• Title/Summary/Keyword: Irregular Frequency

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대명석곡추출물이 Loperamide로 유도된 변비에 미치는 효과 (Effect of Dendrobium speciosum Var. Aqueous Extract on Loperamide-Induced Constipation in Rats)

  • 장지훈;정호경;심미옥;안병관;김민석;강병만;조정희;빈철구;김성철;정원석
    • 한국약용작물학회지
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    • 제24권1호
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    • pp.1-6
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    • 2016
  • Background : Irregular meals and insufficient exercise are major modern lifestyle-related risk factors for constipation. This study aimed to examine the effects of the aqueous extract of Dendrobium speciosum var. (DM) on the improvement of intestinal function and prevention of constipation in rats. Methods and Results : Constipation in rat was induced by loperamide (4 mg/kg) injection for 5 days and rats were randomly assigned to the following groups: normal control rats (NOR), constipated rats (LOP induced) and constipated rats supplemented with dulcolax-S (POS), DMSG, 100 mg/kg (DMSG-100), 300 mg/kg (DMSG-300) and 500 mg/kg (DMSG-500). The DMSG groups showed increments in the frequency and amount of stools compared to the LOP group. Loperamide treatment markedly reduced the water content of feces, whereas DMSG administration significantly increased fecal water contents. Moreover, DMSG improved intestinal transit speed in constipated-rats. Alcian blue staining revealed increased mucus production by crypt cells and mucus contents in feces and the mucosal surface. Conclusions : In summary, DM extraction significantly improves intestinal function in rats, which indicates the effectiveness of this extract in the prevention and treatment of constipation.

유연성 기판을 사용한 광대역 메타 흡수체 (A Broad-Band Metamaterial Absorber Using Flexible Substrate)

  • 이홍민
    • 한국전자파학회논문지
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    • 제25권3호
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    • pp.339-347
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    • 2014
  • 본 논문에서는 유연성 기판을 이용한 새로운 광대역 메타물질 구조의 흡수체를 제안하였다. 제안된 메타 물질 구조의 단위 셀은 유연성 있는 폴리이미드 기판 위의 동일 평면상에 놓여진 ELC 공진기와 cut-wire 구조로 이루어졌으며, 설계 주파수 대역 밖에서 레이더 단면적(RCS) 값을 감소시키기 위하여 제안된 구조의 금속 패턴 층은 입사 전자파의 진행 방향과 평행하게 놓았다. 총 $33{\times}45$개의 단위 셀들의 배열로 이루어진 흡수체 시작품을 제작하고, 측정한 결과, 주파수 9.06 및 15.0 GHz에서 각각 92 % 및 93 % 이상의 최대 흡수율과 75 %의 full-width at half-maximum 대역폭을 나타내었다. 제안된 금속 접지 판이 없는 메타물질 구조는 마이크로파 주파수대 광대역 흡수체로 곡면 구조에도 응용이 가능하다.

Liver Color Scan에 대(對)한 고찰(考察) (Observation of Liver Color Scan)

  • 최용규;안승봉
    • 대한핵의학회지
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    • 제3권2호
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    • pp.55-63
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    • 1969
  • In the past few years, scintigraphy has become increasingly important in clinical practice, and the use of a color-printing technique has permited a more accurate interpretation of the scan image. Our liver color scintigrams consist of 51 hepatomas, 35 liver cirrhosis, 22 liver abscessis, 10 hepatitis and other 13 cases of the liver diseases which were clinically arid pathologically diagnosed at Sevarance Hospital, Yonsei Univ., since Feb. 1969 through Sept. 1969. These scintigrams have been analized in terms of various pathologic morphology, such as size, shape, margin of the liver, distribution of radioactivity, and shape of the space occupying lesions. The results are as follows: 1. Enlargement of the liver was the most common finding in the diseased livers. The Rt. lobe enlargement was particularly prominent in the liver abscess. 2. Irregular distribution of radioactivity in the liver (so called mottling) was present in 78% of hepatoma, while it was seen only in 31% of liver abscesses. 3. Liver cirrhosis tends to show perihilar accumulation of the isotope (57%). 4. The deformity of the lower most angle of the Rt. lobe, and the Lt. lateral margin of the Lt. lobe was also impressive throughout the cases ($74{\sim}95%$ of all diseased livers). 5. The frequency of visualization of the spleen was influenced by the size of space occupying lesions and the amount of functioning liver. 6. Differentiation between the liver abscess and hepatoma seems to be possible on scintigram, when shape and margin of defect and patterns of distribution of radioactivity in the remaining liver are clearly demonstrated.

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중등도 이상 비만아동의 영양소 섭취, 영양지식, 식습관 및 생활태도 조사 (Nutrient Intakes, Nutritional Knowledge, Food Habits, and Lifestyle Behaviors of Obese Children)

  • 최순남;김현정;정남용
    • 대한영양사협회학술지
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    • 제17권4호
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    • pp.349-363
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    • 2011
  • The purpose of this study was to investigate the nutrient intakes, nutritional knowledge, food habits, and lifestyle behaviors of moderately or severely obese children living in the Kyonggi-do area. The subjects in this study were 37 obese children with an obesity index higher than 130% in the forth to sixth grades of elementary school. Anthropometric measurements, 24-hour recall of dietary intakes, and a survey on nutritional knowledge, food habits, and lifestyles behavior were conducted in the 37 obese children (25 boys and 12 girls). The average age, body weight, BMI, and R$\ddot{o}$hrer Index were 12.4 years, 68.6 kg, $29.6kg/m^2$, and 194.9 in boys and 12.7 years, 65.7 kg, $29.8kg/m^2$, and 201.8 in girls, respectively. The percentage of correct answers on nutritional knowledge and nutritional attitude score/max score were 85.8% and 23.0/50 in boys and 87.0% and 17.5/50 in girls, respectively. Except for calcium (85.3%) in girls and calcium (62.7%) and folic acid (83.3%) in boys, the average daily nutrient intakes percentages of nutrients were greater than the DRIs values (107.9~327.3% in boys and 103.0~416.0% in girls). This study showed the existence of some problems associated with obesity, such as higher frequency of skipping breakfast, irregular meal times, unbalanced diet, lack of intake of some nutrients, low nutritional attitude, lack of physical activity, and time management in obese children. These results suggest that a systematic education program including nutritional education on balanced diet, good eating habits and behaviors, and importance of eating breakfast and meal regularity must be emphasized to improve nutrient intakes and food habits in obese children. Obese children also require a more concentrated program that includes physical activity, weight reduction, and weight maintenance strategies to improve their life habits.

뇌졸중 환자 대상 흡인 음성의 음향변수 변동 (Acoustic parameter delta of an aspirated voice in stroke patients)

  • 강영애;지성주;구본석;조철우
    • 말소리와 음성과학
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    • 제9권3호
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    • pp.85-91
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    • 2017
  • The present study aimed to investigate the changes of acoustic parameters of the aspirated voice in stroke patients. The eighty-eight subjects diagnosed with cerebro-vascular accident were divided into 32 penetration/aspiration (P/A) and 56 Non-P/A groups according to the videofluroscopic swallowing study (VFSS) results, and 26 control subjects participated. All subjects preformed VFSS and vowel /a/ was recorded three times pre- and post VFSS. Since the variation in the acoustic parameters within a single phonation has been observed, we proposed a delta formula for the acoustic parameters which can reflect the temporal changes of the each parameter in an utterance. We measured from the voice data eight acoustic parameters: fundamental frequency (F0), standard deviation of F0 (F0_SD), Jitter, relative average perturbation (RAP), Shimmer, amplitude perturbation quotient (APQ), harmonic to noise ration (HNR), noise to harmonic ratio (NHR). Then we found parameters which show the meaningful biggest temporal change in an utterance using the suggested delta parameter. Among them, the deltas of shimmer and APQ were significantly different pre- and post VFSS. These deltas of the P/A and the control group were increased after VFSS, while those of the Non-P/A group was descended. The variation patterns of the P/A and the control group were similar but the change width of the P/A group was larger. The large variations in an aspirated phonation of the P/A group are thought to be caused by irregular changes in air resistance due to residual food on the vocal cords.

A SEARCH FOR AGN INTRA-DAY VARIABILITY WITH KVN

  • LEE, TAESEOK;TRIPPE, SASCHA;OH, JUNGHWAN;BYUN, DO-YOUNG;SOHN, BONG-WON;LEE, SANG-SUNG
    • 천문학회지
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    • 제48권5호
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    • pp.313-323
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    • 2015
  • Active galactic nuclei (AGN) are known for irregular variability on all time scales, down to intra-day variability with relative variations of a few percent within minutes to hours. On such short timescales, unexplored territory, such as the possible existence of a shortest characteristic time scale of activity and the shape of the high frequency end of AGN power spectra, still exists. We present the results of AGN single-dish fast photometry performed with the Korean VLBI Network (KVN). Observations were done in a “anti-correlated” mode using two antennas, with always at least one antenna pointing at the target. This results in an effective time resolution of less than three minutes. We used all four KVN frequencies, 22, 43, 86, and 129 GHz, in order to trace spectral variability, if any. We were able to derive high-quality light curves for 3C 111, 3C 454.3, and BL Lacertae at 22 and 43 GHz, and for 3C 279 at 86 GHz, between May 2012 and April 2013. We performed a detailed statistical analysis in order to assess the levels of variability and the corresponding upper limits. We found upper limits on flux variability ranging from ~1.6% to ~7.6%. The upper limits on the derived brightness temperatures exceed the inverse Compton limit by three to six orders of magnitude. From our results, plus comparison with data obtained by the University of Michigan Radio Astronomy Observatory, we conclude that we have not detected source-intrinsic variability which would have to occur at sub-per cent levels.

정맥용 면역글로불린 투여로 호전된 항-$Di^a$ 항체에 의한 신생아 용혈성 질환 1예 (A Case of Hemolytic Disease of a Newborn by an Anti-$Di^a$ Antibody Treated with Intravenous Immunoglobulin)

  • 이창언;박수진;김원덕
    • Journal of Yeungnam Medical Science
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    • 제30권1호
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    • pp.21-24
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    • 2013
  • Hemolytic disease in a newborn that causes early jaundice is common. It is often due to the Rh (D) and ABO incompatibility, but rarely due to unexpected antibodies. Among these unexpected antibodies, the anti-$Di^a$Dia antibody rarely occurs. The anti-$Di^a$ antibody was observed in the serum and red-cell eluate of an infant, and in the serum of his mother. The frequency of the appearance of the $Di^a$ antigen in the Korean population is estimated to be 6.4-14.5%. This paper reports a case of hemolytic disease in a newborn associated with the anti-$Di^a$ antibody. A full-term male infant was transferred to the authors' hospital due to hyperbilirubinemia the day after his birth. The laboratory data indicated a hemoglobin value of 11.6 g/dL, a reticulocyte count of 10.6%, a total bilirubin count of 14.4 mg/dL, a direct bilirubin count of 0.6 mg/dL, and a positive result in the direct Coombs' test. Due to the identification of an irregular antibody from the maternal serum, an anti-$Di^a$ antibody was detected, which was also found in the eluate made from the infant's blood. The infant had been treated with phototherapy and intravenous immunoglobulin since the second day after his birth and was discharged due to an improved condition without exchange transfusion. Therefore, in cases of iso-immune hemolytic disease in a newborn within 24 hours from birth who had a negative result in an antibody screening test, the conduct of an anti-$Di^a$ antibody identification test is recommended due to the suspicion of an anti-$Di^a$ antigen, followed by early administration of intravenous immunoglobulin.

가구 형태별 여자 노인의 식사 및 건강상태 (Diet and Health Status of Elderly Women According to the Family Type)

  • 최미경;강명화;김미현
    • 대한지역사회영양학회지
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    • 제21권3호
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    • pp.256-264
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    • 2016
  • Objectives: This study aimed to evaluate the diet and health status of elderly women according to the family type. Methods: A total of 307 elderly women participated in this study were divided into one of three groups according to their family type: residing with spouse (RSP; n=88), residing with son or daughter (RSD; n=119), and residing alone (RAL; n=100). Chisquare test was used to assess dietary habits and health status of the subjects by the family types. Results: Results demonstrated significant associations between eating regular meals, person preparing meals, coffee intake, and bone fracture experience and family type. Among the three groups, the RSP and RAL groups had a higher percentage for preparing meals by themselves (p<0.001) than the RSD group. The RAL group had a lower percentage for eating regular meals (p<0.01) but a higher percentage for bone fracture experience (p<0.05) than the other groups. There were no significant differences in monthly allowance, self-estimated health status, physical activity, exercise, drinking, and dietary habits such as frequency of consumption of dairy, beans, eggs, fish, meat, fruits, and vegetables among the three groups. Conclusions: The results showed that elderly women residing alone without a son, daughter, or spouse had more diet-related and health problems such as irregular meals and high bone fracture experience. These findings suggested that elderly women residing alone need more attention and support.

사석방파제의 안정성에 미치는 방향성효과에 관한 실험적 연구 (An Experimental Study on the Stability of Rubble Mound Structures by Wave Directionality)

  • 손병규;류청로
    • 한국해안해양공학회지
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    • 제13권2호
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    • pp.139-148
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    • 2001
  • 파랑에 관계하는 현상에는 월파, 표사이동, 구조물의 진동.동요, 파괴 등 방향성의 영향을 현저하게 받아들이는 것이 많다. 이들은 비선형성이 강하기 때문에 수치계산에 의한 해석이 곤란하므로, 수리모형실험으로 외력인자를 평가, 해석정도를 높일 필요성이 증대하고 있다. 본 연구는 파랑의 다양한 입사각에 따라 사석방파제의 안정성을 논의하였으며, 파괴율은 방향성규칙파에서 $30^{\circ}$, 방향성불규칙파인 경우는 40$^{\circ}$부근에서 입사각 $0^{\circ}$일 때 보다 상대적으로 크게 변동하였다. 즉, 사석방파제의 안정성에 미치는 방향성효과에 따른 것이라고 평가할 수 있다. 이들은 1/10 최대 합성유속의 방향별 빈도분포의 피크가 $20^{\circ}$~$40^{\circ}$에서 발생하는 사실과 부합된다.

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Properties of Spontaneous Activity in Gastric Smooth Muscle

  • Suzuki, H.;Yamamoto, Y.;Hirst, G.D.S.
    • The Korean Journal of Physiology and Pharmacology
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    • 제3권2호
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    • pp.119-125
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    • 1999
  • Mammalian gastric smooth muscles generate spontaneous rhythmic contractions which are associated with slow oscillatory potentials (slow waves) and spike potentials. Spike potentials are blocked by organic $Ca^{2+}-antagonists,$ indicating that these result from the activation of L-type $Ca^{2+}-channel.$ However, the cellular mechanisms underlying the generation of slow wave remain unclear. Slow waves are insensitive to $Ca^{2+}-antagonists$ but are blocked by metabolic inhibitors or low temperature. Recently it has been suggested that Interstitial Cells of Cajal (ICC) serve as pacemaker cells and a slow wave reflects the coordinated behavior of both ICC and smooth muscle cells. Small segments of circular smooth muscle isolated from antrum of the guinea-pig stomach generated two types of electrical events; irregular small amplitude (1 to 7 mV) of transient depolarization and larger amplitude (20 to 30 mV) of slow depolarization (regenerative potential). Transient depolarization occurred irregularly and membrane depolarization increased their frequency. Regenerative potentials were generated rhythmically and appeared to result from summed transient depolarizations. Spike potentials, sensitive to nifedipine, were generated on the peaks of regenerative potentials. Depolarization of the membrane evoked regenerative potentials with long latencies (1 to 2 s). These potentials had long partial refractory periods (15 to 20 s). They were inhibited by low concentrations of caffeine, perhaps reflecting either depletion of $Ca^{2+}$ from SR or inhibition of InsP3 receptors, by buffering $Ca^{2+}$ to low levels with BAPTA or by depleting $Ca^{2+}$ from SR with CPA. They persisted in the presence of $Ca^{2+}-sensitive$ $Cl^--channel$ blockers, niflumic acid and DIDS or $Co^{2+},$ a non selective $Ca^{2+}-channel$ blocker. These results suggest that spontaneous activity of gastric smooth muscle results from $Ca^{2+}$ release from SR, followed by activation of $Ca^{2+}-dependent$ ion channels other than $Cl^-$ channels, with the release of $Ca^{2+}$ from SR being triggered by membrane depolarization.

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