• 대한한방내과학회지
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• 제36권4호
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• pp.547-561
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• 2015

Objectives In this study, we divided Korean asthma patients into excess syndrome or deficiency syndrome groups according to clinical phenotype. Genetic analysis was conducted to investigate the association of exonic SNPs in the CD46 gene polymorphism with the clinical phenotype based on the differentiation syndrome of the bronchial asthma patients.Methods There were 95 healthy patients (control group) and 53 asthma patients. (The deficiency syndrome group included 24 and the excess syndrome group 29). We searched the exonic areas of the CD46 gene in the NCBI website SNPs with <0.01 minor allele frequency (MAF) and <0.01 heterozygosity. We finally selected two SNPs: rs138843816, Ser13Phe and rs7144, 3’-UTR. Hardy-Weinberg equilibrium was calculated using SNPStats.Results There were significant differences in the codominant 1 model and the dominant model between the healthy group and the asthma group. There were significant differences between deficiency syndrome group and the excess syndrome group in the genotype frequencies and in the codominant 1 model, the dominant model, and the log-additive model. The allele frequency of rs7144C showed a significant difference between the deficiency syndrome group and the excess syndrome group. Two-SNP haplotype analysis showed a significant difference in frequency in the deficiency syndrome group and in the excess syndrome group. There were significant differences between the healthy group and the excess syndrome group in the codominant 1 model, the dominant model, and the log-additive model. The frequency of the rs7144 C allele exhibited a significant difference in the demonstration. SNP haplotype analysis between the healthy group and the excess syndrome group showed a significant difference in the frequency of the CT haplotype and the CC haplotype.Conclusions The results indicate that two CD46 SNPs (rs138843816, Ser13Phe and rs7144, 3′–UTR) might be associated with the symptomatic excess syndrome in Korean asthma patients.

• 한국컴퓨터정보학회논문지
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• 제10권3호
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• pp.259-265
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• 2005

정보 통신의 확산으로 일반 사용자도 정보 제공 매체 등을 통해 데이터베이스의 정보를 주고 받는 일련의 행위가 일상화되도록 변화되었다. 이러한 환경 변화는 데이터베이스에 대한 사용이 증가되고 사용의 편리성에 상반된 보안의 취약성을 야기한다. 본 논문에서는 이러한 문제점을 해결하기 위하여 패킷 분석을 통해 내부인 불법 질의를 탐지하는 방법을 제안한다. SQL 구문에 관련된 패킷을 분석 자료로 구축하기 위해서 네트워크 상의 패킷을 읽어 들여 각 프로토콜별로 헤더를 분석하였다. 패킷 중에서 TCP 세그먼트의 데이터부분에 SQL구문이 있는 경우 SQL 구문을 사용자 권한 정보와 사용자 하드웨어 정보를 이용하여 분석하므로 사용된 SQL 구문이 사용자의 접근 통제 범위내의 질의가 입력되었는지를 탐지할 수 있는 방법을 제안하고자 한다.

• 한국균학회지
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• 제46권4호
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• pp.495-503
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• 2018

2016년 4월부터 6월까지 표고 원목재배 임가 4곳과 표고 톱밥재배 임가 1곳의 재배사 내 실내 공기에서 진균을 포집 및 분리 동정하였다. 총 6개의 국내 미기록 진균(Cenangium acuum, Periconia macrospinosa, Neopestalotiopsissurinamensis, Metarhiziummarquandii, Trichoderma petersenii, Trichoderma paratroviride)을 분리하였으며 이들 균류에 대하여 형태학적 특성 및 internal transcribed spacer rDNA region, large subunitregion, ${\beta}-tubulin$ 또는 translation elongation factor $1{\alpha}$유전자 염기서열에 기반하여 계통학적 분석 결과를 기술하였다.

• Tuberculosis and Respiratory Diseases
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• 제62권5호
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• pp.389-397
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• 2007

연구배경: B-type natriuretic peptide(BNP)는 심인성 및 다른 쇼크 상태를 포함하는 심혈관 질환에서 사망을 예측하는 좋은 인자 중의 하나로 알려져 있다. 그러나, 급성호흡곤란증후군환자에서 이런 관계가 잘 알려져 있지 않는 바, 저자들은 BNP가 급성호흡곤란증후군 환자에서 사망을 예측할 수 있는 지를 연구하였다. 방 법: 본 연구는 전향적 관찰로 시행되었다. 급성호흡곤란증후군으로 진단된 환자들에게 심초음파 검사를 시행한 후, 좌심실 구획률이 50% 미만이거나 확장성 심부전 양상을 보인 환자들을 제외하였다. 2003년 12월부터 2006년 2월까지 총 47명의 환자가 채택되었다. 등록된 환자들은 24시간 내로 BNP를 포함한 여러 검사실 수치를 얻었으며, APACHE(Acute Physiology and Chronic Health Evaluation) II 점수를 구하였다. 결 과: BNP와 APACHE II 점수 평균값은 생존자군과 사망자군에서 유의한 차의를 보였다(BNP: $219.5{\pm}57.7pg/mL$ vs $492.3{\pm}88.8pg/mL$; p=0.013, APACHE II 점수: $17.4{\pm}1.6$ vs $23.1{\pm}1.3$, p=0.009). BNP 는 혈중 크레아티닌 수치와 양의 상관관계를 보였으나(r=0.374, p=0.01), 좌심실 구획률과는 유의한 관계가 없었다. Receiver operating characteristic 곡선상, BNP 수치를 585 pg/mL로 잡았을 때 사망을 예측하는데 있어서 94%의 특이도를 보였으며, APACHE II 점수의 경우에는 15.5를 기준으로 하였을 때 87%의 민감도를 보였다. 이 두 요소를 결합하여 '아파치II 점수+$11{\times}logBNP$' 수치를 계산하여 기준점을 46.14로 했을 경우, 사망 예측에 있어서 민감도 63%, 특이도 82%의 결과를 얻을 수 있었다. 결 론: 좌심실 기능 부전을 보이지 않는 급성호흡곤란증후군 환자에서 BNP 수치는 생존자군과 사망자군에서 유의한 차이를 보였으며 사망을 예측할 수 있었다. 향후 급성호흡곤란증후군 환자에 있어서 BNP와 관련된 연구가 더 필요하다고 생각된다.

• Tuberculosis and Respiratory Diseases
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• 제84권3호
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• pp.182-187
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• 2021

Background: Fractional exhaled nitric oxide (FeNO) is a non-invasive marker for eosinophilic airway inflammation and a good predictor of response to corticosteroids. There is a need for a reliable and accurate measurement method, as FeNO measurements have been widely used in clinical practice. Our study aimed to compare two FeNO analyzers and derive a conversion equation for FeNO measurements in adults. Methods: We included 99 participants who had chief complaints of chronic cough and difficulty in breathing. The participants underwent concurrent FeNO measurement using NIOX VERO (Circassia AB) and NObreath (Bedfont). We compared the values of the two devices and analyzed their correlation and agreement. We then formulated an equation to convert FeNO values measured by NObreath into those obtained by NIOX VERO. Results: The mean age of the participants was 51.2±17.1 years, with a female predominance (58.6%). Approximately 60% of the participants had asthma. The FeNO level measured by NIOX VERO (median, 27; interquartile range [IQR], 15-45) was significantly lower than that measured by NObreath (median, 38; IQR, 22-58; p<0.001). There was a strong positive correlation between the two devices (r=0.779, p<0.001). Additionally, Bland-Altman plots and intraclass correlation coefficient demonstrated a good agreement. Using linear regression, we derived the following conversion equation: natural log (Ln) (NObreath)=0.728×Ln (NIOX VERO)+1.244. Conclusion: The FeNO values of NIOX VERO and NObreath were in good agreement and had positive correlations. Our proposed conversion equation could help assess the accuracy of the two analyzers.

• Journal of Astronomy and Space Sciences
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• 제13권1호
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• pp.63-71
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• 1996

A total of 546 UBV photoelectric observations of AG Per was carried out from January to December in 1993 at Chungbuk National University Observatory. With our observations, UBV light curves were constructed, three minimum times of JDHel. 2449284.213, JDHel. 2449360.060, and JDHel. 2449363.192 were determined. The phase displacement of secondary minimum time $\delta$=-0.046 were determined and orbital eccentricity e=0.071 was calculated. Forty-five times of minimum light (including ours) were collected from the literature and plotted on O-C diagram. We analyzed these data and apsidal motion period of U=76.17 (years) was obtained. Using e and U for AG Per, the internal structure constant, log k2, was found to be -2.13.

• 디지털산업정보학회논문지
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• 제5권1호
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• pp.71-81
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• 2009

To the cause of the development of IT technology and the Internet, information leakage of industry is also facing a serious situation. However, most of the existing techniques to prevent leakage of information disclosure after finding the cause of defense. Therefore, in this paper by adding information about the Hardware to offer a way to protect the information. User authentication information to access the data according to different security policies to reflect a little more to strengthen security. And the security agent for the data by using a log of all actions by the record was so easy to analyze. It also analyzes and apply the different scenarios possible. And the analysis of how to implement and how to block. The future without the use of security agents to be able to control access to data and H/W information will be updated for the study will be done.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2017년도 추계학술대회
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• pp.34-35
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• 2017

Under the STCW Convention, marine engineers are required to have a satisfactory level of maritime English proficiency so that they can successfully perform their duties on board or maintain and operate the various equipment and facilities installed in the ship. More specifically, the importance of the engineers' written communication skills has been highlighted since their documents (for instance, post-work records, legal, and/or internal reports) have a significant legal impact in the event of a marine casualty or maritime crime. To suggest the necessity of developing standard engineering logbook phrases (SELP), therefore, this paper will closely analyse three-month authentic marine engineers' work records written by Korean officers. From the analysis, the problems and errors in the logbook will be analysed, and considerations to be taken into account in the development of SELP will be illustrated. Finally, the future actions for this standardised written communication for the logbook entry will be sought.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2005년도 춘계 학술발표회 논문집
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• pp.1377-1383
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• 2005

Mechanical properties of Municipal Solid Wastes(MSW) and their influencing parameters were studied by using a series of triaxial compression tests and resonant column tests. The shear strength of MSW can be modeled by a bilinear failure criterion. As the unit weight increasing, cohesion and internal friction were increased linearly on semi-log scale. As the proportion of waste to soil increases, maximum shear moduli tend to decrease whereas minimum damping ratios increase. Shear moduli and damping of degradable waste are higher than those of non-degradable MSW.

• 제어로봇시스템학회논문지
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• 제3권1호
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• pp.89-93
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• 1997

This paper describes the automatic testing system developed for powder metallurgy process using the visual inspection, and its some internal algorithms. The system consists of one unit from each of the five types of units; feeding, slot, vision inspection, volumn counter, and inferior good extractor units. Some applications of the system to powder metallurgy process has shown the possibility of reducing the rework and increasing the efficiency of operation.