• Journal of Ginseng Research
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• v.21 no.3
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• pp.174-186
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• 1997

In this study, rat hepatocytes known to have active carbohydrate metabolism were obtained by using the liver perfusion technique to examine the hypoglycemic action of red ginseng saponin components [ginsenoside (mixture, $Rb_1$, and $Rg_1$)] and incubated in two different media-one containing insulin and glucagon (control group), and the other containing glucagon only, The specific activities of some regulatory enzymes such as glucokinase, glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glucose 6-phosphatase, in main pathways which were directly related to the glucose metabolism were compared between these two kinds of hepatocytes cultured in two different media. The effects of red ginseng saponin components [ginsenoside (mixture, $Rb_1$, and $Rg_1$)] under the concentration of $10^3$~$10^6$% on these enzymes In hepatocytes were also investigated, when they were added to these two media. The results were as follows. The specific activity of enzymes such as glucokinase, glucose 6-phosphate dehydrogenase, and 6-phosphogluconate dehydrogenase related to glucose-consuming pathways of insulin-deficient group was much less than control one, however, their decreased activity was recovered after the addition of ginseng components at all range of concentrations. The increased specific activity of these on - zymes was shown by the addition of ginseng components to the control group. On the other hand, the specific activity of glucose 6-phosphatase related to glucose-producing pathway of insulin-deficient group was much higher than control one, but their Increased activity was decreased after the addition of ginseng components at all range of concentrations. The same results were obtained after the addition of ginseng components to the control group. These results suggest that the red ginseng saponin components might better diabetic hyperglycemia by regulating the activity of enzymes related to glucose metabolism directly and/or Indirectly though more detailed studies were needed.

• Korean Journal of Poultry Science
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• v.40 no.1
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• pp.49-55
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• 2013

The objective of this study was to compare the principle components and internal quality of eggs by age of laying hens and weight standard. The eggs (2,140 in total) used were from Hy-Line Brown reared from 18 to 63 weeks of ages and all were higher than appearance grade B by animal grading standard of Korea. Eggs were investigated their principle components, internal quality index, and their relationship. The weights of whole egg, shell, yolk, and albumen were increased while albumen height and Haugh unit were decreased by age of laying hens. When the composition of egg was investigated after sorting by ages, the ratio of egg yolk increased while that of albumen decreased. Egg shell composition was not shown significant difference by age. Age of laying hens had positive correlation with the weights of whole egg, shell, yolk, and albumen while albumen height and Haugh unit showed negative correlation. Also, the albumen height and Haugh unit were decreased by increase of weight of whole egg or principle components of egg.

• The Journal of Internal Korean Medicine
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• v.30 no.2
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• pp.375-387
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• 2009

Objective : Gyehyuldeung (GHD) has been widely used in oriental medicine for the treatments of cardiovascular and neurological disorders. Thus, its potential facilitatory activity on axonal regeneration was investigated in the rats. Methods: Sprague-Dawley rats were given crush injury at the sciatic nerve and the changes of axon growth after nerve injury on each nerve injury model were investigated with anti-NF-200 antibody, DiI, GAP-43 protein and Cdc2 protein Results : GHD-mediated enhancement of axonal regeneration after crush injury was measured in both qualitative and quantitative ways by immunofluorescence staining with anti-NF-200 antibody and retrograde tracing of fluorescence dye DiI. GAP-43 protein levels were elevated by GHD treatments in the distal injured sciatic nerve and DRG sensory neurons. The neurite outgrowth of DRG sensory neurons was facilitated by GHD treatment when co-cultured with Schwann cells and astrocytes prepared from injured sciatic nerves and injured spinal cord tissues, respectively. It was observed that Cdc2 protein was up-regulated in co-cultured Schwann cells or astrocytes and Cdc2 protein signals were co-localized to a certain extent with those of phospho-vimentin protein. Conclusions : These results suggest that GHD may play a facilitatory role in axonal regeneration by acting on the injured axons and adjacent non-neuronal cells. The current findings may be useful for the development of therapeutic targets through more specific explorations on molecular interactions between herbal components and endogenous factors.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.4
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• pp.903-907
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• 2009

The purpose of this study is to investigate the pattern of metabolic syndrome(Mets) in stroke patients who were hospitalized in Daejeon oriental hospital. The present study was done over 445 hospitalized patient with stroke in the Daejeon University Oriental Medical Hospital in the period of November 2006 to December 2008. Stroke patients had been interviewed by residents and specialists who studied standard operation procedures in Fundamental study for Standardization and Objectification of Differentiation and Pattern Identification of Syndrome of Oriental Medicine for Stroke. We analyzed all registered data and evaluated the prevalence of Mets and specific components of Mets. The distribution of Mets in stroke patients according to American Heart Association/National Heart Lung and Blood Institute(AHA/NHLBI) criteria is 65.63%. The distribution of Mets in stroke patients according to International Diabetes Federation(IDF) criteria is 48.05%. The distribution of female patients is higher than that of male patients. The distribution of central obesity, low HDL cholesterol and hypertension is higher in female patients. There is no significant relationship between Mets and stroke type in AHA/NHLBI criteria.. But, there is significant relationship between Mets and stroke type in IDF criteria.

• Journal of The Korean Society of Clinical Toxicology
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• v.3 no.1
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• pp.40-44
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• 2005

Nitrogen dioxide ($NO_2$), which produced during the process of silage, metal etching, explosives, rocket fuels, welding, and by-product of burning of fossil fuels, is one of major components of air pollutant. Accidental exposure of high level of $NO_2$ produces cough, dyspnea, pulmonary edema which may be delayed $4\~12$ hours and, in $2\~6$weeks, bronchiolitis obliterans. We experienced a case of acute pulmonary injuny induced by industrial exposure to high level of $NO_2$ during repair of $NO_2$ pipeline in a refinery. A 55-year-old man experienced nausea and severe dyspnea in 6 hours after $NO_2$ inhalation. Initial blood gas examination revealed severe hypoxemia accompanying increased alveolar-arterial O2 difference. Radiological examination showed diffuse ground glass opacities in both lung fields. Clinical symptoms and laboratory findings, including radiological study and pulmonary function test were improved with conservative treatment using inhaled oxygen and bronchodilator. and there was no evidence of bronchial fibrosis and bronchiolitis obliterance in chest high resolution computed tomography performed 6 weeks after exposure. Here, we report a case of $NO_2$ induced acute pulmonary injuny with a brief review of the relevant literature.

• Education of Primary School Mathematics
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• v.17 no.2
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• pp.77-93
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• 2014

The purpose of this study was to investigate the relationships between thinking styles and the components of mathematical ability of elementary math gifted children. The results of this study were as follows: First, there were differences in thinking styles: The gifted students prefer legislative, judical, hierarchic, global, internal and liberal thinking styles. General students prefer oligarchic and conservative thinking styles. Second, there were differences in components of mathematical ability: The gifted students scored high in all sections. And if when they scored high in one section, then they most likely scored high in the other sections as well. But the spacial related lowly to the generalization and memorization. There is no significant relationship between memorization and calculation Third, there was a correlation between thinking styles and components of mathematical ability: Some thinking styles were related to components of mathematical ability. In functions of thinking styles, legislative style have higher effect on calculation. And executive, judical styles related negatively to the inference ability. In forms of thinking styles monarchic style had higher effect on space ability, hierarchic style had higher effect on calculation. Monarchic, hierarchic styles related negatively to inference ability. In level of thinking styles global, local styles have higher effect on calculation. Local styles related negatively to the inference ability. In the scope of thinking styles, internal style had a higher effect on generalization, and external style had a higher effect on calculation. And there is no significant relationship leaning of thinking styles.

• Journal of Power Electronics
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• v.8 no.3
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• pp.228-238
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• 2008

Many induction motor broken bar diagnosis methods are based on evaluating special components in machine signals spectrums. Current, power, flux, etc are among these signals. Frequencies related to a broken rotor fault are slip dependent, therefore, correct diagnosis of fault - especially when obtrusive frequency components are present - depends on accurate determination of motor velocity and slip. The traditional methods typically require several sensors that should be pre-installed in some cases. This paper presents a diagnosis method based on only a vibration sensor. Motor velocity oscillation due to a broken rotor causes frequency components at twice slip frequency difference around speed frequency in vibration spectrum. Speed frequency and its harmonics as well as twice supply frequency, can easily and accurately be found in a vibration spectrum, therefore th motor slip can be computed. Now components related to rotor fault can be found. It is shown that a trained neural network - as a substitute for an expert person - can easily categorize the existence and the severity of a fault according to the features extracted from the presented method. This method requires no information about th motor internal and has been able to diagnose correctly in all the laboratory tests.

• The Journal of Korean Association of Computer Education
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• v.11 no.3
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• pp.21-32
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• 2008

The purpose of this study was to explore components of affective domains for teaching activities regarding computer education in elementary school. In addition, we investigated various influences on the components from teachers' responses. This paper included qualitative data collected from a total of thirteen teachers. Using qualitative analysis methods, we identified teachers' positive and negative emotions, attitudes, self-efficacy, expectations, interests, and internal and external motivations as well as various influences on the affective components. Therefore, we emphasize the importance of teachers' cognitive domains as well as affective domains to achieve the goals of the teaching of computer education. This study will contribute to research pertaining to the affective domains supporting successful teaching of computer education.

• Structural Engineering and Mechanics
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• v.53 no.1
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• pp.89-104
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• 2015

In current bridge management systems (BMSs), load and speed restrictions are applied on unhealthy bridges to keep the structure safe and serviceable for as long as possible. But the question is, whether applying these restrictions will always decrease the internal forces in critical components of the bridge and enhance the safety of the unhealthy bridges. To find the answer, this paper for the first time in literature, looks into the design aspects through studying the changes in demand by capacity ratios of the critical components of a bridge under the train loads. For this purpose, a structural model of a simply supported bridge, whose dynamic behaviour is similar to a group of real railway bridges, is developed. Demand by capacity ratios of the critical components of the bridge are calculated, to identify their sensitivity to increase of speed and magnitude of live load. The outcomes of this study are very significant as they show that, on the contrary to what is expected, by applying restriction on speed, the demand by capacity ratio of components may increase and make the bridge unsafe for carrying live load. Suggestions are made to solve the problem.

• Journal of Electrical Engineering and Technology
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• v.13 no.3
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• pp.1346-1354
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• 2018

Quality of the power system depends upon the reliability of its components such as transformer, transmission lines, insulators, circuit breakers and isolators. The transient voltage due to internal or external reasons may affect the insulation level of the components. The insulation level of these components must be tested against these conditions. Different studies, testing of different electrical components against high voltage impulses and different industrial applications rely on the international manufactures for pulsed power generation and testing, that is quite expensive and large in size. In this paper a model of impulse voltage generator with capacitive load of pin type insulator is studied by simulation method and by an experimental setup. A ten stage high voltage impulse generator (HVIG) is designed and implemented for different applications. In this proposed model, the cost has been reduced by using small and cheap capacitors as an alternative for large and expensive ones while achieving the same effectiveness. Effect of the distributed capacitance in each stage is analyzed to prove the effectiveness of the model. Different values of front and tail resistances have been used to get IEC standard waveforms. Results reveal the effectiveness at reduced cost of the proposed model.