Journal of Animal Science and Technology

Korean Society of Animal Sciences and Technology (한국축산학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Brown Seaweed Waste Supplementation on Lactational Performance and Endocrine Physiology in Holstein Lactating Cows

미역부산물의 첨가가 홀스타인 비유우의 비유성적과 내분비생리에 미치는 영향

  • Lee, H.G. (School of Agricultural Biotechnology, Seoul National University) ;
  • Hong, Z.S. (School of Agricultural Biotechnology, Seoul National University) ;
  • Li, Z.H. (School of Agricultural Biotechnology, Seoul National University) ;
  • Xu, C.X. (School of Agricultural Biotechnology, Seoul National University) ;
  • Jin, X. (School of Agricultural Biotechnology, Seoul National University) ;
  • Jin, M.G. (School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, H.J. (National Livestock Research Institute, R.D.A.) ;
  • Choi, N.J. (National Livestock Research Institute, R.D.A.) ;
  • Koh, T.S. (Animal Husbandry, Konkuk University) ;
  • Choi, Yun-Jaie (School of Agricultural Biotechnology, Seoul National University)
  • 이홍구 (서울대학교 농생명공학부) ;
  • 홍중산 (서울대학교 농생명공학부) ;
  • 이철호 (서울대학교 농생명공학부) ;
  • 허성웅 (서울대학교 농생명공학부) ;
  • 김훈 (서울대학교 농생명공학부) ;
  • 김명국 (서울대학교 농생명공학부) ;
  • 이현준 (농촌진흥청 축산기술연구소) ;
  • 최낙진 (농촌진흥청 축산기술연구소) ;
  • 고태송 (건국대학교 축산대학) ;
  • 최윤재 (서울대학교 농생명공학부)
  • Published : 2005.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

This study was conducted to investigate effects of the brown seaweed waste(BSW) supplementation on milk production and related endocrine response in serum in Holstein dairy cows. A total of 14 Holstein dairy cows(initial mean live weight 625kg, average lactation days 225, Reproduction 2.4) were randomly allocated into control(basal diet) and treatment groups (4% BSW/basal diet) with 7 replications for 90 days. Dry matter intake was not affected by brown seaweed waste supplementation, but daily milk yield(kg) at the last experiment significantly increased (6.25kg) in treatment group compared with control group(p<0.05) at the last experiment. The plasma insulin-like growth factor(IGF)-1, triiodothyronine($T_3$) and thyroxine($T_4$) levels were significantly increased in treatment group compared with control group(p<0.05), although the concentration of plasma growth hormone(GH) was not significantly different. Milk composition was not significantly different between groups. The somatic cell count(SCC) in milk were significantly reduced in treatment group compared with control group(p<0.05), but antibodies(total IgG, G1, G2) were not significantly different between groups. Therefore we strongly believe that the increased milk yield is related to metabolic hormones as IGF-1, $T_3$ and $T_4$ and the mechanism of reducing SCC in milk must do more study related nonspecific immunsystem in the future.

본 시험은 미역분말의 첨가가 홀스타인 젖소의 유생산과 내분비계에 미치는 영향을 규명하기 위하여 실시하였다. 기초사료에 미역분말을 1일 두당 800g 수준으로 급여하여 대조구와 비교하였다. 사료건물섭취량은 처리에 의한 영향을 받지 않았고 비유말기 산유량은 대조구에 비해 일일 6.25kg 이나 많게 유의하게 증가하였다(p<0.05). 하지만 유성분은 처리구간에 유의한 차이를 나타내지 않았다. 대조구의 체세포수는 유동적이었지만 처리구의 체세포수는 시험 종료 시 $10^5$개/ml로 시험개시에 비해 무려 53.77%의 감소효과를 보여 탁월한 체세포 감소효과를 나타내었다. 미역분말의 첨가가 혈중 면역글로부린의 함량에는 영향을 주지 않은 것으로 나타났다. 비유에 직접적인 영향을 미치는 IGF-1의 혈장농도는 미역처리구에서 유의성 있게 증가하였으며 비유와 직접적인 관련이 있는 또 다른 호르몬인 $T_3$ 와 $T_4$의 농도도 유의적으로 증가하는 양상을 나타내었다. 지질대사산물인 TC, HDL-C와 LDL-C의 농도는 모두 처리구에서 증가하는 양상을 나타냈다. 이와 같이 미역부산물의 사료 중 첨가는 유생산량의 증가를 보였는데 이는 혈중 비유관련 호르몬의 분비에 영향을 준 결과로 확인된 바 젖소사료자원으로서의 응용가치가 클 것으로 사료된다.

Keywords

References

  1. Allen, V. G., Pont, K. R., Saker, K. E., Fontenot, J. P., Bagley, C. P., Ivy, R L., Evans, R R, Sclunidt, R E., Fike, J. H, Zhang, X., Ayad, J. Y, Brown, C. P., Miller, M. F., Montgomery, J. L., Mahan, J., Wester, D. B. and Melton, C. 2001. Tasco: Influence of a brown seaweed on antioxidants in forages and livestock-A review. J. Anim. Sci. 79(E. Suppl.):E21-E31 https://doi.org/10.2527/jas2001.79E-SupplE21x
  2. Channon, J. Y. and Leslie, C. C. 1990. A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7. J. Biol. Chem. 26(10):5409-5413
  3. Cohick, W. S. 1998. Role of the insulin-like growth factors and their binding proteins in lactation. J. Dairy Sci. 81(6):1769-77 https://doi.org/10.3168/jds.S0022-0302(98)75746-7
  4. Daughaday, W. H., Mariz, I. K. and Blethen, S. L. 1980. Inhibition of assess of bound somatomedin to membrane receptor and immunobinding sites: A comparision of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol extraction serum. J. Clin. Endocrinol. Metab. 51:781-788 https://doi.org/10.1210/jcem-51-4-781
  5. Franklin, S. T., Martin, K. R, Baer, R. J., Schingoethe, D. J. and Hippen, A. R 1999. Dietary marine algae(Schizochytrium sp.) increases concentrations of conjugated linoleic, docosahexaenoic and transvaccenic acid in milk of dairy cows. J. Nutr. 129:2048-2052 https://doi.org/10.1093/jn/129.11.2048
  6. Hadley, Mac. E. 1996. Endocrinology(Fourth edition). Prentice-Hall International, Inc
  7. Iwamoto, Y., Xu, X., Tamura, T., Oda, T. and Muramatsu, T. 2002. Enzymatically depolymerized alginate oligomers that cause cytotoxic cytokine production in human mononuclear cells. Biosci Biotechnol Biochem. 67(2): 258-263 https://doi.org/10.1271/bbb.67.258
  8. Keys, A., Grande, F. and Anderson, J. T. 1961. Fibers and pectin in the diet and serum cholesterol concentration in man. Proceeding of the Society of experimental biological medicine. 106:555-558 https://doi.org/10.3181/00379727-106-26401
  9. Kimura, Y, Watanabe, K. and Okuda, H. 1996. Effect of soluble sodium alginate on cholesterol excretion and glucose tolerance in rats. J. Ethnophar. macology. 54(1996):47-54 https://doi.org/10.1016/0378-8741(96)01449-3
  10. Kooijman, R, Rijkers, G. T. and Zegers, B. J. 1996. IGF-1 potentiates IL-2 production in human peripheral T cell. Journal of Endocrinology. 149:351-356 https://doi.org/10.1677/joe.0.1490351
  11. Lee, H G., Vega, L. T., Phung, L. T., Matsunaga, N., Kuwayama, H. and Hidari, H. 2000. The effect of growth hormone-releasing peptide-2(KP 102) administration on plasma insulin-like growth factor( IGF)-1 and IGF-binding proteins in Holstein steers on different planes of nutrition. Domestic Animal Eendocrinology. 18:293-308 https://doi.org/10.1016/S0739-7240(00)00051-5
  12. Lee, H G., Choi, Y. J., Lee, S. R, Kuwayama, H, Hidari, H and You, S. K 2005. Effects of dietary protein and growth hormone-releasing peptide(GHRP-2) on plasma IGF-1 and IGFBPs in Hosltein steers. Domestic Animal Endocrinology. 28:134-146 https://doi.org/10.1016/j.domaniend.2004.07.001
  13. Lina, Yonekura., Hiroo, Suzuki. 2003. Some polysaccharides improve zinc bioavailability in rats fed a phytic acid-contaning diet. Nutrition Research. 23(2003):343-355 https://doi.org/10.1016/S0271-5317(02)00538-9
  14. Montserrat, G. U. and Isabel, G. 2002. Bioavailability of nutrients in rats fed on edible seaweeds, nori (Porphyra tenera) and wakame(Undaria pinnatijida), as a source fo dietary fiber. Food Chemistry. 76:281-286 https://doi.org/10.1016/S0308-8146(01)00273-4
  15. Nishino, T., Fukuda, A, Nagumo, T., Fujihara, M. and Kaji, E. 1999. Inhibition of the generation of thrombin and factor Xa by a fucoidan from the brown seaweed Ecklonia kurome. Thrombosis Research 96: 37-49 https://doi.org/10.1016/S0049-3848(99)00060-2
  16. Nishino, T., Yamauchi, T., Horie, M., Nagurno, T. and Suzuki I, H. 2000. Effects of a fucoidan on the activation of plasminogen by u-PA and t-PA Thrombosis Research 99:623-634 https://doi.org/10.1016/S0049-3848(00)00289-9
  17. NRC. 2001. Nutrient requirements of dairy cattle 7th revised edition. National academy press, Washington, DC
  18. Pattanaik, A K., Khan, S. A, Varshney, V. P. and Bedi, S. P. S. 2001. Effect of iodine level in mustard (Brassica juncea) cake-based concentrate supplement on nutrient utilization and serum thyroid hormones of goats. Small Ruminant Research. 41:51-59 https://doi.org/10.1016/S0921-4488(01)00192-4
  19. Schwartz, Y., Goodman, H. M. and Yamaguchi, H. 1991. Refractoriness to Growth Hormone is Associated with Increased Intracellular Calcium in Rat Adipocytes. Proc. Natl. Acad. Sci. U. S. A 88. 6790-6794 https://doi.org/10.1073/pnas.88.15.6790
  20. Sethi, V. and Kapil, U. 2004. Iodine deficiency and development of brain. Indian J. Pediatr. 71(4): 325-9 https://doi.org/10.1007/BF02724099
  21. Thissen, J. P., Ketelslegers, J. M. and Louis, E. U. 1994. Nutritional regulation of the Insulin-like growth factors. Endocrine Reviews. 15:80-101
  22. Toilet, P. E. B. and Mode, A 1990. Growthhormone (GH) regulation of cytochrome P-450IIC12, insulinlike growth factor-I (IGF-1), and GH receptor messenger RNA expression in primary rat hepatocytes: a hormonal interplay with insulin, IGF-1, and thyroid hormone. Mol Endocrinol 4:1934-1942 https://doi.org/10.1210/mend-4-12-1934
  23. Toilet, P. H. M., Gustafsson, J. A and Mode, A 1995. Growth hormone signaling leading to CYP2C12 gene expression in rat hepatocytes involves phospholipase A2. J. Biol. Chem. 270(21): 12569-12577 https://doi.org/10.1074/jbc.270.21.12569
  24. Tsuji, K., Oshima, S., Tsuji-Matsusaki, E., Nakamura, A., Inami, T. and Suzuki, S. 1968. Effect of polysaccharides on cholesterol metabolism. Elyougaku Zasshi(in Japanese). 26: 113-122
  25. Tsuji, K., Tsuji, M. E. and Suzuki, S. 1977. Effect of polysaccharides on cholesterol metabolism. IV. Effects of various polysaccharide derivatives, lignin, and synthetic polymers on serum and liver cholesterol levels in rats. Elyougaku Zasshi(in Japanese). 35:227-234
  26. Wilks, D. L. 1998. Peak milk and its affect on profitability. http://www.moorman.com/feedfacts/ dairy/dairydec98/peakmilk.htm
  27. Wolf, M., Ingbar, S. H. and Moses, A C. 1989. Thyroidhormone and growthhormone interact to regulate insulin-like growth factor-I messenger ribonucleic acid and circulating levels in the rat. Endocrinology. 125:2905-2914 https://doi.org/10.1210/endo-125-6-2905
  28. Yamanloto, I., Takallashi, M., Suzuki, T., Seino, H. and Mori, H. 1984. Antitumor effect of seaweeds. IV. Enhancement of antitumor activity by sulfation of a crude fucoidan fraction from Sargassum kjellmanianum. Jpn. J. Exp. Med. 54(4):143-151
  29. Yonekura, L. and Suzuki, H. 2003. Some polysaccharides improve zinc bioavailability in rats fed a phytic acid-containing diet. Nutrition Research 23:343-355 https://doi.org/10.1016/S0271-5317(02)00538-9
  30. Zhuang, C., Itoh, H., Mizuno, T. and Ito, H. 1995. Antitwnor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii). Biosci Biotechnol. Biochem. 59(4):563-567 https://doi.org/10.1271/bbb.59.563
  31. 강종호. 2001. 양식 미역산업의 가격지지제도 개선을 위한 정책방향. 한국해양수산개발원. p. 11
  32. 경선이. 1991. 해조류(미역, 김)의 섭취가 흰쥐의 지질대사에 미치는 영향-동덕여자대학교 석사학위논문
  33. 김선희, 김우현, 김응국, 김인산, 김정희, 나도선, 박길홍, 백형환, 이기영 공역. 2002. 생화학(Lehninger Principles of biochemistry). 서울 외국서적. 서울
  34. 백인규, 맹원재, 이성훈, 이홍구, 이상락, 허종규,이성설, 황주환. 2004. 미역부산물 첨가가 In Vitro 발효성상과 젖소의 산유량 및 유성분에 미치는 영향. 한국동물자원과학회지. 46(3):373-386
  35. 이남호, 오기림. 2000. 해조류 라디칼 소거활성 검색. 제주생명과학연구. 3(3):95-100
  36. 최진호, 김대익, 박수현, 김동우, 백영호, 김창묵. 2000. 미역 (Undaria pinnatifida) 국수의 투여가 랫트 간장중의 활성산소 및 제거효소에 미치는 영향. 한국수산학회지. 33(2):87-92

Cited by

  1. Effect of Fermented Brown Seaweed Waste (FBSW) on in vitro Rumen Microbial Fermentation vol.53, pp.4, 2011, https://doi.org/10.5187/JAST.2011.53.4.349
  2. Effect of Feeding Seaweed as Mineral Source on Mineral Metabolism, Blood and Milk Mineral Profile in Cows vol.86, pp.1, 2016, https://doi.org/10.1007/s40011-014-0413-9
  3. Nutritional Evaluation of Seaweed on Nutrient Digestibility, Nitrogen Balance, Milk Production and Composition in Sahiwal Cows vol.87, pp.2, 2017, https://doi.org/10.1007/s40011-015-0616-8