• Food Science of Animal Resources
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• v.43 no.4
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• pp.594-611
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• 2023

Whey protein (WP) has nutritional value, but the presence of β-lactoglobulin (β-LG) and α-lactalbumin (α-LA) cause allergic reactions. In this study, hypoallergenic whey protein hydrolyate (HWPH) was prepared by decomposing β-LG and α-LA of WP using exo- and endo-type proteases. The enzyme mixing ratio and reaction conditions were optimized using response surface methodology (RSM). Degradation of α-LA and β-LG was confirmed through gel electrophoresis, and digestion, and absorption rate, and immunostimulatory response were measured using in vitro and in vivo systems. Through RSM analysis, the optimal hydrolysis conditions for degradation of α-LA and β-LG included a 1:1 mixture of Alcalase and Prozyme reacted for 10 h at a 1.0% enzyme concentration relative to substrate. The molecular weight of HWPH was <5 kDa, and leucine was the prominent free amino acid. Both in vitro and in vivo tests showed that digestibility and intestinal permeability were higher in HWPH than in WP. In BALB/c mice, as compared to WP, HWPH reduced allergic reactions by inducing elevated Type 1/Type 2 helper T cell ratio in the blood, splenocytes, and small intestine. Thus, HWPH may be utilized in a variety of low allergenicity products intended for infants, adults, and the elderly.

• Journal of The Korean Association For Science Education
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• v.6 no.2
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• pp.43-52
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• 1986

It is the purpose at thus survey to get hold at problems in teaching integrated science in middle school. For this purpose, problems and suggestions were collected by questionnaire which were made out by middle school science teachers. Through the analysis of the questionnaire, it was found that the present curriculum of science education in the college of education and the in-service training program were not suitable for training middle school science teacher. Form the results of the analysis, this survey concluded that the curriculum and program mentioned above need improvement as follows. (1) science education curriculum in the college of education should be set up with two part. One is the part that middle school science teachers are trained and the other is the part that high school science teachers are trained. (2) In-service training program should be set off into two kinds. One is the program that middle school science teachers are trained and the other program that high school science teachers are trained.

• Journal of radiological science and technology
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• v.28 no.3
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• pp.193-201
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• 2005

We are living in Ubiquitous society now. There is also trend of integration in medical field that is largely affected by outside environment. At this time, it is necessary to rightly understand the abstract, function, expected effect and management method of Integration Medical Information System(IMIS) to use this system effectively for solving many hospital information system problems and disadvantages. It is fact that large-sized hospitals are improving the quality of service for treatment of patients through building integrated Medical Information System. So it is necessary to change this individual system that is previously developed and used for treatment assistance, hospital affair or general management respectively to integrated management system, modify patient information or treatment information data to the data suitable for new system and build the integrated medical information system suitable for the hospital service with treatment data and integrated medical information. This paper suggested and designed abstract of integrated medical information system, the organization of system, the character of system and the plan and materialization of IMIS when building integrated medical information system. And the context of this paper is suggested trend of industry and solution of integration EMR, HIS, PACS. Therefore this paper is suggested development strategy, implemented integration medical information system.

• Journal of The Korean Association For Science Education
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• v.39 no.4
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• pp.545-562
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• 2019

The purpose of this study is to develop cognitive scaffolding tools and to explore their effects on integrated science process skills of high school students. For this purpose, we developed cognitive scaffolding tools including one kind of classroom instruction for training integrated process skills and two kinds of individual learning materials that students can selectively study according to their level of inquiry ability. In addition, we developed hypothetico-deductive inquiry tasks as a tool to investigate the level of students on the integrated process skills for pre-test and post-test respectively. In order to verify the effectiveness of the cognitive scaffolding tools, we conducted inferential statistics on the pre-and post-tests of the experimental group and control group to examine statistical significance of students' inquiry level change depending on the usage of the cognitive scaffolding tools. We also produced Wrightmaps based on Rasch model to compare the change of inquiry ability depending on usage of the cognitive scaffolding tools. As a result, the experimental group using the cognitive scaffolding tools showed a significantly higher scores in all the components of integrated process skills namely, designing inquiry, collecting data, analyzing data, and forming conclusion than the control group. In addition, students who used cognitive scaffolding tools improved their inquiry ability and showed a distinct transition to higher level in each component of the integrated process skills. The results of this study suggest that high school students need cognitive scaffolding to alleviate or eliminate the functional barriers they face in conducting scientific inquiries.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.6
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• pp.2546-2566
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• 2016

This paper investigates an efficient transmission scheme for the remote wireless sensors to receive information which is rarely discussed in the integrated remote wireless sensor and multibeam satellite networks (IWSMSNs). The networks can be employed to exchange sensing information for emergency scenario, ocean scenario, and so on, which are isolated from available terrestrial networks. As the efficient transmission link is important to the IWSMSNs, we propose a hybrid full frequency (HFF) precoding by taking advantage of frequency reuse and multiple-input multiple-output (MIMO) precoding. Considering energy efficiency and sinks fairness are crucial to transmission link, thus the HFF precoding problems are formulated as transmit power minimization (TPM) and max-min fair (MMF) received signal to interference plus noise ratio (SINR) problems, which can be transformed to indefinite quadratic optimization programs. Then this paper presents a semi-definite programming (SDP) algorithm to solve the problems for the IWSMSNs. The promising potential of HFF for the real IWSMSNs is demonstrated through simulations.

• The Journal of Korean Association of Computer Education
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• v.15 no.2
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• pp.67-73
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• 2012

The analytical experiments for fluid dynamics lead a sequence of complex scientific computations composing of numerical equations and require enormous computing resources with appropriate management tools. Currently most studies on e-Science environment for numerical studies focus on solving specific problems to drag out the best performance of matters and have less interest in providing a common framework to apply for diverse numerical domains in engineering education, especially for fluid dynamics. This paper presents an integrated e-Science experiment tool which could be easily applicable to solve various numerical analyses in fluid dynamics. As a proof-of-concept, an integrated e-Science framework with three numerical analyses has been designed and implemented over UNICORE that runs over grid computing environment.

• Macromolecular Research
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• v.11 no.5
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• pp.341-346
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• 2003

A poly(ethylene oxide)-b-poly(L-lactide) diblock copolymer (PEO-b-PLLA) is characterized by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and a block length distribution map is constructed. Although the MALDI- TOF mass spectrum of PEO-b-PLLA is very complicated, most of the polymer species were identified by isolating the overlapped isotope patterns and by fitting the overlapped peaks to the Schulz-Zimm distribution function. Reconstructed MALDI-TOF MS spectrum was nearly identical to the measured spectrum and this method shows its potential to be developed as an easy and fast analysis method of low molecular weight block copolymers.

• Journal of Environmental Science International
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• v.24 no.3
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• pp.303-316
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• 2015

The relationship between urban spatial structures and GHG-AP integrated emissions was investigated by statistically analyzing those from 25 administrative districts of Seoul. Urban spatial structures, of which data were obtained from Seoul statistics yearbook, were classified into five categories of city development, residence, environment, traffic and economy. They were further classified into 10 components of local area, population, number of households, residential area, forest area, park area, registered vehicles, road area, number of businesses and total local taxes. GHG-AP integrated emissions were estimated based on IPCC(intergovernmental panel on climate change) 2006 guidelines, guideline for government greenhouse inventories, EPA AP-42(compilation of air pollutant emission factors) and preliminary studies. The result of statistical analysis indicated that GHG-AP integrated emissions were significantly correlated with urban spatial structures. The correlation analysis results showed that registered vehicles for GHG (r=0.803, p<0.01), forest area for AP (r=0.996, p<0.01), and park area for AP (r=0.889, p<0.01) were highly significant. From the factor analysis, three groups such as city and traffic categories, economy category and environment category were identified to be the governing factors controlling GHG-AP emissions. The multiple regression analysis also represented that the most influencing factors on GHG-AP emissions were categories of traffic and environment. 25 administrative districts of Seoul were clustered into six groups, of which each has similar characteristics of urban spatial structures and GHG-AP integrated emissions.

• International Journal of Computer Science & Network Security
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• v.21 no.7
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• pp.125-132
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• 2021

Rapid growth of the higher education role in ensuring the socio-economic and innovative development of the national economy in the context of the development of the information society and the knowledge economy is observed. Achieving positive synergistic effects of the higher education development requires proper funding for university education and research. The existing funding models for national higher education systems in a number of developing countries need modernization in accordance with the modern challenges of economic and innovative development. The purpose of the article is to formulate theoretical - methodological and applied foundations for the development and implementation of the integrated model of the higher education financing under the Quadruple Helix concept. At the center of the developed model are the areas of interaction identified by the authors, namely: Personnel, Science, Management, Innovation, Social area. This made it possible to specify the interests of all stakeholders and orient the activities of higher education institutions to the satisfaction of these interests. Effective implementation of the integrated Model of the higher education financing requires increasing the level of investment attractiveness and practical value of university research; activation of innovative development of enterprises; state stimulation of business participation in university research and education; harmonization of current legislation with EU standards. Implementation of the Model will diversify sources of funding for universities, increase their level of economic security and achieve integrated synergies from the interaction of universities, business, government and the public (as the main stakeholders within the Quadruple Helix concept).

• Smart Structures and Systems
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• v.23 no.6
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• pp.695-702
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• 2019

The number of cable-stayed bridges has been increasing worldwide, causing issues in maintaining the structural safety and integrity of bridges. The stay cable, one of the most critical members in cable-stayed bridges, is vulnerable to wind-induced vibrations owing to its inherent low damping capacity. Thus, vibration mitigation of stay cables has been an important issue both in academia and practice. While a semi-active control scheme shows effective vibration reduction compared to a passive control scheme, real-world applications are quite limited because it requires complicated equipment, including for data acquisition, and power supply. This study aims to develop an Arduino-based integrated cable vibration control system implementing a semi-active control algorithm. The integrated control system is built on the low-cost, low-power Arduino platform, embedding a semi-active control algorithm. A MEMS accelerometer is installed in the platform to conduct a state feedback for the semi-active control. The Linear Quadratic Gaussian control is applied to estimate a cable state and obtain a control gain, and the clipped optimal algorithm is implemented to control the damping device. This study selects the magnetorheological damper as a semi-active damping device, controlled by the proposed control system. The developed integrated system is applied to a laboratory size cable with a series of experimental studies for identifying the effect of the system on cable vibration reduction. The semi-active control embedded in the integrated system is compared with free and passive mode cases and is shown to reduce the vibration of stay-cables effectively.