• Title/Summary/Keyword: Information Poor

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A Study on the Level of Perception of the Health Condition of Koreans and Americans in Virginia, USA and Their Preference for Salty Taste (미국 버지니아주 거주 한국인과 미국인의 건강상태 인식도 및 짠맛 기호도 비교)

  • Kim, Mi-Ok
    • The Korean Journal of Food And Nutrition
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    • v.27 no.4
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    • pp.716-724
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    • 2014
  • This study was conducted as a comparative analysis, using the SPSS 17.0 program for a survey conducted from March to July 2013, on the level of perception and preference factors of Koreans and Americans residing in Virginia, USA(89 male and female adults of 20 years of age or above). For the information on the degree of obesity, a survey was used and the subjects provided with their heights and weights. The researcher used this data to calculated their BMI and distinguished the degrees of obesity. For the BMI, the obesity diagnosis of Korean Society for the Study of Obesity was used for Koreans, and the WHO's obesity diagnosis on adults were employed for Americans. First, regarding the Korean participants, the level of obesity appeared in the order of normal (79.6%), overweight (14.3%), and underweight (6.1%). Also, the level of perceptions of their health conditions appeared in the order of average (51.7%) and good (34.7%). No one perceived their health to be in poor condition. Meanwhile, for the American participants, the order was as follows: overweight at about 45%, normal weight at about 35%, obesity at about 12.5%, and underweight at about 7.5%. In terms of the level of perception of health during ordinary times, about 55% of the American participants answered that they are in good health. Therefore, the Americans were found to perceive their health to be in relatively better condition than the Koreans residing in the USA. Also, concerning the level of interest in health while eating food at ordinary times, the American participants were discovered to be more interested (about 62.5%) than the Korean participants. The research on their preference for salty taste was conducted as a survey, and the subjects were asked to choose an item according to their subjective feeling. Regarding the preference for salty taste, both Koreans and Americans residing in the USA responded as moderate. However, a higher proportion of Americans than Koreans responded to favor salty taste. Concerning the reason for their preference for salty taste, Koreans responded with various reasons whereas Americans mostly responded that it is because they eat salty food frequently. For any changes in dietary behavior related to eating salty food, both Korean and American respondents thought that the amount of their daily intake of salt is appropriate and that they consider taste as most important in selecting a snack. Based on the above data, the results of this research indicate a need for actual improvement in the diet with regard to salty food along with diverse policies for promoting life with a low salt diet in future.

Why a Combination of WP 631 and Epo B is an Improvement on the Drugs Singly - Involvement in the Cell Cycle and Mitotic Slippage

  • Bukowska, Barbara;Rogalska, Aneta;Forma, Ewa;Brys, Magdalena;Marczak, Agnieszka
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1299-1308
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    • 2016
  • Our previous studies clearly demonstrated that a combination of WP 631 and Epo B has higher activity against ovarian cancer cells than either of these compounds used separately. In order to fully understand the exact mechanism of action in combination, we assessed effects on the cell cycle of SKOV-3 cells. We evaluated three control points essential for WP 631 and Epo B action to determine which cell cycle-regulating proteins (CDK1/cyclin B complex, EpCAM or HMGB1) mediate activity. The effects of the drug on the cell cycle were measured based on the nuclear DNA content using flow cytometry. Expression of cell cycle-regulating genes was analyzed using real-time PCR. It was discovered that WP 631, at the tested concentration, did not affect the SKOV-3 cell cycle. Epo B caused significant G2/M arrest, whereas the drug combination induced stronger apoptosis and lower mitotic arrest than Epo B alone. This is very important information from the point of view of the fight against cancer, as, while mitotic arrest in Epo B-treated cells could be overcame after DNA damage repair, apoptosis which occurs after mitotic slippage in combination-treated cells is irreversible. It clearly explains the higher activity of the drug combination in comparison to Epo B alone. Epo B acts via the CDK1/cyclin B complex and has the ability to inhibit CDK1, which may be a promising strategy for ovarian cancer treatment in the future. The drug combination diminishes EpCAM and HMGB1 expression to a greater degree than either WP 631 and Epo B alone. Owing to the fact that the high expression of these two proteins is a poor prognostic factor for ovarian cancer, a decrease in their expression, observed in our studies, may result in improved efficacy of cancer therapy. The presented findings show that the combination of WP 631 and Epo B is a better therapeutic option than either of these drugs alone.

Feasibility Study of Case-Finding for Breast Cancer by Community Health Workers in Rural Bangladesh

  • Chowdhury, Touhidul Imran;Love, Richard Reed;Chowdhury, Mohammad Touhidul Imran;Artif, Abu Saeem;Ahsan, Hasib;Mamun, Anwarul;Khanam, Tahmina;Woods, James;Salim, Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7853-7857
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    • 2015
  • Background: Mortality from breast cancer is high in low- and middle-income countries, in part because most patients have advanced stage disease when first diagnosed. Case-finding may be one approach to changing this situation. Materials and Methods: We conducted a pilot study to explore the feasibility of population-based case finding for breast cancer by community health workers (CHWs) using different data collection methods and approaches to management of women found to have breast abnormalities. After training 8 CHWs in breast problem recognition, manual paper data collection and operation of a cell-phone software platform for reporting demographic, history and physical finding information, these CHWs visited 3150 women >age 18 and over they could find-- from 2356 households in 8 villages in rural Bangladesh. By 4 random assignments of villages, data were collected manually (Group 1), or with the cell-phone program alone (Group 2) or with management algorithms (Groups 3 and 4), and women adjudged to have a serious breast problem were shown a motivational video (Group 3), or navigated/accompanied to a breast problem center for evaluation (Group 4). Results: Only three visited women refused evaluation. The manual data acquisition group (1) had missing data in 80% of cases, and took an average of 5 minutes longer to acquire, versus no missing data in the cell phone-reporting groups (2,3 and 4). One woman was identified with stage III breast cancer, and was appropriately treated. Conclusions: Among very poor rural Bangladeshi women, there was very limited reluctance to undergo breast evaluation. The estimated rarity of clinical breast cancer is supported by these population-based findings. The feasibility and efficient use of mobile technology in this setting is supported. Successor studies may most appropriately be trials focusing on improving the suggested benefits of motivation and navigation, on increasing the numbers of cases found, and on stage of disease at diagnosis as the primary endpoint.

Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer

  • He, Wen-Zhuo;Jiang, Chang;Yin, Chen-Xi;Guo, Gui-Fang;Rong, Ru-Ming;Qiu, Hui-Juan;Chen, Xu-Xian;Zhang, Bei;Xia, Liang-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7327-7331
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    • 2014
  • Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), ${\gamma}$-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) patients. In this study we developed a prognostic model based on these three indices. Materials and Methods: A total of 243 patients who were initially diagnosed as mCRC between 2005 and 2010 in the Sun Yat-sen University Cancer Center were studied. The endpoint was overall survival (OS). Results: NLR>3, elevated GGT and elevated CEA were confirmed as independent risk factors which could predict poor prognosis. Patients could be divided into three groups according to the number of risk factors they had. Those with two or three were defined as the high risk group, individuals with one risk factor as the modest risk group and patients without risk factor as the low risk group. The OS values for these three groups were 16.2 months (2.80~68.8), 24.2 months (4.07~79.0), and 37.2 months (12.6~87.8), respectively (p<0.001). Conclusions: We developed a simple but useful model based on NLR, GGT and CEA to provide prognostic information to clinical practice in highly selected mCRC patients. Further prospective and multi-center studies are warranted to test our model.

Web Site Keyword Selection Method by Considering Semantic Similarity Based on Word2Vec (Word2Vec 기반의 의미적 유사도를 고려한 웹사이트 키워드 선택 기법)

  • Lee, Donghun;Kim, Kwanho
    • The Journal of Society for e-Business Studies
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    • v.23 no.2
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    • pp.83-96
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    • 2018
  • Extracting keywords representing documents is very important because it can be used for automated services such as document search, classification, recommendation system as well as quickly transmitting document information. However, when extracting keywords based on the frequency of words appearing in a web site documents and graph algorithms based on the co-occurrence of words, the problem of containing various words that are not related to the topic potentially in the web page structure, There is a difficulty in extracting the semantic keyword due to the limit of the performance of the Korean tokenizer. In this paper, we propose a method to select candidate keywords based on semantic similarity, and solve the problem that semantic keyword can not be extracted and the accuracy of Korean tokenizer analysis is poor. Finally, we use the technique of extracting final semantic keywords through filtering process to remove inconsistent keywords. Experimental results through real web pages of small business show that the performance of the proposed method is improved by 34.52% over the statistical similarity based keyword selection technique. Therefore, it is confirmed that the performance of extracting keywords from documents is improved by considering semantic similarity between words and removing inconsistent keywords.

SOCIOPSYCHIATRIC CHARACTERISTICS OF ELEMENTARY SCHOOL CHILDREN WHO USE COMPUTERS EXCESSIVELY - ON THE BASIS OF CARERS' REPORT - (컴퓨터 과다사용 초등학생의 정신사회적 특성 - 보호자의 보고를 근거로 -)

  • Jhin, Hea-Kyung;Kim, Mun-Sun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.14 no.2
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    • pp.229-237
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    • 2003
  • Objectives:Among the studies related to excessive computer use, the studies for elementary school students are relatively rare. Because children have relatively poor ability to recognize and express themselves, the carers' information is important to assess the children. This study attempted to investigate the relationship between children's computer use and sociopsychiatric characteristics on the basis of carers' reports. Methods:The subjects of this study were 287 5th- and 6th-grade students in the elementary school in Seoul. The student carers were asked to answer the questions for children's computer use, the computer addiction test modified from Young's parent-child internet addiction test, Korean Personality Inventory for Children(K-PIC). SPSS(version 10) was used to analyse the differnece of computer use between genders and the relation of the computer addiction test with K-PIC. Results:1) The score of computer addiction test was significantly higher in male children than in female children and more male children compared to female children were distributed in the excessive user group. 2) The score of computer addiction test correlated with the scores of most clinical scales of K-PIC and the average scores of most clinical scale were significantly higher in the excessive user group than in the general user group. 3) More children with score above 65 in HPR, DLQ, FAM scale were distributed in excessive user group than in general user group. Conclusion:The 5th- and 6th-grade elementary school students with excessive computer use were found to show more sociopsychiatric problems. With these finding we suggest that social and clinical attention to the children who use computer excessively shoud be required.

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The Comparative Analysis Study and Usability Assessment of Fat Suppressed 3D FSPGR T1 Technique and Fat Suppressed Isotropic 3D FSE T1 Technique when Examining MRI of Patient with Triangular Fibrocartilage Complex (TFCC) Tear (삼각 섬유성 연골(TFCC) 손상 환자의 자기공명영상 검사 시 Fat Suppressed 3D FSPGR T1 강조 기법에 대한 Fat Suppressed Isotropic 3D FSE T1 강조 기법의 비교 분석 및 유용성에 관한 평가)

  • Kang, Sung-Jin;Cho, Yong-Keun;Lee, Sung-Soo
    • Journal of the Korean Magnetics Society
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    • v.26 no.3
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    • pp.105-114
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    • 2016
  • In this study, For assessment of triangular fibrocartilage complex (TFCC) injury, we acquired images by fat suppressed 3D fast spoiled gradient recalled T1 and fat suppressed Isotropic 3D fast spin echo T1 techniques. For quantitative evaluation, measured signal to noise ratio and contrast to noise ratio and verified statistical significance between two imaging techniques by Mann-Whitney U verification. And for qualitative evaluation, marked 4-grade scoring (0: non diagnostic, 1: poor, 2: adequate, 3: good) on shape of TFCC, artifacts by partial volumes, description of the lesions by two radiologist, verified coincidence between 2 observer using Kappa-value verification. We used 3.0 Tesla MR equipment and 8-channel RF coil for imaging acquisition. As quantitative evaluation results, signal to noise ratio and contrast to noise ratio value of Isotropic 3D fast spin echo T1 technique is higher in every image sections, also between two imaging techniques by Mann-Whitney U verification was statistically significant (p < 0.05). As qualitative results, observer 1, 2 marked a higher grade on Isotropic 3D FSE T1 technique, coincidence verification of evaluation results between two observers by Kappa-value verification was statistically significant (p < 0.05). As a result, during MRI examination on TFCC injury, fat suppressed Isotropic 3D fast spin echo T1 technique is considered offering more useful information about abnormal lesion of TFCC.

An Improvement of Interoperability for HD-Class VOD Content Management System Based on H.264 (H.264 기반 HD급 VOD 콘텐츠관리시스템 상호운용성 개선)

  • Min, Byung-Won
    • Journal of Digital Convergence
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    • v.12 no.2
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    • pp.315-320
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    • 2014
  • Recently, although the requirement of quality of VOD content has been transferred upto the class of HD, conventional management systems characterized by OS dependency are truly limited in quality of video image, stability, and compatibility of network environments. In addition most of the content management systems realize very limited capabilities for the real affairs of content management and distribution services in such an OS dependent environment. In this paper, we propose a new scheme of HD-Class VOD Content Management System to solve these problems. We design and implement the proposed system based on open sources by using H.264 video compression method. The proposed system offers high quality content management method based on opened systems and independent on-line distribution method so that it can be realized as an integrated management scheme for VOD contents. Moreover, our system solves the problems of occasional cutting-down video, small screen, and poor image quality that exist in the conventional wmv-type CMS. According to the result of performance evaluation, our system maintains sufficient performance and tolerence for the case of large scale HD content operations or fabrications. We expect that the proposed integrated DB scheme will especially be effective when the content management applications are changed from Internet Web environments to mobile terminal environments.

Analysis of China's Arctic Route Development associated with the Belt and Road initiative (중국의 북극항로 개발사업, 일도(一道)의 특징과 시사점)

  • Song, Min-Geun
    • Journal of Digital Convergence
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    • v.16 no.2
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    • pp.103-115
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    • 2018
  • The potential competitiveness for new routes and resources has been theoretically discussed with regards to the Arctic route but is gradually becoming a reality as global warming increases. In June of 2017, China officially included the Northern Sea Route (NSR) as part of the Belt and Road Initiative (BRI), and major countries' interests in the NSR are greatly expanding. This paper presents the general characteristics of the NSR, NSR development in China, the expected relationship between the NSR and the BRI, and this relationship's implications for Korea. The NSR has poor facilities and information infrastructure and is not economically viable for commercial navigation due to its high-cost conditions compared to competitive routes. In order to explore the Arctic and develop the NSR, large-scale projects must be funded over a long period of time; this has caused major difficulties in development. However, as the NSR is included in the BRI, there could be an opportunity to utilize BRI funds, such as Asian Infrastructure Investment Bank (AIIB). Further, China's NSR development and the NSR development of partner countries, such as Korea, should be further stimulated. As Korea has strengths in terms of its shipbuilding technology and geographical location, which is located at the core of the NSR, Korea would have chances to expand the economic cooperation and business opportunities with China and Russia.

Optimal Growth Model of the Cochlodinium Polykrikoides (Cochlodinium Polykrikoides 최적 성장모형)

  • Cho, Hong-Yeon;Cho, Beom Jun
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.26 no.4
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    • pp.217-224
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    • 2014
  • Cochlodinium polykrikoides is a typical harmful algal species which generates the red-tide in the coastal zone, southern Korea. Accurate algal growth model can be established and then the prediction of the red-tide occurrence using this model is possible if the information on the optimal growth model parameters are available because it is directly related between the red-tide occurrence and the rapid algal bloom. However, the limitation factors on the algal growth, such as light intensity, water temperature, salinity, and nutrient concentrations, are so diverse and also the limitation function types are diverse. Thus, the study on the algal growth model development using the available laboratory data set on the growth rate change due to the limitation factors are relatively very poor in the perspective of the model. In this study, the growth model on the C. polykrikoides are developed and suggested as the optimal model which can be used as the element model in the red-tide or ecological models. The optimal parameter estimation and an error analysis are carried out using the available previous research results and data sets. This model can be used for the difference analysis between the lab. condition and in-situ state because it is an optimal model for the lab. condition. The parameter values and ranges also can be used for the model calibration and validation using the in-situ monitoring environmental and algal bloom data sets.