• Journal of Information Technology Applications and Management
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• 제15권1호
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• pp.83-97
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• 2008

Today's competitive global market makes most enterprise endeavor to specialize their business areas, and co-operate with trading partners in supply chain by the forms of collaboration, information and business process sharing. However, even the supply chain plan generated by co-operation often fails to be executed successfully, because it was generated without capacities of suppliers and more over nested suppliers. To overcome this limitation, the supply chain plan of an enterprise should be generated truly integrated way. In this paper, we classify business patterns based on scenarios about quotation processing and supply chain planning in self-integrated environment. And we present business process models about four business patterns and describe them, which are classified by whether request for quotation includes information about price, required time periods, and quantity for each required time period and whether it is received from customer or sent to supplier. In addition, we describe the types of supply chain planning problem.

• 한국도서관정보학회지
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• 제39권3호
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• pp.73-94
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• 2008

도서관은 우리나라 국민들이 가장 많이 이용하는 문화시설이며 통합형 문화예술교육 프로그램을 가장 잘 수행할 수 있는 최적의 장소이다. 본 연구는 국내.외 도서관 문화예술교육 프로그램 현황을 분석하여 도서관에서의 문화예술교육 프로그램의 지향할 바와 통합형 문화예술교육 프로그램 모형을 개발하는데 목적을 두고 있다. 통합형 문화예술교육 프로그램의 기본 방향은 현행 학교 및 사교육시장에서 수행되어져 오는 문화예술교육과는 차별화된 도서관의 본질에 충실한 문화예술교육이 이루어지게 하는데 지향점을 두었다. 또한 통합형 문화예술교육 프로그램의 모형안은 체험-이해-소통을 중심으로 제시하였으며, 문화기반시설과 연계한 문화예술교육 프로그램도 제시하였다.

• 소성∙가공
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• 제19권8호
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• pp.474-479
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• 2010

Newly suggested hybrid LED package can reduce the number of LED processes and enhance light efficacy in virtue of its integrated optical patterns. Square-type pyramid pattern was chosen for the integrated optical pattern in this study, and it was proved that the pattern enhances illuminance about three times and luminance about two and half times by optical simulation. Square-type pyramid patterns of 0.02mm height and 0.04mm pitch were successively machined on a copper mold which is necessary for imprinting the integrated pattern. Hybrid LED package with integrated optical pattern will be manufactured with ultra-fine machined mold in future study.

• PNF and Movement
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• 제13권2호
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• pp.89-93
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• 2015

Purpose: This study aimed to verify the effect of integrated patterns (IPs) of PNF on individuals with malalignment using upper extremity and lower extremity patterns simultaneously. This information was then compared to the effect of bowling exercises on malalignment. The study population included individuals in their twenties with malalignment in their posture. Methods: Individuals with malalignment (40 participants in total) were divided into 2 groups based on trunk inclination and side deviation. In one group, IPs of PNF were used as interventions, while the other group used bowling exercises. This process was completed over the course of four weeks. The IP group used two patterns simultaneously: flexion-adduction-external rotation and extension-abduction-internal rotation. These patterns were used in the upper and lower extremities and were crossed diagonally. Results: The trunk inclination decreased in the IP and the bowling group. In the IP group, the degree of inclination decreased from 0.94 to 0.33. The side deviation also decreased to 1.53 (p < 0.05). In the bowling group, the two measured values decreased significantly (p < 0.05). Conclusion: Compared to the bowling exercises used in the bowling group, the results of this study indicate that the use of IPs had a significant effect on trunk inclination and side deviation for malalignment posture patients. Individuals can easily improve malalignment using IPs of PNF (for example, at home or at their office), which suggests that they are not required to seek assistance from a fitness or bowling center, which may save them time.

• 한국지구과학회지
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• 제41권1호
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• pp.48-60
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• 2020

이 연구의 목적은 집단중심 추세모형을 적용하여 과학고 학생들이 탐구를 수행하는 과정에서 나타난 통합 탐구 기능 변화의 양상과 특징을 분석하는 것이다. 이를 위해 3개의 가설-연역적 탐구 과제를 이용하였으며, 이를 59명의 과학고 학생들에게 순차적으로 수행하게 하고 그 과정을 보고서로 작성하게 하였다. 작성된 보고서는 Lee and Park(2017)에 의해 개발된 평가 준거틀에 따라 통합 탐구 기능 4개 요소별로 평가하였으며, 이를 집단중심 추세모형에 적용하여 탐구 과제를 수행한 3개 시점에 따른 탐구 기능 수준의 변화 양상을 요소별로 분석하였다. 또한, 탐구 기능 변화에서 나타난 특징을 몇 가지 관점에서 분석하였다. 연구 결과는 다음과 같다: 첫째, 집단중심 추세모형을 적용하여 학생들의 통합 탐구 기능 변화 양상을 분석한 결과, 4개 요소 모두에서 2개 집단으로 분류되었으나 그 변화 양상은 요소별로 많은 차이가 있었다. 둘째, 학생들의 통합 탐구 기능 변화에서 나타난 특징을 분석한 결과, 탐구 기능의 맥락의존성, 탐구 기능 발달 경로의 변이성, 탐구 기능 요소별 수준의 들쭉날쭉성을 발견할 수 있었다. 연구 결과를 토대로 과학고 학생들의 통합 탐구 기능 발달을 위한 제언을 하였다.

• Journal of Microbiology and Biotechnology
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• 제16권1호
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• pp.141-144
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• 2006

An antibody layer was fabricated to detect Escherichia coli O157:H7. The micropattern of 16-mercaptohexadecanoic acid (16-MHDA) as alkylthiolate was formed on the gold surface by using the PDMS stamp with microcontact printing $({\mu}CP)$ techniques. In order to form antibody patterns on the template, protein G was chemically bound to the 16-MHDA patterns, and antibody was adsorbed on a self-assembled protein G layer. The formation of the 16-MHDA micropattern, self-assembled protein G layer and antibody pattern on Au substrate was confirmed by surface plasmon resonance (SPR) spectroscopy. Finally, the micropatterning method was applied to fabricate the antibody probe for detection of E. coli O157:H7, and monitoring of antigen by using this probe was successfully achieved.

• Genomics & Informatics
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• 제14권2호
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• pp.46-52
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• 2016

Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of epigenetic changes on cancer is still elusive. In this study, we analyzed DNA methylation data on colon cancer taken from The Caner Genome Atlas. We found that several promoters were significantly hypermethylated in colon cancer patients. Through clustering analysis of differentially methylated DNA regions, we were able to define subgroups of patients and observed clinical features associated with each subgroup. In addition, we analyzed the functional ontology of aberrantly methylated genes and identified the G-protein-coupled receptor signaling pathway as one of the major pathways affected epigenetically. In conclusion, our analysis shows the possibility of characterizing the clinical features of colon cancer subgroups based on DNA methylation patterns and provides lists of important genes and pathways possibly involved in colon cancer development.

• 대한교통학회지
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• 제8권1호
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• pp.41-54
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• 1990

The rapid increase in the freight movement in Korea demands the improvement of the freight transportation system both in quantity and in quality. In recent studies integrated freight terminals have been suggested as the most relevant physical facility that solves this problem. This paper is aiming at the efficiency of the freight transportation system in Korea via integrated freight terminals. We develop a mixed integer programming model to determine simultaneously the most efficient freight flow patterns as well as the optimal locations and sizes of the integrated freight terminal facilities. The results of the model implication is also presented.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2003년도 춘계학술대회 논문집
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• pp.196-200
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• 2003

To fulfill the railroad station's duties efficiently, it is essential to view passenger transfer system within the railroad station and in the vicinity of railroad station in the context of broader technological developments in easy access to railroad station. To do the direct service to local station or easy transfer to other mass transportation modes, necessary courses for local govemments and each transportation agency involvement should be taken and long-term integrated transfer strategy must be found. The research designed here was designed to derive a general overview of the integrated transfer patterns with an emphasis on passenger intermodal transportation system.

• 생태와환경
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• 제50권4호
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• pp.478-482
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• 2017

In order to identify key nations and bird species of conservation concern we described multinational collaborations as defined using network analysis linked by birds that are found in all nations in the network. We used network analysis to assess the patterns in bird occurrence for 10,422 bird inventories from 244 countries and territories. Nations that are important in multinational collaborations for bird conservation were assessed using the centrality measures, closeness and betweenness centrality. Countries important for the multinational collaboration of bird conservation were examined based on their centrality measures, which included closeness and betweenness centralities. Comparatively, the co-occurrence network was divided into four groups that reveal different biogeographical structures. A group with higher closeness centrality included countries in southern Africa and had the potential to affect species in many other countries. Birds in countries in Asia, Australia and the South Pacific that are important to the cohesiveness of the global network had a higher score of betweenness centrality. Countries that had higher numbers of bird species and more extensively distributed bird species had higher centrality scores; in these countries, birds may act as excellent indicators of trends in the co-occurrence bird network. For effective bird conservation in the world, much stronger coordination among countries is required. Bird co-occurrence patterns can provide a suitable and powerful framework for understanding the complexity of co-occurrence patterns and consequences for multinational collaborations on bird conservation.