• 제목/요약/키워드: Internal adaptation

검색결과 182건 처리시간 0.03초

Stress Adaptation of Escherichia coli as Monitored via Metabolites by Using Two-Dimensional NMR Spectroscopy

  • Chae, Young Kee;Kim, Seol Hyun
    • 한국자기공명학회논문지
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    • 제21권3호
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    • pp.102-108
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    • 2017
  • Escherichia coli responds to ever-changing external and internal stresses by rapidly adjusting its physiology for better survival. This adjustment occurs at all levels including metabolites as well as mRNAs and proteins. Although there has been many reports describing E. coli's adaptation to various stresses regarding transcriptomics or proteomics, only a few investigations have been reported regarding this adaptation viewed from metabolites' perspective. We applied four different types of stresses at four different doses as imposed by NaCl, sorbitol, ethanol, and pH to investigate the similarities or differences among the stresses, and which stress causes the largest perturbation of the metabolite composition. We profiled the metabolites under such external stresses by using two-dimensional NMR spectroscopy and identified 39 metabolites including amino acids, sugars, organic acids, and nucleic acids. According to our statistical analysis, the osmotic stress caused by sorbitol differentiated itself from others, while NaCl showed the largest dose dependent metabolic perturbations. We hope this work will form a foundation on which an approach to a successful protein production is systematically provided by a favorable metabolic environment by imposing proper external stresses.

한국판 사회적 외모불안 척도(Korean Version of the Social Appearance Anxiety Scale, K-SAAS) 타당화 (Validation of Korean Version of the Social Appearance Anxiety Scale)

  • 이민지;김미리혜;김정호
    • 대한불안의학회지
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    • 제19권1호
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    • pp.1-9
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    • 2023
  • Objective : To translate and adapt the Social Appearance Anxiety Scale into Korean and validate the Korean version of the social appearance anxiety scale, which measures the fear and anxiety about being negatively evaluated by others based on one's overall appearance, including body shape. Methods : For item translation and adaptation, six bilingual translators participated in the process of forward-adaptation and back-adaptation. Data were collected from undergraduate students. The sample size is 105 for Study 1 and 212 for Study 2. Classical item discrimination and difficulty analyses, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and reliability analysis were performed. Results : A unidimensional structure was found with a high internal consistency (Cronbach's α=0.95) and a high test-retest reliability (r=0.918). In addition, the concurrent validity was examined by correlations of the scale and several other scales measuring constructs related to social appearance anxiety. Conclusion : K-SAAS appears to be a reliable and valid scale for screening and assessing social appearance anxiety.

간호학과 남학생들의 학과 적응 경험 (Adaptation Experiences of Male Students in the Department of Nursing)

  • 김성혁;김순영
    • 한국산학기술학회논문지
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    • 제17권8호
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    • pp.113-126
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    • 2016
  • 본 연구는 간호학과에 재학 중인 남학생들을 대상으로 학과 적응 경험의 구성요소와 도움을 주는 요인을 밝혀냄으로써 지도적 중재에 필요한 자료를 제공하고자 하였다. 본 연구의 참여자는 간호학과에 재학 중인 남학생 7명이다. 심층면담을 통하여 수집된 자료는 Giorgi의 현상학적 분석 절차에 따라 분석하였다. 참여자의 학과 적응 경험의 핵심 구성요소는 '미래 진로에 대한 희망과 기대', '현실적 문제에 따른 갈등과 방황', '타협과 마음 다스림', '자기 성장을 위한 노력'으로 축약되었다. 이 구성요소들 간에는 인과적, 촉진적, 순환적 특성을 보여주었고, 학과 적응과정은 시간적 맥락에 따라 구조화 하고 있다. 이들이 원만한 학과 적응을 위해서는 자신의 의지력 강화, 확고한 진로의식 고취, 적응 전략의 채택 등 자신의 내적 통제가 중요하였으며, 가족과 친지, 선배 및 학과 교수의 지지가 학과 적응에 도움이 되는 요인으로 드러났다. 연구 결과를 토대로 제언하면, 간호학과 남학생들의 학과 생활 부적응으로 인한 탈락률을 파악하고 그 요인을 분석하는 후속연구가 필요하다. 또한 이들이 학과 생활 적응에 필요한 다양한 대처방식과 실천적 지지체계의 구축 및 지도 프로그램을 개발하여 적용하는 것이 필요하다.

현대 패션에 나타난 신체장식 표현의 미적 가치에 관한 연구 (A Study on the Aesthetic Value Featured in the Body Decoration in Contemporary Fashion)

  • 이정혜;김순자
    • 복식문화연구
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    • 제12권5호
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    • pp.721-736
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    • 2004
  • The aim of this study is to clarify aesthetic values and sociocultural meanings that reappears in contemporary fashion. In order to analyze aesthetic values and symbolic meanings of body decoration, I examined the concepts and expression methods of the body decoration. Also, analyzed external characteristics of expression and its internal meanings that applied in modern fashion. The expressions of body decoration represented in contemporary fashion are classified into direct and indirect methods. The direct method is expressed by tattoos, piercing, henna, make-up and body painting. And, indirect method is expressed by see-through look, body-conscious look and accessories that were utilized its patterns and the material adaptation methods. Such expression of body decoration in the modern fashion was represented into grotesque images and erotic images. The characteristics of grotesque images are abnormal state, hateful animal image and distorted or transformed body and the internal meanings are the pursuit of primitive, exoticism, the pursuit of playfulness, and resistance. The characteristics of erotic images are an exposure of body, see through, body-conscious and androgynous look and the internal meanings are the self-intoxication, naturalism and sexual pleasure.

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항암제로 유발된 백혈구감소증 회복에 미치는 황기의 효과 (The Effects of Astragali Radix on Cyclophosphamide-induced Leukocytopenia)

  • 한인선;김병우
    • 대한한방내과학회지
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    • 제27권3호
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    • pp.579-588
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    • 2006
  • Objective : This study was performed to investigate the effect of Astragali Radix on leukocytopenia anaphysis with carcinostatic substance elicitation. Methods : We observe if there were differences in a general tendency by EAR (AR extracts) capacity in the Astragali Radix treated group and the cyclophosphamide treated group, a general tendency of recovery from leukocytopenia over lime and checked for liver and kidney toxicity. Results : In cyclophosphamide treated with EAR 1000mg/kg group, the recovery rate of leukocytopenia increased and there were no differences in liver and kidney functions. Conclusions : Astragali Radix was effective and safe in increasing rate of leukocytopenia anaphysis with carcinostatic substance elicitation and indicated possibility for clinically adaptation.

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Cross-cultural adaptation and validation of the Turkish Yellow Flag Questionnaire in patients with chronic musculoskeletal pain

  • Koc, Meltem;Bazancir, Zilan;Apaydin, Hakan;Talu, Burcu;Bayar, Kilichan
    • The Korean Journal of Pain
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    • 제34권4호
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    • pp.501-508
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    • 2021
  • Background: Yellow flags are psychosocial factors shown to be indicative of long-term chronicity and disability. The purpose of the study was to evaluate the psychometric properties of the Turkish Yellow Flag Questionnaire (YFQ) in patients with chronic musculoskeletal pain (CMP). Methods: The cross-cultural adaptation was conducted with translation and back-translation of the original version. Reliability (internal consistency and test-retest) was examined for 231 patients with CMP. Construct validity was assessed by correlating the YFQ with the Hospital Anxiety and Depression Scale (HADS), Orebro Musculoskeletal Pain Questionnaire (OMPQ), and Tampa Kinesiophobia Scale (TKS). Factorial validity was examined with both exploratory and confirmatory factorial analysis. Results: The YFQ showed excellent test/retest reliability with an Intraclass correlation coefficient of 0.82. The internal consistency was moderate (Cronbach's alpha of 0.797). As a result of the exploratory factor analysis, there were 7 domains compatible with the original version. As a result of confirmatory factor analysis, the seven-factor structure of YFQ was confirmed. There was a statistically significant correlation between YFQ-total score and OMPQ (r = 0.57, P < 0.001), HADS-anxiety (r = 0.32, P < 0.001), HADS-depression (r = 0.44, P < 0.001), and TKS (r = 0.37, P < 0.001). Conclusions: This study's results provide considerable evidence that the Turkish version of the YFQ has appropriate psychometric properties, including test-retest reliability, internal consistency, construct validity and factorial validity. It can be used for evaluating psychosocial impact in patients with CMP.

공학계열 초기경력자의 학습과 적응을 위한 조직사회화 과정 연구 (A Study on the Organization Socialization Process of Engineering Novice for the Learning and Adaptation)

  • 이수용
    • 공학교육연구
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    • 제17권5호
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    • pp.41-50
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    • 2014
  • The purpose of this study was to examine the organization socialization process of engineering novice for the learning and adaptation. Qualitative case study was performed with 5 participants and the collected qualitative data were analyzed using funnel-like method. The findings showed that the organization socialization process proceed in three steps-anticipatory, encounter, and metarmorphosis. Engineering Novice look at the whole organization socialization proces of organization culture and job maladjustment, and the relationship between internal and external organizations to overcome the difficulties arising from the community through the process of becoming a full participant. Socialization of engineering novice is ultimately the organization to respond to new situations and changes in the learning process takes place in the process, talking about a major resource for human resources. This enables organizations to socialize and harmonious human relationships within the organization so that it can be more important than anything else.

무선네트워크에서의 종단간 QoS를 고려한 적응적 협상 인터페이스 (Adaptive Negotiation Interface for End-to-End QoS in Mobile Network)

  • 장익규;박홍성
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 심포지엄 논문집 정보 및 제어부문
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    • pp.68-70
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    • 2004
  • In this paper we develop an adaptive interface between video compression and transission protocols to handle QoS fluctuations that are common to mobile communication systems. We consider various generic design alternatives for QoS adaptation and identify 'QoS negotiation' as the most promissing. This method gives the best possibilities to obtain system-wide efficiency. To handle the indued system complexity we apply a design philosophy (called ARC) that separates implementation dependencies by introducing QoS interfaces between system modules. In the ARC phlosophy the implementation details are hidden in the subsystems. To assure efficient adaptation, the QoS must be negotiated between modules. We select the QoS parameters that are both necessary and sufficient for efficient negotiation between the video encoder and protocol modules. We describe the relation between the QoS parameters at the interface and the internal parameters of common video coding methods and protocol elements. Furthermore, we describe a negotiation procedure that allows a system-wide optimum to emerge.

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남성 간호사들의 임상간호현장 적응 경험 (Male Nurses' Adaptation Experiences in Clinical Nursing Settings)

  • 김성혁;김수진;강희경
    • 한국산학기술학회논문지
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    • 제18권8호
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    • pp.304-316
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    • 2017
  • 본 연구는 남성 간호사들의 임상간호현장 적응 경험의 구성요소와 적응에 도움을 주는 요인을 밝히는 것이다. 본 연구의 참여자는 종합병원에 재직하고 있는 남성 간호사 8명이다. 심층면담을 통하여 수집된 자료는 Giorgi의 현상학적 분석 절차에 따라 분석하였다. 참여자의 임상간호현장 적응 경험의 핵심 구성요소는 '주어진 업무에 전념하기', '기대와는 다른 현실에 도전하기', '직업적 정체성 확립하기', '미래를 위한 자기 개발하기'로 축약 되었다. 이 구성요소들 간의 관계는 인과적, 촉진적, 순환적 특성을 보여 주었고, 참여자들의 적응 경험은 시간적 맥락에 따라 구조화 하고 있다. 남성 간호사들이 원만한 임상간호현장 적응을 위해서는 이들의 근무 여건 조성을 위한 지지체계 확립, 성 차별 없는 공정한 인사 및 승진 기회 부여 등의 정책적 노력이 요구되며, 이들 스스로 의지력 강화와 적응 전략 채택을 통한 자기개발 노력의 내적 통제가 필요하다. 연구 결과를 토대로 제언하면, 본 연구의 결과를 바탕으로 이들의 임상간호현장에서 자리를 굳힐 수 있도록 돕는 전략 개발과 정책적 노력이 필요하다.

SLM 방식으로 제작한 도재관 금속하부구조물의 변연 및 내면 적합도 평가 (Evaluation of marginal and internal fit of metal copings fabricated by selective laser melting)

  • 배성령;이하빈;노미준;김지환
    • 대한치과기공학회지
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    • 제45권1호
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    • pp.1-7
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    • 2023
  • Purpose: To evaluate the marginal and internal fit of metal coping fabricated by a metal three-dimensional (3D) printer that uses selective laser melting (SLM). Methods: An extraoral scanner was used to scan a die of the prepared maxillary right first molar, and the coping was designed using computer-aided design software and saved as an stereo lithography (STL) file. Ten specimens were printed with an SLM-type metal 3D printer (SLM group), and 10 more specimens were fabricated by casting the castable patterns output generated by a digital light processing-type resin 3D printer (casting the 3D printed resin patterns [CRP] group). The fit was measured using the silicon replica technique, and 8 points (A to H) were set per specimen to measure the marginal (points A, H) and internal (points B~G) gaps. The differences among the groups were compared using the Mann-Whitney U-test (α=0.05). Results: The mean of marginal fit in the SLM group was 69.67±18.04 ㎛, while in the CRP group was 117.10±41.95 ㎛. The internal fit of the SLM group was 95.18±41.20 ㎛, and that of the CRP group was 86.35±32 ㎛. As a result of statistical analysis, there was a significant difference in marginal fit between the SLM and CRP groups (p<0.05); however, there was no significant difference in internal fit between the SLM group and the CRP group (p>0.05). Conclusion: The marginal and internal fit of SLM is within the clinically acceptable range, and it seems to be applicable in terms of fit.