• The Journal of Korean Physical Therapy
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• 제21권3호
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• pp.17-24
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• 2009

Purpose: The purpose of this study was to investigate the effects of a combination of isotonic (CI) technique on the balance, muscle fatigue and muscle activities of the quadriceps muscle in the paretic leg of hemiplegic patients. Method: All the subjects received a combined isotonic technique of proprioceptive neuromuscular facilitation (PNF) for about 30 minutes 3 times per week for 6 weeks. The root mean square (RMS) and mid frequency (MF) were recorded by surface electromyography (EMG)(EMG/EP system, OXFORD Medelec, UK) during maximal voluntary isometric contractions (MVIC). The balance ability was measured by a balance system (BIODEX, USA). Result: The RMS of the quadriceps muscle at post-treatment was significantly increased compared to that at pretreatment (p<0.05). Yet there was no significant difference among the three muscles. There were no significant difference in the MF of the vastus lateralis and rectus femoris between pre- and post-treatment, but the MF of the vastus medialis was significantly decreased (p<0.05). There was a significant difference in the vastus medialis and lateralis between pre- and post-treatment (p<0.05). Moreover, the overall stability index at post-treatment was significantly decreased compared to that at pre-treatment (p<0.05). But there was no significant difference between the anterior/posterior and medial/lateral stability indexes. Conclusion: The results of this study indicated that a CI technique of PNF had an effect to improve the balance and muscle activity in hemiplegic patients.

• 대한임상검사과학회지
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• 제36권2호
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• pp.127-130
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• 2004

Analytical sensitivity on TDM test is the lowest concentration that can be distinguished from background noise. The aim of study was to evaluate analytical sensitivity that is also referred to as the lower limit of detection(LLD) about difference between zero calibrator and isotonic saline sample. We tested for 10 days with zero calibrators and 0.85% saline samples while running trilevel control samples under control. Raw data divided by two groups calculated mean and standard deviation from two sample populations and analytical sensitivity by ${\bar{X}}+2SD$. In comparison with isotonic saline samples and zero calibrators, there were significant differences in phenytoin, phenobarbital and vancomycin, etc. Especially analytical sensitivity on phenytoin is at the same level as the upper limit of analytical measurement range with $40{\mu}g/mL$. We think the cause of this is matrix interference. In conclusion, we were sure that standard protocol for analytical sensitivity as lower limit of analytical measurement range on TDM test must be measured with zero standard rather than an isotonic saline sample and type 1 reagent DW for reducing matrix effects within interactions between different materials in a mixture.

• PNF and Movement
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• 제5권2호
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• pp.37-46
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• 2007

Purpose : The purpose of this study was to examine the effects of combination of isotonic and rhythmic stabilization in proprioceptive neuromuscular facilitation on trunk stability and balance in elderly people with chronic low back pain. Subjects : Thirty-two elderly people ($73.78{\pm}8.49$ years of age) who had complaints of CLBP were randomly assigned to 2 groups: experimental group and control group. Methods : Subject trained with combination of isotonic and rhythmic stabilization in proprioceptive neuromuscular facilitation for 4weeks with aim of improving trunk stability and balance. Weight distribution, trunk muscle balance, static balance ability and dynamic balance ability were measured before, at the end of training. Results : Data were analyzed using two-way ANOVA. After the exercise programs, there were significant differences in the weight distribution, trunk muscle balance and dynamic balance ability between the experimental and control group. However there was no significant difference in the one leg stance test(p<.05). Conclusion : This study suggest that PNF programs may be appropriate for improving trunk stability and balance in elderly people with CLBP.

• 한국식품영양과학회지
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• 제31권3호
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• pp.399-404
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• 2002

박테리오신 생성 젖산균을 이용하여 과실채소 혼합발효액을 제조하고, 발효액의 이화학적 특성과 항균특성을 조사하여 항균 이온음료로서의 가능성을 고찰하였다. 박테리오신 생성 젖산균을 이용한 발효시 발효종균으로 Leu. mesenteroides와 Lc. lactis ATCC l1454를 동시 접종하였을때는박테리오신이 생성되지 않았으며, Leu mesenteroides에 의한 젖산발효 후에 pH를 조정하고 박테리오신 생성균을 접종하였을 때 적정량의 산과 항균물질이 생성되었다. 발효액의 당함량과 무기염류를 분석한 결과, 발효액에는 시판되고 있는 이온음료에 비해 Na과 P의 함량은 높은 편이나, K,Ca, Mg 등의 농도 차이는 크지 않은 것으로 나타났으며, 당함량도 약간 낮은 것으로 나타났다. 발효액은 충치 원인균인 Streptococcus mutans에 대한 안정된 항균효과를 지니고 있으며, 발효액의 색상은 저장 중에도 안정된 것으로 나타났다. 따라서 과실채소 혼합발효액의 무기질 발란스와 기호도를 고려한 당농도 조절 등의 보완이 이루어진다면 우리고유의 이온음료로 개발 가능성이 있다고 판단된다.

• PNF and Movement
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• 제16권3호
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• pp.333-343
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• 2018

Purpose: The purpose of this study was to investigate the effects of a neck exercise using a proprioceptive neuromuscular facilitation (PNF) neck flexion and extension pattern on body balance in a progressive range of positions (supine, prone on elbow, and sitting), on numbness in the upper extremities, and on neck flexion motions in cervical myelopathy patients. Methods: One participant who was diagnosed with cervical myelopathy participated in this study. A reversal design (A-B-A') was used. The A and A' were the baseline period (no intervention), and B was the intervention period. The intervention used a neck extension pattern with a hold-relax technique and a neck flexion pattern with a combination of isotonic techniques in the supine position. Then, neck flexion and extension patterns were applied together with a reversal technique for stabilization, followed by a neck extension pattern with a combination of isotonic techniques in the prone position on the elbows. Finally, a neck flexion and extension pattern was used with a stabilizing reversal technique, and a neck extension pattern was applied with a combination of isotonic techniques in the sitting position for 60 minutes per day, 3 times per week for 8 weeks. To measure balance, numbness, and neck motion during neck flexion, the one-leg stand test and the visual analogue scale were used. Results: The right and left one-leg stand tests showed increased balance ability in the intervention phase. Upper extremity numbness was decreased in the intervention phase, and neck flexion motion was increased in the intervention phase. These increases were maintained after the intervention (Baseline II). Conclusion: These results suggest that a neck exercise using a PNF neck pattern with additional techniques in a progressive range of positions has a positive effect on cervical myelopathy patients for balance, numbness, and neck motion.

• 대한수의학회지
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• 제36권2호
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• pp.305-312
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• 1996

Cell volume regulatory mechanisms are usually disclosed by exposure of cell to anisotonic media. If a cell is suddenly exposed to hypotonic media, it swells initially like an osmometer but within minutes regains its original cell volume. This behavior has been labelled as regulatory cell volume decrease(RVD). RVD is believed to result from the loss of permeable ions through the membrane. In this study, we examined hypotonically induced changes in the membrance currents involved in RVD by using whole cell voltage clamp technique in the unfertilized hamster egg. At -40mV of the holding potential, the stationary current was maintained in the hamster egg exposed to isotonic solution composed of, mainly, 115mM NaCl and 40mM mannitol. Hypotonic solution was prepared by removing mannitol. Therefore, the concentrations of $Na^+$ and $Cl^-$ in this hypotonic media were the same as those in the isotonic solution. Following 30 to 60 sec after applying the hypotonic media to the egg, the inward current was evoked. This inward current was eliminated by $100{\mu}M$ 4-acetamido-4'-isothiocyanostil-bene-2,2'-disulfonic acid(SITS), an anion channel blocker, leaving the small outward current component. Further addition of 2mM $Ba^{2+}$, a broad $K^+$ channel blocker, completely abolished the small outward current left even in the presence of SITS during hypotonic stress. These results suggest that $K^+$ and $Cl^-$ move out of cells, resulting in RVD. To test the involvement of $Na^+$ in RVD, 20mM Na-isethionate was substituted for mannitol in isotonic media(135mM $Na^+$) and Na-isethionate (20mM) was freed the hypotonic solution. Only $Cl^-$ concentration in both isotonic and hypotonic media was kept constant at 115mM, whereas concentration of $Na^+$ was lowered in hypotonic solution to 115mM from 135mM in isotonic solution. Hypotonic medium induced the outward current in the egg equilibrated isotonically. This current was reduced by $100{\mu}M$ SITS but was augmented by 2 mM $Ba^{2+}$. In terms of RVD, these results imply that $Cl^-$ efflux is coupled with $K^+$, maybe for electroneutrality during hypotonic stress and/or with $Na^+$ via unknown transport mechanism(s). From the overall results, the hypotonic stress facilitates the movement of $Cl^-$ and $K^+$ out of the hamster egg to regain cellular volume with electroneutrality. If there exist a difference in $[Na^+]_0$ between isotonic and hypotonic solution, another transport mechanism concerned with $Na^+$ may, at least partly, participate in regulatory volume decrease.

• 한국정보전자통신기술학회논문지
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• 제13권3호
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• pp.212-218
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• 2020

인체에 고주파 에너지를 가하면 진동 폭이 매우 짧아서 직류 전류 이용 시 발생하는 전해질 화상이 일어나지 않으며 이온분자, 분극분자 등이 초당 4만 번 이상 진동을 하면서 마찰열로 전환되어 심부열을 발생시켜 모세혈관의 혈류량은 휴식 시 보다 4~5배 증가하여 산소, 영양물질, 항체, 백혈구 등 공급의 증가한다. 또한 진동 폭과 맥동기간이 매우 짧아 전기 화학적 반응이 일어나지 않으며 감각신경과 운동신경을 자극하지 않는 물리적 인자치료 방법이다. 본 연구에서는 고주파통증치료기를 사용하여 젊은 정상 성인을 대상으로 등장성운동을 시키고, 등장성 운동 시 근전도 데이터를 측정하여 운동신경 응답의 변화에 미치는 영향을 확인하여 재활치료 접목시키고자 하였다. 윗팔두갈래근의 등장성 운동을 실시할 때 발생되는 근전도 데이터와 운동 후 고주파통증치료기사용 후 측정된 근전도 데이터를 각각 RMS하여 t-검정을 통하여 검증을 실시하였으며, 남녀 모두 t값, p값이 유의수준(<.05) 보다 작게 나와 유의한 차이가 있다는 것을 확인하였다.

• 한국정보전자통신기술학회논문지
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• 제8권2호
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• pp.178-186
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• 2015

근지구력시간은 근피로를 평가하는 매우 중요한 지시자이다. 근지구력 시간을 직접 측정할 경우 근골격계 손상의 위험이 있다. 따라서 본 연구에서는 근지구력시간을 개인요소와 신체측정치수의 간접측정으로 예측할 수 있는 모델을 제시하려고 한다. 초기에는 개인요소인 성칭과 연령이 근지구력시간의 예측에 상관없다는 결과가 있었지만, 최근에는 팔의 중력토크(GTA, gravitational torque of the horizon arm, stretched arm)와 최대자율수축강도(MVC, maximum voluntary contraction) 등을 독립변수 또는 예측변수로 적용하여 근지구력시간을 예측하였다. 본 연구에서는 등장성 운동 시 개인요소와 신체측정치수를 이용하여 근지구력시간을 예측할 수 있는 변인들에 관하여 연구하였다. 총 25명의 피검자가 자원하여 10%,20%,30%,40% 그리고 50%MVC 강도의 등장성 운동을 수행하였다. 그 후 회귀분석을 통해 산출된 상관계수를 비교하였으며, 그 결과 다중회귀모델에서 유의성 있는 상관계수가 있었으며 근지구력시간을 예측하는 변인으로써 유용함을 알 수 있었다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2012년도 춘계학술대회 논문집
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• pp.751-752
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• 2012

• Journal of the Korean Statistical Society
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• 제25권3호
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• pp.381-391
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• 1996

In the analysis of contingency table with ordered categories, the relationship between odds for adjacent categories has received con-siderable interest. We consider likelihood ratio tests of independence against an order restriction on odds in 2 $\times$ k contingency tables.