• 대한기계학회논문집B
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• 제38권5호
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• pp.423-430
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• 2014

파이프 유동 내에서 일어나는 소음 및 진동현상의 경우 일반적으로 난류유동과 근처의 벽면사이의 유동유기진동에 의해 일어나게 된다. 복잡한 난류유동을 가지는 확장관의 단순한 경우에서 본 연구는 수행되었지만, 방사소음의 경우 주어진 모델에서 크기와 형상 그리고 두께 등에 상당히 영향을 받게 된다. 또한, 방사소음은 그 파가 퍼져나가면서 주위 시스템에 교란특성이나 불안정성을 야기시키게 되는데 결국 중요한 파단과 파손을 일으키게 된다. 본 연구는 다양한 상용프로그램들 (Fluent, NASTRAN, 그리고 VIRTUAL LAB)을 이용하여 이러한 현상을 파악하고자 하였다. 이 연구를 통해 유동소음에 있어 깔려있는 물리현상들을 이해하고자 하였다. 확장관의 경우 단면적의 급격한 변화에 의해 박리와 높은 압력강하를 겪게 되는데, 방사소음의 계산으로 이 방사소음의 크기가 100에서 500Hz영역에서 전체적으로 약 20dB정도 감소시킬 수 있는 것을 확인할 수 있었다.

• 비파괴검사학회지
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• 제28권2호
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• pp.119-124
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• 2008

최근 비파괴 검사를 위한 테라헤르츠 전자기파 기술에 대한 관심이 높아지고 있으며 특히 비파괴검사에서 많은 응용이 기대된다. 테라헤르츠 시간 영역 분광법은 이러한 테라헤르츠 기술에 핵심이 되는 기술로 많은 실험이 이루어지고 있다. 본 논문에서는 테라헤르츠 시간 영역 분광에서 비선형 전광물질을 이용하는 광정류 방식을 통해 발생된 테라헤르츠 전자기파 스펙트럼이 비선형 맥스웰 방정식의 해와 실험에 의해 결정되는 흡수, 회절, 표면간섭 효과 등을 고려한 본문의 모델을 통하여 예측가능하며 실제 티타늄:사파이어 레이저 펄스를 $400{\mu}m$ CdTe에 조사하여 발생된 테라헤르츠파 주파수 스펙트럼의 측정 결과와 비교하여 매우 유사하다는 사실을 보여준다. 이를 통하여 본문에서 소개된 모델은 다른 전광물질을 통해 발생된 테라헤르츠 스펙트럼에도 확장되어 적용 될 수 있다.

• 대한조선학회논문집
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• 제52권6호
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• pp.452-459
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• 2015

It is important to use bench test results in the design process of anti-rolling tanks. Traditional bench tester is usually designed to perform only roll motions about a fixed axis and relatively small so that the viscous effects may not be neglected. Novel bench tester which could adjust the motion center to realize the coupled motion of sway and roll has been devised and manufactured therefore, large scaled bench tester could be utilized for designing the passive anti-rolling tanks. The time history of the reference signal from the rotation sensor of the bench tester have been recorded and processed to determine the phase angle to derive the Response Amplitude Operator(RAO) of the stabilized ship. The breadth of ART tank model should be large up to 2 m to diminish viscous scale effect and the vertical position of the tank can be varied with the ship's center of motion. The periods and the amplitude of roll motion can be varied from 1.5 sec to 5 sec and up to ±20°, respectively. The components of the tester was expressed in three dimensional digital mockup (DMU) and assembled together in the CAD space. The final configuration of the bench tester has been determined by confirming the smooth operation of the moving parts without interference through the animation in CAD space. New analytic logic are introduced for the determination of hydrodynamic moment and phase difference due to fluid motion in ART and verified through the test. The developed bench tester is believed to be effective and accurate for the verification of stabilization effect of ART taking into the consideration of the sway effect in the design stage.

• 한국전자통신학회논문지
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• 제7권2호
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• pp.263-269
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• 2012

CDMA는 여러 사용자가 시간과 주파수를 공유하면서 각 사용자에게 확산코드라고 하는 서로 다른 의사잡음수열(pseudonoise sequence)을 할당한다. 각 사용자는 할당된 확산코드를 이용하여 송신할 신호를 변조한다. 신호를 변조하는데 사용하는 코드를 선택하는 것은 CDMA 시스템의 수행능력을 결정하는 데 있어 매우 중요하다. 왜냐하면 품질이 좋은 수열은 사용자들 사이의 신호들의 간섭을 줄이고 신호를 잘 복호할 수 있도록 하기 때문이다. 수신자는 데이터를 복호하기 위해 수신된 부호를 동기화한다. 서로 독립인 코드를 사용하는 것은 동시 다중접속을 가능하게 한다. 본 논문에서는 확산 스펙트럼 통신에서 다중접속 충돌을 최소화하고, 시스템의 보안을 증가시키고 사용자의 수를 늘이는데 도움을 주는 비선형 수열을 생성하고 상호상관관계를 분석한다.

• 한국초전도ㆍ저온공학회논문지
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• 제15권2호
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• pp.20-23
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• 2013

For sensitive measurements of micro-Tesla nuclear magnetic resonance (${\mu}T$-NMR) signal, a low-noise superconducting quantum interference device (SQUID) system is needed. We have fabricated a liquid He dewar for an SQUID having a large diameter for the pickup coil. The initial test of the SQUID system showed much higher low-frequency magnetic noise caused by the thermal magnetic noise of the aluminum plates used for the vapor-cooled thermal shield material. The frequency dependence of the noise spectrum showed that the noise increases with the decrease of frequency. This behavior could be explained from a two-layer model; one generating the thermal noise and the other one shielding the thermal noise by eddy-current shielding. And the eddy-current shielding effect is strongly dependent on the frequency through the skin-depth. To minimize the loop size for the fluctuating thermal noise current, we changed the thermal shield material into insulated thin Cu mesh. The magnetic noise of the SQUID system became flat down to 0.1 Hz with a white noise of 0.3 $fT/{\surd}Hz$, including the other noise contributions such as SQUID electronics and magnetically shielded room, etc, which is acceptable for low-noise ${\mu}T$-NMR experiments.

• Asian Pacific Journal of Cancer Prevention
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• 제15권7호
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• pp.3045-3050
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• 2014

Renal cell carcinoma (RCC) is the most lethal of all urological cancers and tumor angiogenesis is closely related with its growth, invasion, and metastasis. Recent studies have suggested that epidermal growth factor-like domain multiple 7 (EGFL7) is overexpressed by many tumors, such as colorectal cancer and hepatocellular carcinoma; it is also correlated with progression, metastasis, and a poor prognosis. However, the role of EGFL7 in RCC is not clear. In this study, we examined how EGFL7 contributes to the growth of RCC using a co-culture system in vitro and a xenograft model in vivo. Downregulated EGFL7 expression in RCC cells affected the migration and tubule formation of HMEC-1 cells, but not their growth and apoptosis in vitro. The level of focal adhesion kinase (FAK) phosphorylation in HMEC-1 cells decreased significantly when co-cultured with 786-0/iEGFL7 cells compared with 786-0 cells. After adding rhEGFL7, the level of FAK phosphorylation in HMEC-1 cells was significantly elevated compared with phosphate-buffered saline (PBS) control. However, FAK phosphorylation was abrogated by EGFR inhibition. The average size of RCC local tumors in the 786-0/iEGFL7 group was noticeably smaller than those in the 786-0 cell group and their vascular density was also significantly decreased. These data suggest that EGFL7 has an important function in the growth of RCC by facilitating angiogenesis.

• 대한기계학회논문집A
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• 제25권10호
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• pp.1551-1558
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• 2001

Recently, a number of underground pipelines have been drastically increased. The integrity of these buried pipelines, especially gas transmitting pipelines, is of importance due to an explosive characteristic of natural gas. The third party damage is known as one of the most critical factor which causes fatal accidents. For this reason, a number of systems detecting third party damage are under development. The major concern in the development of third party damage detection system is to transmit vibration signals out of accelerometer to signal conditioner and data acquisition system without any interference caused by noise. The objective of this paper is to develope a fiber optic accelerometer applicable to third party damage detection system. A fiber optic accelerometer was developed by use of combining principles of one degree of freedom vibration model and an extrinsic Fabry-Perot interferometer. The developed fiber optic accelerometer was designed to perform with a sensitivity of 0.06mVg, a frequency range of less than 6kHz and an amplitude range of -200g to 200g. The developed, accelerometer was compared with a piezoelectric accelerometer and calibrated. In order to verify the developed accelerometer, the field experiment was performed. From the field experiment, vibration signals and the location of impact were successfully detected. The developed accelerometer is expected to be used for the third party damage detection system which requires long distance transmission of signals.

• 대한공간정보학회지
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• 제14권2호
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• pp.63-68
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• 2006

광범위한 지역의 자연환경 정보를 파악하기 위하여 위성 영상자료를 이용하는 것이 적합하지만 선행되어야 할 것은 이러한 위성영상자료를 이용하기 위한 지상에서의 내부 실험과 현장실험을 통한 기초적인 모형식을 만드는 것이 중요하다. 이를 위하여 위성영상자료와 실측수질인자들의 상관관계를 조사하는 것이 보다 정확하고 객관적인 평가 방법이 될 수 있다. 따라서 대기의 영향이 없는 실험실내에서 순수한 담수와 해수를 이용하여 Landsat ETM+ 영상자료의 어느 밴드가 클로로필a 농도파악에 적합한가를 평가하고자 하였다. 그 결과 밴드조합 중 가장 높은 상관관계를 보인 최적밴드는 담수에서 (B3-B4)/B2이고, 해수에서는 (B2+B4)/B3로 이 때의 상관계수가 각각 0.9747, 0.9892이다. 따라서 Landsat ETM+ 영상자료를 이용하여 클로로필a 농도 평가 시 이 밴드를 조합하여 사용하는 것이 유효할 것으로 생각된다.

• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2008년도 International Meeting of the Microbiological Society of Korea
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• pp.62-64
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• 2008

A major hurdle to the development of RNA interference as therapy for HIV infection is the delivery of siRNA to T lymphocytes which are difficult cells to transfect even in vitro. We have employed a single chain antibody to the pan T cell surface antigen CD7 was conjugated to an oligo-9-arginine peptide (scFvCD7-9R) for T cell-specific siRNA delivery in NOD/SCIDIL2${\gamma}$-/- mice reconstituted with human peripheral blood lymphocytes (Hu-PBL). Using a novel delivery, we first show that scFvCD7-9R efficiently delivered CD4 siRNA into human T cells in vitro. In vivo administration to Hu-PBL mice resulted in reduced levels of surface CD4 expression on T cells. Mice infected with HIV-1 and treated on a weekly basis with scFvCD7-9R-siRNA complexes targeting a combination of viral genes and the host coreceptor molecule CCR5 successfully maintained CD4/CD3 T cell ratios up to 4 weeks after infection in contrast to control mice that displayed a marked reduction in CD4 T cell numbers. p24 antigen levels were undetectable in 3 of the 4 protected mice. scFvCD7-9R/antiviral siRNA treatment also helped maintain CD4 T cell numbers with reduced plasma viral loads in Hu-PBL mice reconstituted with PBMC from donors seropositive for HIV, indicating that this method can contain viral replication even in established HIV infections. Our results show that scFvCD7-9R could be further developed as a potential therapeutic for HIV-1 infection.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권9호
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• pp.4491-4509
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• 2017

The present paper proposes a novel dynamic system for hand gesture recognition. The approach involved is comprised of three main steps: detection, tracking and recognition. First, the gesture contour captured by a 2D-camera is detected by combining the three-frame difference method and skin-color elliptic boundary model. Then, the trajectory of the hand gesture is extracted via a gesture-tracking algorithm based on an occlusion-direction oriented linear extrapolation predictor, where the gesture coordinate in next frame is predicted by the judgment of current occlusion direction. Finally, to overcome the interference of insignificant trajectory segments, the longest common subsequence (LCS) is employed with the aid of velocity information. Besides, to tackle the subgesture problem, i.e., some gestures may also be a part of others, the most probable gesture category is identified through comparison of the relative LCS length of each gesture, i.e., the proportion between the LCS length and the total length of each template, rather than the length of LCS for each gesture. The gesture dataset for system performance test contains digits ranged from 0 to 9, and experimental results demonstrate the robustness and effectiveness of the proposed approach.