Lee, Jin-Ah;Yoon, Ho Min;Choi, Youn Seon;Yeon, Jong Eun;Lee, June Young
Journal of Hospice and Palliative Care
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v.17
no.2
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pp.57-65
/
2014
Purpose: Since most terminally ill cancer patients die of multiple organ failure, plasma endotoxin concentration levels may be used to predict the life expectancy. This study was performed to evaluate the clinical significance of endotoxin level in plasma as a prognostic factor for survival in patients with terminal cancer. Methods: This study was conducted with 56 terminally ill cancer patients, above 20 years old, from April 2009 through October 2009. Demographic characteristics, Karnofsky performance status, and survival time were evaluated. We analyzed blood levels of white blood cell hemoglobin, hematocrit, aspartate aminotransferase, alanine aminotransferase, c-reactive protein, total bilirubin and endotoxin in each patient. Results: We considered following variable for univariate analysis: plasma endotoxin level, sex, age, WBC, hemoglobin, hematocrit, AST, ALT, total bilirubin, CRP and severity of pain. Univariate analysis did not show a significant association between plasma endotoxin level and survival time. However, in a multivariate analysis with factors that were found to be significantly associated with survival sex, WBC count and total bilirubin level in univariate analysis, high levels of plasma endotoxin and short survival time were significantly related. Conclusion: Plasma endotoxin level could be used as a prognostic factor to predict the life expectancy of terminally ill cancer patients.
From Nov. 1983 through Jan. 1986, 43 patients with nonsmall cell lung cancer were treated by radiation therapy at Inje Medical College Paik Hospital. 38 patients were available for the analysis of this study. 33 patients received definite irradiation with curative intent, while 5 patients received postoperative irradiation. Chemotherapy was added in 12 patients before, during and after radio-therapy. 28 patients were squamous cell carcinoma and 10 patients were adenocarcinoma. There were 29 men and 9 women (median age, 50 years; range 34 to 74 years). Stage 1 was 1 patient, Stage 11,7 patient, and Stage 111,30 patients. Among 33 patients who received radiotherapy with curative intent, follow up radiological study revealed complete response in 12 patients $(36\%)$, partial response, in 9 patients $(27\%)$, and minimal response, in 5 patients $(15\%)$, while 7 patients $(21\%)$ were nonresponders. Median survival for all patients was 6.9 months; squamous cell carcinoma, 7.3 months, adenocarcinoma, 5.9 months. Responders survived median 7 months, while nonresponders survived median 1.9 months. Improved complete response rate and survival were shown in high radiation dose group. As prognostic factors, age, initial performance status, sex, histology and tumor location were evaluated.
Kim, Chung-Hui;Kim, Gon-Sup;Park, Jung-Hee;Hah, Dae-Sik;Ryu, Jae-Doo;Son, Sung-Gi;Heo, Jung-Ho;Jung, Myung-Ho;Kim, Jong-Shu
Korean Journal of Veterinary Research
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v.42
no.2
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pp.171-181
/
2002
Simultaneous multiresidue analysis using liquid chromatography determination for five benzimidazole anthelmintics(thiabendazole, oxibendazole, albendazole, mebendazole and fenbendazole) in bovine muscle, liver and omasum has been described. Blank or benzimidazole-fortified samples(0.5g) were blended with bulk $C_{18}$($40{\mu}m$, 18% load, endcapped, 2g). A column made from the resultant $C_{18}$/animal tissue matrix was first washed with hexane($8m{\ell}$), following which the benzimidazoles were eluted with acetonitrile($8m{\ell}$). Analytes of extracted sample were determined by liquid chromatography with UV detector at 290nm. Correlation coefficients of standard curves for individual benzimidazole isolated from fortified samples, using internal standardization, were linear($0.991{\pm}0.007$ to $0.996{\pm}0.005$) with average relative percentage recoveries from $62.1{\pm}3.8(%)$ to $92.3{\pm}7.5(%)$ for the concentration range($0.2{\sim}6.4{\mu}g/g$), respectively. Recoveries rates of TBZ, MBZ in liver, OBZ, MBZ in muscle and TBZ, MBZ in omasium from fortified benzimidazole were 92.%, 87.3%, 74.5%, 82.7%, 75.2% and 83.5% at condition II, respectively. Condition II showed higher recoveries rates than condition I. These results indicated that the matrix solid phase dispersion(MSPD) methodology is acceptable for the determination of 5 benzimidazole anthelmintics and may also suitable for other matrixes of food animal origin.
Journal of the Institute of Electronics and Information Engineers
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v.53
no.10
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pp.123-130
/
2016
High-frequency induction heating equipment can heat the metal by applying a High-Frequency power to the resonant circuit. The resonance circuit is composed of the work coil and the conduction-cooled power capacitor, it influences the performance of the heat treatment equipment according to the characteristics of the capacitor. However, dependence on conduction-cooled power capacitor's import is high due to lack of core technology research and development. Minimizing the generation of internal heat transmitted inside during LC resonance, reduce the reactive power loss, there is a need for a capacitor within the voltage characteristic outstanding. To implement localization it is vital that prior study of the analysis on the frequency response characteristic for the finished capacitor advanced manufacturer be implemented. Studying the interpolation method to read the value at any point of the characteristic curve for a given log-log scale was applied to the analysis tool of the capacitor by my proposed algorithm. The simulation for reproducing frequency response curves was attempted by assuming a capacitor in a simplified series equivalent RC circuit to obtain the equivalent series resistance value. It was confirmed that the reproduction rate was the result value above 83% as compared to the simulation of the properties and characteristics on the actual reactive power for Peak value, and that the algorithm can be applicable when analyzing and predicting the characteristic curves of a simpled model capacitor.
Occupational ethical awareness is a system of norms and standards of behavior and an important component of professionalism that affects organizational performance and commitment. The purpose of this study is to examine the mediating effect of professionalism on the relationship between job ethics and organizational commitment of civil servants. A survey was conducted on 300 central government officials with more than one year of employment. 261 copies were used for the final analysis. The results are as follows. First, the vocational ethics of civil servants had a significant effect on professionalism. The higher the years of service, the higher the level of ethics. Second, the work ethic of public officials had a significant effect on organizational commitment. These results can be interpreted as the internal commitment of civil servants to the state of work ethic. Third, the mediating effect of professionalism was verified in the relationship between public morality and organizational commitment. Based on these results, the public ethics of public servants are the basis for accepting public values and goals. Vocational expertise with embedded codes of conduct and value systems influences organizational commitment. As a practical implication for improving the ethical ethics of public officials, education programs for improving ethical consciousness according to job titles and duties were provided, and the ethical ethical competence was presented.
Park Seung-Shik;Hong Sang-Bum;Lee Jai-Hoon;Cho Sung-Yong;Kim Seung-Jai
Journal of Korean Society for Atmospheric Environment
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v.22
no.2
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pp.259-266
/
2006
A dual-channel glass coil sampling technique was used to measure hourly formaldehyde concentration in the ambient air. The dual-channel coil sampling assembly consists of three parts; an all-pyrex 28-turn coil made of 0.2-cm internal diameter glass tubing for gas-liquid contact and scrubbing of soluble gases, an inlet section upstream of the coil for introducing sample air and scrubbing solution, and a widened glass section downstream of the coil for gas-liquid separation. The scrubbing solution used was a dilute aqueous DNPH (dinitrophenylhydrazine) solution. Hourly concentration of formaldehyde was determined at a Gwangju semi-urban site during two intensive studies between September and October using the dual channel glass-coil/DNPH sampling technique and HPLC (High Performance Liquid Chromatography) analysis. The mean concentration was 1.7($0.4{\sim}4.7$) and 3.0($0.5{\sim}19.1$) ppbv for the September and October intensives, respectively, which are considerably low, compared to those measured in polluted urban areas around the world including several urban areas of Korea. The diurnal variation showed significant increase of formaldehyde in the daytime suggesting the dominance of formation of formaldehyde due to photochemical oxidation of methane and other hydrocarbons. An increase in the formaldehyde sometimes in the night might be due to an increase in primary source, i.e. traffic emissions. It was also found that rapid increase in formaldehyde levels from 3.0 to 19.1 ppbv in the afternoon on October 20 was due to plumes from burning of agricultural wastes such as rice straw and stubble. It is expected from the measurement data that the constructed dual-channel glass coil sampling system can be utilized for measuring atmospheric concentration of the formaldehyde with high time resolution.
Journal of Advanced Marine Engineering and Technology
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v.40
no.7
/
pp.613-621
/
2016
This research connected network equipment, including CCTV, PAGA, IP-PBX, and Legacy, in order to enable the operation and configuration of internal IP-based network equipment in maritime plants and vessels, both in the field and from remote places, and to allow for the support of remotely controlling such equipment. It also realized an operating program for the integrated network equipment management system to enable the monitoring and control of equipment status, operation condition, and notifications from distant places. By applying the operating program to satellite stations and vessels sailing on the sea, a performance test was conducted to evaluate data loss and transmission/reception delay in the communication section between the land and vessels. As a result, this research verified the normal operation of CCTV control and of real-time monitoring and control of the network equipment, including PAGA, IP-PBX, and Legacy under the FBB and MVSAT environments. It was observed that the transmission of CCTV video images with a large volume of data as well as the transmission and reception of voice data were found to be slightly delayed, indicating the need to develop technology to compress and convert data for real-time transmission and reception.
Self-growing software is a software system that has the capability of evolving its functionalities and configurations by itself based on dynamically monitored situations. Self-growing software is especially necessary for intelligent service robots, which must have the capability to monitor their surrounding environments and provide appropriate behaviors for human users. However, it is hard to anticipate all situations that robots face with, and it is hard to make robots have all functionalities for various environments. In addition, robots have limited internal capacity. To support self-growing software for intelligent service robots, we are developing a cell-based distributed repository system that allows robots and developers transparently to share robot functionalities. To accomplish the creation of evolutionary repositories, we invented the concept of a cell, which is a logical group of distributed repositories based upon the functionalities of components. In addition, a cell can be used as a unit for the evolutionary growth of the components within the repositories. In this paper, we describe the requirements and architecture of the cell-based repository system for self-growing software. We also present a prototype implementation and experiment of the repository system. Through the cell-based repositories, we achieve improved performance of self-growing actions for robots and efficient sharing of components among robots and developers.
Journal of the Korea Academia-Industrial cooperation Society
/
v.18
no.12
/
pp.539-547
/
2017
This paper reports the results of descriptive research aimed at determining the effects of the administrative hospital staff members' organization-based self-esteem and work engagement on their organizational citizenship behaviors. The participants of the study were 200 administrative staff members of general hospitals, each with 200 beds or more, located in B city. Data were collected from March 15 to 30, 2017, and analyzed statistically using a t-test, ANOVA, Pearson's correlation coefficient, and multiple regression analysis. The findings of this study can be summarized as follows. The organizational citizenship behaviors differed significantly according to whether they had an experience of turnover (t=-4.260, p=.000) and how long they had served at their present work (t=3.297, p=.039). In addition, the organizational citizenship behaviors had strong positive correlations with the organization-based self-esteem (r=.454, p=<.000) and work engagement (r=.595, p<.000). In addition, the factor that explained the organizational citizenship behaviors most significantly was work engagement, followed by organization-based self-esteem and the period of service at the present work. All three factors accounted for 41% of those behaviors. These findings suggest that the hospital should perform internal marketing or improve its welfare system to make administrative staff members raise their self-esteem based on their organization. Moreover, the hospital should form an organizational culture of its own, in which administrative staff members feel the importance of their job, enjoy it and are given autonomy in job performance, ultimately contributing to the development of hospital management.
Park, Jee Min;Moon, Joo Hyun;Lee, Hyung Ju;Lee, Seong Hyuk
Journal of the Korea Academia-Industrial cooperation Society
/
v.19
no.9
/
pp.69-76
/
2018
The present study analyzed the effect of film hole position of 45 degree ribbed cooling channel on film cooling performance of gas turbine blades. We also investigated the influence of the ribs under the fixed blowing ratio. Three-dimensional numerical model was constructed and extensive simulation was conducted using the commercial code (Fluent ver. 17.0) under steady-state condition. Base on the simulation results, We investigated the cooling effectiveness, flow velocity, streamline, and pressure coefficient. Moreover, We analyzed the effect of cooling hole position on ejection of the secondary flow caused by the rib structure. From the results, It was found that internal flow of the cooling channel forms a vortex pair in the counterclockwise from the top side, and clockwise from the bottom side. For the channels with ribs, the vortex flow generated by the ribs caused a higher pressure difference near the hole outlet, resulting in at least 12% higher cooling effectiveness than the channel without ribs. Additionally, when the hole is located on the left side of the ribbed channel (Rib-Left), it can be found that the secondary flow generated by the ribs hits against wall surface near the hole to form a flow in the direction of the hole inclination angle. Therefore, It is considered that the region where the cooling gas discharged to the blade surface stays in the main flow boundary layer is wider than the other cases. In this case, The largest pressure coefficient difference was observed near the outlet of the hole, and as a result, the discharge of the cooling gas was accelerated and the cooling efficiency was slightly increased.
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