• Tuberculosis and Respiratory Diseases
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• v.84 no.1
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• pp.74-83
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• 2021

Background: This study compared the treatment outcomes of patients with multidrug-resistant tuberculosis (MDR-TB) before and after the implementation of public-private mix (PPM). Factors affecting treatment success were also investigated. Methods: Data from culture-confirmed pulmonary MDR-TB patients who commenced MDR-TB treatment at Pusan National University Hospital between January 2003 and December 2017 were retrospectively reviewed. Patients were divided into two groups in terms of PPM status: pre-PPM period, patients who commenced MDR-TB treatment between 2003 and 2010; and post-PPM period, patients treated between 2011 and 2017. Results: A total of 176 patients were included (64 and 112 in the pre- and post-PPM periods, respectively). 36.9% of the patients were resistant to a fluoroquinolone or a second-line injectable drug, or both. The overall treatment success rate was 72.7%. The success rate of post-PPM patients was higher than that of pre-PPM patients (79.5% vs. 60.9%, p=0.008). Also, loss to follow-up was lower in the post-PPM period (5.4% vs. 15.6%, p=0.023). In multivariate regression analysis, age ≥65 years, body mass index ≤18.5 kg/m², previous TB treatment, bilateral lung involvement, and extensively drug-resistant (XDR)- or pre-XDR-TB were associated with poorer treatment outcomes. However, the use of bedaquiline or delamanid for ≥1 month increased the treatment success. Conclusion: The treatment success rate in MDR-TB patients was higher in the post-PPM period than in the pre-PPM period, particularly because of the low rate of loss to follow-up. To ensure comprehensive patient-centered PPM in South Korea, investment and other support must be adequate.

• Journal of The Korean Society of Agricultural Engineers
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• v.52 no.2
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• pp.67-73
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• 2010

Unlike Urban building, horticultural facilities has a lot of heat loss through plastic or glass covering material which could be much influential to growing plant and consuming energy for heating greenhouse. In many cases, heat loss from a break of cover, a gap of joint sealing, the entrance to greenhouse and windows for ventilation are the main factors considered in calculating the heating load for horticultural facilities. however the normal observation through human eye and digital camera could not recognize where the heat loss occurred. but the infrared thermal image camera with detecting thermal difference could be very effective for noticing heat loss by analyzing infrared thermal image. In this study, greenhouse structure, covering material, internal and external provisions for Horticultural facilities were surveyed in different sites and Infrared thermal camera shooting and image analysis were performed for auditing heat loss from cultivation facilities The results from this study were that unexpected heat loss had been noticed in 7 representative cases of greenhouse such as side wall covered with single or double plastic, and the joint of horizontal thermal curtain, roof without horizontal thermal curtain, entrance to greenhouse, windows for ventilation. the most important factors for keeping heat energy were whether the horizontal thermal curtain with multifold thermal material was installed or not. The internal or external covering using multifold thermal curtain proved to be the most effective ways to keep heat energy from losing through heat transmission, heat radiation. from inside to outside the horticultural facilities.

• Korean Management Science Review
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• v.28 no.3
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• pp.73-82
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• 2011

Basel II advanced measurement approaches for operational risk need to estimate the frequency and severity distribution of operational losses. Due to lack of internal loss data, the estimation is impossible in many cases and so external loss data might be used by scaling on asset or gross income. To get around lack of loss data, scenario analysis combined with loss distribution approach can be useful in calculating the capital charge of operational risk. However, scenario based loss distribution approach requires much time and effort. Instead we may apply the analytic hierarchy process to measure operational risk of financial institutions. The analytic hierarchy process combined with loss distribution approach is to estimate the capital charge of operational risk in other areas based on the operational VaR in an area with sufficient loss data. AHP provides a tool for timely measurement of operational risk in this rapidly changing global environment.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2009.10a
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• pp.647-648
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• 2009

• Tuberculosis and Respiratory Diseases
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• v.63 no.4
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• pp.382-386
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• 2007

Paraneoplastic limbic encephalitis is a rare disorder that is characterized by personality changes, irritability, depression, seizures, memory loss and dementia, and is commonly associated with small cell lung cancer. The cause is unknown but it is believed to be an autoimmune disorder that develops secondary to a carcinomatous process. We report a patient with the clinical feature consistent with limbic encephalitis. A 64-year-old women developed disorientation, memory loss and general weakness. She was diagnosed with NSCLC (adenocarcinoma) with a brain metastasis 1 year earlier and was treated with radiation and chemotherapy. Although the lung mass and brain metastatic lesions had improved, the brain T2-weighted MRI showed high signal intensity in the right temporal region. This lesion consisted of with limbic encephalitis and was negative to the other viral and immune markers. The patient's symptoms did not improve after steroid treatment. Our case demonstrated that a NSCLC (adenocarcinoma) also can be associated with paraneoplastic limbic encephalitis.

• Journal of the Korean Society of Safety
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• v.31 no.5
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• pp.187-194
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• 2016

A single fire event within a fire area can cause multiple initiating events considered in internal events probabilistic safety assessment (PSA). For an example, a fire event in turbine building fire area can cause a loss of the main feed-water and loss of off-site power initiating events. This fire initiating event could result in special plant responses beyond the scope of the internal events PSA model. One approach to address a fire initiating event is to develop a specific fire event tree. However, the development of a specific fire event tree is difficult since the number of fire event trees may be several hundreds or more. Thus, internal fire events PSA model has been generally constructed by modifications of the pre-developed internal events PSA model. New accident sequence logics not covered in the internal events PSA model are separately developed to incorporate them into the fire PSA model. Recently, many fire PSA models have fire induced initiating event fault trees not shown in an internal event PSA model. Up to now, there has been no analytical comparative study on the constructions of fire events PSA model using internal events PSA model with and without fault trees of initiating events. In this study, the changing process of internal events PSA model to fire events PSA model is analytically presented and discussed.

• Journal of Internet Computing and Services
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• v.7 no.6
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• pp.113-121
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• 2006

To reduce switch cost, the optimum numbers of tunable wavelength converters (TWCs) and internal wavelengths required for contention resolution of asynchronous and variable length packets like internet traffics, is presented in the optical packet switch (OPS) with the shared fiber delay line (FDL) buffer. To optimize TWCs and internal wavelength related to on OPS design cost, we proposed a scheduling algorithm for the limited TWCs and internal wavelengths. For three TWC alternatives (not shared, partially shared, and fully shared cases), the optimum numbers of TWCs and internal wavelengths to guarantee minimum pocket loss are evaluated to prevent resource waste. Under o given load, TWCs and internal wavelengths could be significantly reduced, guaranteeing the same pocket loss probability as the performance of on OPS with full TWCs and internal wavelengths.

• Journal of Digestive Cancer Research
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• v.7 no.1
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• pp.18-21
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• 2019

Serine protease inhibitor Kazal-type 1 (SPINK1) is a gene expressed from pancreatic acinar cell which its mutation is known to be associated with chronic pancreatitis (CP) and pancreatic cancer. We report a case of a 47-years-old female with nausea and weight loss with yellow discoloration of skin. Initial imaging and endoscopic study led us to an impression of chronic pancreatitis with pancreatic cancer with common bile-duct dilation. Biopsy result was confirmed with pancreatic adenocarcinoma and additional imaging revealed lymph node and bone metastasis. Our genetic analysis revealed 194+2T>C mutation of SPINK1. Biliary obstruction was successfully decompressed by stent insertion and underwent chemotherapy and radiotherapy. Although there is accumulating evidence of association between SPINK1 mutation and CP, the relationship between SPINK1 mutation and pancreatic cancer in CP patient is an emerging concept. Genetic analysis should be considered in patients with young age especially when diagnosed with both CP and pancreatic cancer.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.10a
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• pp.568-571
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• 1997

The overall aim of this paper is to determine coupling loss factor using loss factor and structural loss factor. For this purpose, two kinds of loss factor were adopted. One is loss factor of each sub structure, another is structural loss factor based on the complex welded or assembled structure. Using these two parameters, it is possible to derive the coupling loss factor which represent characteristic condition of SEA theory. Coupling loss factor of conjunction in complex structure was expressed as power balance equation. The derived equation for a coupling loss factor has been simplified on the assumption of one directional power flow between two sub structures. Using these conditions, it is possible to find the coupling loss factor equation. The comparison between theory of power transmission on conjunction and above equation, show a good agreement in simple beam structure. To check the effectiveness of above equation, it was adopted rotary compressor. Rotary compressor has three main conjunctions between shell and internal vibration part. This equation was applied to find out the optimum welding point with respect to reduce the noise propagation. It shows the effective tool to evaluate the coupling loss factor in complex structure.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2009.10a
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• pp.210-210
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• 2009