• Title/Summary/Keyword: Initial diameter

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Application of Electrospun Silk Fibroin Nanofibers as an Immobilization Support of Enzyme

  • Lee Ki Hoon;Ki Chang Seok;Baek Doo Hyun;Kang Gyung Don;Ihm Dae-Woo;Park Young Hwan
    • Fibers and Polymers
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    • v.6 no.3
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    • pp.181-185
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    • 2005
  • Silk fibroin (SF) nanofibers were prepared by electrospinning and their application as an enzyme immobilization support was attempted. By varying the concentration of SF dope solution the diameter of SF nanofiber was controlled. The SF nanofiber web had high capacity of enzyme loading, which reached to $5.6\;wt\%$. The activity of immobilized a-chymotrypsin (CT) on SF nanofiber was 8 times higher than that on silk fiber and it increased as the fiber diameter decreased. Sample SF8 (ca. 205 nm fiber diameter) has excellent stability at $25^{\circ}C$ by retaining more than $90\%$ of initial activity after 24 hours, while sample SF11 (ca. 320 nm fiber diameter) shows higher stability in ethanol, retaining more than $45\%$ of initial activity. The formation of multipoint attachment between enzyme and support might increase the stability of enzyme. From these results, it is expected that the electrospun SF nanofibers can be used as an excellent support for enzyme immobilization.

Decolorization of Rhodamine B Using Quartz Tube Photocatalytic Reactor (석영관 광촉매 반응기를 이용한 Rhodamine B의 색도 제거)

  • Park Young Seek
    • Journal of Environmental Health Sciences
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    • v.30 no.5 s.81
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    • pp.358-365
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    • 2004
  • The photocatalytic oxidation of Rhodamine B(RhB) was studied using photocatalytic reactor filled with module of quartz tube. Module of quartz tube consisted of small quartz tube (inner diameter, 1.5 mm; outer diameter, 3 mm) bundle coated with powder $TiO_2$ and uncoated large quartz tube (inner diameter, 20 mm; outer diameter, 22 mm). Two 30 W germicidal lamp was used as the light source and the reactor volume was 0.5 l. The effects of parameters such as the coating materials and numbers, initial concentration, $H_{2}O_2$ dose and metal deposition (Ag, Pt and Fe) and simultaneous application of $H_{2}O_2$ and metal deposition. The results showed that the initial reaction constant of quartz module coated with powder $TiO_2$ was higher 1.4 time than that of the $TiO_2$ sol and optimum coating number is twice. In order to increase reaction rate, simultaneous application of photocatalytic and photo-fenton reaction using Fe coating and dose $H_{2}O_2$ dose increased reaction rate largely.

Development of Mandrel Forging Process for Large Conical Aluminum Shell (대형 원뿔형 알루미늄 실린더의 멘드렐 단조 공정 개발)

  • Nam, J.W.;Cho, J.R.;Lee, K.H.;Lee, I.H.
    • Transactions of Materials Processing
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    • v.27 no.5
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    • pp.276-280
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    • 2018
  • This paper has developed a forging process for conical shells for making aluminum cylindrical large shells. An incremental forging process was applied to reduce forging loads and die cost. The preform is designed based on the crosssectional area of the final forged shape. Inner diameter of the preform for mandrel forging is constant, and outer diameter is conical so that it matches the cross-sectional area of the product. However, simulation confirmed that the larger diameter is smaller than predicted and the length is larger than predicted because in the initial stage of forging, the large diameter portion first comes into contact with the anvil at the initial stage of forging and stretches in longitudinal direction. So, it has developed a rule to design the preform considering 3-D deformation instead of plane strain deformation at the beginning stage of mandrel forging. The developed mandrel forging process can be applied to more similar products and economic benefits may be obtained.

Megaoesophagus Seconday to Myasthenia Gravis in Three Dogs (중증근무력증에 의한 개의 거대식도증 3례)

  • Lee, Hee-Chun;Jeon, Joon-Hyeok;Cho, Kyu-Woan;Kang, Byeong-Teck;Jung, Dong-In
    • Journal of Veterinary Clinics
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    • v.29 no.1
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    • pp.107-111
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    • 2012
  • Three dogs (An 8 years-old intact female Poodle, a 7 years-old intact male Schunauzer, and an 8 yearsold Golden Retriever) were presented due to acute vomiting, dyspnea, and generalized weakness. Megaesophagus was confirmed through radiographic examination in all 3 dogs. Relative oesophageal diameter (ROD) was measured and results of ROD measurements showed the possibility of megaesophagus secondary to myasthenia gravis in three dogs. Thus we performed anticholinesterase test as screening test for myasthenia gravis. In all three dogs, esophageal diameter was reduced after neostigmine methylsulfate administration. For definite diagnosis of acquired myasthenia gravis, serum acetylcholine receptor antibody titer was measured, but definite diagnosis was confirmed only in one case. However, based on history, radiographic findings, anticholinesterase test, ROD measurement, other two cases were still suspected as megaesophagus secondary to myasthenia gravis. Treatment with pyridostigmine bromide was initiated in all dogs, and improvement of esophageal diameter was shown in all dogs. One dog was successfully managed for 15 months after initial treatment and, is still alive, but other two dogs were died shortly after initial treatment, because of severe aspiration pneumonia.

Parametric study of a new tuned mass damper with pre-strained SMA helical springs for vibration reduction

  • Hongwang Lv;Bin Huang
    • Smart Structures and Systems
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    • v.31 no.1
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    • pp.89-100
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    • 2023
  • This paper conducts a parametric study of a new tuned mass damper with pre-strained superelastic SMA helical springs (SMAS-TMD) on the vibration reduction effect. First, a force-displacement relation model of superelastic SMA helical spring is presented based on the multilinear constitutive model of SMA material, and the tension tests of the six SMA springs fabricated are implemented to validate the mechanical model. Then, a dynamic model of a single floor steel frame with the SMAS-TMD damper is set up to simulate the seismic responses of the frame, which are testified by the shaking table tests. The wire diameter, initial coil diameter, number of coils and pre-strain length of SMA springs are extracted to investigate their influences on the seismic response reduction of the frame. The numerical and experimental results show that, under different earthquakes, when the wire diameter, initial coil diameter and number of coils are set to the appropriate values so that the initial elastic stiffness of the SMA spring is between 0.37 and 0.58 times of classic TMD stiffness, the maximum reduction ratios of the proposed damper can reach 40% as the mass ratio is 2.34%. Meanwhile, when the pre-strain length of SMA spring is in a suitable range, the SMAS-TMD damper can also achieve very good vibration reduction performance. The vibration reduction performance of the SMAS-TMD damper is generally equal to or better than that of the classic optimal TMD, and the proposed damper effectively suppresses the detuning phenomena that often occurs in the classic TMD.

Growth Pattern and Prognostic Factors of Untreated Nonfunctioning Pituitary Adenomas

  • Hwang, Kihwan;Kwon, Taehun;Park, Jay;Joo, Jin-Deok;Han, Jung Ho;Oh, Chang Wan;Kim, Chae-Yong
    • Journal of Korean Neurosurgical Society
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    • v.62 no.2
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    • pp.256-262
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    • 2019
  • Objective : Pituitary adenomas (PAs) are often detected as incidental findings. However, the natural history remains unclear. The objective of this study was to evaluate the natural history and growth pattern of untreated PAs. Methods : Between 2003 and 2014, 59 PAs were managed with clinico-radiological follow up for longer than 12 months without any kind of therapeutic intervention. Tumor volumes were calculated at initial and last follow-up visit, and tumor growth during the observation period was determined. Data were analyzed according to clinical and imaging characteristics. Results : The mean initial and last tumor volume and diameter were $1.83{\pm}2.97mL$ and $13.77{\pm}6.45mm$, $2.85{\pm}4.47mL$ and $15.75{\pm}8.08mm$, respectively. The mean annual tumor growth rate was $0.33{\pm}0.68mL/year$ during a mean observation period of $46.8{\pm}32.1months$. Sixteen (27%) PAs showed tumor growth. The initial tumor size (HR, 1.140; 95% confidence interval, 1.003-1.295; p=0.045) was the independent predictive factor that determined the tumor growth. Six patients (11%) of 56 conservatively managed non-symptomatic PAs underwent resection for aggravating visual symptoms with mean interval of 34.5 months from diagnosis. By Cox regression analysis, PAs of last longest diameter over 21.75 mm were a significant prognostic factor for eventual treatment. Conclusion : The initial tumor size of PAs was independently associated with the tumor growth. Six patients (11%) of conservatively managed PAs were likely to be treated eventually. PAs of last follow-up longest diameter over 21.75 mm were a significant prognostic factor for treatment. Further studies with a large series are required to determine treatment strategy.

A Study on the Forging of Spur Gears with Variation of Inner Diameter in Hollow Billets (중공소재의 재경 변화에 따른 스퍼어기어 단조에 관한 연구)

  • 조해용;최재찬;최종웅;민규식
    • Transactions of Materials Processing
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    • v.4 no.3
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    • pp.257-266
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    • 1995
  • A simulation method based on upper bound method is developed in order to characterize forging characters in forging of spur gears. In this paper, utilizing a kinematically admissible velocity field and applying it to investigate the effect of inner diameter of holow billet. In the analysis, to predict the variation of inner diameter of hollw billet, neutral surface has been introduced. The neutral surface of each step is assumed as a circle and determined in order to have minimum forging energy by golden section method. By this method, the variation of inner diameter of billet during spur gear forging is successfully predicted. As a result, the selection of inner diameter of initial billet is very important to reduce the forging load.

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Effects of geometrical initial imperfection in proportioning member sections of single layer reticulated dome (단층 래티스 돔의 단면산정에 있어서의 형상초기불완전의 영향)

  • Kim, Jong-Min;HwangBo, Seok;Han, Sang-Eul;Kwun, Teak-Jin
    • 한국공간정보시스템학회:학술대회논문집
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    • 2004.05a
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    • pp.83-88
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    • 2004
  • First author proposed a proportioning method for member sections of a single layer reticulated dome subjected to uniform and non-uniform load without any geometrical initial imperfection, and discussed the validity and effectiveness of the method which was based on linear buckling stress and a knock down factor. However, buckling of a single layer reticulated dome is strongly affected by initial imperfection. It is well known that geometrical initial imperfections reduce the nonlinear buckling capacity of a single layer raticulated dome. Thus, structural engineers may be recommended to reflect the effects of geometrical initial imperfections in proportioning member sections. In this paper, firstly, the presented proportioning method by first author is applied to dome without consideration of any imperfections and the thickness and diameter of each member are determined. Secondly, the load bearing capacities of the proportioned domes are checked with the imperfection, by the inelastic buckling analysis.

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The Development of High Wind Velocity/High Drying Time Hair Dryer using Computational Fluid Dynamics Analysis Method (전산유체역학(CFD) 분석법을 이용한 High Wind Velocity/High Drying Time 헤어드라이어의 개발)

  • Park, Soo-Hong;Park, Jong-Chan
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.65 no.4
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    • pp.262-267
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    • 2016
  • This paper describes a design of a hair drier to improve its performance. the performance of the hair drier can be improved by increasing the wind velocity of its discharge port. the design of the hair drier is accomplished by using the CFD. the validity of design results were verified by comparison with the dry change of the hair drier. In this paper, the initial condition of the applied hair drier is as follows, the number of the blade is 9, the diameter of the suction port is 40[mm], the tip clearance is 12.5[mm], the con angle is $28.5^{\circ}$ and the fan angle is 27.5R. From design results, the enhanced condition of the hair drier can be obtained as follows, the number of the blade is 3, the diameter of the suction port is 50[mm], the tip clearance is 10.5[mm], the con angle is $21.5^{\circ}$ and the fan angle is 75R. At the enhanced condition of the hair drier, the wind velocity of the hair drier is 29[%] increase, and the dry time is 40[%] increase compare to the initial condition of the hair drier.

Behaviors of Mach Disk in Underexpanded Supersonic Moist Jet (초음속 습공기 제트에서 발생하는 마하디스크의 거동)

  • 백승철;김희동;권순범
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2003.05a
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    • pp.87-90
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    • 2003
  • It has been well known that the major feature of compressible flow fields might be different depending on their formation processes. The objectives of the present study is to investigates the effect of jet development on the time history of supersonic jet flow field, accompanying nonequilibrium condensation. Especially, the behaviors of Mach disk diameter and location in a supersonic moist air jet are presented in terms of nozzle pressure ratio and initial relative humidity. The relative humidity of moist air is controlled at the nozzle supply, and the nozzle pressure ratio is varied to obtain the moderately underexpanded flows at the exit of the nozzle, installed in an indraft wind tunnel. It is found that at the same pressure ratio the Mach disk diameter increases with the initial relative humidity, while moves further upstream. Furthermore, the values of Mach disk diameter and location for increasing pressure ratio show larger than those for increasing.

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