• Journal of Nutrition and Health
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• v.28 no.4
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• pp.298-308
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• 1995

To investigate the effect of estrogen and dietary protein level on Ca metabolism, female rats were undergone ovariectomy or sham-operation. Ovariectomized rate were divided into either estrogen-or vehicle-treated groups. Each treatment group was again divided into 40%-casein(H) or 10%-casein(L) diet groups. All experimental diets contained 0.2% Ca, 0.4% P and fed to rats for 8 weeks. Apparant Ca absorption and Ca balance were not affected by dietary protein level and ovariectomy, however they were increased by estrogen injection and this effect was even higher in low protein groups. Urinary Ca excretion were higher in high protein groups. GFR was not affected by dietary protein level, ovariectomy, or by estrogen injection. Urinary protein excretion was higher in high protein groups, which implies that the kidney funtion was deteriorated by high protein diet, and this may account partly for the higher urinary Ca in high protein groups. Ovariectomy or estrogen treatment had no effect on urinary protein excretion. Urinary hydroxyproline was higher in ovariectomized rats and increased in high protein grous. Elevated value of ovarictomized rats was lowered by estrogen injection, especially in low protein group. Alkaline phosphatase tended to increase in ovariectomized groups and lowered with estrogen treatment, but this difference was not statistically significant. Serum PTH was not affected by ovariectomy and dietary protein level. Therefore the increased hydroxproline excretion does not seem to be attributed to PTH. Dietary protein level, ovariectomy and estrogen treatment did not affect the weights and components of femur, scapular, and 4th vertebra. Ash/wt ratio of femur was, however, lower in ovariectomized rats and increased with estrogen treatment. Therefore, among the bones studied, femur seemed to be the most vulnerable. The results of this study shows that estrogen treatment may alleviate or reduce bone loss in postmenopausal women somewhat, especially for those people with low protein diet.

• Korean Journal of Head & Neck Oncology
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• v.19 no.1
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• pp.21-24
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• 2003

Objectives: In this report, we confirmed the distributed pattern of ALA and ALA-methylester in normal and tumor-bearing region. Materials and Methods: ALA and ALA-methylester were administered to nude mouse by intratumoral, subcutaneous and intravenous injection. After injection, the fluorescence in normal and tumor region was measured by LESA (laser electronic spectrum analyzer). Results: The tumor-specificity of ALA and ALA-methylester was shown in the case of intratumoral injection. In all case, the fluorescence caused by ALA and ALA-methylester was maximally increased in 2 hours after injection. Then while the fluorescence level was rapidly decreased to control level in normal region, it was still remained in tumor region. Conclusion: According to this result, The intratumoral injection was more efficient administration method for PDT/PDD than subcutaneous and intravenous injection.

• Korean Journal of Veterinary Service
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• v.41 no.4
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• pp.251-255
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• 2018

Bordetella bronchiseptica and Pasteurella multocida are two main pathogens responsible for atrophic rhinitis (AR), which causes considerable economic losses in swine industry worldwide. Commercial vaccine has been widely used to prevent the damage from AR in Korea. Adverse effects of vaccination at the injection site have been reported, which results in the numerous complaint from farms. However, data on about local reaction at the injection site remains limited. In this study, we compared the local adverse effects of three commercial vaccines following intramuscular injection. The results showed that no gross lesion was founded at the injection sites of all three vaccines. In histopathologic examination, a various level of lesions was identified. Especially, the local reaction of vaccine including saponin as an adjuvant showed the lowest level of histopathological lesions, when compared to those of oil-based and vitamin E-based vaccines. Therefore, this study would provide the information about the extent of local reaction at the injection site and help the farmer to select AR vaccine in order to avoid adverse reaction due to vaccination.

• The Journal of Engineering Geology
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• v.30 no.3
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• pp.269-278
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• 2020

In this study, the effects of groundwater artificial recharge through vertical wells in the upper small basin are preliminarily evaluated by using field injection test and a 3-D numerical model. The injection rate per well in a model is set to 20, 37.5, 60, and 75 ㎥/day based on the results of field injection test, groundwater levels, and hydraulic conductivities estimated from particle size analysis, and a numerical model using MODFLOW is conducted for 28 cases, which have diverse injection intervals, in order to estimated the changes of groundwater level and water balance after injection. Groundwater level after injection does not show a linear relationship with the injection rate per well, and the cumulative effect of artificial recharge decreases and the timing of maximum water level rise is shortened as the injection interval becomes longer. In four cases of continuous injection with total injection rate of 1,200 ㎥, it is revealed that the recharge effect is analyzed as 36.5~65.3% of the original injection rate. However, it will be more effective if the artificial recharge system combined with underground barrier is introduced for the longer pumping during a long and severe drought. Additionally, it will be possible to build a stable artificial recharge system by an establishment of efficient scenario from recharge to pumping as well as an optimization of recharge facilities.

• Design & Manufacturing
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• v.14 no.3
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• pp.8-16
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• 2020

In this study, the vibration signal of the mold was measured and analyzed to monitoring the process time and characteristics during injection molding. A 5 inch light guide plate mold was used to injection molding and the vibration signal was measured by MPU6050 acceleration sensor module attached the surface of fixed mold base. Conditions except for injection speed and packing pressure were set to the same value and the change of the vibration signal of the mold according to injection speed and packing pressure was analyzed. As a result, the vibration signal had a large change at three points: "Injection start", "V/P switchover", and "Packing end". The time difference between "injection start" and "V/P switchover" means the injection time in the injection molding process, and the time difference between "V/P switchover" and "Packing end" means the packing time. When the injection time and packing time obtained from the vibration signal of the mold are compared with the time recorded in the injection molding machine, the error of the injection time was 2.19±0.69% and the error of the packing time was 1.39±0.83%, which was the same level as the actual value. Additionally, the amplitude at the time of "injection start" increased as the injection speed increased. In "V/P switchover", the amplitude tended to be proportional to the pressure difference between the maximum injection pressure and the packing pressure and the amplitude at the "packing end" tended to the pressure difference between the packing pressure and the back pressure. Therefore, based on the result of this study, the injection time and packing time of each cycle can be monitored by measuring the vibration signal of the mold. Also, it was confirmed that the level and trend of process variables such as the injection speed, maximum injection pressure, and packing pressure can be evaluated as the change of the mold vibration during injection molding.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2007.05a
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• pp.217-220
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• 2007

The quality of product depends on a lots of injection molding conditions at each operation stage and mainly was effected by pressure and temperature. The objective of this study was to investigate the relationship between the product quality and the distribution of pressure in a cavity with operation condition change. Specimen having some ribs was designed and the mold was prepared and temperature and pressure sensors were installed in the mold. PP was used and pressure distribution was measured with operation condition change. The relationship between the sink mark and the pressure in a cavity was investigated by measurement of the level of sink mark. The level of sink mark was decreased at the cross of plane and rib by increasing of pressure in a cavity, so the pressure should be controlled properly in order to get the required quality.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2007.05a
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• pp.195-198
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• 2007

The present work focuses on the prediction of birefringence in injection-molded plastic part and its improvement by rapid mold heating. To calculate birefringence, flow-induced residual stress is computed through a fully three-dimensional injection molding analysis. Then the stress-optical law is applied from which the order of birefringence can be evaluated and visualized. The birefringence patterns are predicted for a rectangular plate with a variation of mold temperatures, which shows that the amount of molecular orientation and birefringence level decreases with an increase of mold temperature. The effect of mold temperature on the order of birefringence is also studied for a thin-walled rectangular strip, and compared with experimental measurements. Both predicted and experimental patterns of birefringence are in agreements on the observation that the birefringence level diminishes significantly when the mold temperature is raised to above the glass transition temperature.

• Journal of Chest Surgery
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• v.26 no.7
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• pp.538-542
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• 1993

An approach to the treatment of post-operative pain by the injection of bupivacaine into the pleural space through an intrapleural cathter has been studied. Among 24 thoracotomy patients, bupivacaine was injected only to experimental group[ 12 patients ] when the patient was able to head up for oneself during recovery from anesthesia. The pain and ROM[ range of motion ] scores, respiration rate, PaCO2 level of both experimental and control group were measured at the time of head-up and 30 and 120 minutes thereafter.The scores of pain and ROM of experimental group were significantly[ P value < 0.05 ] decreased in 30 minutes and 120 minutes after bupivacaine injection compared with those of control group but respiration rate and PaCO2 level were not changed significantly. With this result, we can suggest that intrapleural injection of bupivacaine is useful for pain relief following thoracotomy.

• Transactions of Materials Processing
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• v.16 no.4 s.94
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• pp.229-233
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• 2007

The present work focuses on the prediction of birefringence in injection-molded part and its improvement by rapid mold heating. To calculate birefringence, flow-induced residual stress is computed through a fully three-dimensional injection molding analysis. Then the stress-optical law is applied from which the order of birefringence can be evaluated and visualized. The birefringence patterns are predicted for a rectangular plate with a variation of mold temperature, which shows that the amount of molecular orientation and birefringence level decreases with an increase of mold temperature. The effect of mold temperature on the order of birefringence is also studied for a thin-walled rectangular strip, and the relevant results are compared with experimental measurements. Both predicted and experimental patterns of birefringence are in agreements on the observation that the birefringence level diminishes significantly when the mold temperature is raised over the glass transition temperature.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.1
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• pp.229-237
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• 1996

For the practical use of a fuel injection system using solenoid, some mechanical and electrical problems should be explicitly analyzed. In our study, we have investigated these problems experimentally and have improved such that a solenoid driving circuit is liable to establish a fast reponse and a precise control of injection quantity. This proposed fuel injecton system is capable to control equivalence ratio from low level to high level. Therefore, we expect that this proposed system should be applicable to an actual engine.