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Association of Hospital Procedure Volume with Post-Transplant Survival for Allogeneic Bone Marrow Transplantation (동종조혈모세포이식술 시술기관의 진료량이 이식후 생존율에 미치는 영향)

  • Park, Choon-Seon;Moon, Hee-Kyung;Kang, Hye-Young;Min, Yoo-Hong;Cho, Woo-Hyun
    • Journal of Preventive Medicine and Public Health
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    • v.37 no.1
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    • pp.26-36
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    • 2004
  • Objective : To examine the association between hospital procedure volume and treatment outcomes following allogeneic bone marrow transplantation (allo-BMT). Methods : Out of 1,050 patients who received allo-BMTs between 1998 and 2000 in 21 Korean hospitals, 752 with first allo-BMT and complete data were included in this study. Study subjects were divided into the following three groups according to cumulative hospital experience of all-BMTs during the study period: low (<30 cases), medium (30-49) and high ($\geq$50 cases) volume. Patient outcome was defined as early survival at day 100 and one-year survival. Multiple logistic regression analyses were performed to examine the association between hospital experience and survival at day 100 and one year. Results : When the low volume group was defined as the reference group, the adjusted relative risks (RR) of survival at day 100 for the high volume group were 2.46(95% CI, 1.13-5.36) for all patients, 2.61(1.04-6.57) for those with leukemia, and 2.20(0.47-10.32) for those with aplastic anemia. For one-year survival, adjusted RR for the high volume group were 2.52(1.40-4.51) for all patients, 1.99 (1.01-3.93) for leukemia, and 6.50(1.57-26.80) for aplastic anemia. None of the RR for the medium volume group was statistically significant. Patient factors showing significant relationship with survival were donor-recipient relation, human leukocyte antigen matching status, time from diagnosis to transplant, and disease stage. Conclusions : The study results suggest that the cumulative experience of hospitals in providing allo-BMT is positively associated with patient survival.

A Finite-difference Modeling of Love Channel Waves in Transversely Isotropic Medium (유한차분식을 이용한 Transverse 이방성(異方性) 매질내 Love채널파동 연구)

  • Cho, Dong-Heng;Lee, Sung-Soo
    • Economic and Environmental Geology
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    • v.27 no.3
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    • pp.281-287
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    • 1994
  • The present paper deals with numerical modeling of Love channel waves in transversely isotropic elastic medium. First, an explicit finite-difference scheme of second order approximation is formulated with the wave equation of SH particle displacement in transversely isotropic medium. Since it is a heterogeneous formulation, it should enable efficient modeling of complex model structures without additional treatment of the internal boundary matching. With a model of isotropic coal seam embedded in high velocity host rock, seismograms are synthesized and tutn out to be essentially identical with published ones of Korn and $St{\ddot{o}}ckl$. Next, anisotropic coal seams are investigated. It is found that the horizontal velocity of the seam appears to play a major role of determining the group velocity of Love channel waves. The group velocity increases with the increase of the horizontal velocity or vice versa. However, further study will be needed to exploit fully Love channel waves for the determination of lithology, stratification, fracture in sedimentary rocks, for instance, for hydrocarbon exploration and development.

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Development of Isotope Dilution LC-MS/MS Method for Accurate Determination of Arsenobetaine in Oyster Certified Reference Material

  • Lee, Woo Young;Yim, Yong-Hyeon;Hwang, Euijin;Lim, Youngran;Kim, Tae Kyu;Lee, Kyoung-Seok
    • Bulletin of the Korean Chemical Society
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    • v.35 no.3
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    • pp.821-827
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    • 2014
  • An isotope dilution liquid chromatography tandem mass spectrometry (ID LC-MS/MS) method has been developed and applied to the determination of arsenobetaine (AsB, ${(CH_3)_3}^+AsCH_2COO^-$) from oyster candidate certified reference material (CRM). The exact matching isotope dilution approach was adopted for accurate determination of AsB using $^{13}C_2$-labeled AsB as an internal standard. Efficiencies of different AsB extraction methods were evaluated using a codfish reference material and a simple sonication method was selected as the method of choice for the certification of the oyster candidate CRM. The hydrophilic interaction liquid chromatography (HILIC) combined with electrospray ionization tandem mass spectrometry (ESI/MS/MS) in selected reaction monitoring (SRM) mode was optimized for adequate chromatographic retention and robust quantification of AsB from codfish and oyster samples. By analyzing 12 subsamples taken from each 12 bottles systematically selected from the whole oyster CRM batch, the certified value of AsB was determined as $6.60mg{\cdot}kg^{-1}{\pm}0.31mg{\cdot}kg^{-1}$ and it showed excellent between-bottle homogeneity of less than 0.42%, which is represented by relative standard deviation of 12 bottles from the CRM batch. The major source of uncertainty was the certified value of the AsB standard solution.

Enhancing Red Tide Image Recognition using NMF and Image Revision (NMF와 이미지 보정을 이용한 적조 이미지 인식 향상)

  • Park, Sun;Lee, Seong-Ro
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.2
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    • pp.331-336
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    • 2012
  • Red tide is a temporary natural phenomenon involving harmful algal blooms (HABs) in company with a changing sea color from normal to red or reddish brown, and which has a bad influence on coast environments and sea ecosystems. The HABs have inflicted massive mortality on fin fish and shellfish, damaging the economies of fisheries for almost every year from 1990 in South Korea. There have been many studies on red tide due to increasing damage from red tide on fishing and aquaculture industry. However, internal study of automatic red tide image classification is not enough. Especially, extraction of matching center features for recognizing algae image object is difficult because over 200 species of algae in the world have a different size and features. Previously studies used a few type of red tide algae for image classification. In this paper, we proposed the red tide image recognition method using NMF and revison of rotation angle for enhancing of recognition of red tide algae image.

Localization of Unmanned Ground Vehicle using 3D Registration of DSM and Multiview Range Images: Application in Virtual Environment (DSM과 다시점 거리영상의 3차원 등록을 이용한 무인이동차량의 위치 추정: 가상환경에서의 적용)

  • Park, Soon-Yong;Choi, Sung-In;Jang, Jae-Seok;Jung, Soon-Ki;Kim, Jun;Chae, Jeong-Sook
    • Journal of Institute of Control, Robotics and Systems
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    • v.15 no.7
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    • pp.700-710
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    • 2009
  • A computer vision technique of estimating the location of an unmanned ground vehicle is proposed. Identifying the location of the unmaned vehicle is very important task for automatic navigation of the vehicle. Conventional positioning sensors may fail to work properly in some real situations due to internal and external interferences. Given a DSM(Digital Surface Map), location of the vehicle can be estimated by the registration of the DSM and multiview range images obtained at the vehicle. Registration of the DSM and range images yields the 3D transformation from the coordinates of the range sensor to the reference coordinates of the DSM. To estimate the vehicle position, we first register a range image to the DSM coarsely and then refine the result. For coarse registration, we employ a fast random sample matching method. After the initial position is estimated and refined, all subsequent range images are registered by applying a pair-wise registration technique between range images. To reduce the accumulation error of pair-wise registration, we periodically refine the registration between range images and the DSM. Virtual environment is established to perform several experiments using a virtual vehicle. Range images are created based on the DSM by modeling a real 3D sensor. The vehicle moves along three different path while acquiring range images. Experimental results show that registration error is about under 1.3m in average.

An Analysis and Design of Wideband Microstrip Rotman Lens by Contour Integral and Segmentation Method (경계적분법과 세그멘테이션 기법에 의한 광대역 마이크로스트립 로트만 렌즈의 해석 및 설계)

  • 이광일;오승엽
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.7
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    • pp.769-776
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    • 2003
  • This paper presents analysis and design of microstrip Rotman lens operating over wide band and wide steering angle by the contour integral method along with the segmentation method. All mutual coupling, internal reflections between ports and the discontinuity at every junction are taken into account. Equally spaced ports are designed and realized, which make suppress output ripple through the array ports. Impedance matching and mutual coupling between ports are analyzed and optimized using 12 input and 12 output exponential tapers. The measured results of fabricated lens show ${\pm}$ 1.8 dB insertion loss deviation over 6∼18 GHz wide frequency range and beam steering accuracy less than 1$^{\circ}$over ${\pm}$53$^{\circ}$angle and agrees well with the analysis results.

Long-Term Nutritional Outcomes of Near-Total Gastrectomy in Gastric Cancer Treatment: a Comparison with Total Gastrectomy Using Propensity Score Matching Analysis

  • Seo, Ho Seok;Jung, Yoon Ju;Kim, Ji Hyun;Park, Cho Hyun;Kim, In Ho;Lee, Han Hong
    • Journal of Gastric Cancer
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    • v.18 no.2
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    • pp.189-199
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    • 2018
  • Purpose: This study sought to examine whether near total gastrectomy (nTG) confers a longterm nutritional benefit when compared with total gastrectomy (TG) for the treatment of gastric cancer. Materials and Methods: Patients who underwent nTG or TG for gastric cancer were included (n=570). Using the 1:2 matched propensity score, 25 patients from the nTG group and 50 patients from the TG group were compared retrospectively for oncologic outcomes, including long-term survival and nutritional status. Results: The length of the proximal resection margin, number of retrieved lymph nodes and tumor nodes, metastasis stage, short-term postoperative outcomes, and long-term survival were not significantly different between the groups. The body mass index values, and serum total protein and hemoglobin levels of the patients decreased significantly until postoperative 6 months, and then recovered slightly over time (P<0.05); however, there was no difference in the levels between the groups. The prognostic nutritional index values and serum albumin levels decreased significantly until postoperative 6 months and then recovered (P<0.05); the levels decreased more in the nTG group than in the TG group (P<0.05). The mean corpuscular volumes and serum transferrin levels increased significantly until postoperative 1 year and then recovered slightly over time (P<0.05); however, there was no difference between the groups. Serum vitamin $B_{12}$, iron, and ferritin levels of the patients did not change significantly over time, and no difference existed between the groups. Conclusions: A small remnant stomach after nTG conferred no significant nutritional benefits over TG.

Performance and analysis of wireless power charging system from room temperature to HTS magnet via strong resonance coupling method

  • Chung, Y.D.;Lee, C.Y.;Lee, S.Y.;Lee, T.W.;Kim, J.S.
    • Progress in Superconductivity and Cryogenics
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    • v.18 no.1
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    • pp.41-45
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    • 2016
  • The technology of supplying the electric power by wireless power transfer (WPT) is expected for the next generation power feeding system since it can supply the power to portable devices without any connectors through large air gap. As such a technology based on strongly coupled electromagnetic resonators is possible to deliver the large power and recharge them seamlessly; it has been considered as a noble option to wireless power charging system in the various power applications. Recently, various HTS wires have now been manufactured for demonstrations of transmission cables, motors, MAGLEV, and other electrical power components. However, since the HTS magnets have a lower index n value intrinsically, they are required to be charged from external power system through leads or internal power system. The portable area is limited as well as the cryogen system is bulkier. Thus, we proposed a novel design of wireless power charging system for superconducting HTS magnet (WPC4SM) based on resonance coupling method. As the novel system makes possible a wireless power charging using copper resonance coupled coils, it enables to portable charging conveniently in the superconducting applications. This paper presented the conceptual design and operating characteristics of WPC4SM using different shapes' copper resonance coil. The proposed system consists of four components; RF generator of 370 kHz, copper resonance coupling coils, impedance matching (IM) subsystem and HTS magnet including rectifier system.

Analysis of On-line Personal Image Consulting Program Contents (온라인 퍼스널 이미지 컨설팅 프로그램의 컨텐츠 현황 분석)

  • Kim, Ri-Ra;Chung, Su-In;Kim, Yoo-Jung;Kim, Young-In
    • Journal of the Korean Society of Costume
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    • v.62 no.4
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    • pp.58-68
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    • 2012
  • Personal image concerns a person's talent, expertise, as well as the internal and external image. It is a core value that differentiates one individual from another. As personal branding via personal image management has become more important, there is a fast-growing number of online systems that provide self-test programs to analyze one's style and habits and also provide expert advice for not only styles but lifestyles as well. This study develops a systematic and objective personal image consulting system and offers basic information for the research of personal image making. For that purpose, the study attempts to examine the present state of global companies that use online image consulting programs and analyze their digital content. The results are as follows: 1) two domestic companies, Colorz and Atzine, and seven foreign companies, notably Covet and Boutique, were brisk in business; 2) two types of personal image-diagnosis programs - Visual search and Virtual matching - are now in operation; and 3) mobile applications exist as an evolved personal image-diagnosis program. With an increased interest in such programs, various companies at home and abroad are establishing systematic and scientific analysis systems, which are needed for personal image-making online. Under these circumstances, domestic companies are also urged to enhance levels of image-diagnosis content and actual commercialization and utilization, to develop programs that enable objectified, systematic personal image-making. To this end, the results of this study may serve as a helpful tool to consider future directions.

Microarray Data Retrieval Using Fuzzy Signature Sets (퍼지 시그너쳐 집합을 이용한 마이크로어레이 데이터 검색)

  • Lee, Sun-A;Lee, Keon-Myung;Ryu, Keun-Ho
    • Journal of the Korean Institute of Intelligent Systems
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    • v.19 no.4
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    • pp.545-549
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    • 2009
  • Microarray data sets could contain thousands of gene expression levels and have been considered as an important source from which meaningful patterns could be extracted for further analysis in biological studies. It is sometimes necessary to retrieve out specific genes or samples of analyst's interest in an effective way. This paper is concerned with a method to make use of fuzzy signature set in order to filter out genes or samples which satisfy complicated constraints as well as simple ones. Fuzzy signatures are an extension of vector valued fuzzy sets, in which elements of the vector are allowed to have a vector. Fuzzy signature sets are similar to fuzzy signatures except that their leaf elements are fuzzy sets defined on the interval [0,1]. This paper introduces an extension of fuzzy signature sets which specifies aggregation operators at each internal node and comparison operators for aggregation. It also shows how to use the extended fuzzy signature sets in microarray data retrieval and some examples of its usage.