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Immunization Practices in Children with Renal Disease : A Survey of the Members of Korean Society of Pediatric Nephrology (신질환 소아의 예방접종 현황 : 대한소아신장학회 회원들의 접종 방식에 대한 조사)

  • Park Seong-Shik;Ahn Sung-Ryou;Lee Ju-Suk;Kim Su-Yung
    • Childhood Kidney Diseases
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    • v.6 no.2
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    • pp.198-208
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    • 2002
  • Purpose : There is no scientific basis for an immunization policy for children with renal disease who have increased risk of infection in Korea. As an initial step in approaching this problem, this survey of pediatric nephrologists was undertaken to determine the current recommendations of practicing pediatric nephrologists Methods : Questionnaires were sent to the members of Korean Society of Pediatric Nephrology via mail and E-mail. The questionnaire was designed to obtain information about the immunization practice of basic vaccination schedule for nephrotic syndrome, the side effects after vaccination and the immunization practice about recommended vaccines for children with renal disease. Results : Questionnaires were sent to 56 pediatric nephrologists. 35 replies were received (response rate: 62.5%). Almost of the respondents (82.8%) reported practicing at university hospital. All respondents reported modified vaccination schedule. 65.7% of the respondents immunized nephrotic children with live vaccines some time later after discontinuation of corticosteroids treatment and 57.1% of respondents immunized them with killed vaccines during medication of low doses of corticosteroids. Respondents experienced relapse of nephrotic syndrome after vaccination are nine, lack of vaccine efficacy are three and infection by organisms of live vaccines are two. 71.4% of respondents reported vaccinating children with renal disease for hepatitis B, pneumococcus and influenza during medication of low doses of corticosteroids. But There is few difference of the rates of respondents vaccinating them for Hemophilus influenzae type b between during medication of low doses of corticosteroids and after discontinuation of corticosteroids treatment (45.7% us 42.9%). Almost of respondents reported vaccinating renal failure children without immunosuppression for hepatitis B, pneumococcus, influenza and H. influenzae type b ($54.3{\sim}77.1%$). Conclusion : Pediatric nephrologists practiced modifying vaccination schedules for children with renal disease in Korea and there was variation according to the progression of disease and the doses of corticosteroids. It is necessary to establish the immunization guideline for children with renal disease through the prospective studies.

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Response of the Growth and Root Development of Shade Landscape Plants by Slit Ventilation Treatment into Indoor Container (실내용기 내 슬릿(Slit)처리가 내음성 조경식물의 생육과 뿌리발달에 미치는 영향)

  • Ju, Jin-Hee;Han, Jung-Hwa
    • Journal of the Korean Institute of Landscape Architecture
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    • v.37 no.3
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    • pp.105-112
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    • 2009
  • This study has attempted to facilitate various new technologies related to indoor containers and develop a desirable planting environment after investigating the growth (including root growth) of shade-tolerant landscape plants under slit processing, a natural indoor ventilation system. The following results were found: In terms of the shoot growth of Fatsia japonica in a slit container, no distinctive difference was observed in comparison with the control group. However, growth was good when the container 250mm tall or taller. Therefore, it was verified that optical soil depth is more important than slit processing in shoot growth of Fatsia japonica. In Fatsia japonica root length was observed as follows: Control 2(250mm) > Slit 2(250mm) > Control 1(195mm) > Slit 3(360mm) > Control 3(360mm) > Slit 1(195mm). The largest growth was observed in Control 2(250mm), which had no slit processing. In term of root width, this was lower than the initial value in all groups, which means that the root grew vertically, not horizontally. In terms of plant height of Ophiopogon japonicus, a gradual increase was observed in the control group that had no slit processing. No significant growth was detected in the slit system, however. In terms of shoot number, slit containers were generally higher than the control group. In terms of fresh and dry weights, on the contrary, slit containers were mostly lower than the control group. In Ophiopogon japonicus, root length was observed as follows: Slit 2(250mm) > Slit 1(195mm) > Control 2(250mm) > Control 3(360mm) > Slit 3(360mm) > Control 1(195mm). In Ardisia japonica, slit containers were mostly greater than control group in terms of plant height. The greatest plant height was observed at Slit 2(250mm) instead of Slit 1(195mm) and Slit 3(360mm). Except for plant height and shoot number, however, no significant shoot and root growth was observed. Root length was observed as follows: Slit 2(250mm) > Slit 3(360mm) > Control 3(360mm) > Slit 1(195mm) > Control 2(250mm) > Control 1(195mm). Therefore, root length in slit containers was mostly greater than in the control group. The width of root, however, declined in general.

Effect of Brown Seaweed Waste Supplementation on Lactational Performance and Endocrine Physiology in Holstein Lactating Cows (미역부산물의 첨가가 홀스타인 비유우의 비유성적과 내분비생리에 미치는 영향)

  • Lee, H.G.;Hong, Z.S.;Li, Z.H.;Xu, C.X.;Jin, X.;Jin, M.G.;Lee, H.J.;Choi, N.J.;Koh, T.S.;Choi, Yun-Jaie
    • Journal of Animal Science and Technology
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    • v.47 no.4
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    • pp.573-582
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    • 2005
  • This study was conducted to investigate effects of the brown seaweed waste(BSW) supplementation on milk production and related endocrine response in serum in Holstein dairy cows. A total of 14 Holstein dairy cows(initial mean live weight 625kg, average lactation days 225, Reproduction 2.4) were randomly allocated into control(basal diet) and treatment groups (4% BSW/basal diet) with 7 replications for 90 days. Dry matter intake was not affected by brown seaweed waste supplementation, but daily milk yield(kg) at the last experiment significantly increased (6.25kg) in treatment group compared with control group(p<0.05) at the last experiment. The plasma insulin-like growth factor(IGF)-1, triiodothyronine($T_3$) and thyroxine($T_4$) levels were significantly increased in treatment group compared with control group(p<0.05), although the concentration of plasma growth hormone(GH) was not significantly different. Milk composition was not significantly different between groups. The somatic cell count(SCC) in milk were significantly reduced in treatment group compared with control group(p<0.05), but antibodies(total IgG, G1, G2) were not significantly different between groups. Therefore we strongly believe that the increased milk yield is related to metabolic hormones as IGF-1, $T_3$ and $T_4$ and the mechanism of reducing SCC in milk must do more study related nonspecific immunsystem in the future.

Fermentation Property of Chinese Cabbage Kimchi by Fermentation Temperature and Salt Concentration (발효온도 및 소금농도에 따른 배추김치의 발효 특성)

  • Chang, Moon-Jeong;Kim, Myung-Hwan
    • Applied Biological Chemistry
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    • v.43 no.1
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    • pp.7-11
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    • 2000
  • The effects of fermentation temperature$(0{\sim}l5^{\circ}C)$ and salt concentration$(1.5{\sim}4.0%)$ on the fermentation property of Chinese cabbage Kimchi were analyzed by response surface methodology. The pH decreased and acidity increased with increasing fermentation time. The reduction and increment velocities of pH and acidity were increased by increasing fermentation temperature and decreasing salt concentration. The optimum pH 4.2 was reached within $14{\sim}24$ days at $5{\sim}15^{\circ}C$, while pHs of 24 days at $0{\sim}5^{\circ}C$ were still lower value than 4.2. The effect of salt concentration more affected terminal fermentation period than initial fermentation period. The maximum edible acidity, 0.75%, was reached within 8 days at $15^{\circ}C$, while acidifies of 24 days at $0^{\circ}C$ were $0.35{\sim}0.43%$. The effects of salt concentration at $0^{\circ}C$ was higher than those at $15^{\circ}C$. The fermentation time, fermentation temperature and salt concentration were the first, second and third affecting factors on the pH and acidity of Kimchi. Based on the coefficients of determination, pH and acidity were highly fitted to the experimental data$(r^2>0.9276)$. For the suitable acidity range, $0.40{\sim}0.75%$, the edible period of Kimchi at $15^{\circ}C,\;10^{\circ}C\;and\;5^{\circ}C$ were 4 days, 10 days and 18 days at the 2.75% of salt concentration, respectively. The edible period increased from 14 days to 19 days with increased salt concentration from 1.50% to 4.00% at $5^{\circ}C$ of fermentation temperature.

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Local Control and Survival in Radiation Treatment of Locally Advanced Non-Small Cell Lung Cancer (III 병기 비소세포성 폐암의 방사선 치료성적)

  • Song, Mi-Hee;Yong, Jin-Young;Oh, Won-Young;Yoo, Nam-Soo;Whang, In-Soon
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.311-319
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    • 1993
  • The retrospective analysis was performed on 37 patients with stage III non small cell lung cancer who received the radiotherapy from Feb. 1986 to Dec. 1990 at the Dept. of Radiation Oncology, National Medical Center. This analysis, with 29 patients $(78.4\%)$ having been followed from 10 to 60 months, was done to know the survival rate and significant prognostic factor. The actuarial 2,5-year survival rates were $20.6\%,6.9\%$ in our all patients and median survival time was 10 months. Of patients with KPS (Karnofsky prformance status) greater than $80\%,$ the 2, 5 year survival rate and median survival time were $29.2\%,9.7\%$ and 13 months, respectively. The 2-year survival rate and median survival time of patients with KPS less than $80\%\;were\;13.7\%$ and 7 months, respectively. The survival difference according to performance status was statisticaly significant $(29.2\%\;vs.\;13.7\%)(p<0.05).$ In stage IIIa, the 2,5-year survival rate and median survival rate and median survival time were $29.2\%,9.7\%$ and 12 months, respectively. The 2-year survival rate and metian survival time of stage IIIb were $8.6\%$ and 10 months, respectively. The survival difference between stage IIIa and IIIb did not show statistical significance (p>0.1). Of the prognostic factors, the difference of survival rate by initial performance status was statistically significant (p<0.05). But the difference of survival rates by pathologic cell type, stage, total radiation dose, radiotherapy response, and cmbination with chemotherapy were not statistically significant.

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Determination of Target Clean-up Level and Risk-Based Remediation Strategy (위해성에 근거한 정화목표 산정 및 복원전략 수립)

  • Ryu, Hye-Rim;Han, Joon-Kyoung;Nam, Kyoung-Phile
    • Journal of Soil and Groundwater Environment
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    • v.12 no.1
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    • pp.73-86
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    • 2007
  • Risk-based remediation strategy (RBRS) is a consistent decision-making process for the assessment and response to chemical release based on protecting human health and the environment. The decision-making process described integrates exposure and risk assessment practices with site assessment activities and remedial action selection to ensure that the chosen actions are protective of human health and the environment. The general sequences of events in Tier 1 is as follows: initial site assessment, development of conceptual site model with all exposure pathways, data collection on pollutants and receptors, and identification of risk-based screening level (RBSL). If site conditions do not meet RBSL, it needs further site-specific tier evaluation, Tier 2. In most cases, only limited number of exposure pathways, exposure scenarios, and chemicals of concern are considered the Tier 2 evaluation since many are eliminated from consideration during the Tier 1 evaluation. In spite of uncertainties due to the conservatism applied to risk calculations, limitation in site-specific data collections, and variables affecting the selection of target risk levels and exposure factors, RBRS provides us time- and cost-effectiveness of the remedial action. To ensure reliance of the results, the development team should consider land and resource use, cumulative risks, and additive effects. In addition, it is necessary to develop appropriate site assessment guideline and reliable toxicity assessment method, and to study on site-specific parameters and exposure parameters in Korea.

Impact of Sulfur Dioxide Impurity on Process Design of $CO_2$ Offshore Geological Storage: Evaluation of Physical Property Models and Optimization of Binary Parameter (이산화황 불순물이 이산화탄소 해양 지중저장 공정설계에 미치는 영향 평가: 상태량 모델의 비교 분석 및 이성분 매개변수 최적화)

  • Huh, Cheol;Kang, Seong-Gil;Cho, Mang-Ik
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.13 no.3
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    • pp.187-197
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    • 2010
  • Carbon dioxide Capture and Storage(CCS) is regarded as one of the most promising options to response climate change. CCS is a three-stage process consisting of the capture of carbon dioxide($CO_2$), the transport of $CO_2$ to a storage location, and the long term isolation of $CO_2$ from the atmosphere for the purpose of carbon emission mitigation. Up to now, process design for this $CO_2$ marine geological storage has been carried out mainly on pure $CO_2$. Unfortunately the $CO_2$ mixture captured from the power plants and steel making plants contains many impurities such as $N_2$, $O_2$, Ar, $H_2O$, $SO_2$, $H_2S$. A small amount of impurities can change the thermodynamic properties and then significantly affect the compression, purification, transport and injection processes. In order to design a reliable $CO_2$ marine geological storage system, it is necessary to analyze the impact of these impurities on the whole CCS process at initial design stage. The purpose of the present paper is to compare and analyse the relevant physical property models including BWRS, PR, PRBM, RKS and SRK equations of state, and NRTL-RK model which are crucial numerical process simulation tools. To evaluate the predictive accuracy of the equation of the state for $CO_2-SO_2$ mixture, we compared numerical calculation results with reference experimental data. In addition, optimum binary parameter to consider the interaction of $CO_2$ and $SO_2$ molecules was suggested based on the mean absolute percent error. In conclusion, we suggest the most reliable physical property model with optimized binary parameter in designing the $CO_2-SO_2$ mixture marine geological storage process.

Mineral Leaching from Air-Dried Forages (마른 목초(牧草) 잎으로 부터의 무기물(無機物) 용출(溶出))

  • Kim, S.D.;YOSHIDA, Shigekata
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.19 no.3
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    • pp.265-272
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    • 1999
  • In this study in order to know the behavior of mineral nutrients from forage plant to soil in a grassland ecosystem, the leaching of minerals (K, Mg, Ca, N and P) from air-dried (dead) plant body was investigated by putting orchardgrass (Dactylis glomerata L.) hay on meadow during a month with seasonal changes. The results obtained were as follows; 1) The K content of the forage, not stable during the experimental seasons, tended to decrease in the summer of 1986, while the Mg and Ca contents increased in the summer. The reason might be a different response (solubility or leaching liability) of the monovalent mineral (K) and divalent ones (Mg and Ca) in the forage to rainfall. 2) The percentage of P to the initial amount in the forage showed larger decrease in a rainy period (Feb.~Mar., 1986) and during the rainy summer (May to July). The P component of the forage might be easily leached with water. 3) The percentage of the four minerals (Ca, N, Mg, K) remained the least in the period of (Jun.~Jul., 1986), 4) Though the percentage of remained Mg and N of the forage varied very similarly, the percentage of remained N was higher than that of Mg during periods before summer (January to May), while after the period the ratio of the Mg seemed to be higher than that of the N (June to December), 5) During the periods until (May~Jun., 1986) the percentage of remained K and P of the forage varied in very similar pattern, and the order of remained mineral was as follows; $Ca>N{\geq}Mg>P=K$. But from the period of (Jun-Jul) the ratio of P remained in the forage increased nearly up to the ratio of N, and the order was as follows; $Ca>Mg{\geq}N{\geq}P>K$.

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Elementary School Teachers' Perception of Gifted Education (영재교육에 대한 초등학교 교사들의 인식)

  • Choi, Moon-Kyung;Park, Jung-Ok
    • Journal of Gifted/Talented Education
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    • v.14 no.4
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    • pp.125-149
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    • 2004
  • The purpose of this study is to provide basic information on the current status of elementary school teachers' perception of gifted education. For this purpose, this study wi1l analyze elementary school teachers' perception of the gifted education (i.e., general perception of gifted education, characteristics of gifted children, identification of gifted children, programs for gifted education, and teachers of gifted education). A questionnaire survey was used for the purpose and research questions of this study. The questionnaire used in this study was constructed by taking into account the results of surveys conducted in previous studies and the literature on gifted education. Before conducting the research, a preliminary inquiry was made to identify problems that may occur while the subjects were participating in the survey, as well as to determine the appropriateness of the questionnaire and the amount of time needed. The preliminary inquiry was conducted with ten randomly selected elementary school teachers who did not participate as subjects in the actual research. The results were later used as initial data for the actual research. The subjects of this study were teachers who were teaching in8 elementary schools under each office of education in Seoul. This process was conducted for 180 elementary school teachers from April to May 2004. The results were analyzed using SPSS (Statistical Package for Social Science) Ver. 10.1, a software program for statistical research. After the data were analyzed, the following conclusions were arrived at: 1. The result of the genera1 perception of gifted education by elementary school teachers were positive and reasonably high. The level of their perception of detailed information or knowledge, however, was relatively low. 2. As for their perceptions of the emotional characteristics of gifted children, t11e results showed a low level of understanding of the characteristics of gifted children. 3. As for their perceptions of identification of gifted children, the results showed a high level of understanding of the appropriate time to provide special education to gifted children and of the methods to identify such. On the other hand, their understanding of the identification of gifted children in an actual class was poor. 4. The respondents' level of perceptions of programs for gifted education was very low since many subjects did not have any experiences with such programs. 5. The results showed a very positive response to receiving training on gifted education, though they were very reluctant to be assigned as teachers of gifted education because of the excessive work that is associated with such and their lack of capability in handling gifted children.

Enhanced Production of Cellobiase by a Marine Bacterium, Cellulophaga lytica LBH-14, in Pilot-Scaled Bioreactor Using Rice Bran (파이롯트 규모에서 미강을 이용한 해양미생물 Cellulophaga lytica LBH-14 유래의 cellobiase 생산)

  • Cao, Wa;Kim, Hung-Woo;Li, Jianhong;Lee, Jin-Woo
    • Journal of Life Science
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    • v.23 no.4
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    • pp.542-553
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    • 2013
  • The aim of this work was to establish the optimal conditions for the production of cellobiase by a marine bacterium, Cellulophaga lytica LBH-14, using response-surface methodology (RSM). The optimal conditions of rice bran, ammonium chloride, and the initial pH of the medium for cell growth were 100.0 g/l, 5.00 g/l, and 7.0, respectively, whereas those for the production of cellobiase were 91.1 g/l, 9.02 g/l, and 6.6, respectively. The optimal concentrations of $K_2HPO_4$, NaCl, $MgSO_4{\cdot}_{7H2}O$, and $(NH_4)_2SO_4$ for cell growth were 6.25, 0.62, 0.28, and 0.42 g/l, respectively, whereas those for the production of cellobiase were 4.46, 0.36, 0.27, and 0.73 g/l, respectively. The optimal temperatures for cell growth and for the production of cellobiase by C. lytica LBH-14 were 35 and $25^{\circ}C$, respectively. The maximal production of cellobiase in a 100 L bioreactor under optimized conditions in this study was 92.3 U/ml, which was 5.4 times higher than that before optimization. In this study, rice bran and ammonium chloride were developed as carbon and nitrogen sources for the production of cellobiase by C. lytica LBH-14. The time for the production of cellobiase by the marine bacterium with submerged fermentations was reduced from 7 to 3 days, which resulted in enhanced productivity of cellobiase and a decrease in its production cost. This study found that the optimal conditions for the production of cellobiase were different from those of CMCase by C. lytica LBH-14.