• Journal of the Korean Regional Science Association
• /
• v.15 no.1
• /
• pp.45-61
• /
• 1999

A rapid growth of science parks worldwide since 1980s is caused by both the widespread perception that technological innovation is the essential element for the economic development and the notified cases of successful high technology cluster like Silicon Valley. Analyzed in terms of R & D employment and expenditure, new product launches, patent registration, qualifications of the founder, self-rated technological level and the like, the technological level of the science parks in the U.K. reveals very high. While nealy half of the firms on the science parks are represented to be formally linked with universities, the use of the library is referred most frequently among the types of the linkages. R & D links such as contract research, sponsored research, test and analysis were rarely mentioned. Summing up, science parks play an important role for the development of high-tech industries with superior technological characteristics. But in reatlity, there remains so much difference among the individual parks and their location. In addition the individual parks and their location. In addition, institutionalization of the technology transfer with univeristies that only when the science parks are based on the innovative environment they can be successful in the capability of the technological innovation.

• The Journal of the Convergence on Culture Technology
• /
• v.6 no.4
• /
• pp.15-20
• /
• 2020

A manufacturing industry has secured its competitiveness through cost reduction, research for new products, development of manufacturing technology traditionally. However, many manufacturers are being required of innovative efforts for business sustainability by emergence of new technology and industry owing to fast technology development and convergence among technologies and industries. Continuous growth can not be expected with the way of simple manufacturing and sales under the 4^th industrial revolution era. Separation of service from product is getting more vague in some specific area and a service provider is often offering its own product together. Innovation destroying manufacturing value chain with servitization can only create the new value. Basic concept of servitization, paradigm change and future prospect of manufacturing industries suffering from the 4^th industrial revolution will be analyzed in this paper. Also, the strategy, application and methodology for servitization required in the convergence period will be researched.

• Science of Emotion and Sensibility
• /
• v.7 no.2
• /
• pp.107-121
• /
• 2004

Although consumer needs for better products force manufactures to put emphasis on design, often development of a product has been done without the formal phase to consider human needs. In order to identify the implicit needs of customers and the areas of potential demand on a product, several analysis scheme such as QFD(quality function deployment) has been developed. For this, first of all, the methods for evaluating consumers satisfaction about their needs must be determined. However there were only few systematic methods on shoe design. In this paper we developed an innovative framework for human satisfaction evaluation of shoes. As a result, we uncovered 29 dominant human satisfaction dimensions for customer-oriented quality evaluation of a comfortable shoes. Here, 29 satisfaction dimensions were identified as the dimensions that represent the human sensitivity and psychological feeling on comfortable shoes. This study helped the designers and developers clarify the conceptual and abstract aspect of the design evaluation by proposing a more systematic and process-oriented method.

• Asia Pacific Journal of Business Review
• /
• v.2 no.1
• /
• pp.53-68
• /
• 2017

The objective of this research is to analyze the product innovation aspect in two comparable smartphones and partly illustrate perception and preference of Vietnamese consumers of two smartphone lines of Apple - iPhone 6 Plus and Samsung - Samsung Galaxy Note 4. The research tries to clarify which innovative features in two smartphones are more preferable to a group of consumer in Vietnam. The reason why the research studies iPhone 6 Plus and Samsung Galaxy Note 4 when iPhone 7 and Samsung Galaxy Note 7 have just released is that passing more than one year is enough time for consumers to totally experience both 2 smartphone lines to give the most precise and truthful evaluation for their preferences. Moreover, iPhone 6 Plus launch signed one of the most historical memorable landmark in the development process of iPhone products when it introduced larger-screen iPhone model for the first time. It is such an important change of iPhone which could open a new continuing successful era for Apple and iPhone. The first phase of this study involves analyzing strengths and weaknesses existed considering the opportunities and threats from the competitive market, then a competitive advantage analysis is implemented for each product. The second phase conducts a survey with Vietnamese participants from different backgrounds, by which a Mann-Whitney U test will be executed to check the significant difference in opinions in different respondent groups by age and by gender to several features of two smartphones. By conducting the survey, some interesting facts revealed with the winner seemingly falling into iPhone 6 Plus. However, it still reveals some significant difference among respondent groups by age and by gender to both iPhone 6 Plus and Samsung Galaxy Note 4 in several comparing features.

• Journal of Microbiology and Biotechnology
• /
• v.16 no.5
• /
• pp.651-660
• /
• 2006

Natural products are a rich source of biologically active small molecules and a fertile area for lead discovery of new drugs [10, 52]. For instance, 5% of the 1,031 new chemical entities approved as drugs by the US Food and Drug Administration (FDA) were natural products between 1981 and 2002, and another 23% were natural product-derived molecules [53]. These molecules have evolved through millions of years of natural selection to interact with biomolecules in the cells or organisms and offer unrivaled chemical and structural diversity [14, 37]. Nonetheless, a large percentage of nature remains unexplored, in particular, in the marine and microbial environments. Therefore, natural products are still major valuable sources of innovative therapeutic agents for human diseases. However, even when a natural product is found to exhibit biological activity, the cellular target and mode of action of the compound are mostly mysterious. This is also true of many natural products that are currently under clinical trials or have already been approved as clinical drugs [11]. The lack of information on a definitive cellular target for a biologically active natural product prevents the rational design and development of more potent therapeutics. Therefore, there is a great need for new techniques to expedite the rapid identification and validation of cellular targets for biologically active natural products. Chemical genomics is a new integrated research engine toward functional studies of genome and drug discovery [40, 69]. The identification and validation of cellular receptors of biologically active small molecules is one of the key goals of the discipline. This eventually facilitates subsequent rational drug design, and provides valuable information on the receptors in cellular processes. Indeed, several biologically crucial proteins have already been identified as targets for natural products using chemical genomics approach (Table 1). Herein, the representative case studies of chemical genomics using natural products derived from microbes, marine sources, and plants will be introduced.

• Journal of Biomedical Engineering Research
• /
• v.44 no.1
• /
• pp.41-52
• /
• 2023

With the international change in the medical device market owing to the development of innovative medical engineering and the use of various raw materials, a systematic and rational medical device classification system is needed to safely manage newly developed medical devices. This study aims to improve the domestic medical device classification system by proposing product establishment and segmentation. It is based on medical device products from the United States and Europe that are only available in foreign systems and are more subdivided than domestic products. This study analyzes and compares the domestic and foreign medical device classification systems by examining laws, guidelines, and analysis reports in Korea, the United States, and Europe. In accordance with product establishment and segmentation criteria, products subject to improvement are presented. This study contributes to safely managing medical devices that do not fit with the current classification system and to solving the confusion caused by the lack of international harmony in product classification systems.

• The Journal of Bigdata
• /
• v.9 no.1
• /
• pp.49-60
• /
• 2024

This study aims to provide insights for developing innovative products, based on reviews from females aged 30 to 70 who bought cosmetic cushions via TV home shopping. Analyzing 200,000 reviews with Selenium and NLP techniques, we found the main audience is in their 50s and 60s, prioritizing radiance, blemish and wrinkle coverage, and adherence. Notably, products with appealing designs were preferred, especially for gifting among relatives and friends. The proposed innovation is Korea's first AI-recommended cushion, utilizing NLP to match customer needs. Key ingredient recommendations include S.Acamella extract and AHA components, chosen for their perceived benefits and consumer preference. The research also highlights the importance of product aesthetics and gift potential, suggesting marketing strategies should emphasize these aspects to appeal to the target demographic. This approach aims to guide product development and marketing towards meeting consumer expectations in the cosmetic cushion industry, making products more personalized and gift-worthy.

• International Journal of Computer Science & Network Security
• /
• v.21 no.12
• /
• pp.309-315
• /
• 2021

The purpose of the article is to analyze the functioning of economic systems in the context of the development of their potential in a circular economy. It is determined that the functioning of economic systems to ensure their sustainability should meet modern challenges and provide for the formation of competitive institutional architecture, the introduction of structural and regulatory innovations, the transition to an innovative model of development. The specific principles of functioning of economic systems include openness, nonlinearity, multivectority, dynamism, emergence, uncertainty about the development of economic processes. It is substantiated that the linear nature of development and equilibrium are not dominant in the functioning of economic systems, and increasing the level of economic efficiency should go hand in hand with minimizing the activities of enterprises, which necessitates the use of circular economy. The main prerequisites for the transition to a circular economy are analyzed. It is determined that the basic concept of the circular economy involves the development of a system of production and consumption, which is based on processing, reuse, repair, product sharing, change of consumption patterns and new business models and systems. The main elements of the circular economy include: a closed cycle, the use of renewable energy sources, systems thinking. The correlation of the principles of sustainable development and the peculiarities of the application of the circular economy is analyzed. It is determined that the circular economy contrasts with the traditional linear economic model, which is based on the model of "take-do-consume-throw away". The advantages and disadvantages due to the use of the principles of circular economy are given. Based on the study, steps are identified to accelerate the transition from a linear economy to a circular economy.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.27 no.6
• /
• pp.839-846
• /
• 1994

Changing concepts in fishery science increasingly are recognizing depletion of traditional stocks, utilization of alternate(non-traditional) species, demand for high quality products, and a total resource utilization approach. Innovative practices are occurring in fisheries processing wherein solid and liquid discharges are no longer treated as 'waste,' but rather as valuable feedstocks for recovery of a variety of value-added ('value enhanced') by-products. Among these are protein hydrolysates, soluble proteins and amino acids, proteolytic enzymes, flavor and flavor extracts, pigments, and biopolymers such as chitosan. Properties and applications of this deacetylated derivative of chitin are noted. Crustacean processing by-products are discussed in terms of their serving as materials for generation of natural flavors and flavor extracts, and products such as fish sauces using contemporary enzymatic techniques. Various food and feed applications of fisheries processing by-products are illustrated with increased usage seen in formulated diets for an expanding aquaculture market. Examples are given of aquaculture becoming increasingly significant in global fisheries resource projections. Critical issues in the international seafood industry Include those of seafood quality, processing quality assurance (HACCP), and recognition of the nutritional and health-related properties of fisheries products. A variety of current seafood processing research is discussed, including that of alternate fish species for surimi manufacture and formulation of value-added seafood products from crawfish and blue crab processing operations. Increasing emphasis is being placed on international aspects of global fisheries and the role of aquaculture in such considerations. Coupled with the need for the aquatic food industry to develop innovative seafood products for the 21st century is that of total resource utilization. Contemporary approaches in seafood processing recognize the need to discard the traditional concept of processing 'waste' and adapt a more realistic, and economically sound, approach of usable by-products for food and feed application. For example, in a period of declining natural fishery resources it is no longer feasible to discard fish frames following fillet removal when a significant amount of residual valuable flesh is present that can be readily recovered and properly utilized in a variety of mince-based formulated seafood products.

• Journal of Microbiology and Biotechnology
• /
• v.29 no.5
• /
• pp.776-784
• /
• 2019

Polyhydroxybutyrate (PHB), the most well-known polyhydroxyalkanoate, is a bio-based, biodegradable polymer that has the potential to replace petroleum-based plastics. Lignocellulose hydrolysate, a non-edible resource, is a promising substrate for the sustainable, fermentative production of PHB. However, its application is limited by the generation of inhibitors during the pretreatment processes. In this study, we investigated the feasibility of PHB production in E. coli in the presence of inhibitors found in lignocellulose hydrolysates. Our results show that the introduction of PHB synthetic genes (bktB, phaB, and phaC from Ralstonia eutropha H16) improved cell growth in the presence of the inhibitors such as furfural, 4-hydroxybenzaldehyde, and vanillin, suggesting that PHB synthetic genes confer resistance to these inhibitors. In addition, increased PHB production was observed in the presence of furfural as opposed to the absence of furfural, suggesting that this compound could be used to stimulate PHB production. Our findings indicate that PHB production using lignocellulose hydrolysates in recombinant E. coli could be an innovative strategy for cost-effective PHB production, and PHB could be a good target product from lignocellulose hydrolysates, especially glucose.