• Journal of the Korean Society for Railway
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• v.6 no.1
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• pp.10-14
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• 2003

Since most of main noise sources of the railroad vehicle are transmitted to the passenger's ear through the vibration of the panel, the sound insulation performance of the panels should be high enough to protect the passenger's ear from the noisy environment. Specifically, the composite materials which are generally used for reducing the weight of the vehicle compartment have the low insulation performance, thus noise control actions should be taken appropriately by considering the insulation performance of the panels. In this study, the insulation performances of the inner/outer panels of the compartment are evaluated. In addition, the contribution of the insulation performance of aluminum door is estimated and compared to those of composite panels. The results can furnish an in-depth understanding of the insulation characteristics of the panel of railroad vehicle.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.3
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• pp.158-164
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• 2005

Meniere's disease is not a life-threatening but lift-altering inner ear disease characterized by episodic vertigo, fluctuating hearing loss, tinnitus and ear fullness. The etiology and pathophysiology symptoms is still disputed. Thereby the treatment of Meniere's disease is empirical. As yet no treatment has prospectively modified the clinical course of condition and thereby prevented the progressive hearing loss. We experienced two cases of Meniere's disease treated with oriental medical treatment, acupuncture and herbal medication. 15 year-old and 23 year old male patients had diagnosed Meniere's disease by western medical doctor. After treatment their vertigo is decreased and the level of hearing loss was rise up. Therefore, oriental medical treatments could be safe and effective methods.

• Animal Systematics, Evolution and Diversity
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• v.40 no.3
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• pp.221-253
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• 2024

Eight new species of the genus Acanthomolgus are described as external associates of octocorallian corals from Korea. As diagnostic features of these new species, A. taenichaetatus n. sp. has ribbon-like distal caudal setae; A. jei n. sp. and A. crassae n. sp. have no inner proximal expansion on the exopodal segment of female leg 5, and the former species has only three setae on the maxillule (vs. four setae in other seven species). Acanthomolgus notialis n. sp. is similar to A. oporinus n. sp. in having a rounded inner proximal expansion on the exopodal segment of female leg 5, but the latter species is distinguished from the former by having longer caudal rami which are about 1.5 times longer than wide, by having a longer inner seta of the maxilla which is three quarters as long as distal lash, and by having unequal setae on the basis of maxilliped. Acanthomolgus dokdoicus n. sp., A. rugosus n. sp. and A. triplus n. sp. appear to be similar to one another in having an ear-like inner proximal expansion on the exopodal segment of female leg 5, but the genital double-somite of the female is distinctly longer than wide in A. rugosus n. sp. (wider than long in other two species), and the third endopodal segment of the antenna is distinctly shorter than the first endopodal segment in A. triplus n. sp. (vice versa in other two species). This is the first record on the genus Acanthomolgus in the temperate West Pacific.

• BMB Reports
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• v.53 no.3
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• pp.160-165
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• 2020

The root meristem of Arabidopsis thaliana is protected by the root cap, the size of which is tightly regulated by the balance between the formative cell divisions and the dispersal of the outermost cells. We isolated an enhancer-tagged dominant mutant displaying the short and twisted root by the overexpression of ZINC-FINGER OF ARABIDOPSIS THALIANA1 (ZAT1) encoding an EAR motif-containing zinc-finger protein. The growth inhibition by ZAT1 was shared by ZAT4 and ZAT9, the ZAT1 homologues. The ZAT1 promoter was specifically active in the outermost cells of the root cap, in which ZAT1-GFP was localized when expressed by the ZAT1 promoter. The outermost cell-specific expression pattern of ZAT1 was not altered in the sombrero (smb) or smb bearskin1 (brn1) brn2 accumulating additional root-cap layers. In contrast, ZAT4-GFP and ZAT9-GFP fusion proteins were distributed to the inner root-cap cells in addition to the outermost cells where ZAT4 and ZAT9 promoters were active. Overexpression of ZAT1 induced the ectopic expression of PUTATIVE ASPARTIC PROTEASE3 involved in the programmed cell death. The EAR motif was essential for the growth inhibition by ZAT1. These results suggest that the three related ZATs might regulate the maturation of the outermost cells of the root cap.

• Journal of Sensor Science and Technology
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• v.11 no.3
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• pp.171-182
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• 2002

The differential electromagnetic transducer for IME(implantable middle ear) system, which have two small permanent magnets glued with the same pole facing each other in the coil, has high vibration efficiency and does not influenced by external magnetic field. In this paper, using finite element method, highly efficient structure of the transducer was proposed and vibration force of the transducer was calculated by electromagnetic theory. And the necessary vibration force of transducer to transmit the sound signal to inner ear when the transducer is attached at stapes was calculated and the design parameters of the transducer were investigated. Using the parameters, the differential electromagnetic transducer was manufactured in small size to implant in confined human middle ear. And it was examined by unloaded and loaded vibration experiment using temporal bone sampled from cadaver.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.24 no.1
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• pp.113-126
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• 1998

Inner nutshell of Castanea crenata has been used as an anti-aging and anti-wrinkle agent from the ancient time in east Asia. In order to develop new anti-aging and anti-wrinkle, ethanolic extract of inner nutshell of Castanea crenata was prepared and various biological activities were evaluated. Cor-285 possessed potent tree radical scavenging activity in vitro compared to gallic acid. Cor-285 showed the preventive effect against UV-induced cytotoxicity of fibroblast at concentration of 25-250mg/ml. When Cor-285 was evaluated for its anti-allergic activity, it effectively inhibited histamine release from mast cells induced by compound 48/80. The inhibitory activity was stronger than that of glycyrrhizinate. Cor-285 also showed on vivo inhibition against delayed hypersensitivity as well as croton-oil induced ear edema in mice when topically applied. These results strongly suggest that Cor-285 may reduce immunoregulatory/inflammatory skin trouble. From the attempts to isolate the scavenger, were isolated. In a clinical trial of twenty healthy volunteers with aged skin, 6 weeks application of Cor-285 decreased wrinkle about 26% and increased moisturizing 20% on the skin. All of these results indicate that Cor-285 may be an effective anti-aging and anti-wrinkle agent.

• Journal of Biomedical Engineering Research
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• v.20 no.4
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• pp.495-502
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• 1999

We propose efficient speech signal processing algorithms and a system for cochlear implant in this paper. The outer and the middle car which perform amplifying, lowpass filtering and AGC, are modeled by an analog system, and the inner ear acting as a time-delayed multi filter and the transducer is implemented by the DSP circuit which enables real-time processing. Especially, the basilar membrane characteristic of the inner ear is modeled by a nonlinear filter bank, and then tonotopy and periodicity of the auditory system is satisfied by using a pitch-synchronous multi-spectra(PSMS) method. Moreover, most of the speech processing is performed by S/W so the system can be easily modified. And as our program is written in C-language, it can be easily transplanted to the system using other processors.

• Journal of Acupuncture Research
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• v.21 no.6
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• pp.269-279
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• 2004

Meniere's disease is not a life-threatening but life-altering inner ear process characterized by episodic vertigo, fluctuating hearing loss, tinnitus, and ear fullness. The etiology and pathophysiology of the symptoms is still disputed. Thereby the treatment of Meniere's disease is empirical. As yet, no treatment has prospectively modified the clinical course of the condition and thereby prevented the progressive hearing loss. We experienced two cases of Meniere's disease treated with herbal medication and acupuncture. 62 year-old male and 64 year-old female patients had definite Meniere's disease. Banhabaeckchulchunma-tang was administered in both cases. After treatment Vertigo attacks were completely controlled in both, whereas Hearing level remained unchanged. Tinnitus was improved in one patient and unchanged in the other. Therefore, Banhabaeckchulchunma-tang and acupuncture could be a safe and simple therapeutic modality that is effective in controlling the vertigo ; however further studies must be done on hearing preservation and tinnitus.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.11 no.1
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• pp.180-196
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• 1998

A Literatur Review of Physical and Breathing Exercises for Ear Health, the results were as follows. 1. The most common using way is rubbing your ears and auricle with warm palms. 2. To stimulate inner acoustic meatus, obstruct external acoustic meatus for a short time by the palm or fingers and then to stimulate it by the sudden opening. 3. This method is a common way to press aurical or orifice of external acoustic meatus for example, TE21(耳門), TE20(角孫), GB2(聽會), TE19(노息), TE18(계脈), GB11(竅陰), TE17(예風) etc. 4. The best time to pratice is early in the morning or before go to bed, but a litter difference by the writer's opinion, so there is not consistency. 5. Since tinnitus and hardness of hearing is related to the who1e body, it is known that you can relax your whole body by pressing the acupuncture points located in the head of occipital region or by stretching the upper half of the body. 6. There is method that obstruct your ears with palms and 3rd finger on your occipital region and splash by the 2th fingers.(sound the celestial drum)

• Genomics & Informatics
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• v.20 no.1
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• pp.5.1-5.10
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• 2022

Non-syndromic hearing loss (NSHL) is a common hereditary disorder. Both clinical and genetic heterogeneity has created many obstacles to understanding the causes of NSHL. The present study has attempted to ravel the genetic aetiology in NSHL progression and to screen out potential target genes using computational approaches. The reported NSHL target genes (2009-2020) have been studied by analyzing different biochemical and signaling pathways, interpretation of their functional association network, and discovery of important regulatory interactions with three previously established miRNAs in the human inner ear as well as in NSHL such as miR-183, miR-182, and miR-96. This study has identified SMAD4 and SNAI2 as the most putative target genes of NSHL. But pathogenic and deleterious non-synonymous single nucleotide polymorphisms discovered within SMAD4 is anticipated to have an impact on NSHL progression. Additionally, the identified deleterious variants in the functional domains of SMAD4 added a supportive clue for further study. Thus, the identified deleterious variant i.e., rs377767367 (G491V) in SMAD4 needs further clinical validation. The present outcomes would provide insights into the genetics of NSHL progression.