• 품질경영학회지
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• 제27권4호
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• pp.67-94
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• 1999

TQM(total quality management) is accepted as the powerful and holistic management innovation tools in the worldwide corporations since "Malcom Baldrige National Quality Award" model is established by US government. But nowadays, TQM′s roles and positions for the competitiveness is challenged from other many management innovations tools. This paper identifies the TQM′s roles and positions as the sources of sustainable competitive advantages through the examples of Japanese manufacturing corporations which enjoy the strongest positions since 1980′s in world market.

• Asian Journal of Innovation and Policy
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• 제5권2호
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• pp.146-184
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• 2016

This paper analyzes the major comparisons and contrasts in entrepreneurship among technology-based university alumni over multiple decades from Tsinghua University in China and the Massachusetts Institute of Technology in the United States. In doing so, we ask two related research questions: (1) Who enters entrepreneurship and with what types of ideas and founding teams? (2) How do the innovation and other firm performance outcomes compare? We find that the sources of venture ideas and the composition of founding teams differ as well as the initial capital levels and revenues. This research provides a step toward a better understanding of high-tech entrepreneurship in developing vs. developed institutional environments. Furthermore, while MIT and Tsinghua University are unique in the programs they offer and in their historical cultures of entrepreneurship, both Tsinghua University and MIT provide benchmarks by which other institutions can gauge their alumni entrepreneurs and the types of ventures that they create.

• 기술혁신학회지
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• 제15권1호
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• pp.1-27
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• 2012

성공적인 개방형 혁신을 위해서는 조직 내부 기술 혹은 개발 전략과 함께 외부 자원을 동시에 고려하는 기술기획 도구가 필요하다. 본 연구는 개방형 혁신을 위한 조직 혹은 기업 내외부 자원 활용의 기획 수립과 수행을 위한 개방형 로드맵(open roadmap)을 제안한다. 개방형 로드맵은 내향적 그리고 외향적 개방형 혁신을 체계적으로 관리하고 계획하기 위해 사용된다. 또한 내향적, 외향적 혁신과 혁신 원천을 고려하여 여섯 가지 유형의 개방형 로드맵을 제시한다. 제안된 여섯 가지 유형의 개방형 로드맵은 P&G사의 혁신 성공 사례에 적용하여 개방형 로드맵의 유용성과 타당성에 대하여 검증하였다. 제안된 개방형 로드맵은 개방형 혁신을 지향하는 조직의 기술기획과 기술전략수립에 유용한 도구가 될 수 있을 것으로 기대된다.

• 기술혁신학회지
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• 제15권1호
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• pp.76-104
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• 2012

중소기업의 성장은 국가혁신체제(National Innovation System: NIS)에서 핵심적인 요소로서 그 중요성이 지속적으로 강조되고 있다. 최근, 작지만 강한 기업인 히든챔피언에 대한 관심이 증대되고, 이에 대한 성공모델을 제시함으로써 중소기업의 성공을 도모하려는 연구들이 확산되고 있다. 그러나 히든챔피언에 대한 정성적인 연구는 많은 반면, 정량적으로 분석한 연구는 미흡하기 때문에, 본 연구에서는 그와 유사한 세계선도 중소기업을 선정하여 기술혁신활동조사 자료를 통해 정량적인 방법으로 다른 유형의 중소기업과의 차이점을 분석하고, 혁신 성공요인을 도출하고자 한다. 이를 위해 첫째, 선행연구들을 통해 세계선도 중소기업의 혁신 성공요인 변수를 도출하고, 둘째, t검정, 카이스퀘어검정, 그리고 로지스틱회귀분석을 통해 정량적인 성공요인을 도출한다. 결과적으로, 중소기업은 정부기관과 박람회 같은 외부정보를 활용하여 시장추세와 비즈니스 기회를 파악하고, 정부에서는 중소기업 지원을 활발히 하여 세계선도 중소기업을 육성할 수 있을 것이다.

• Nuclear Engineering and Technology
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• 제54권6호
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• pp.2062-2066
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• 2022

Nuclear energy sources are indispensable in cost effectively achieving carbon neutral economy, where public opinion is critical to adoption as the consequences of nuclear accident can be catastrophic. In this context, discussion on spent nuclear fuel is a prerequisite to expanding nuclear energy, as it leads to the issue of radioactive waste disposal. Given the dearth of study on spent nuclear fuel public acceptance, we use text mining and big data analysis on the news article and public comments data on Naver news portal to identify the Korean public opinion on spent nuclear fuel. We identify that the Korean public is more interested in the nuclear energy policy than spent nuclear fuel itself and that the alternative energy sources affect the position towards spent nuclear fuel. We recommend relating spent nuclear fuel issue with nuclear energy policy and environmental issues of alternative energy sources to further promote spent nuclear fuel.

• 기술혁신학회지
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• 제21권2호
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• pp.767-787
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• 2018

본 연구는 기술혁신의 일자리 창출효과에 관해 산업조직론적인 관점에서 내/외부 기술소스가 고용에 미친 영향을 파악하고자 한다. 그간 과학기술 사업화정책은 공공부문이 생산한 기술을 기업이 흡습하여 기술력이 향상되면 부가가치가 창출되어 결과적으로 고용으로 이어진다는 가정에 기초하고 있으나, 실증적인 검증과 논의가 활발히 이루어지지는 못했다. 이에, 연구개발 활동을 수행하는 기업들의 재무데이터를 바탕으로 공공기술의 이전여부에 따라 기업의 고용지표를 비교하고 인과관계에 관해 분석한다. 성향점수기법을 활용하여 외부기술을 도입한 그룹과 자체 연구개발을 추진한 기업을 비교한 결과, 연구개발 전담인력과 기업 전체 고용인원 면에서 외부기술 도입그룹이 우세한 것으로 나타났다. 두 번째 분석파트에서 매개효과 모형을 이용해 연구개발 투자가 고용효과로 전환되는 인과적 영향을 파악한 결과, 외부기술 도입그룹의 전환효율성이 낮은 것으로 나타났다. 이를 종합해보면, 외부로부터 기술을 도입한 기업들은 기술을 내재화하는 과정, 후속개발 등에 추가적인 자원을 투입하는 것으로 파악된다. 고용효과 측면에서 볼 때, 이 결과는 기업이 외부로부터 기술을 도입하면 자체적인 투입요인(연구인력, 총 고용)을 줄일 수 있다는 선행연구와 달리, 분석대상 기업들은 둘 사이의 관계를 보완적으로 인식한다는 점을 시사한다.

• IMMUNE NETWORK
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• 제21권6호
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• pp.39.1-39.18
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• 2021

The high virulent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that emerged in China at the end of 2019 has generated novel coronavirus disease, coronavirus disease 2019 (COVID-19), causing a pandemic worldwide. Every country has made great efforts to struggle against SARS-CoV-2 infection, including massive vaccination, immunological patients' surveillance, and the utilization of convalescence plasma for COVID-19 therapy. These efforts are associated with the attempts to increase the titers of SARS-CoV-2 neutralizing Abs (nAbs) generated either after infection or vaccination that represent the body's immune status. As there is no standard therapy for COVID-19 yet, virus eradication will mainly depend on these nAbs contents in the body. Therefore, serological nAbs neutralization assays become a requirement for researchers and clinicians to measure nAbs titers. Different platforms have been developed to evaluate nAbs titers utilizing various epitopes sources, including neutralization assays based on the live virus, pseudovirus, and neutralization assays utilizing recombinant SARS-CoV-2 S glycoprotein receptor binding site, receptor-binding domain. As a standard neutralization assay, the plaque reduction neutralization test (PRNT) requires isolation and propagation of live pathogenic SARS-CoV-2 virus conducted in a BSL-3 containment. Hence, other surrogate neutralization assays relevant to the PRNT play important alternatives that offer better safety besides facilitating high throughput analyses. This review discusses the current neutralization assay platforms used to evaluate nAbs, their techniques, advantages, and limitations.

• 지식경영연구
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• 제18권4호
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• pp.181-211
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• 2017

Despite a growing literature focusing on technological development as a key driving force behind the economic performance of a firm or a nation's industy, we still fall short of a comprehensive understanding of how each of the elements required of technological developent and innovation fits togther and leads to economic progress and industry change. This paper seeks to fill this gap by bringing together some of key insights from the theory and research on the coevolutionary process of technology, organizations, and industry, and on the role of institutions in this process. By combining a diverse array of research streams, we provide a broad suvey of foundational work on the following two questions: (1) how the creation and diffusion of innovation occurs and gives rise to structural reconfigurations of the industry, (2) how organisations and technology coevolve, and (3) what is the role of institutions in this coevolutionary process? Based on this literature survey, we also offer a synthesis that can serve as a ground that allows a more nuanced understanding of the sources, dynamics and impacts of technological development and innovation, and interrelationships among technology, organizations and industry change.

• The Journal of Asian Finance, Economics and Business
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• 제9권8호
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• pp.157-167
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• 2022

The global laundry detergents market in 2021 was valued at nearly $121 billion, with consumers being reported as heightening their search for hygienic products capable of fighting viruses. Therefore, the researchers undertook a study to determine how product innovation (PI), product quality (PQ), and product attitude (PA) effects Thai consumers' satisfaction (CS) with their purchase of laundry detergent and fabric softener. After the questionnaire's validity and reliability confirmation, the authors used multi-stage random sampling by region and province in January and February 2022 to collect 520 questionnaires. LISREL 9.10 was used in the CFA and SEM analysis of the six hypotheses, which were determined to be supported. The results showed that all three causal variables positively influenced CS, with a total effect (TE) R² value = 87%. Also, latent variable total effect (TE) values showed that PI was strongest (0.93), then PQ (0.56), and finally, PA (0.54). Therefore, consumer satisfaction is essential in a firm's ongoing development and sustainability in a highly competitive, globalized world. Organizations must develop competitive strategies that adjust to consumer needs. Management must monitor online and social media sources where product reviews are given and adjust their strategies accordingly.

• Journal of Veterinary Science
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• 제22권6호
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• pp.74.1-74.13
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• 2021

Tissue engineering has been extensively investigated and proffered to be a potential platform for novel tissue regeneration. The utilization of mesenchymal stem cells (MSCs) from various sources has been widely explored and compared. In this regard, MSCs derived from bone marrow have been proposed and described as a promising cell resource due to their high yield of isolated cells with colony-forming potential, self-renewal capacity, MSC surface marker expression, and multi-lineage differentiation capacities in vitro. However, there is evidence for bone marrow MSCs (BM-MSCs) both in vitro and in vivo from different species presenting identical and distinct potential stemness characteristics. In this review, the fundamental knowledge of the growth kinetics and stemness properties of BM-MSCs in different animal species and humans are compared and summarized. Finally, to provide a full perspective, this review will procure results of current information studies focusing on the use of BM-MSCs in clinical practice.