• Smart Structures and Systems
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• v.8 no.1
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• pp.107-117
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• 2011

Biological sensory systems continuously monitor and analyze changes in real-world environments that are relevant to an animal's specific behavioral needs and goals. Understanding the sensory mechanisms and information processing principles that biological systems utilize for efficient sensory data acquisition may provide useful guidance for the design of smart-sensing systems in engineering applications. Weakly electric fish, which use self-generated electrical energy to actively sense their environment, provide an excellent model system for studying biological principles of sensory data acquisition. The electrosensory system enables these fish to hunt and navigate at night without the use of visual cues. To achieve reliable, real-time task performance, the electrosensory system implements a number of smart sensing strategies, including efficient stimulus encoding, multi-scale virtual sensor arrays, task-dependent filtering and online subtraction of sensory expectation.

• Knowledge Management Research
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• v.3 no.2
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• pp.49-70
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• 2002

The purpose of this study is to investigate the process and its influencing factors of technological capability building in a small and medium-sized capital goods sector. This paper first reviews the influencing factors of accumulating technological capability-technology trajectory, technology sources, technological capability, technological learning, technology strategy, and entrepreneurship. The paper then presents the integrative model of technological capability building. The experience of Mirae Corporation, the first generation of venture company in Korea, is also discussed as a case in point to analyse the process of technological capability building in a small and medium-sized capital goods company. Finally, the implications and limitations of the study arc discussed.

• Animal cells and systems
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• v.11 no.2
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• pp.93-98
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• 2007

Gonadotropin-releasing hormone (GnRH), synthesized in the hypothalamus, plays a pivotal role in the regulation of vertebrate reproduction. Since molecular isoforms of GnRH and their receptors (GnRHR) have been isolated in a broad range of vertebrate species, GnRH and GnRHR provide an excellent model for understanding the molecular co-evolution of a peptide ligand-receptor pair. Vertebrate species possess multiple forms of GnRH, which have been created through evolutionary mechanisms such as gene/chromosome duplication, gene deletion and modification. Similar to GnRHs, GnRH receptors (GnRHR) have also been diversified evolutionarily. Comparative ligand-receptor interaction studies for non-mammalian and mammalian GnRHRs combined with mutational mapping studies of GnRHRs have aided the identification of domains or motifs responsible for ligand binding and receptor activation. Here we discuss the molecular basis of GnRH-GnRHR co-evolution, particularly the structure-function relationship regarding ligand selectivity and signal transduction of mammalian and non-mammalian GnRHRs.

• BMB Reports
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• v.48 no.8
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• pp.429-430
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• 2015

Angiogenesis is a complex process involving dynamic interaction of various cell to cell interactions. Endothelial cell interactions regulated by growth factors, inflammatory cytokines, or hemodynamic stress are critical for balancing vascular quiescence and activation. Yes-associated protein (YAP), an effector of Hippo signaling, is known to play significant roles in maintaining cellular homeostasis. However, its role in endothelial cells for angiogenic regulation remains relatively unexplored. We demonstrated the critical role of YAP in vascular endothelial cells and elucidated the underlying molecular mechanisms involved in angiogenic regulation of YAP. YAP was expressed in active angiogenic regions where endothelial cell junctions were relatively loosened. Consistently, YAP subcellular localization and activity were regulated by VE-cadherin-mediated PI3K/Akt pathway. YAP thereby regulated endothelial sprouting via angiopoietin-2 expression. These results provide an insight into a model of coordinating endothelial junctional stability and angiogenic activation through YAP. [BMB Reports 2015; 48(8): 429-430]

• Animal cells and systems
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• v.8 no.1
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• pp.65-70
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• 2004

Rbm is a male infertility gene located in the AZFb region of the Y chromosome. Expression pattern of Rbm indicates that Rbm is critical for early phase of male germ cell development. It shares strong structural homology with hnRNP G, suggesting a function as an RNA processing factor. In order to gain a clue on the molecular mechanisms of Rbm on male germ cell development, we examined interactions of Rbm with selected proteins in yeast. The results revealed specific interactions between Rbm, hnRNP K and Tra2${\alpha}$. These results suggest that hnRNP K and Tra2${\alpha}$ may be functional partners of Rbm in male germ cells. We propose a model in which hnRNP K may playa role as a platform for Rbm and Tra2${\alpha}$.

• Journal of Information Technology Services
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• v.3 no.1
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• pp.43-61
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• 2004

Recently It becomes a rapidly growing concern to find effective ways of managing IS development projects as the projects increase in many organization. This paper focuses on developing an integrative management framework for IS development project in contingent perspective. The framework is based upon contingent relationship between management dimensions of IS development project and the characteristics of the task replaced or supported by an IS. Management dimensions of IS development consist of mode, content and process. Task characteristics which are considered as contingent variables include project size, unstructuredness level, hierarchical level, interdependence level and system innovativeness level. The data used for validating this conceptual framework are collected from 119 IS development projects in 70 Korean business organizations. One-way ANOVA and T-test are employed to test the hypotheses.

• The Korean Journal of Health Service Management
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• v.5 no.3
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• pp.191-202
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• 2011

The aim of this study was to examine the impact of the participation motivation of hospital volunteers, their awareness of hospital image, hospital management of volunteers, the organizational interpersonal relationship of volunteers and their satisfaction with volunteer activities on the continuance of their volunteer activities. The subjects were 480 volunteers who did volunteer activities in 37 hospitals in Busan, 399 subjects were responsed. This study is meaningful in that unlike relevant earlier studies of medicine, it attempted to make an integrative analysis of the influential factors for volunteer activities continuance and to make use of structural equation, a more advanced analysis technique. Besides, this study gave some suggestions on the customized management of hospital volunteers, its objects and related logical model.

• The Zoological Society Korea : Newsletter
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• v.18 no.2
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• pp.26-32
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• 2001

동물에서 맛을 느끼는 것과 의사소통이 라는 행위는 생명을 유지하는데 있어 매우 중요한 수단이다. 섭취 할 수 있는 것과 먹어서는 안 되는 물질을 가려내고, 위험으로부터 벗어 날 수 있는 정보를 가장 빠르게 전달 할 수 있는 수단이다. 이러한 기능을 가지고 있는 몸 안의 기관으로는 혀가 있는데, 다양한 근육과 신경의 분포를 이용해서 위에서 언급한 기능을 수행하게 된다. 혀의 다양한 기능과 특징적인 구조에도 불구하고 현재까지는 혀의 감각기관으로써의 기능과 구조에 대한 연구가 대부분인 실정이다. 물론 발생학적 측면에서 다양한 접근이 이루어지고 있으나, 이 또한 신경의 분화와 유도에 대해서 초점을 맞추고 있는 것 이 사실이다. 생물학에 있어서 가장 중요한 초점은 항상 그 구조와 기능이지만 이러한 구조와 기능을 보다 정확하게 이해하기 위해서는 발생학적인 측면에서의 접근이 반드시 필요하고, 특히 Epithelium과 Mesenchyme의 interaction으로 생기는 외배엽성 기원 기관의 하나로써 혀의 papillae에 대한 고찰을 하고자 한다 (Jung et al 1998). 또한 현재까지 진행되어진 신경분포와 감각기관으로의 혀의 역할과 발생 과정에 대해서도 알아보고 이러한 현시점의 발생학과 형태학을 이해하는데 필요한 하나의 Model system으로써의 혀에 대해 이야기하고자 한다.

• Journal of the Korean Society of Costume
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• v.61 no.10
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• pp.119-134
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• 2011

The present study proposes and tests an integrative model for global consumers to examine the relation among fashion marketing mix, brand attitude, brand loyalty, and purchase intention in the jeans market. The questionnaire surveys 692 consumers in the United States, China, and France. The statistical analysis methods that are used are as follows: frequency analysis, factor analysis, SEM analysis, and multi-group analysis. The results show that fashionability, perceived quality, and advertising have a direct and also a positive effect on brand attitude; however, advertising didn't have a direct effect on purchase intention. In addition, the results of the SEM analysis show that brand attitude leads to brand loyalty, while also showing a direct and indirect positive effect on purchase intention. Furthermore, the multi-group analysis reveals significant differences in SEM among countries such as the United States, China, and France.

• Animal cells and systems
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• v.2 no.2
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• pp.209-216
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• 1998

The invasion of Ambrosia artemisiifolia in the Ukrainian Carpathians Mts. and the Transcarpathian Plain in Central Europe was reconstructed on the basis of floristic records. The first spontaneous occurrence was dated from the beginning of the 1940s. Within the next 55 year period, the distributional spread speed of the species was of 67.6 $km^2/y$ (by the average data). The occupied area by A. artemisiifolia in the range of the studied areas is about $3716.5km^2$ now. The features of behavior of the invader and the habitat preference were determined. The frequency of occurrence by sociologic-ecological classification was carried out. The generalized model of correlations among the gravitation, the active temperature sum and the disturbance gradients and the frequency of occurrence of the species was presented. The scheme of the invasion stages of A. artemisiifolia is reflected in the population status changes of the species during the areal dynamics.