• 한국전기전자재료학회논문지
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• 제14권7호
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• pp.578-583
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• 2001

The bushing for high voltage and large and power should endure weight of itself and force of pushing from contact with circuit breaker. Like this, epoxy mold bushing has to be strong without fault. However, the external circumstances and internal factors was caused by partial discharge, flashover and dielectric breakdown. Therefore, to remove external factor of defect and to prevent the internal cracks and cavity generated from the contraction on interface of Cu-Epoxy, we should form semi-conductive layer on Cu bar by carbon. Then, the PD properties and the insulation qualities of epoxy mold type bushing was able to improved by roles of cushions for the direction of diameter and by effects fo natural sliding like as separated from conductor for the direction of length. So, in this work, we could prove the method of semi-conductive layer in making the long conductor.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.333-338
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• 2001

The object of this work is to develop an assessment system for pipeline integrity. The system consists of four module applications for internal algorithm; the effect of corrosion in pipeline, crack, stress corrosion crack (SCC) and fatigue modules and the effect of cavity. Presently, the module of the external corrosion has been developed and the internal algorithm for the effect of corrosion in pipeline and the database of the system are described in this paper. The database of the system is separated to mainly four parts; geometry of pipeline, material properties, boundary conditions and general properties. Each components of the system are designed by user-friendly concept. This system may give a guideline for maintenance and modifications for the pipeline at the industrial sight. Furthermore, a procedure to evaluate an inspection interval is also provided.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2005년도 추계 학술대회논문집
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• pp.235-238
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• 2005

The unsteady supersonic flow over two- and three-Dimensional cavities has been analyzed by the integration of unsteady Reynolds-Averaged Navier-Stokes(RANS) with the k - w turbulence model. The unsteady flow is characterized by the periodicity due to the mutual relation between the shear layer and the internal flow in cavities. Numerical method is upwind TVD scheme based on the flux vector split with the Van Leer limiters, and time accuracy is used explicit 4th stage Runge-Kutta scheme. Cavity flows are Comparison of two- and three-dimensional. The cavity has a L/D ratio of 3 for two-dimensional case. and same L/D and W/D ratio is 1 for three-dimensional case. The Mach and Reynolds numbers are held constant at 1.5 and 450000 respectively. For the three-dimensional case, the flow field is observed to oscillate in the 'shear layer mode' with a feedback mechanism that follow Rossiter's formula. On the other hand, the self-sustained oscillating flow transitions to a 'wake mode' for the two-dimensional simulation, with more violent fluctuations inside the cavity.

• 한국전산유체공학회지
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• 제10권4호통권31호
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• pp.51-58
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• 2005

The unsteady supersonic flow over two- and three-dimensional cavities has been analyzed by the integration of unsteady Reynolds-Averaged Navier-Stokes(RANS) with the k-$\omega$ turbulence model. The unsteady flow is characterized by the periodicity due to the mutual relation between the shear layer and the internal flow in the cavity. An explicit 4th order Runge-Kutta scheme and an upwind TVD scheme based on the flux vector split with the van Leer limiters are used for time and space discritizations, respectively. The cavity has a L/D ratio of 3 for two-dimensional case, and same L/D and W/D ratio of I for three-dimensional case. The Mach and Reynolds numbers are 1.5 and 450000 respectively. In the three-dimensional flow, the field is observed to oscillate in the 'shear layer mode' with a feedback mechanism that follows Rossiter's formula. In the two-dimensional simulation, the self-sustained oscillating flow has more violent fluctuation inside the cavity. The primary fluctuating frequencies of two- and three- dimensional flow agree very well with the 2nd mode of Rossiter's frequency. In the three-dimensional flow, the 1st mode of frequency could be seen.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 추계학술대회논문집
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• pp.196-199
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• 2005

Flow traveling over a cavity opening forms a vortex due to unstable shear layer and induces an aerodynamic pressure excitation from the diffusion of the vortex convecting out of the trailing edge of the opening. The interaction between the excitation force and the cavity response sustains resonance in the resonator(cavity) and locked-in vortex shedding at the leading edge of the opening. The aerodynamic excitation force can be described from the diffusion of the vortex over the trailing edge and the level of its diffusivity is related to the strength of vorticity seeded at the loading edge. In this study, the control scheme of the internal pressure oscillation was proposed from regulating the vorticity at the leading edge by use of an oscillating spoiler. It was found that the relative motion between the spoiler and the air mass at the cavity opening influenced vorticity strength and the control was achieved by direct feedback of the cavity pressure fluctuation to the actuator.

• 대한한방내과학회지
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• 제30권2호
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• pp.399-409
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• 2009

Objectives : The aim of this study was to experiment the antitumor activity of Agrimonia pilosa Ledebour (APL) in human stomach cancer (AGS) cell lines (in vitro) and male C57BL/6J mouse (in vivo). Methods : The effects of the ethanol extract from the plant on several transplantable rodent tumors were investigated in vitro by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxy phenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt (MTS) assay. DNA content analysis and Western blot analysis. Agrimonia pilosa Ledebour (APL) was given to rats with Lewis Lung Carcinoma (LLC) cells. The experimental rats were divided into 3 groups in vivo. Saline was injected into the abdominal cavity in the first group, 50 mg/kg APL was injected into the abdominal cavity in the second group and 100 mg/kg was injected into the abdominal cavity in the third group. After that, we checked their tumor volume periodically. Results : At first, human gastric cancer (AGS) cell lines (in vitro) showed decreased cell viability, and increased $sub-G_1$ contents. When we experimented rat intestinal epithelial (RIE)l as same condition, this result didn't show. With this, compared to normal cells, Agrimonia pilosa Ledebour (APL) led selectively to the extinction of cells only in human gastric cancer. Moreover, we showed that the traditional herbal medicine APL induced caspase-dependent apoptosis in AGS cells. Next, APL inhibited the growth of LLC-bearing mouse tumor. However, we could not verify APL induced caspase-dependent apoptosis in LLC-bearing mouse tumor. Conclusions : The roots of Agrimonia pilosa Ledebour (APL) contain some antitumor constituents.

• 대한핵의학회지
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• 제19권2호
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• pp.93-95
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• 1985

A simple imaging procedure has been devised for patients with peritoneo-venous shunts when ascites reaccumulates and a decision must be made on whether or not to revise the shunt. We recently experienced a patient with reaccumulated ascites in whom obstruction of peritoneo-venous shunt was suspected. 5 mCi of $^{99m}Tc-phytate$ was injected into the peritoneal cavity and imaging of the abdomen was performed $1\sim30$ minutes later. With a proper funtioning shunt, radioactivity in the liver and spleen were easily identifiable in this case. If the shunt is obstructed, tracer activity will remain in the peritoneal cavity and thus can not be identifiable in the liver or spleen. Conclusively, radionuclide methods might be very useful for evaluation of peritoneo-venous shunt patency.

• International Journal of Aerospace System Engineering
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• 제2권1호
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• pp.58-61
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• 2015

Under the background of combustion instability in solid rocket motor, to study the relationship between pressure oscillations and dynamic process of propellant flames, it is necessary to simulate an oscillation environment with certain frequency, amplitude and duration. This paper presents an experimental installation of pressure oscillation based on pulse-driving technique, with which pressure oscillations features under different pulse-driving conditions were compared and analyzed. For the pulse-driver applied in this paper, a pressure oscillation with 0.15s-0.5s duration, 179Hz-210Hz first order frequency, 0.04MPa-0.35MPa amplitude is simulated. The test results show that an oscillation with higher frequency and lager amplitude can be obtained when pulse-driver is installed on the top of the installation cavity, while on the side, an oscillation with a longer duration and approximate cavity natural frequency can be simulated.

• 한국결정성장학회지
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• 제8권4호
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• pp.550-554
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• 1998

Bridgman-Stockbarger법에서 thermal screen의 역할을 하는 새로운 방법을 6inch 형석(CaF2) 단결정성장을 위하여 고안하였다. 본 방법으로 poly-grain으로의 성장과 내부 cavity, 그리고 solid-liquid(SL) interface를 제어할 수 있었다. Graphite pipe와 ceramic warmer를 사용하여 성장한 6inch의 CaF2 결정은 완전한 단결정으로 성장하였다. 이때의 조건은 2mm/hr의 성장속도, 성장구역에서의 $14^{\circ}C$/cm의 온도구배, 그리고 도가니의 conical tip에서 $1324^{\circ}C$의 온도를 나타내었다. 내부 cavity에 의해 발생되는 light scattering 현상은 성장속도를 감소시키거나 융액을 회전함으로써 제어할 수 있었다.

• 생명과학회지
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• 제28권10호
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• pp.1140-1146
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• 2018

이중탈인산화효소(DUSP)는 성장인자활성 단백질키나제(MAPK)를 조절해서 세포성장과 분화에 관여하며 암, 당뇨병, 면역질환, 신경질환의 신약개발표적이다. DUSP 단백질군에 속하는 DUSP19는c-Jun N-말단 키나제(JNK)를 조절하며 골관절염의 질환화과정에 관여한다. 우리는 야생형 DUSP19 에 비하여 상당히 활성이 증가된 cavity 형성 돌연변이인 DUSP19-L75A의 결정구조를 규명하였다. 결정구조는 Leu75의 곁가지가 없어진 결과로 cavity가 잘 형성되어 있는 것을 보여주며, 활성부위에 결합한 황이온이 회전된 형태로 존재하는 것을 보여준다. Cavity 형성에도 불구하고 cavity를 둘러싸고 있는 잔기들은 그다지 재조정되지 않은 것으로 나타나며 그 대신에 멀리 떨어진 트립토판 잔기가 소수성결합을 강화하고 있는 것으로 나타나서 L75A 돌연변이의 접힘은 cavity 부위의 재조정이 아니라 글로벌 접힘 에너지 최소화 기작에 의해 안정화 되었음을 발견할 수 있었다. 회전된 활성화부위 황이온의 구조는 인산화티로신 잔기와 유사함이 발견되어 L75A 돌연변이가 최적의 활성화형태를 유도했다는 것을 알 수 있었다. 내부 cavity에 의한 활성증가현상과 이에 대한 구조적 정보는 DUSP19의 알로스테릭 조절과 치료제 개발에 정보를 제공한다.