• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.23 no.2
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• pp.69-80
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• 2010

Objective : The purpose of this study was to compare anti-Inflammation and anti-oxidation of Jeondo-San(JDS) extracted with two kinds of solvents, ethanol and water. Methods : Two kinds of JDS extractions were prepared 20, 50, $100\;{\mu}g/mg$. The Cytotoxicity was measured by MTT assay in Raw 264.7 cell. The anti-inflammation effects were measured by inhibitory efficacy on $PGE_2$, NO, TNF-$\alpha$, COX-2 and iNOS in Raw 264.7 cell. The anti-oxidation effects were measured by ROS inhibitory efficacy, intracellular GSH synthesis and DPPH Radical scavenging in HaCaT cell. Results : 1. All of JDS extraction groups had no cytotoxicity in Raw 264.7 cell. 2. All of JDS extraction groups showed significantly inhibitory effect on production of $PGE_2$. Inhibitory efficacy increased in accodance with concentration. 3. All of JDS extraction groups showed significantly inhibitory effect on production of NO. Inhibitory efficacy increased in accodance with concentration. 4. All of JDS extraction groups did not show significantly inhibitory effect on production of TNF-$\alpha$. 5. $100\;{\mu}g/ml$ JDS extracted with ethanol and $50\;{\mu}g/ml$, $100\;{\mu}g/ml$ JDS extracted with water showed inhibitory effect on iNOS expression. 6. All of JDS extraction groups showed significantly inhibitory effect on production of ROS. Inhibitory efficacy increased in accodance with concentration. Ethanol extractions were better than water extractions. 7. $100\;{\mu}g/ml$ JDS extracted with ethanol only produced GSH of $32{\pm}5.2%$. 8. All of JDS extraction groups showed significantly scavenging effect of DPPH radicals. Inhibitory efficacy increased in accodance with concentration. Ethanol extractions were better than water extractions. Conclusion : Two kinds of JDS extractions have not cytotoxicity and inhibit production of NO. JDS extracted with water was effective in anti-inflammation, JDS extracted with ethanol was effective in anti-oxidation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.2 s.33
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• pp.89-101
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• 2007

Objectives : This study was carried out to investigate the effects of Jeondo-San(JDS) on anti-Inflammation and anti-Propionibacterium acnes. Methods : The effects of JDS on anti-Inflammation and anti-Propionibacterium acnes were measured by the cytotoxicity of Raw 264.7 cell, the inhibition for NO, $TNF-{\alpha}$, $PGE_2$, iNOS and COX-2, the blocking $NF-{\kappa}B$ into nucleus and the sterilizing power for Propionibacterium acnes. Results : 1. All concentrations of JDS has no cytotoxicity in Raw 264.7 cell. 2. All concentrations of JDS inhibited the production of NO in the Raw 264.7 cell stimulated with LPS. 3. All concentrations of JDS did not significantly inhibit the production of $TNF-{\alpha}$ in the Raw 264.7 cell stimulated with LPS. 4. All concentrations of JDS inhibited the production of $PGE_2$ in the Raw 264.7 cell stimulated with LPS. 5. All concentrations of JDS did not inhibit the expression of COX-2 but concentrations of 50\;{\mu}g/ml$, 100\;{\mu}g/ml$ JDS inhibited iNOS expression in the Raw 264.7 cell stimulated with LPS. 6. Concentrations of 50\;{\mu}g/ml$, 100\;{\mu}g/ml$ JDS has the effect of blocking $NF-{\kappa}B$ into nucleus in LPS-induced macrophage Raw 264.7 cell. 7. All concentrations of IDS did not have the inhibitory effect of Propionibactrium acnes. Conclusions : The present date suggest that JDS has a effect on the stage of inflammation of acne.

• Journal of Pharmacopuncture
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• v.11 no.1
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• pp.143-147
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• 2008

Objectives : This study was carried out to investigate the antioxidant effects of Jeondo-san(JDS). Methods : The antioxidant effects of JDS were measured by the scavenging for 2,2-Diphenyl-1-picrylhydrazyl(DPPH) radical, the formation of intracellular glutathione(GSH), the inhibition for reactive oxygen species(ROS). Results : 1. All concentrations of JDS showed antioxidant effect by decreasing the DPPH radicals. 2. All concentrations of JDS did not effect on the formation of intracellular GSH in HaCaT cell. 3. All Concentrations of JDS inhibited the production of ROS in the HaCaT cell stimulated with $H_2O_2$. Conclusion : The present date suggest that JDS has effects on the stage of inflammation.

• Journal of Distribution Science
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• v.20 no.3
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• pp.59-69
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• 2022

Purpose: The purpose of this study is to provide information for other journals as well as the continuous development of distribution science research by confirming the globalization performance of the Journal of Distribution Science (JDS), the main journal of KODISA. Research Design, Data, and Methodology: A total of 863 papers published in JDS from 2011 to 2021 searched by scienceON were divided into 4 periods and analyzed under the headings of submission system, standardity, collaboration, and degree of achievement of publication goals. SPSS 24.0 and R 4.1.1 package were used to perform the publication frequency analysis, crosstab-analysis, keyword frequency analysis, and LDA topic modeling were performed. In addition, trend analysis with weight applied to each word was performed. Results: It was found that the ratio of English-written papers, which is the indicator of a journal's starndardity, is continuously increasing, and the ratio of overseas authors, which is the indicator of collaboration, is also continuously increasing. It was confirmed through keyword trend analysis by period and LDA topic modeling results - which were weighted to confirm the degree of achievement of the journal's publication goal - that the articles published by the journal has been in agreement with monthly research topic proposed by JDS. Conclusion: By examining the five criteria for globalization, it can be concluded that JDS's efforts for globalization are achieving significant results and providing effective directions for other academic journals. However, in order for JDS to become a top academic journal, it was suggested that efforts should be made to establish a system for collaborative research by domestic and foreign authors, as well as to provide a clear definition for the monthly research topics and classification of sub-topics.

• Research in Plant Disease
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• v.28 no.3
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• pp.122-131
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• 2022

Colletotrichum acutatum s. lat. 20JDS8 sensitive and 20CDJ6 resistant to pylaclostrobin were used to investigate the cross-resistance with fungicides belonging to the strobilurins and the characteristics of fungicidal controlling activities with different mechanisms against the isolate resistant to the fungicide. The resistant isolate of 20CDJ6 also showed the resistance to azoxystrobin, trifloxystrobin, and kresoxim-methyl, suggesting that there is a cross-resistance relationship. All fungicides with different action mechanisms inhibited mycelial growth of both susceptible and resistant isolates of C. acutatum s. lat., but their disease control effects in fruits were different according to the fungicides. The disease control effect of isopyrazam against 20JDS8 and 20CDJ6 was very low, and fluazinam showed a control effect of 91.9% and 88.1% against 20JDS8 and 20CDJ6 only when it was treated before inoculation by spraying spore suspensions on pepper fruits without wounds. Tebuconazole and prochloraz effectively inhibited not only the mycelial growth of 20JDS8 and 20CDJ6 on potato dextrose agar medium, but also disease incidence in red pepper fruits. As a result of this study, C. acutatum s. lat. 20CDJ6 resistant to pyraclostrobin showed cross-resistance with other strobilurin fungicides. In addition, we think that fluazinam, tebuconazole, and prochloraz can be recommended as alternative fungicides for the control of red-pepper pyranthracnose pathogens resistant pyraclostrobin. However, fluazinam can be effective only if it is treated protectively before the occurrence of the disease.

• The Journal of Industrial Distribution & Business
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• v.10 no.8
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• pp.17-24
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• 2019

Purpose - The purpose of this study is to find out research directions for distribution and fusion and complex field to many domestic and foreign researchers carrying out related academic research by confirming research trends in the Journal of Distribution Science (JDS). Research Design, Data, and Methodology - To do this, I used keywords from a total of 904 papers published in the JDS excluding 19 papers that were not presented with keywords among 923. The analysis utilized word clouding, topic modeling, and weighted frequency analysis using the R program. Results - As a result of word clouding analysis, customer satisfaction was the most utilized keyword. Topic modeling results were divided into ten topics such as distribution channels, communication, supply chain, brand, business, customer, comparative study, performance, KODISA journal, and trade. It is confirmed that only the service quality part is increased in the weighted frequency analysis result of applying to the year group. Conclusion - The results of this study confirm that the JDS has developed into various convergence and integration researches from the past studies limited to the field of distribution. However, JDS's identity is based on distribution. Therefore, it is also necessary to establish identity continuously through special editions of fields related to distribution.

• Journal of Distribution Science
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• v.13 no.3
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• pp.5-9
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• 2015

Purpose -The purpose of this study was to review and analyze the four major journals of KODISA and all of their published articles of 2014 and to revise and update the existing publication standards and practices in order to improve the overall quality and reputation of these journals. Research design, data, and methodology - This study applied an analytical approach, a case study method, to analyze and examine the published articles and the publication standards and practices of four KODISA journals, JDS (1999), IJIDB (2010), EAJBM (2011), and JAFEB (2014), from their first publication. Results - In 2014, KODISA journals published a total of 171 papers - JDS (122), IJIDB and EAJBM (16 each), and JAFEB (17): 94 articles in general business and 77 articles in economics. Conclusions - KODISA journals continuously revised and updated their publication standards and practices and adopted technological support systems to enable its journals to remain independent and open access in order to ultimately become one of the world's reputable journals.

• The Journal of Korean Medicine
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• v.34 no.3
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• pp.106-118
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• 2013

Objectives: The aim of this study was to evaluate the effect of a mild cognitive impairment (MCI) management program on traditional Korean medicine in a public health center. Methods: In order to examine the effect of the MCI management program, we investigated MCI patients who participated in the program. MCI patients were treated with Jodeung-san (JDS) or Dangguijagyag-san (DGJYS) for 6 weeks. Mini Mental State Examination-Dementia Screening (MMSE-DS), Geriatric Quality of Life-Dementia (GQOL-D), Geriatric Depression Scale in Korea (GDS-K), and biochemical examination of blood were conducted at intervals of 6 weeks. A satisfaction survey was collected after this program. Results: MMSE-DS mean score increased significantly, by 4.09 (p=0.000) in the JDS group and by 4.15 (p=0.000) in the DGJYS group. GQOL-D mean score also increased significantly, by 5.90 (p=0.000) in the JDS group and by 5.07 (p=0.000) in the DGJYS group. GDS-K mean score decreased significantly, by 10.63 (p=0.000) in the JDS group and by 9.69 (p=0.000) in the DGJYS group. MMSE-DS, GDS-K and GQOL-D scores were not significantly different between the JDS and DGJYS groups. All of the participants were satisfied with the program, and 90% of the participants expressed a high intention to participate in the program again. Conclusions: Both Jodeung-san and Dangguijagyag-san treatment showed improvement on cognitive function, depression and quality of life in this program. Additional studies with more subjects will be required to prove credibility and validity more clearly.

• The Journal of Korean Medicine
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• v.26 no.3 s.63
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• pp.74-79
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• 2005

Objectives : The purpose of This study was to find the effect of Jeondo-gan (JDS) on acne. Methods : From December 1, 2003 to January 31, 2004, 11 patients with acne were observed, limited to patients who were teated with JDS for more than three weeks. JDS mined with cold water was used on outbreaks of acne, 15 minutes. 1 time per night, 6 times per week. Results & Conclusions : 3 males and 8 females were treated ever three weeks, The average age was 21.73 years old. Before treatment, ache patients had sparse papules on the forehead. both cheeks, and chin, After treatment over three weeks, nine acne patients changed for ihe better at a rate of $81.8\%$ (mild improved $54.6\%$, improved $18.2\%$, much improved $9\%$)

• Journal of Distribution Science
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• v.15 no.5
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• pp.75-83
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• 2017

Purpose - With the rise of the fourth industrial revolution, it has converged with the existing industrial revolution to give shape to increased accessibility of knowledge and information. As a result, it has become easier for scholars to actively persue and compile research in various fields. This current study aims to focus and assess the current standing of KODISA: the Journal of Distribution Science (JDS), International Journal of Industrial Distribution & Business(IJIDB), the East Asian Journal of Business Management (EAJBM), the Journal of Asian Finance, Economics and Business (JAFEB) in a rapidly evolving era. Novel strategies for creating the future vision of KODISA 2020 will also be examined. Research design, data, and methodology - The current research will analyze published journals of KODISA in order to offer a vision for the KODISA 2020 future. In part 1, this paper will observe the current address of the KODISA journal and its overview of past achievements. Next, part 2 will discuss the activities that will be needed for journals of KODISA, JDS, IJIDB, EAJBM, JAFEB to branch out internationally and significant journals will be statistically analyzed in part 3. The last part 4 will offer strategies for the continued growth of KODISA and visions for KODISA 2020. Results - Among the KODISA publications, IJIDB was second, JDS was 23rd (in economic publications of 54 journals), and EAJBM was 22nd (out of 79 publications in management field journals). This shows the high quality of the KODISA publication journals. According to 2016 publication analysis, JDS, IJIDB, etc. each had 157 publications, 15 publications, 16 publications, and 28 publications. In the case of JDS, it showed an increase of 14% compared to last year. Additionally, JAFEB showed a significant increase of 68%. This shows that compared to other journals, it had a higher rate of paper submission. IJIDB and EAJBM did not show any significant increases. In JDS, it showed many studies related to the distribution, management of distribution, and consumer behavior. In order to increase the status of the KODISA journal to a SCI status, many more international conferences will open to increase its international recognition levels. Second, the systematic functions of the journal will be developed further to increase its stability. Third, future graduate schools will open to foster future potential leaders in this field and build a platform for innovators and leaders. Conclusions - In KODISA, JDS was first published in 1999, and has been registered in SCOPUS February 2017. Other sister publications within the KODISA are preparing for SCOPUS registration as well. KODISA journals will prepare to be an innovative journal for 2020 and the future beyond.