• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.5
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• pp.151-161
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• 2021

Traditional Korean medicine (TKM) takes a holistic view that emphasizes the balance between the elements constituting the human body or between the human body and the external environment. To investigate the holistic properties of TKM, here we propose to apply the methodology of complexity science to the TKM research. Complexity science is a discipline for studying complex systems with interactions between components that raise the behaviour as a whole which can be more than the sum of their parts. We first provide an introduction to the complexity science and its research methods, particularly focusing on network science and data science approaches. Next, we briefly present the current status of TKM research employing these methods. Finally, we provide suggestions for future research elucidating the underlying mechanism of TKM, both in terms of biomedicine and humanities.

• The Korean Journal of Nuclear Medicine
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• v.34 no.1
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• pp.1-9
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• 2000

The rapid progress of molecular genetic methods over the past two decades has necessitated the development of methods to detect and quantify genetic activity within living bodies. Reporter genes provide a rapid and convenient tool to monitor gene expression by yielding a readily measurable phenotype upon expression when introduced into a biological system. Conventional reporter systems, however, are limited in their usefulness for in vivo experiments or human gene therapy because of its invasive nature which requires cell damage before assays can be performed. This offers an unique opportunity for nuclear imaging techniques to develope a novel method for imaging both the location and amount of gene expression noninvasively. Current developments to achieve this goal rely on utilizing either reporter enzymes that accumulate radiolabeled substrates or reporter receptors that bind specific radioligands. This overview includes a brief introduction to the background for such research, a summary of published results, and an outlook for future directions.

• Journal of Preventive Medicine and Public Health
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• v.54 no.3
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• pp.166-172
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• 2021

Traditional epidemiological assessments, which mainly focused on evaluating the statistical association between two major components-the exposure and outcome-have recently evolved to ascertain the in-between process, which can explain the underlying causal pathway. Mediation analysis has emerged as a compelling method to disentangle the complex nature of these pathways. The statistical method of mediation analysis has evolved from simple regression analysis to causal mediation analysis, and each amendment refined the underlying mathematical theory and required assumptions. This short guide will introduce the basic statistical framework and assumptions of both traditional and modern mediation analyses, providing examples conducted with real-world data.

• Journal of Korean Medical classics
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• v.37 no.2
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• pp.1-10
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• 2024

Objectives : The Wenyilun is the first specialized text on warm disease, written by Wuyouke from the Ming period in 1642. Methods : This paper examines the newly discovered manuscript of the Wenyilun called the Yeonreungjip, focusing on its bibliography and content. In addition, the original script of the Yeonreungjip was studied philologically. Results : 1. The Yeonreungjip was transcribed in the early 20th century. 2. The Jongbaegmuusan formula is a tried and tested prescription unique to Korea. 3. The original script of the Yeonreungjip is affiliated with the Chinese Liuchang edition. It is uncertain when this edition was introduced to Korea. 4. The contents of the Yeonreungjip referenced the Siququanshu edition series. Conclusions : In conclusion, the Yeonreungjip is the only transcribed version of the specialized Chinese warm disease text from the Joseon period that is known today. Its implication in the research of warm disease introduction to Korea is manifold.

• Korean Medical Education Review
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• v.19 no.3
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• pp.129-133
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• 2017

Premed education in the college of medicine at the Catholic University of Korea aims to promote student creativity and excellence in accordance with the mission of the college: to have a sense of calling, leadership, and competency. The Catholic Medical College premed curriculum includes 75 credits which are composed of 65 credits for required courses and 10 credits for elective courses. It consists of courses in basic science, medical science, liberal arts and humanities (premedical OMNIBUS). It also involves community programs in 'Vision and Mission,' 'Leadership Training,' and 'Academic Conference.' In addition, students are allowed self-directed choice of their courses and learning for one quarter.

• Tuberculosis and Respiratory Diseases
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• v.80 no.2
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• pp.136-142
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• 2017

Assessing response to therapy allows for prospective end point evaluation in clinical trials and serves as a guide to clinicians for making decisions. Recent prospective and randomized trials suggest the development of imaging techniques and introduction of new anti-cancer drugs. However, the revision of methods, or proposal of new methods to evaluate chemotherapeutic response, is not enough. This paper discusses the characteristics of the Response Evaluation Criteria In Solid Tumor (RECIST) version 1.1 suggested in 2009 and used widely by experts. It also contains information about possible dilemmas arising from the application of response assessment by the latest version of the response evaluation method, or recently introduced chemotherapeutic agents. Further data reveals the problems and limitations caused by applying the existing RECIST criteria to anti-cancer immune therapy, and the application of a new technique, immune related response criteria, for the response assessment of immune therapy. Lastly, the paper includes a newly developing response evaluation method and suggests its developmental direction.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.16 no.2
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• pp.255-260
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• 2003

Introduction: Atopic dermatitis is chronic eczematous recurrent disease of skin and till now its mechanism is not cleary known. It is related to a family history of atopic disease. It has severe itching and it causes eczema secondarily. Atopic dermatitis has mostly severe symptoms and progresses to chronic relapsing. Objectives: The purpose of this study was to estimate the efficacy of herb- medicine treatment on atopic dermatitis. Subjects: 1 treated 5 patients who visited Chungbalsan Kyunghee oriental medical clinic with atopic dermatitis from September, 2001 to October, 2002 partiticipated in the study and were observed for over 2 months. Methods: I treated them with herb-medication and external application. (Atopione)

• Journal of Society of Preventive Korean Medicine
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• v.25 no.3
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• pp.1-14
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• 2021

Objectives : This study aimed to investigate the perception level of Telemedicine among Korean medical doctors. Methods : The on-line survey was administered for Korean Medicine doctors. The survey consisted of 46 questions, addressing issues on concepts and adoption model of Telemedicine. Data were collected from 528 Korean medical doctors, and were analyzed using frequency analysis, t-test, ANOVA, and Kruskalwallis test. Results : The results showed that more than half of respondents had positive attitude towards implementation of Telemedicine in Korean Medicine and conventional medicine areas. Respondents were most positive about the aspect that Telemedicine could reduce 'hospital use by people with disabilities', while they were most concerned about the possibility that patients could be concentrated in large-scale hospitals. As prerequisites for the introduction of Telemedicine, accurate information delivery during remote communication between doctors and patients, clarification of responsibility for Telemedicine at the policy level, and development of equipment for accurate information delivery at the technical level received high responses. Conclusions : Korean Medicine doctors were positive about the implementation of Telemedicine, and they preferred to remote monitoring between doctors and patients. The development of medical equipment for accurate patient information delivery and the establishment of an institutional basis for clarifying responsibilities in case of medical accidents are required.

• Korean Medical Education Review
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• v.14 no.2
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• pp.86-94
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• 2012

This study was conducted to analyze the effects of peer tutoring programs and to introduce the peer tutoring program in medical College. Forty medical students participated in the study and data were collected through surveys and interviews. Through the interviews, we investigated the peer tutoring experiences of tutors and tutees, and what they perceived that they accomplished. Correlation analysis was conducted to investigate the tutoring process variables that affect the academic achievement of tutees. It was found that tutors and tutees reported achievements in the schoolwork, relationships, and emotional aspects.

• Korean Journal of Oriental Medicine
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• v.8 no.2 s.9
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• pp.1-16
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• 2002

${\ulcorner}Gogeumdoseojipseong{\lrcorner}$, it has been compiled by Chenmenglei(1651-1723). This large encyclopedia was published in 1125 during Ohing dynasty of China in the reign of the Kangxi emperor. The medical parts of this encyclopedia was titled the name of Yibuquanlu, but it is not correct. KIOM(Korea Institute of oriental Medicine) researched the compilation and publication of the original book of this and the process of introduction to Chosun with its woodblock-printed book for making database of this book. Even more, we analyzed the structure of this book and apprehended the historical significance about medical interchange between Korea and China by this book. As the result, we found that the most part of this large encyclopedia quotedfrom ${\ulcorner}Donguibogam{\lrcorner}$ of Chosun, then it was back to Chosun and taken a part to medical books such as ${\ulcorner}Imwonkyungjaejis{\lrcorner}$, ${\ulcorner}Uijongsonikr{\lrcorner}$.