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Parametric Study of Dynamic Soil-pile-structure Interaction in Dry Sand by 3D Numerical Model (3차원 수치 모델을 이용한 건조사질토 지반-말뚝-구조물 동적 상호작용의 매개변수 연구)

  • Kwon, Sun-Yong;Yoo, Min-Taek
    • Journal of the Korean Geotechnical Society
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    • v.32 no.9
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    • pp.51-62
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    • 2016
  • Parametric studies for various site conditions by using 3d numerical model were carried out in order to estimate dynamic behavior of soil-pile-structure system in dry soil deposits. Proposed model was analyzed in time domain using FLAC3D which is commercial finite difference code to properly simulate nonlinear response of soil under strong earthquake. Mohr-Coulomb criterion was adopted as soil constitutive model. Soil nonlinearity was considered by adopting the hysteretic damping model, and an interface model which can simulate separation and slip between soil and pile was adopted. Simplified continuum modeling was used as boundary condition to reduce analysis time. Also, initial shear modulus and yield depth were appropriately determined for accurate simulation of system's nonlinear behavior. Parametric study was performed by varying weight of superstructure, pile length, pile head fixity, soil relative density with proposed numerical model. From the results of parametric study, it is identified that inertial force induced by superstructure is dominant on dynamic behavior of soil-pile-structure system and effect of kinematic force induced by soil movement was relatively small. Difference in dynamic behavior according to the pile length and pile head fixity was also numerically investigated.

Implementation of payment settlement system through Cyber Bank for Electronic Commerce (전자상거래용 사이버뱅크의 지불결제시스템 구축)

  • Kim, Moon-Shik;Lee, Eun-Seok
    • The KIPS Transactions:PartD
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    • v.15D no.1
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    • pp.121-130
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    • 2008
  • In line with the enhanced weight and variety of electronic commerce in business activities, new type of payment settlement and banking system which will enable to store, create and transfer values from the existing method of payment settlement is highly required. Cyber Banking system draws strong attention being the solution of there requirements. The existing Cyber Banking system has the difficulty of operation, administration, in addition to the problem of initial facility investment of big amount, resulted from the usage of the current business process. As the existing Cyber Bank system is unable to carry out the function of storing, creating, and transferring values due to the adoption conventional credit card system instead of the application of non-stop payment system between the seller and buyer. As a result, current Cyber Bank system still imply the deficiency of non-performing cash payment function on internet. This paper describes (1) an integrated application process, One Process One Input (OPOI) which is essential for software development of the Cyber Bank, (2) an application process of payment settlement system to be applied to the electronic commerce in Internet. And then, with these for a basis, (3) design and implementation of payment settlement system through CyberBank for Electronic Commerce. Consequently, by means of this suggested process, we could attempt to solve the problem of existing Cyber Bank system and further to explore the possibility of advanced Cyber Banking being the non-stop payment settlement system. The effectiveness of this suggested system has been practically confirmed.

Pharmacokinetic Evaluation of Ketorolac Tromethamine Sustained-Release Pellets after Oral Administration in Rabbits (케토롤락트로메타민 서방성 펠렛의 약물속도론적 평가)

  • Kwak, Son-Hyok;Hwang, Sung-Joo;Jiang, Ge;Nam, Kyung-Wan;Moon, Young-Girl;Lee, Hai-Bang;Cho, Sun-Hang;Yuk, Soon-Hong;Lee, Han-Koo;Jeong, Sang-Young;Lee, Young-Won
    • Journal of Pharmaceutical Investigation
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    • v.30 no.4
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    • pp.241-246
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    • 2000
  • To develop a sustained-release preparation containing ketorolac tromethamine, two sustained-release pellet formulations were evaluated with a pharmacokinetic study as compared with a conventional commercial tablets (10 mg $Tarasyn^{TM}$, Roche Korea Ltd.). Two sustained-release formulations were as follows; formulation A was composed of an inner layer containing 75% of drug coated with $Eudragit^{TM}$ RS 100 membrane and an outer layer containing 25% of drug mixed with $Eudragit^{TM}$ NE30D, and formulation B was composed of only an inner layer containing 100% of drug coated with $Eudragit^{TM}$ RS 100 membrane. The dissolution test was performed for two formulations. In case of conventional tablets, 2.5 mg of drug per a dose was administered orally into male Albino rabbit (2.0-2.3 kg of body weight) 3 times at intervals of 4 hours. In case of two sustained formulations, 7.5 mg of drug was administered once orally. Blood samples were withdrawn periodically after the administration, and the blood concentration was determined by HPLC. The conventional tablets showed very high peak-trough fluctuation between administered doses, but two sustained formulations showed less fluctuation. Formulation A with the loading dose showed the time to reach minimum effective concentration (MEC) i.e. the onset time was less than 20 min, while Formulation B had more than 1 hr of the onset time. Formulation A had the more constant plasma level than formulation B. However, formulation B had a time lag, so the plasma level was less than MEC for an initial period of 1 hr. In formulation A, the plasma level was maintained within the therapeutic window $(0.3-5\;{\mu}g/ml)$ for a long period. Formulation A was thought to be an ideal sustained-release formulation for ketorolac tromethamine oral delivery system.

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Effect of Barley Yellow Mosaic Virus (BaYMV)- Infested Soil on the Agronomic Characters of Three Different Barley Varieties

  • Hyun, Jong-Nae;Hong, Yeon-Kyu;Lim, Sea-Gyu;Kim, Yang-Gil;Kim, Mi-Jung;Lee, Mi-Ja;Lee, Key-Woon
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.53 no.4
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    • pp.427-433
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    • 2008
  • Barley Yellow Mosaic Virus (BaYMV) caused significant reduction in barley yield and is difficult to control due to alive parasitic soil-borne fungus, Palmyra gamines that transmits the, virus. Previous studies have indicated that a virus-free soil could be infested by using virus-contaminated farming machineneries and implements. For the further confirmation of this finding, different proportions of BaYMV-infested soil were mixed into virus free soil. Three barley varieties (Hordum vulgarae, cv "Olbori", "Baegdong" and "Sacheon 6") were sown in pots treated with different rate of P. graminis-infested soil ranging from 0% to 100% in October 20, 2001. Results showed that BaYMV infection increased as the rate of infested soil increased. Initial symptoms were observed in a pots treated with 10% infested soil in all the 3 varieties of barley. "Olbori" had about 5% infection in 20% infested soil and about 10% infection in 40% or 50% infested soil and about 20% infection in 60% infested soil. In "Baegdong", the trend of BYMV occurrence was similar with "Olbori" but the time of severe infection was earlier than "Olbori". BaYMV infection in "Sacheon 6" was even earlier than "Baegdong" with much more severe symptoms than "Baegdong". The growth rate of barley was affected by about 19-22% when grown in 20% infested soil. As the rate of BaYMV infested soil increased the heading date was delayed but the maturing date was early in "Olbori" and "Sacheon 6". Also, reduction rate of culm length in 3 varieties increased with increase of infested soil content. However, "Olbori" showed the highest reduction. "Sacheon 6", have been characterized with long spike length, however was significantly reduced as the infested soil increased. On the other hand, spike length of "Olbori" was not significantly affected despite of increased of infested soil. The reduction rate of 1000 kernel weight was higher in large kernel size cultivar "Sacheon 6" and "Olbori" than small kernel size "Baegdong" as increase of BaYMV-infested soil content.

Effects of Dietary Complex Probiotics on Growth Performance Nutrient Digestibility and Blood Characteristics in Growing Pigs (육성돈에 있어 복합생균제 첨가가 생산성, 영양소 소화율, 혈액성상 및 분뇨내 악취물질 발생량에 미치는 효과)

  • Yoo, Jong-Sang;Chen, Ying-Jie;Kim, In-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.8 no.5
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    • pp.1266-1272
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    • 2007
  • The current study was conducted to investigate the effects of dietary complex probiotics supplementation on growth performance, nutrient digestibility, blood characteristics and noxious gas emission of manure slurry in growing pigs. A total of forty eight pigs with an initial body weight of 20.12 kg were allotted to three dietary treatments (two pigs per pen with eight pens per treatment). Dietary treatment included: 1) CON (basal diet), 2) Pro1 (basal diet + 0.1% complex probiotics) and 3) Pro2 (basal diet + 0.2% complex probiotics). The experiment was lasted six weeks. Through the entire experimental period, ADG was increased with the increased complex probiotics supplementation level (linear effect, P<0.05). However, neither ADFI nor gain/feed was influenced by the dietary treatments. Complex probiotics supplementation increased DM digestibility (linear effect, P<0.05). Also, the N digestibility was improved, with the Pro1 treatment showed highest value (linear and quadratic effect, P<0.05). Supplementation of complex probiotics did not affect the WBC, RBC, lymphocyte and BUN concentrations in blood. The $NH_3-N$ emission from manure slurry was decreased with the increased level of complex probiotics supplementation (linear and quadratic effect, P<0.05). Similarly, $H_2S$ emission of manure slurry was also decreased significantly when complex probiotics was included in diet (linear effect, P<0.05). In conclusion, dietary supplementation of Complex probiotics can increase growth performance and decrease noxious gas emission of manure slurry in growing pigs.

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Synthesis and Characterization of Heat Resistant Organophilic Layered Silicate Modified with Oligo(amic acid)s Having Alkyl Side Chains and Their Nanocomposites (알킬기가 도입된 올리고 아믹산 구조를 가진 고내열 친유기 층상 실리케이트의 제조 및 이를 이용한 나노복합재의 특성평가)

  • Han Ji Yun;Won Jong Chan;Lee Jae Heung;Suh Kyung-Do;Kim Yong Seok
    • Polymer(Korea)
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    • v.29 no.5
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    • pp.451-456
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    • 2005
  • In the field of designing of nano-fillers of polyimide nanocomposites, the two strategic points are the heat-resistance and compatibility with polyimide, a matrix polymer. In this study, we designed oligo(amic acid) having alkyl side chains and terminal amine groups to satisfy previous requirements and studied the modification of surface of layered silicates. Oligo(amic acid)s were prepared by the reaction of diamine monomers and PMDA and their molecular weight was controlled in about 2000g/mol. After that, acidification and ion exchange reaction led to the high-temperature organophilic layered silicate (OLS). XRD pauerns of OLS showed the more increased gallery spacing by $4{\AA}$ than that of the pristine layered silicate and the initial decomposition temperatures of OLS were in above $280^{\circ}C$. The polyimide nanocomposite films based on heat resistant OLS showed that the OLSs were well dispersed through the matrix and their CTEs showed a decrease of $26\%$ compared with pristine polyimide films.

Preparation and Characterization of Zaltoprofen-Loaded Polyoxalate Microspheres for Control Release (방출제어를 위한 잘토프로펜이 함유된 폴리옥살레이트 미립구의 제조와 특성)

  • Kim, Kyoung Hee;Lee, Cheon Jung;Jo, Sun A;Lee, Jung Hwan;Jang, Ji Eun;Lee, Dongwon;Kwon, Soon Yong;Chung, Jin Wha;Khang, Gilson
    • Polymer(Korea)
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    • v.37 no.6
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    • pp.702-710
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    • 2013
  • Zaltoprofen loaded polyoxalate (POX) microspheres were prepared by an emulsion solvent-evaporation/extraction method like oil-in-water (O/W) for sustained release of zaltoprofen. The influence of several preparation parameters such as fabrication temperature, stirring speed, intensity of the sonication, initial drug ratio, molecular weight ($M_w$) of POX, concentration of POX and concentration of emulsifier has been investigated on the zaltoprofen release profiles. Physicochemical properties and morphology of zaltoprofen loaded POX microspheres were investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD), differential scanning calorimeter (DSC) and Fourier transform infrared (FTIR). Through the analyzed results, it was demonstrated that the characteristics of the microspheres greatly affected by the prepared condition. The releases behavior of zaltoprofen was investigated for 10 days in vitro. It was confirmed that the release behavior of zaltoprofen can be controlled by the manufacturing factor of solvent-evaporation/extraction method.

Dietary Effect of Silk Protein on Colon Cancer of Animal (실크 단백질 식이공급이 동물대장암에 미치는 영향)

  • Yeo, Joo-Hong;Lee, Kwang-Gill;Woo, Soon-Ok;Kweon, Hae-Yong;Han, Sang-Mi;Park, Kyung-Ho;Kim, Sung-Su
    • Journal of Sericultural and Entomological Science
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    • v.49 no.2
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    • pp.67-70
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    • 2007
  • This study was done for the dietary effect of silk protein, molecular controlled silk sericin and silk fibroin, on colon cancer of animal. The ICR mice were given weekly injections of 1,2-dimethylhydrazine (DMZ) for the initial 10 mg/kg with four weeks, and fed a diets supplemented with 3% (v/v) molecular controlled sericin and fibroin for 6 weeks, respectively. Then, the body weight, efficiency of dietary, typical histologic appearance of animal colon tissue and COX-2 effect were studied, too. Molecular controlled sericin protein are shown more higher dietary effect on animal colon cancer than fibroin supplemental case. The results suggest a potential usefulness of sericin as a chemopreventive for colon carcinogenesis and the development functional food.

Effects of fallen blossoms of Prunus spp. on nutrient dynamics in an artificial pond ecosystem (벚나무류 낙화가 인공 연못생태계의 물질순환에 미치는 영향)

  • Lee, Bo Eun;Jeon, Young Joon;Jang, You Lim;Kim, Jae Geun
    • Journal of Wetlands Research
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    • v.17 no.2
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    • pp.203-208
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    • 2015
  • To identify the effect of fallen cherry blossom on the artificial pond ecosystem, microcosm experiment was conducted into the aquatic decomposition of Prunus species petals. Petals were put in $1mm^2$ mesh nylon litter bags. For treatment group, one flower litter bag was placed into each pot microcosm ($27{\times}20{\times}8cm^3$) filled with influent water from the artificial pond, whereas control group microcosm contained pond water only. Decomposition time were set differently (4, 8, 12, 16 days) among treatment groups. At the end of experiment, most petals were decomposed and only 32.3% of initial dry weight remained with the decay rate (k) of $7.06{\times}10^{-2}day^{-1}$. $NO_3-N$ concentration of microcosm water decreased sharply from 1.90 mg/L at first to 0.02 mg/L, whereas $NH_4-N$ concentration increased from 0.03 mg/L to 2.85 mg/L continually. $PO_4-P$ concentration was 0.03 mg/L at first and increased to 2.39 mg/L by decomposition. Therefore, available phosphorus seems to have leached with higher rate than nitrogen from the petals litter. Increase about 0.02 mg/L in $PO_4-P$ concentration could be estimated in artificial pond from the calculation on the total quantity of fallen blossoms. This result suggests that available phosphorus from the decomposed Prunus petals could cause eutrophication in the artificial pond.

Clinical Analysis of Pelvic Fracture in 54 Dogs (54두 개에서 발생한 골반 골절의 임상적 분석)

  • Kim, Kyung-Hee;Lee, Jong-Hoon;Yoon, Hun-Young;Jeong, Soon-Wuk
    • Journal of Veterinary Clinics
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    • v.28 no.5
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    • pp.467-472
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    • 2011
  • This study was conducted to describe clinical presentation of pelvic fracture and compare clinical outcomes of each part of pelvic fractures in 54 client-owned dogs. There was an average of 3.61 pelvic fractures per dog and 47 dogs had more than two fractures. The average time until initial weight-bearing on the affected leg, hospitalization after surgery, and lameness score at final check in 31 dogs that underwent surgery were 7.04 days, 16.39 days, and 1.25, respectively, and there were no significant difference in the incidence of sacroiliac luxation, iliac fracture, and acetabular fracture among them. The length of hospitalization and the lameness score upon final check of the dogs with over two surgically repaired sites were significantly longer and higher than those of the dogs with one surgically repaired site (P = .043 and P = .008, respectively). Upon final check of the dogs with bilateral pelvic fracture that was surgically treated, the hospitalization and lameness score were significantly longer and higher than those of dogs with unilateral pelvic fracture that was surgically treated (P = .034 and P = .033), respectively. The number of pelvic fractures treated surgically appears to be a more influential factor influencing recovery from pelvic fractures than the location of the pelvic fractures.