• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.11
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• pp.1544-1553
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• 2018

Recently internal information leakage in industries is severely increasing in spite of industry security policy. Thus, it is essential to prepare an information leakage prevention measure by industries. Most of the leaks result from the insiders, not from external attacks. In this paper, a real-time internal information leakage prevention system via both storage and network is implemented in order to protect confidential file leakage. In addition, a Hadoop-based user behavior analysis and statistics system is designed and implemented for storing and analyzing information log data in industries. The proposed system stores a large volume of data in HDFS and improves data processing capability using RHive, consequently helps the administrator recognize and prepare the confidential file leak trials. The implemented audit system would be contributed to reducing the damage caused by leakage of confidential files inside of the industries via both portable data media and networks.

• Tuberculosis and Respiratory Diseases
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• v.46 no.1
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• pp.36-43
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• 1999

Background : Tumor growth is the net result of intrinsic proliferation and escape from active cell death. bcl-2 is a member of a new category of oncogenes that is not involved in influencing cell proliferation but is involved in regulating cell death(apoptosis). Based on this information, it seems to be reasonable to expect that there may be clinical prognostic significance of bcl-2 expression in non-small cell lung cancer. But its prognostic significance is not established. Methods: To investigate the role of bcl-2 in lung cancer, we performed immunohistochemical stain of bcl-2 on 57 biopsy specimens from resected primary non-small cell lung cancer. Thereafter, flow cytometric cell cycle analysis was done. And we analyzed the correlation between bcl-2 expression, clinical parameters, S-, $G_1$-phase fraction and survival. Results: bcl-2 were detected in 43.8% of total 57 patients(according to histology, squamous cancer 47%, adenocarcinoma 32%, according to TNM stage, I 28.6%, II 52.3%, III 45.5%. both differences were insignificant). By using the flow cytometric analysis, mean S-phase fraction of bcl-2(+) and (-) group were 14.1($\pm7.8$)%, 24.7($\pm10.5$)% (p<0.005), mean $G_1$-phase fraction of bcl-2(+) and bcl-2(-) group were 75.5($\pm10.8$)%, 65.5($\pm11.4$)%(p<0.05). 2yr, 3yr and 5yr survival and median survival time of bcl-2(+) group were 65%, 54%, 41%, 53 months, and those of bcl-2(-) group were 71%, 52%, 46%, 37 months. (p>0.05, Kaplan-Meier, log rank) Conclusion: bcl-2 was detected in 43.8% of primary non-small cell lung cancer. The S-phase fraction of bcl-2(+) group was less than bcl-2(-) group, and G1-phase fraction of bcl-2(+) group was more than bcl-2(-) group. But, expression of bcl-2 could not be a prognostic factor.

• Journal of Information Technology Services
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• v.4 no.1
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• pp.129-139
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• 2005

This paper proposes a framework of Operational Risk-based Business Continuity System(ORBCS), and develops protection system for operational risk through operational risk assessment and loss distribution approach based on risk management guideline announced in the basel II. In order to find out financial operational risk, business processes of domestic bank are assorted by seven event factors and eight business activities so that we can construct the system. After we find out KRI(Key Risk Indicator) index, tasks and risks, we calculated risk possibility and expected cost by analyzing quantitative data, questionnaire and qualitative approach for AHP model from the past events. Furthermore, we can assume unexpected cost loss by using loss distribution approach presented in the basel II. Each bank can also assume expected loss distributions of operational risk by seven event factors and eight business activities. In this research, we choose loss distribution approach so that we can calculate operational risk. In order to explain number of case happened, we choose poisson distribution, log-normal distribution for loss cost, and estimate model for Monte-Carlo simulation. Through this process which is measured by operational risk. of ABC bank, we find out that loss distribution approach explains closer unexpected cost directly compared than internal measurement approach, and makes less unexpected cost loss.

• Korean Journal of Clinical Pharmacy
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• v.16 no.1
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• pp.52-56
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• 2006

Aceclofenac, a nonsteroidal antiinflammatory agent of a phenylacetic acid type, has been used for rheumatoid arthritis and osteoarthrits. Although the metabolic pathway of aceclofenc is relatively well-known in vitro, pharmacokinetic profiles of its three major or metabolites are still unclear in human. The present study was designed to investigate pharmacokinetic profiles of the metabolites of aceclofenac, and to evaluate the bioequivalence of the generic preparation of aceclofenac 100 mg tablet. Blood samples were serially collected for a period of 12 hours following a single oral administration of 100 mg aceclofenac in 20 healthy human volunteers. A simple protein precipitation with acetonitrile was employed to purify those substances from plasma. Aceclofenac, diclofenac, 4'-hydroxyaceclofenac and 4'-hydroxy-diclofenac in heparinized plasma were simultaneously measured with flufenamic acid, an internal standard, using HPLC coupled to a tandem mass spectrometer. Time courses of 4'-hydroxydiclofenac, diclofenac and aceclofenac plasma concentrations were clearly revealed, and the pharmacokinetic properties were analyzed. The 90% confidence intervals for the ratios of test/reference for log-transformed AUC and $C_{max}$ lie within 0.80-1.25.

• Proceedings of the KSME Conference
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• 2001.06a
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• pp.211-216
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• 2001

The components with the circular cross section have the symmetric combination parts for rotating balance and the crack emanates from the symmetric combination parts. The symmetric cracks from symmetric combination parts make a decrease in the component fatigue life more than single crack. In this study, to estimate the behavior of symmetric cracks, the fatigue test was performed using rotary bending tester on the specimen with a symmetric defects in circular cross section. The material used in this study is Ni-Cr-Mo steel alloy. Under the same stress, the result from the rotary bending fatigue test turned out that the symmetric cracks made a decrease in the fatigue life by 35% more than single crack and the relation between log a and cycle ratio $N/N_f$ obtained linearly.

• Transactions of The Korea Fluid Power Systems Society
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• v.4 no.3
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• pp.13-21
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• 2007

A forklift is a motive machine powered by LPG, diesel engine or electric motors. The internal combustion engine type forklift is equipped with automatic transmission to meet the required drive load as well as the easy operation of the vehicle. This paper deals with the shift control and endurance test controller which is developed for the functional test of the newly designed automatic transmission on a dynamometer test bench. Its major function is to control the proportional solenoid currents, which is directly related to clutch pressures, for the given reference current trajectory during shift and sequential operation of shift schedule designed for the durability test at each gear. It also has the ability to monitor all the necessary test data through RS232 communication and log them to disk files. The current controller of embedded system is designed from the identified dynamics of solenoid coil and the current reference can be easily modified with a user interface software on PC so as to match the shift data by experiments.

• Tunnel and Underground Space
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• v.5 no.2
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• pp.114-122
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• 1995

The principle and applications of GPR(Ground Penetrating Radear) are familiar to engineering geologists and geophsicists as very attractive technique for continuous high resolution images of the subsurface. However, the main limitation of GPR is obviously related to presence of clayey or silty conductive soils, resulting in complete attenuation of radar signals. This difficulty gives hesitation for the exploration of the deeper targets for example detecting bedrock, particularly in Korean situation that most regions have conductive overburden. In order to prove usefulness of geological survey with GPR in that situation, the technique was tried to investigate depth of bedrock under thick conductive overburden and the other geolocgical informations for the constructionof foundation in the Dongbu apartment site, Kimhae. The reflection patterns on the processed GPR sections are well correlated with the geotechnical units-bedrock, alluvium, landfill unit and their internal layer-boundaries of boring data before GPR survey, except upper contact of bedrock. The isopach maps of the geotechnical units for the 3-D interpretations are made from GPR sections. The maps provided useful geological information that bedrock was distributed as plain and valley with 22~27m depth under alluvium unit (this depth is 5~8 m deeper than drill log) and sedimentary layers subsided and bended along growth fault with NNE strike/15$^{\circ}$SE dip in alluvium unit.

• YAKHAK HOEJI
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• v.46 no.2
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• pp.124-128
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• 2002

The nitrone-based free radical trapping reagent, $\alpha$-phenyl-n-tert-butyl nitrone (PBN) has been proposed as therapeutic agent for stroke. We used this for model drug of development of new drug for neuroprotection. The purpose of this study was to evaluate the blood-brain barrier (BBB) permeability of PBN in Sprague-Dawly (SD) rats. The BBB transport of PBN was investigated in SD rats using internal carotid artery perfusion (ICAP) method at a rate of 4 mι/min for 15 second. We also obtained pharmacokinetic parameters of PBN using single intravenous injection technique. When we estimated BBB permeability of PBN with ICAP method, the brain volume of distribution of PBN was 60.0 $\pm$ 12.0 $\mu\textrm{g}$/ι. The brain uptake of PBN after IV injection at 120 min was 0.15 $\pm$ 0.01%ID/g. The PBN was transported to the brain through the BBB well in rats, because PBN is small molecule (MW 177) and lipid-soluble (log P 1.23) compound.

• Wind and Structures
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• v.10 no.3
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• pp.269-285
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• 2007

This paper assesses the damage to high-set rectangular-plan houses with low-pitch gable roofs (built in the 1960 and 70s in the northern parts of Australia) to wind speeds experienced in tropical cyclones. The study estimates the likely failure mode and percentage of failure for a representative proportion of houses with increasing wind speed. Structural reliability concepts are used to determine the levels of damage. The wind load and the component connection strengths are treated as random variables with log-normal distributions. These variables are derived from experiments, structural analysis, damage investigations and experience. This study also incorporates progressive failures and considers the inter-dependency between the structural components in the house, when estimating the types and percentages of the overall failures in the population of these houses. The progressively increasing percentage of houses being subjected to high internal pressures resulting from damage to the envelope is considered. Results from this study also compare favourably with levels of damage and related modes of failure for high-set houses observed in post-cyclone damage surveys.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.2040-2041
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• 2007

In this paper, the UHF PD(Partial Discharge) sensors for $SF_6$ insulated MV $SF_6$ switchgear have been proposed and related investigations have been performed in order to detect the PD which were produced inside the MV $SF_6$ switchgear. Firstly, the internal type UHF PD sensor based on spiral antenna theory has been developed. This type sensor is highly sensitive and has lowly effect on by on-site noise. Secondly, the external type UHF PD sensor was developed based on log periodic antenna concept. This type sensor is removable and detectable for operating switchgear. These sensors were designed and simulated using RF simulation tool. In order to verify the sensitivity of these sensors, we performed the on-site test using the mock-up switchgears including the artificial defects which were the protrusion on high voltage conductor, free moving metal particle and surface defect on insulator. These mock-up switchgear were installed on the test distribution line.