• Proceedings of the PSK Conference
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.241.3-242
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• 2002

Expression of phase II detoxifying genes is regulated by NF-E2-related factor 2 (Nrf2)-mediated antioxidant response element (ARE) activation. Phosphatidylinositol 3-kinase (PI3-kinase) plays an essential role in ARE-mediated rGSTA2 induction by oxidative stress and controls microfilaments and translocation of actin-associated proteins. This study was designed to investigate the P13-kinase-mediated nuclear translocation of Nrf2 and the interaction of Nrf2 with actin. (omitted)

• Proceedings of the KIEE Conference
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• 대한전기학회 1999년도 하계학술대회 논문집 B
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• pp.543-545
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• 1999

In this paper, the composition method of global and local fuzzy reasoning concepts is researched for reducing the number of rules, not losing the performance for fuzzy controller. A new method is proposed in details that controls the interaction between global reasoning and local reasoning. In order to automatically acquire and optimize the method, the DNA coding algorithm is introduced to the local fuzzy reasoning of the proposed composition fuzzy reasoning method. The method is applied to the real liquid level control system for the purpose of evaluating the Performance. The simulation results show that the proposed technique can produce the fuzzy rules with higher accuracy and feasibility than the conventional methods.

• Reproductive and Developmental Biology
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• 제39권1호
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• pp.1-6
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• 2015

Luteolysis is a cyclical regression of the corpus luteum in many non-primate mammalian species. Prostaglandin $F_2{\alpha}$($PGF_2{\alpha}$) from the uterus and ovary induces functional and structural luteolysis in bovine. The action of $PGF_2{\alpha}$ is mediated by $PGF_2{\alpha}$ receptor located on the luteal steroidogenic and endothelial cell membranes. $PGF_2{\alpha}$ plays an important role in regulating nitric oxide production in endothelial cells of the bovine corpus luteum. Nitric oxide production and nitric oxide synthase activity are stimulated and induced by $PGF_2{\alpha}$ in luteal endothelial cells. Moreover, the reactive oxygen species inhibits progesterone secretion in bovine luteal cells and induces apoptosis. Thus, the interaction between $PGF_2{\alpha}$ and reactive oxygen species provides important aspects in physiology of the corpus luteum forfunctional and structural luteolysis.

• The Korean Journal of Zoology
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• 제37권4호
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• pp.592-596
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• 1994

The interaction between fibronectin (FN) and its receptors controls cell attachment and migration, two crucial events during monocyte development and differentiation. To investigate the functional role of FN and its receptor, we have studied adhesion of monocyte to two different regions of FN (38- and 85-kDa domain), as well as the expression of the integrin during monocle differentiation. Anti-integrin Rl subunit antibody completely blocked the attachment of FN-coated latex beads to macrophage, but the effect of anti-integrin u4 antibody was much less significant. Rat monocyte expressed integrin $u4\beta1$ predominantly, while macrophage expressed $\alpha5\beta1$ as analyzed tv flow cvtometer and western blot. From these results, it can be suggested that these two integrins plan different roles during monocyte differentiation.

• Journal of Microbiology
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• 제44권3호
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• pp.311-319
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• 2006

Bud6p is a component of a polarisome that controls cell polarity in Saccharomyces cerevisiae. In this study, we investigated the role of the Candide albicans Bud6 protein (CaBud6p) in cell polarity and hyphal development. CaBud6p, which consists of 703 amino acids, had 37% amino-acid sequence identity with the Bud6 protein of S. cerevisiae. The homozygous knock-out of CaBUD6 resulted in several abnormal phenotypes, such as a round and enlarged cells, widened bud necks, and a random budding pattern. In hypha-inducing media, the mutant cells had markedly swollen tips and a reduced ability to switch from yeast to hypha. In addition, a yeast two-Hybrid analysis showed a physical interaction between CaBud6p and CaAct1p, which suggests that CaBud6p may be involved in actin cable organization, like Bud6p in S. cerevisiae. Taken together, these results indicate that CaBud6 plays an important role in the polarized growth of C. albicans.

• Proceedings of the KIEE Conference
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• 대한전기학회 1998년도 하계학술대회 논문집 A
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• pp.381-383
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• 1998

The dynamics of the interaction between the wheel and rail must be considered when investigating the application of control strategy to a traction motor for high speed railway system. So this paper describes a dynamics model of the wheel rail adhesion characteristics and simple adhesion control strategy. Simulations are performed on the model of korea-high speed railway system using SIMULINK. With simple adhesion control strategy advanced characteristics of the system is showed in aspects of driveability.

• Proceedings of the KIEE Conference
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• 대한전기학회 1998년도 하계학술대회 논문집 C
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• pp.864-867
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• 1998

This is Part I of a two part paper dealing with control design in power systems using the method of normal forms. In stressed power systems, due to the presence of increased nonlinearity and the existence of nonlinear modal interactions. there exist some limitation to the use of conventional linear control design techniques. The objective of this work is to understand the effect of the nonlinear modal interaction on control performance and to develop a procedure to design controls incorporating the nonlinear information. Part II presents the numerical results dealing with the design procedure.

• Journal of Korean Society of Industrial and Systems Engineering
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• 제17권30호
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• pp.25-34
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• 1994

Mental workload has a improtant place in modern work environment such as human-computer interaction. Designing man-machine system requires knowledge and evaluation of the human cognitive process which controls information flow during our works. Many studies estimate reaction time as a index of menatal workload. This paper investigates what reflacts the workload of human information handling when the informations grow its degree. Experiment result introuce the memory time that explain the information-load more sensitive than react time. And react time shows learning effect but memory time does'nt show that effect So it can be concluded that cognitive learning or work schema needs more time to achieve dexterity than motor skill.

• Journal of the Mineralogical Society of Korea
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• 제3권2호
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• pp.89-97
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• 1990

To examine how London energy controls the c-dimensions of phyllosilicates, London energy, as well as Coulomb and Pauli repulstion energy was calculated as a function of d(001) for 1M and d(002) for 2M 1 phyllosilicates. London and Pauli repulstion energy calcualtion use a direct interaction calculation method and Coulomb energy calculation adopts Fourier synthesis method. The energy calculations show that Coulmb and Pauli repulsion energy dominantly control the c-dimensions of phyllosilicates having the interlayer cationss, i.e., the layer charges. On the other hand, if phyllosilicates have no interlayer cations, London energy is solely responsible for holding the layers and maintain the c-dimensions. The significance of London energy in determining the c-dimensions of phyllosislicates de-creases as the layer charge increases. When the layer charge is lower than one equivalent on the basis of Oη(OH)2 formula, London energy plays an important role in determing the c-dimensions. however, if the layer charge is higher than one equivalent, London energy becomes insignifi-cant in determining the c-dimension.

• Applied Science and Convergence Technology
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• 제27권4호
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• pp.75-77
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• 2018

The electrostatic interaction between emerging quantum-confined nanostructures with plasmonic structures is crucial for future biological applications. Water-soluble green fluorescent copper nanoparticles (Cu-NPs) were fabricated. We demonstrate that L-ascorbic acid is considered as a key to precisely control small Cu-NPs and the capability of the surface ligands, while cetyltrimethylammonium bromide is used as a stabilizing agent controls the particle growth, and stabilizes the nanoparticles. Water-soluble green fluorescent Cu-NPs are tunable through modification of the reaction periods.