• The Korean Journal of Physiology and Pharmacology
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• v.18 no.1
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• pp.73-78
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• 2014

Cell death and survival are tightly controlled through the highly coordinated activation/inhibition of diverse signal transduction pathways to insure normal development and physiology. Imbalance between cell death and survival often leads to autoimmune diseases and cancer. Death receptors sense extracellular signals to induce caspase-mediated apoptosis. Acting upstream of CED-3 family proteases, such as caspase-3, Bcl-2 prevents apoptosis. Using short hairpin RNAs (shRNAs), we suppressed Bcl-2 expression in Jurkat T cells, and this increased TCR-triggered AICD and enhanced TNFR gene expression. Also, knockdown of Bcl-2 in Jurkat T cells suppressed the gene expression of FLIP, TNF receptor-associated factors 3 (TRAF3) and TRAF4. Furthermore, suppressed Bcl-2 expression increased caspase-3 and diminished nuclear factor kappa B (NF-${\kappa}B$) translocation.

• Journal of Wetlands Research
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• v.7 no.1
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• pp.93-106
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• 2005

This article is based on the findings of problems and limits in implementing integrated coastal management strategy in Shihwa Lake area to develop management framework, mechanisms and processes that insure the participation of various stakeholders in making decisions for sustainable development of reclaimed land. The project performance of the Shihwa Comprehensive Management Plan for Water Quality and Environment Restoration formulated in 2001 was evaluated and reviewed to give some valuable guidance for reducing the wide gap between integrated planning and implementation. Managing inter-sectoral conflicts among future land uses in Shihwa reclaimed area is one of the most important issues to make progress in integrated coastal management. There is a urgent need of developing scientific decision-supporting tools for evaluating the alternative scenarios as well as capacity building programs for local stakeholders.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.545-552
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• 2008

To insure the quality and safety of ground anchors, pull-out test of anchor has to be done. In the individually controlled pull-out test system, pull-out device is used to introduce the same pull-out force to individual tendon that has a different length and a deflection. That is, that device has a separate pull-out oil jack to each tendon, thus the pull-out length of each jack is not the same, but that device introduces each tendon to the same pull-out force. In this study, the in-situ pull-out tests for the compression anchors were performed and its test results were analysed and compared to the results of center hole pull-out tests. In the case of pulling out each tendon using the individually controlled pull-out test device, the pull-out forces were distributed to a individual tendon. That device is excellent one that can solve the cause of unequal pull-out forces of each tendon appearing in the manufacture process and construction of anchors, and unequal pull-out forces due to the deferent length.

• Proceedings of the Korea Information Assurance Society Conference
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• 2004.05a
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• pp.85-90
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• 2004

Web service technology will be used in various business fields and it will affect business paradigms. But, however, there is no standard so far and we have many problems to be solved in order to insure interoperability and security. Especially we have to solve Web service security for effective utilization of the technology and otherwise, the technology will not be used in the business field. We, therefore, need to develope security technology which fits to the Web service characteristics. This document describes a proposed strategy for addressing security within a Web service environment based on the results of analysis on the Web service security problems.

• Journal of Technologic Dentistry
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• v.20 no.1
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• pp.91-98
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• 1998

Bonded lingual retained are divided into two common types; preformed retainers with attached mash pads, and those that are custom fabricated from standard round ir multi-standed wire. The clinician may encounter problems in the bonding process of both types of retainers because of an inability to accurtely place and temporarily stability the wire in the same position as it was adapted an a guide model. Because of these problems, a new fabrication technique of bonded lingual retainers which increase their accuracy and ease of placement and also increased their tretention was suggested by the author. Using a current model as a guide, this bonded lingual retainer was fabricated from $.028"{\sim}.032"$ standard round wire. The wire was formed with pliers for idel adapation to the lingual surfaces of the involved teeth. Right angle bends were placed in the retainer wire ends and custom "composite" bonding pads were added to the ends of the retainer wire. This bonded lingual retainer with custom "composite" bonding pads is easir to place because of the increased stability and the accuracy of placement is greatly increased. The increased insure that the retainer comforms ideally to the lingual surface of the teeth being retained.

• Journal of the Korean Institute of Educational Facilities
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• v.17 no.3
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• pp.3-11
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• 2010

This survey study aims to explore the school area standards for elementary, middle and high schools. Traditionally the school site has been recognized as a space of teaching and learning for students. Though its functions and needs have recently been changing from the areas for physical education and training to for various activities such as recreation, play, communication, informal and social areas etc. Moreover the school site is also a critical component of community life. Many communities have a significant shortfall in the amount of park and open space land available and accessible for use. In this viewpoint the standards of school facilities should develop a comprehensive approach to insure that students and residents are provided the opportunity to engage in appropriate types and amounts of everyday's activities during the school day and after school. In doing so, it surveys the school areas of the existing schools and the new schools built in Dongtan City. Finally, it points out the problems of government's regulation for school facilities and proposes the adequate directions for school area standards. This study would help to plan the optimum size of school area and ground and the reasonable expenditure for school facilities.

• Journal of the Korea Convergence Society
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• v.8 no.5
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• pp.155-160
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• 2017

A cabin of the agricultural tractor is designed to protect the driver from vibration transmitted due to the irregular ground and overturning of the tractor. The cabin is usually manufactured by welding frames and plates. Consequently, the welded state of the frame and plate affects the stiffness of the cabin structure. In this paper, the static and dynamic stiffness characteristics of the cabin are identified through finite element analysis and effects of the structure production error are investigated to insure the structural stiffness of the cabin.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.2076-2082
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• 2003

A cross-flow fan is widely used on many industrial fields: mining industry, automobile and home appliances, etc. The design point of the cross-flow fan is generally based on the region within low static pressure and high flow rate. It relatively makes high dynamic pressure at low speed because a working fluid passes through an impeller blade twice. However, it has low static pressure efficiency between 30% and 40% because of relative high impact loss. Recently, in the air-conditioning systems, the operating behaviors at the off-design points are highly regarded to broaden the application area for various air-cooling loads. Especially, at the lower flow rate, there exists a rapid pressure head reduction, a noise increase and an irregular flow field against a rearguider as a scroll of centrifugal fan. Numerical analyses are carried out for investigating the flow characteristics in a cross-flow fan including the impeller, the rearguider and the stabilizer. Especially, various types of rearguiders are estimated by numerical and experimental methods to insure the stable operation in the region of lower flow rate. Numerical domains are discretized by hexahedral cells. Three-dimensional, unsteady governing equations are solved using FVM, PISO algorithm, sliding grid system and standard ${\kappa}-{\varepsilon}$ turbulence model. ASHRAE standard fan tester is also used to estimate the performance of the modeled crossflow fan.

• Journal of Korean Society of Forest Science
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• v.10 no.1
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• pp.1-3
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• 1970

It is quite difficult to analyse the profit that can be obtained from tree plantations because very many factors are involved. However, for giving sound guidelines to forestry enterprices, it is beneficial in calculating the cost ratios. The present author has made some predetermined assumptions for this calculation relating to larch plantations. According to the results, to insure a sound enterprice, the rate of the annual compound interest should be less than 8 percent taking into consideration the risk ratio. It is true, however, that we do not always depend only upon profit analysis results in forest management.

• Journal of the Korean Professional Engineers Association
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• v.15 no.3
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• pp.49-60
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• 1982

In Korea small-medium companies constitute 96.7% of all of the mining and manufacturing industries, about 34.2% of the total production of value added business, an average of 34.8% of #he actual export of industrial goods, and 49.4% of employment at the end of 1980. Now then small-medium industry companies organization style constitutes 82.1% of private companies and 82.7% of the total on an small scale under 49 persons in regular empolyees. Small-medium industry Companies have growing problems and bottle-necks in their physical conditions. Total Quality Control is contributed by small-medium industry company for more growth than present conditions. But now, Small-medium industry company do not use systematic application of Quality Control Method, the small-medium business company products quality is not better as compared with big business company. Specially, TQC is needed for Small-medium company for imperishable enlargement . In order to promote good will and the major stress of this paper is first of all on the problems of Quality Control, which covers the present states and derived problems of Quality Control, ill Korea Small-medium industry Companies. These are investigated and analyzed to insure the rational application of Quality Control to the Small-medium companies with a view of the establishment of the direction and systematic improving means of Quality Control application Model building for Korea Small-medium industry.