• Title/Summary/Keyword: Interval Mapping

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Minimizing a QTL region for intramuscular fat content by characterizing the porcine Phosphodiesterase 4B (PDE4B) gene

  • Kim, Jae-Hwan;Ovilo, Cristina;Park, Eung-Woo;Fernndez, Almudena;Lee, Jun-Heon;Jeon, Jin-Tae;Lee, Jung-Gyu
    • BMB Reports
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    • v.41 no.6
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    • pp.466-471
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    • 2008
  • Three isoforms of pig PDE4B were cloned and classified as two forms: PDE4B1 and PDE4B3, which contain UCR1 and UCR2; and PDE4B2, which contains only UCR2. The amino acid sequences of each isoform showed good conservation in human and rat. PDE4B2 is expressed in a wide range of tissues, but PDE4B1 and PDE4B3 are not. Using an informative SNP for the Iberian x Landrace intercross detected from intron 12, a linkage map was constructed. The location of PDE4B was estimated at 123.6 cM outside of the QTL-CI (124-128 cM) for IMF. However, the QTL-CI for IMF was reconfirmed with high significance, and its position was narrowed down to an interval of 4 cM (the region defined by markers PDE4B and SW1881). Using radiation hybrid mapping, LEPR, LEPROT, DNAJC6, AK3L1 and AK3L2 were selected as positional and/or functional candidates related to the QTL.

Forest Fire Severity Classification Using Probability Density Function and KOMPSAT-3A (확률밀도함수와 KOMPSAT-3A를 활용한 산불피해강도 분류)

  • Lee, Seung-Min;Jeong, Jong-Chul
    • Korean Journal of Remote Sensing
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    • v.35 no.6_4
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    • pp.1341-1350
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    • 2019
  • This research deals with algorithm for forest fire severity classification using multi-temporal KOMPSAT-3A image to mapping forest fire areas. The recent satellite of the KOMPSAT series, KOMPSAT-3A, demonstrates high resolution and multi-spectral imagery with infrared and high resolution electro-optical bands. However, there is a lack of research to classify forest fire severity using KOMPSAT-3A. Therefore, the purpose of this study is to analyze forest fire severity using KOMPSAT-3A images. In addition, this research used pre-fire and post-fire Sentinel-2 with differenced Normalized Burn Ratio (dNBR) to taking for burn severity distribution map. To test the effectiveness of the proposed procedure on April 4, 2019, Gangneung wildfires were considered as a case study. This research used the probability density function for the classification of forest fire damage severity based on R software, a free software environment of statistical computing and graphics. The burn severities were estimated by changing NDVI before and after forest fire. Furthermore, standard deviation of probability density function was used to calculate the size of each class interval. A total of five distribution of forest fire severity were effectively classified.

Identification of QTLs controlling somatic embryogenesis using RI population of cultivar ${\times}$ weedy soybean

  • Choi, Pilson;Mano, Yoshiro;Ishikawa, Atsuko;Odashima, Masashi;Umezawa, Taishi;Fujimura, Tatsuhito;Takahata, Yoshihito;Komatsuda, Takao
    • Plant Biotechnology Reports
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    • v.4 no.1
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    • pp.23-27
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    • 2010
  • Quantitative trait loci (QTLs) controlling ability of somatic embryogenesis were identified in soybean. A frame map with 204-point markers was developed using an RI population consisting of 117 $F_{11}$ lines derived from a cross between cultivar 'Keburi' and a weedy soybean 'Masshokutou Kou 502'. The parents differed greatly in their abilities of somatic embryogenesis using immature cotyledons as explants. The ability of somatic embryogenesis was evaluated in five different experiments: the $F_{11}$ (evaluated in 1998) and $F_{15}$ (2002) generations cultured on basal media supplemented with $40\;mg\;l^{-1}$ 2,4-D (2,4-D1998 and 2,4-D2002), $F_{14}$ (2001) generation on medium with $40\;mg\;l^{-1}$ 2,4-D and high sucrose concentration [2,4-D2001 ($30\;g\;l^{-1}$ sucrose)], and the $F_{11}$ (1998) and $F_{12}$ (1999) generations on medium with $10\;mg\;l^{-1}$ NAA (NAA1998 and NAA1999). The RILs showed wide and continuous variations in each of the five experiments. In the composite interval mapping analysis, 2 QTLs were found in group 8 (D1b + W, LOD = 5.42, $r^2$ = 37.5) in the experiment of 2,4-D1998 and in group 6 (C2, LOD = 6.03, $r^2$ = 26.0) in the experiment of 2,4-D2001 (high concentration sucrose). In both QTLs, alleles of 'Masshokutou Kou 502' with high ability of somatic embryogenesis contributed to the QTLs. For the other three experiments, no QTL was detected in the criteria of LOD >3.0, suggesting the presence of minor genes.

Analysis of the statistical properties for the background fractures in the LILW disposal site of Korea (중.저준위 방사성폐기물 처분 부지 내 배경 단열의 통계적 특성 분석)

  • Ji, Sung-Hoon;Park, Kyung-Woo;Kim, Kyoung-Su;Kim, Chun-Soo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.4
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    • pp.257-263
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    • 2008
  • We analyzed the statistical properties for the conductive background fractures in the Low and Intermediate Level Waste(LILW) disposal site to conceptualize of its groundwater flow system. The background fractures were classified to fracture sets based on their trends and plunges that were obtained from the borehole logging data, and then the fracture transmissivity distribution was inferred from the fixed interval hydraulic test results. The fracture size distribution of each fracture set was estimated using the fracture density and fracture mapping data. To verify the analyzed results, we compared observed field data to simulated one from the DFN model that was constructed with the analyzed statistical properties of the background fractures, and they showed a good agreement.

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Soil Erosion Assessment Using RS/GIS for Watershed Management in Dukchun River Basin, a Tributary of Namgang and Jinyang Lake

  • Cho Byung Jin;Yu Chan
    • Journal of The Korean Society of Agricultural Engineers
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    • v.46 no.7
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    • pp.3-12
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    • 2004
  • The need to predict the rate of soil erosion, both under existing conditions and those expected to occur following soil conservation practice, has been led to the development of various models. In this study Morgan model especially developed for field-sized areas on hill slopes was applied to assess the rate of soil erosion using RS/GIS environment in the Dukchun river basin, one of two tributaries flowing into Jinyang lake. In order to run the model, land cover mapping was made by the supervised classification method with Landsat TM satellite image data, the digital soil map was generated from scanning and screen digitizing from the hard copy of soil maps, digital elevation map (DEM) in order to generate the slope map was made by the digital map (DM) produced by National Geographic Information Institute (NGII). Almost all model parameters were generated to the multiple raster data layers, and the map calculation was made by the raster based GIS software, IL WIS which was developed by ITC, the Netherlands. Model results show that the annual soil loss rates are 5.2, 18.4, 30.3, 58.2 and 60.2 ton/ha/year in forest, paddy fields, built-up area, bare soil, and upland fields respectively. The estimated rates seemed to be high under the normal climatic conditions because of exaggerated land slopes due to DEM generation using 100 m contour interval. However, the results were worthwhile to estimate soil loss in hilly areas and the more precise result could be expected when the more accurate slope data is available.

New Model of Verifiation for Demonstration of Neuronal Basis of Acupuncture by Comparison of Two Different Methods of Acupuncture which Increase Regional Cerebral Blood Flow ( rCBF ) on SPECT (핵의학(SPECT)을 이용한 뇌혈류변화에 대한 침구효과 검증방법의 새로운 모델에 관한 연구)

  • Ahn, Soog-Gi;Kang, Hwa-Jeong;Song, Ho-Chun;Bom, Hee-Seung
    • Journal of Acupuncture Research
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    • v.17 no.2
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    • pp.247-259
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    • 2000
  • Objective : The mechanism of acupuncture to increase cerebral blood flow is still uncertain. The purpose of this study was to evaluate the neural basis of acupuncture by comparing the cerebral regions activated by the stimulation of two different methods of acupunctures at the same acupoint which was suggested by oriental medicine to increase rCBF. Materials and Methods : Thirty-nine healthy volunteers(26 males, 13 females, age $31{\pm}11$ years) were studies by rest/acupuncture Tc-99m ECD brain SPECT using a subtraction method. SPECTs using two methods(needle retention and heated needle with 90% alcohol) at two acupoints (right LI. 4 and ST. 36) were peformed at an interval of three days. For the needle retention method, acupuncture needle was inserted to a depth of about 2 cm into each acupoint 8 minutes after the lst acquisition and continued to retain, and the second injection of Tc-99m ECD was done 15 minutes after the insertion of needle. For the heated acupuncture method, heated needle was inserted in a twinkle within several msec 20 second after the second injection of Tc-99m ECD. The differences of between rest and acupuncture activation state were statistically analyzed using a statistical parametric mapping software. Result : Acupunctures of both methods reveal similar patterns of increase in rCBF. Acupuncture at ST.36 increase rGBF in left anterior temporal, right inferior frontal lobes, and left cerebellum. Acupuncture at LI. 4 increase rCBF in the left frontal cortex, right temporal pole, both inferior frontal cortices and right cerebellum. Conclusion : The effects of two different acupunctures to the same acupoints on rCBF were similar. Therefore, this result suggests Chat the mechanism of acupuncture in the increase of cerebral blood flow have a neural basis.

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Sparse reconstruction of guided wavefield from limited measurements using compressed sensing

  • Qiao, Baijie;Mao, Zhu;Sun, Hao;Chen, Songmao;Chen, Xuefeng
    • Smart Structures and Systems
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    • v.25 no.3
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    • pp.369-384
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    • 2020
  • A wavefield sparse reconstruction technique based on compressed sensing is developed in this work to dramatically reduce the number of measurements. Firstly, a severely underdetermined representation of guided wavefield at a snapshot is established in the spatial domain. Secondly, an optimal compressed sensing model of guided wavefield sparse reconstruction is established based on l1-norm penalty, where a suite of discrete cosine functions is selected as the dictionary to promote the sparsity. The regular, random and jittered undersampling schemes are compared and selected as the undersampling matrix of compressed sensing. Thirdly, a gradient projection method is employed to solve the compressed sensing model of wavefield sparse reconstruction from highly incomplete measurements. Finally, experiments with different excitation frequencies are conducted on an aluminum plate to verify the effectiveness of the proposed sparse reconstruction method, where a scanning laser Doppler vibrometer as the true benchmark is used to measure the original wavefield in a given inspection region. Experiments demonstrate that the missing wavefield data can be accurately reconstructed from less than 12% of the original measurements; The reconstruction accuracy of the jittered undersampling scheme is slightly higher than that of the random undersampling scheme in high probability, but the regular undersampling scheme fails to reconstruct the wavefield image; A quantified mapping relationship between the sparsity ratio and the recovery error over a special interval is established with respect to statistical modeling and analysis.

The history of high intensity rainfall estimation methods in New Zealand and the latest High Intensity Rainfall Design System (HIRDS.V3)

  • Horrell, Graeme;Pearson, Charles
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.16-16
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    • 2011
  • Statistics of extreme rainfall play a vital role in engineering practice from the perspective of mitigation and protection of infrastructure and human life from flooding. While flood frequency assessments, based on river flood flow data are preferred, the analysis of rainfall data is often more convenient due to the finer spatial nature of rainfall recording networks, often with longer records, and potentially more easily transferable from site to site. The rainfall frequency analysis as a design tool has developed over the years in New Zealand from Seelye's daily rainfall frequency maps in 1947 to Thompson's web based tool in 2010. This paper will present a history of the development of New Zealand rainfall frequency analysis methods, and the details of the latest method, so that comparisons may in future be made with the development of Korean methods. One of the main findings in the development of methods was new knowledge on the distribution of New Zealand rainfall extremes. The High Intensity Rainfall Design System (HIRDS.V3) method (Thompson, 2011) is based upon a regional rainfall frequency analysis with the following assumptions: $\bullet$ An "index flood" rainfall regional frequency method, using the median annual maximum rainfall as the indexing variable. $\bullet$ A regional dimensionless growth curve based on the Generalised Extreme Value (GEV), and using goodness of fit test for the GEV, Gumbel (EV1), and Generalised Logistic (GLO) distributions. $\bullet$ Mapping of median annual maximum rainfall and parameters of the regional growth curves, using thin-plate smoothing splines, a $2km\times2km$ grid, L moments statistics, 10 durations from 10 minutes to 72 hours, and a maximum Average Recurrence Interval of 100 years.

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A lightweight technique for hot data identification considering the continuity of a Nand flash memory system (낸드 플래시 메모리 시스템 기반의 지속성을 고려한 핫 데이터 식별 경량 기법)

  • Lee, Seungwoo
    • Journal of Internet of Things and Convergence
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    • v.8 no.5
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    • pp.77-83
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    • 2022
  • Nand flash memory requires an Erase-Before-Write operation structurally. In order to solve this problem, it can be solved by classifying a page (hot data page) where data update operation occurs frequently and storing it in a separate block. The MHF (Multi Hash Function Framework) technique records the frequency of data update requests in the system memory, and when the recorded value exceeds a certain standard, the data update request is judged as hot data. However, the method of simply counting only the frequency of the data update request has a limit in judging it as accurate hot data. In addition, in the case of a technique that determines the persistence of a data update request, the fact of the update request is recorded sequentially based on a time interval and then judged as hot data. In the case of such a persistence-based method, its implementation and operation are complicated, and there is a problem of inaccurate judgment if frequency is not considered in the update request. This paper proposes a lightweight hot data determination technique that considers both frequency and persistence in data update requests.

Mapping out the surgical anatomy of the lingual nerve: a systematic review and meta-analysis

  • Sheena Xin Yi Lin;Paul Ruiqi Sim;Wei Ming Clement Lai;Jacinta Xiaotong Lu;Jacob Ren Jie Chew;Raymond Chung Wen Wong
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.4
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    • pp.171-183
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    • 2023
  • Objectives: Understanding the lingual nerve's precise location is crucial to prevent iatrogenic injury. This systematic review seeks to determine the lingual nerve's most probable topographical location in the posterior mandible. Materials and Methods: Two electronic databases were searched, identifying studies reporting the lingual nerve's position in the posterior mandible. Anatomical data in the vertical and horizontal dimensions at the retromolar and molar regions were collected for meta-analyses. Results: Of the 2,700 unique records identified, 18 studies were included in this review. In the vertical plane, 8.8% (95% confidence interval [CI], 1.0%-21.7%) and 6.3% (95% CI, 1.9%-12.5%) of the lingual nerves coursed above the alveolar crest at the retromolar and third molar regions. The mean vertical distance between the nerve and the alveolar crest ranged from 12.10 to 4.32 mm at the first to third molar regions. In the horizontal plane, 19.9% (95% CI, 0.0%-62.7%) and 35.2% (95% CI, 13.0%-61.1%) of the lingual nerves were in contact with the lingual plate at the retromolar and third molar regions. Conclusion: This systematic review mapped out the anatomical location of the lingual nerve in the posterior mandible, highlighting regions that warrant additional caution during surgeries to avoid iatrogenic lingual nerve injuries.