• Genomics & Informatics
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• 제12권3호
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• pp.80-86
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• 2014

Foldback intercoil (FBI) DNA is formed by the folding back at one point of a non-helical parallel track of double-stranded DNA at as sharp as $180^{\circ}$ and the intertwining of two double helixes within each other's major groove to form an intercoil with a diameter of 2.2 nm. FBI DNA has been suggested to mediate intra-molecular homologous recombination of a deletion and inversion. Inter-molecular homologous recombination, known as site-specific insertion, on the other hand, is mediated by the direct perpendicular approach of the FBI DNA tip, as the attP site, onto the target DNA, as the attB site. Transposition of DNA transposons involves the pairing of terminal inverted repeats and 5-7-bp tandem target duplication. FBI DNA configuration effectively explains simple as well as replicative transposition, along with the involvement of an enhancer element. The majority of diverse retrotransposable elements that employ a target site duplication mechanism is also suggested to follow the FBI DNA-mediated perpendicular insertion of the paired intercoil ends by non-homologous end-joining, together with gap filling. A genome-wide perspective of transposable elements in light of FBI DNA is discussed.

• 식물조직배양학회지
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• 제22권4호
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• pp.201-205
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• 1995

Nopaline synthase promoter의 upstream element region을 본딴 nos-RP 요소라고 불리워진 합성 oligomer는 nos wild type promotor의 5' end에서부터 - 101까지를 절단한 promoter의 upstream에 삽입하였다. Nos promoter의 활성은 nos promoter와 연결되어 있는 reporter gene인 Chlorarnphenicol과 $\beta$-glucuronidase유전 인자들이 발현되는 현상을 연구함으로써 측정하였다. 형질 전환된 유전인자를 가지고 있는 담배 식물에 대한 분석은 nos minimal promoter의 활성이 합성 nos-RP 요소가 삽입됨으로써 회복될 수 있음을 보여 주었다. 또한 Nos minimal promoter의 upstream에 nos-RP 요소의 삽입은 여러 가지 환경적인 요소들인 auxin, dithiothreitol, salicylic acid 그리고 methyl jasmonate에 의해서 활성이 증가됨을 보여 주었다.

• Parasites, Hosts and Diseases
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• 제42권3호
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• pp.145-148
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• 2004

We compared the DNA sequence difference of isolates of Clonorchis sinensis from one Korean (Kimhae) and two Chinese areas (Guangxi and Shenyang), The sequences of nuclear rDNA (18S, internal transcribed spacer 1 and 2: ITS1 and ITS2) and mitochondrial DNA (cytochrome c oxidase subunit 1: cox1) were compared. A very few intraspecific nucleotide substitution of the 18S, ITS1, ITS2 and cox1 was found among three isolates of C. sinensis and a few nucleotide insertion and deletion of ITS1 were detected. The 18S, ITS1, ITS2 and cox1 sequences were highly conserved among three isolates. These findings indicated that the Korean and two Chinese isolates are similar at the DNA sequence level.

• 산업경영시스템학회지
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• 제21권48호
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• pp.279-289
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• 1998

This study deals with the schemes of design, plan and operate maintenance management support systems and with the engineering approach for the solutions to build the maintenance management for the production efficiency. Maintenance Management Information System(MMIS) is the task that must focus on machinery historical data and planned maintenance action. Also the efficient supporting system in a maintenance management is achieved by database which is based on process of machinery's failure history. Designing method of maintenance management information system, maintenance modules are consisted of six factors ; machinery's historical data, lubrication control, check sheet, repair work, availability report, and performance report(control board and detailed reports), and then operators can rapidly utilize data in work place. In the implementation of designed model, program coding has been developed by Visual Basic 3.0. Data insertion, deletion and updating which perform menu screen is implemented by reading data from database. Implementation model based on LAN environment and related data is stored in Microsoft DBMS.

• Journal of Veterinary Science
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• 제19권6호
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• pp.855-857
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• 2018

Porcine parvovirus 7 (PPV7) was first detected in Korean pig farms in 2017. The detection rate of PPV7 DNA was 24.0% (30/125) in aborted pig fetuses and 74.9% (262/350) in finishing pigs, suggesting that PPV7 has circulated among Korean domestic pig farms. Phylogenetic analysis based on capsid protein amino acid sequences demonstrated that the nine isolated Korean strains (PPV-KA1-3 and PPV-KF1-6) were closely related to the previously reported USA and Chinese PPV7 strains. In addition, the Korean strains exhibit genetic diversity with both insertion and deletion mutations. This study contributes to the understanding of the molecular epidemiology of PPV7 in Korea.

• Animal cells and systems
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• 제7권3호
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• pp.249-253
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• 2003

Abnormalities in fibrinolysis system is associated with risk of hypertension. In this report, the Alu repeat insertion/deletion (I/D) polymorphism of tissue plasminogen activator (t-PA) and the Hind III RFLP of plasminogen activator inhibitor-1 (PAI-1) genes were investigated in 115 normotensives and 83 patients with hypertension, and their association with anthropometrical data and plasma biochemical parameters were analyzed. There were no significant differences in the gene frequencies of the two candidate genes between normotensives and hypertensives, respectively. Our results indicate lack of associations between the two polymorph isms in t-PA and PAI-1 genes and risk of hypertension in the population under study. However, the Hind III RFLP of PAI-1 gene was significantly associated with plasma glucose level, suggesting its role in glucose metabolism. It needs to be tested whether this RFLP of PAI-1 gene is associated with insulin resistance syndrome or non-insulin dependent diabetes mellitus (NIDDM) in the Korean population.

• 한국전자거래학회지
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• 제1권1호
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• pp.173-194
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• 1996

In order to adapt today's short product life cycle and rapid technology changes., integrated systems should be extended to support PDM (Product Data Management) or CE(Concurrent Engineering). A PDM/CE environment has been developed and a prototype is Presented in this paper. Features of the PDM/CE environment are 1) integrated product information model (IPIM) includes both data model and integrity constraints, 2) database systems are organized hierarchically so that working data C8Mot be referenced by other application systems until they are released into the global database, and 3) integrity constraints written in EXPRESS are validated both in the local databases and the global database. By keeping the integrity of the product data, undesirable propagation of illegal data to other application system can be prevented. For efficient validation, the constraints are distributed into the local and the global schemata. Separate triggering mechanisms are devised using the dependency of constraints to three different data operations, i.e., insertion, deletion, and update.

• 음성과학
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• 제7권3호
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• pp.87-98
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• 2000

Timing in speech is determined by many factors. In this paper, we introduce and discuss some factors that have generally been regarded as important in speech timing. They include stress, syllable structure, consonant insertion or deletion, tempo, lengthening at clause, phrase and word boundaries, preconsonantal vowel shortening, and compensation between segments or within phonological units (e.g., word, foot), compression due to the increase of syllables in word or foot level, etc. and each of them may playa crucial role in the structuring of speech timing in a language. But some of these timing factors must interact with each other rather than be independent and the effects of each factor on speech timing will vary from language to language. On the other hand, there could well be many other factors unknown so far. Finding out and investigating new timing factors and reinterpreting the already-known timing factors should enhance our understanding of timing structures in a given language or languages.

• Journal of Electrical Engineering and information Science
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• 제1권1호
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• pp.1-9
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• 1996

A key issue in spoken language processing has become the integration of speech understanding and natural language processing(NLP). This paper presents a parallel computational model for the integration of speech and NLP. The model adopts a hierarchically-structured knowledge base and memory-based parsing techniques. Processing is carried out by passing multiple markers in parallel through the knowledge base. Speech-specific problems such as insertion, deletion, and substitution have been analyzed and their parallel solutions are provided. The complete system has been implemented on the Semantic Network Array Processor(SNAP) and is operational. Results show an 80% sentence recognition rate for the Air Traffic Control domain. Moreover, a 15-fold speed-up can be obtained over an identical sequential implementation with an increasing speed advantage as the size of the knowledge base grows.

• 아동학회지
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• 제28권4호
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• pp.73-95
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• 2007

Causal relationships of kindergarteners' phonological awareness and processing to their ability to read words was investigated with the participation of 289 4- to 6-year-old children attending three kindergartens in Busan. Results showed gradual growth in reading ability with age. Children performed best in reading words and poorest in reading low frequency letters. They showed continuous development in skills of syllable deletion, phoneme substitution, phoneme insertion, phonological memory and naming. Discontinuous development was found in counting syllables. Longer syllables were difficult to count, and middle syllables of 3 syllable words were hard to delete. Children had poor perception of final consonants of Consonant-Vowel-Consonant syllables. Children's phonological awareness and processing were latent variables strongly related to ability to read words written in Hangul.