions. For the comprehensive study on the effect of Lee Dong-won’s(李東垣) Eumwhalon(陰火論) on a treatment of internal disease for after age, I have examined, collected, and summarized the related descriptions from various books and papers in this subject such as <Naek-yung(內經)> which is the bible of oriental medicine. Followings are obtained as a result: Lee dong-won said Eumhwa(陰火) might be happened if there are abnormalities of the spleen and the stomach which exercise going up and coming down(升降). Lee dong-won offered Gamonjeyol(甘溫除熱) and Sengyangsanwha(升陽散火) as treatments of Eumhwa(陰火) Gamonjeyol(甘溫除熱) affected the treatment and the pathological recognition of Daekilon(大氣論) by Jang suk-sun(張錫純). Consequently there are some prescriptions such as Sengham-tang(升陷湯), Wandae-tang(完帶湯), Kerwonjern(擧元煎), and so on affected by Gamonjeyol(甘溫除熱). Sengyangsanwha(升陽散火) affected Yuklumanju(逆流挽舟) by Yu chang(喩昌) a lot. It is a meaning of Sengyangsanwha(升陽散火) that he used Insampaedok-san(人蔘敗毒散) to dysentery. As a representative prescription, there are Insampaedok-san(人蔘敗毒散), Kamisoyo-san(加味逍遙散), Baekchuljakyak-san(白朮芍藥散), and so on.