• Title/Summary/Keyword: Intermediate grade

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Fine Needle Aspiration Cytology of Mucoepidermoid Carcinoma of the Salivary Gland (점액표피양 암종의 세침흡인 세포학적 소견)

  • Moon, Jeong-Seok;Oh, Hwa-Eun;Lee, Ju-Han;Kim, Ae-Ree;Kim, Chul-Hwan;Kim, Han-Kyeom;Park, Mee-Ja;Won, Nam-Hee
    • The Korean Journal of Cytopathology
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    • v.8 no.2
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    • pp.135-142
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    • 1997
  • Mucoepidermoid carcinoma is the most common malignant neoplasm of the salivary gland, compring between 30 and 40%. Fine needle apsiration cytology was performed in five patients with mucoepidermoid carcinoma. The patients consisted of three males aged of 42, 48, and 60 years, and two females aged 36, and 56 years. The primary tumor sites were the parotid gland in four patients and the submandibular gland in the rest one. The histologic grades were low in one patient, intermediate in two patients and high in other two. In our experience, the common cytologic findings of low grade subtype were predominent mucous cells with some intermediate cells in an abundant mucinous background. The cytologic findings of intermediate grade subtype were predominant clusters of intermediate cells with or without mucous cells in an abundant mucinous background. And the cytologic findings of high grade subtype were predominant clusters of epidermoid cells with intermediate cells in a bloody background. Cytologic pleomorphism and atypia were more severe in high grade than low and intermediate grade, and nucleoli were more frequently noted in epidermoid cells. In low grade, it is very difficult to decide the benignancy or malignancy of the tumor. In fact, the presence of mucous cells in a mucinous background should rule out any other type of well differentiated carcinoma.

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A CLINICOPATHOLOGIC STUDY ON MUCOEPIDERMOID CARCINOMA OF SALIVARY GLANDS (타액선의 점액유상피암에 관한 임상병리학적 연구)

  • Kim, Jong-Ryoul;Chung, In-Kyo;Sung, Iel-Yong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.23 no.2
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    • pp.174-179
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    • 2001
  • The authors analyzed retrospectively the 19 patients with mucoepidermoid carcinoma of salivary glands who were treated at Department of Oral and Maxillofacial Surgery, Pusan National University Hospital from June, 1986 to September, 1998. The results obtained were as follows: 1. There were 4 males(21%) and 15 females(79%). Age distribution was wide and the mean age was 45.2. 2. Of all mucoepidermoid carcinomas of salivary gonads, 4 cases arose in the major salivary glands and 15 cases in the minor salivary glands. The incidence according to the anatomic primary site for minor salivary glands was 8 cases in the palate, 2 cases each arising in the tongue and floor of mouth and 1 case each arising in the mandible, buccal mucosa and the lower lip. 3. In histopathological classification of mucoepidermoid carcinoma, 5 cases were low grade. 9 cases, intermediate grade and 5 cases, high grade. 4. Perineural invasion was observed 40%(2/5) in high grade and 22%(2/9) in the intermediate grade of mucoepidermoid carcinoma. 5. The incidence of cervical lymph node metastasis according to histopathologic grade was 40% (2/5) in high grade and 11%(1/9) in intermediate grade of mucoepidermoid carcinoma. 6. The lung was the commonest site for metastasis comprising 3 cases among 3 cases of distant spread of which 2 cases in high grade and 1 case in intermediate grade of mucoepidermoid carcinoma.

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Effects of Gamification-Based Learning on Learners' Achievement Motivation at First-Grade Intermediate Level

  • Al-Sulami, Sami Ben Shamlan Bakhit
    • International Journal of Computer Science & Network Security
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    • v.22 no.5
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    • pp.266-276
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    • 2022
  • The study aimed to pinpoint the effects of an educational environment based on gamification on developing achievement motivation among first-grade intermediate students. Using an achievement motivation scale, the study adopted a quasi-experimental design with experimental and control groups. The sample consisted of 52 students selected randomly from the first-grade intermediate students. They were studying in public intermediate schools in Jeddah at the time of this study. They were divided into two groups. The control group (n=24 respondent), and the experimental group (n=28 respondent). The results showed statistically significant differences at the level α ≥ 0.05 between the mean scores of the experimental group and the control group in the posttest of the achievement motivation measurement in favor of the experimental group. The study recommended using gamification in designing computer curricula and courses across educational stages in Saudi Arabia. It also recommends training the computer and information technology teachers on using gamification in their teaching.

The Relationship between the Performance of Sentence Repetition and Sentence Production in School-age Children (학령기아동의 문장따라말하기와 문장산출 능력과의 관계)

  • Heo, Hyun-Sook;Lee, Yoon-Kyung
    • Phonetics and Speech Sciences
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    • v.2 no.1
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    • pp.127-133
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    • 2010
  • The purpose of the present study was to examine the relationship between sentence repetition and sentence production in school-age children. The participants included 120 school-age children through 1st to 6th grades who were then divided into three grade groups (lower grade: 1st to 2nd grades, intermediate grade: 3th to 4th grades, and higher grade: 5th to 6th grades). The repetition task consisted of 32 sentences that were classified by sentence length (5, 6, 7, and 8 words) and structure (conjunctive and embedded sentences). The sentence production task utilized Lee's (2007) grammaticality judgement and sentence combining task. The findings of present study were as follows. (1) The higher grade performed significantly better than the lower and intermediate grades. (2) The participants performed significantly worse when imitating longer sentences than when imitating shorter ones. In addition, there were interaction effects between grade groups and sentences length. (3) The participants performed significantly better when imitating conjunctive rather than embedded sentences. (4) There was significantly positive correlation between the sentence repetition and sentence production task.

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MUCOEPIDERMOID CARCINOMA OF THE MOUTH FLOOR (점액 표피양 암종의 치험례)

  • Son, Yong-Jun;No, Jae-Hyeong;Kho, Young-Gui;Kim, Jong-Ha;Lee, Hee-Chul
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.19 no.1
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    • pp.70-78
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    • 1997
  • Mucoepidermoid carcinoma occurs more freguently than any other in the major sacivary glands. It is relatively more common in parotid than in submandibular gland. Stewart at al published the first large series of these tumors in 1945 and suggested the name "Mocoepidermoid tumor". Now it is divided three categories : low-grade, intermediate-grade, high-grade. And Mucoepidermoid carcinomas are composed of mucous cells, epidermoid cells, and intermediate cells. We freated low-grade mucoepidermoid carcinoma patient with induction chemotherapy, surpery, and adjuvomt chemotherapy.

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Hypofractionated stereotactic body radiotherapy in low- and intermediate-risk prostate carcinoma

  • Kim, Hun Jung;Phak, Jeong Hoon;Kim, Woo Chul
    • Radiation Oncology Journal
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    • v.34 no.4
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    • pp.260-264
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    • 2016
  • Purpose: Stereotactic body radiotherapy (SBRT) takes advantage of low ${\alpha}/{\beta}$ ratio of prostate cancer to deliver a large dose in few fractions. We examined clinical outcomes of SBRT using CyberKnife for the treatment of low- and intermediate-risk prostate cancer. Materials and Methods: This study was based on a retrospective analysis of the 33 patients treated with SBRT using CyberKnife for localized prostate cancer (27.3% in low-risk and 72.7% in intermediate-risk). Total dose of 36.25 Gy in 5 fractions of 7.25 Gy were administered. The acute and late toxicities were recorded using the Radiation Therapy Oncology Group scale. Prostate-specific antigen (PSA) response was monitored. Results: Thirty-three patients with a median 51 months (range, 6 to 71 months) follow-up were analyzed. There was no biochemical failure. Median PSA nadir was 0.27 ng/mL at median 33 months and PSA bounce occurred in 30.3% (n = 10) of patients at median at median 10.5 months after SBRT. No grade 3 acute toxicity was noted. The 18.2% of the patients had acute grade 2 genitourinary (GU) toxicities and 21.2% had acute grade 2 gastrointestinal (GI) toxicities. After follow-up of 2 months, most complications had returned to baseline. There was no grade 3 late GU and GI toxicity. Conclusion: Our experience with SBRT using CyberKnife in low- and intermediate-risk prostate cancer demonstrates favorable efficacy and toxicity. Further studies with more patients and longer follow-up duration are required.

MUCOEPIDERMOID CARCINOMA OCCURRED IN THE HARD PALATE (경구개 부위에 발생된 점막유표피종양)

  • CHOI Eun Suk;KOH Kwang Joon
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.24 no.1
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    • pp.151-159
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    • 1994
  • Authors experienced a case of intermediate grade mucoepidermoid carcinoma in 29-year-old female. The origin of this tumor might be mucus secreting cells of palatal mucous gland. The characteristic features were as follows: 1. In clinical examination, exopytic mass was observed in left hard palate and similar to pleomorphic adenoma. 2. In radiographic findings, destructive changes of left hard palate, nasal septum, nasal inferior turbinate and floor of maxillary sinus and soft tissue mass were observed. 3. Histopathologically, mucus-secreting cells, epidermoid cells and intermediate cells were observed and diagnosed as intermediate grade mucoepidermoid carcinoma.

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The Role of Radiotherapy in Stage I , II Intermediate Grade Non-Hodgkin's Lymphoma (I, II기 Intermediate Grade 임파종에서 방사선 치료의 역할)

  • Yun Hyong Geun;Kim Il Han;Kim Heung Tae;Ahn Yong Chan;Kim Jae Sung;Ha Sung Whan;Park Charn Il
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.103-109
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    • 1991
  • Radiotherapy result of 162 patients with stage I, II intermediate grade non-Hodgkin's Iymphoma was analyzed to clarify the role and limit of radiotherapy. Of 68 initial failures, 38.2% occurred in field and 61.8% occurred out of field. Proportion of in-field and out-of-field failures in stage I was 30.0% and 70.0%, respectively with involved field treatment and was 43.8% and 56.2% with extended field treatment, respectively; in stage ll , was 16.7% and 83.3%, 41.7% and 58.3%, respectively. The disease free suwival rate at S years was 48.1% for all patients and was 50.3% and 40.4% for patients with stage I and II, respectively. The survival was significantly different by stage. Bulky tumors (${\geq}10$ cm) and B symptoms didn't influence prognosis significantly. The 5 year disease free suwival with extended or wide field was better than that with involved field especially in stage I. Overall survival rates for all patients, patients with stage 1, and ll disease were 57.7%, 65.3% and 52.2% , respectively, after survival gain of the salvage chemotherapy was combined. But the overall survival of stage I disease was not better than that of stage II disease. Thus, extended field was required to achieve better disease free survival and relapsed cases might gain with chemotherapy.

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A CASE REPORT OF MUCOEPIDERMOID CARCINOMAS (점막유표피암종의 치험례)

  • Lee, Sang-Chull;Kim, Yeo-Gab;Ryu, Dong-Mok;Oh, Seung-Whan;Yoon, Ok-Byung;Shin, Min-Cheol
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.1
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    • pp.125-134
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    • 1996
  • Mucoepidermoid carcinomas, first reported by Volkman(1895), form 6% to 9% of all salivary tumors. Two thirds affecting the parotid gland and the remaining third, the minor glands. As we could know from its name, mucoepidermoid carcinomas originate from ductal epithelium including squamous, mucous-secreting, and undifferentiated intermediate cells. Histologically, it is classified as well-differentiated (low grade), moderately-differentiated(intermediate grade), and poorly-differentiated (high grade) types and the treatment method and prognosis are influenced from its histological grade. We have experienced two cases of mucoepidermoid carcinoma treated surgically with good results and now would like to report these with review of literatures.

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A Case of Intermediate Grade Bronchial Mucoepidermoid Carcinoma and Review in Korean Cases (중간등급의 기관지 점액표피양 암종 1예와 국내 보고에 대한 고찰)

  • Cha, Sung Chul;Kim, Si Woo;Cho, Yoo Jin;Park, Sung Kyoon;Park, Hyun Keun;Kim, Jong Sang;Kwak, Jae Wook;Yoo, Moon Bin;Cho, Hye Jae;Lee, Jae Jin
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.1
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    • pp.41-48
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    • 2008
  • Bronchial mucoepidermoid carcinoma is uncommon, representing 0.2% of all lung tumors. The disease usually presents with symptoms of airway obstruction and recurrent pneumonia. It is commonly classified into two grades in Korea, low and high. We report a case of a bronchial mucoepidermoid carcinoma in a 40-year-old woman who complained of symptoms of an upper respiratory infection. The histological grade after a bronchoscopic biopsy was intermediate. A left upper lobectomy was performed as treatment. The TNM stage of this case was IA (T1N0M0). In addition, 25 cases of bronchial mucoepidermoid carcinoma from 1984 in Korea are also reviewed from the viewpoint of the relationship between the histological grade, TNM stage and clinical course of the tumor.