• Title/Summary/Keyword: Information Amplification

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Improvement of early prediction performance of under-performing students using anomaly data (이상 데이터를 활용한 성과부진학생의 조기예측성능 향상)

  • Hwang, Chul-Hyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.11
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    • pp.1608-1614
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    • 2022
  • As competition between universities intensifies due to the recent decrease in the number of students, it is recognized as an essential task of universities to predict students who are underperforming at an early stage and to make various efforts to prevent dropouts. For this, a high-performance model that accurately predicts student performance is essential. This paper proposes a method to improve prediction performance by removing or amplifying abnormal data in a classification prediction model for identifying underperforming students. Existing anomaly data processing methods have mainly focused on deleting or ignoring data, but this paper presents a criterion to distinguish noise from change indicators, and contributes to improving the performance of predictive models by deleting or amplifying data. In an experiment using open learning performance data for verification of the proposed method, we found a number of cases in which the proposed method can improve classification performance compared to the existing method.

Molecular identification of fruit bats, natural host of Nipah virus in Bangladesh, based on DNA barcode

  • Md. Maharub Hossain Fahim;Walid Hassan;Afia Afsin;Md. Mahfuzur Rahman;Md. Tanvir Rahman;Sang Jin Lim;Yeonsu Oh;Yung Chul Park;Hossain Md. Faruquee;Md. Mafizur Rahman
    • Journal of Ecology and Environment
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    • v.48 no.2
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    • pp.163-172
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    • 2024
  • Background: Fruit bats are natural carriers of Nipah virus (NiV). The primary objective of this study is to identify potential reservoir species in a selected geographic regions. It is necessary to determine an accurate species identification of the associated reservoir bat species distributed in a specific region. Results: In this study, we collected 20 different bat specimens from the NiV-prone area of the Kushtia district. Among these, 14 were tissue samples (BT-1-14) and six were fecal samples (BF-1-6). We used the mitochondrial gene cytochrome b, one of the most abundant and frequently used genetic markers, for polymerase chain reaction amplification and sequencing. Out of the 20 samples, 12 tissue samples and 2 fecal samples were successfully amplified and sequenced. However, two tissue samples and four fecal samples yielded chimeric sequences, rendering them unsuitable for annotation. The sequences of the successfully amplified samples were compared to those deposited in the National Center for Biotechnology Information database using basic local alignment search tool to identify the bat specimen collected. The study identified six different bat species using both morphological and genetic data, which may carriers of the NiV. Conclusions: Our results suggest that additional research should be conducted to gather more information on fruit bats from different localities across the country. The study contributes to the establishment of appropriate measures for NiV carrying disease control and management.

Prediction of Genomic Relationship Matrices using Single Nucleotide Polymorphisms in Hanwoo (한우의 유전체 표지인자 활용 개체 혈연관계 추정)

  • Lee, Deuk-Hwan;Cho, Chung-Il;Kim, Nae-Soo
    • Journal of Animal Science and Technology
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    • v.52 no.5
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    • pp.357-366
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    • 2010
  • The emergence of next-generation sequencing technologies has lead to application of new computational and statistical methodologies that allow incorporating genetic information from entire genomes of many individuals composing the population. For example, using single-nucleotide polymorphisms (SNP) obtained from whole genome amplification platforms such as the Ilummina BovineSNP50 chip, many researchers are actively engaged in the genetic evaluation of cattle livestock using whole genome relationship analyses. In this study, we estimated the genomic relationship matrix (GRM) and compared it with one computed using a pedigree relationship matrix (PRM) using a population of Hanwoo. This project is a preliminary study that will eventually include future work on genomic selection and prediction. Data used in this study were obtained from 187 blood samples consisting of the progeny of 20 young bulls collected after parentage testing from the Hanwoo improvement center, National Agriculture Cooperative Federation as well as 103 blood samples from the progeny of 12 proven bulls collected from farms around the Kyong-buk area in South Korea. The data set was divided into two cases for analysis. In the first case missing genotypes were included. In the second case missing genotypes were excluded. The effect of missing genotypes on the accuracy of genomic relationship estimation was investigated. Estimation of relationships using genomic information was also carried out chromosome by chromosome for whole genomic SNP markers based on the regression method using allele frequencies across loci. The average correlation coefficient and standard deviation between relationships using pedigree information and chromosomal genomic information using data which was verified using a parentage test andeliminated missing genotypes was $0.81{\pm}0.04$ and their correlation coefficient when using whole genomic information was 0.98, which was higher. Variation in relationships between non-inbred half sibs was $0.22{\pm}0.17$ on chromosomal and $0.22{\pm}0.04$ on whole genomic SNP markers. The variations were larger and unusual values were observed when non-parentage test data were included. So, relationship matrix by genomic information can be useful for genetic evaluation of animal breeding.

A 2.0-GS/s 5-b Current Mode ADC-Based Receiver with Embedded Channel Equalizer (채널 등화기를 내장한 2.0GS/s 5비트 전류 모드 ADC 기반 수신기)

  • Moon, Jong-Ho;Jung, Woo-Chul;Kim, Jin-Tae;Kwon, Kee-Won;Jun, Young-Hyun;Chun, Jung-Hoon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.12
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    • pp.184-193
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    • 2012
  • In this paper, a 5-bit 2-GS/s 2-way time interleaved pipeline ADC for high-speed serial link receiver is demonstrated. Implemented as a current-mode amplifier, the stage ADC simultaneously processes the tracking and residue amplification to achieve higher sampling rate. In addition, each stage incorporates a built-in 1-tap FIR equalizer, reducing inter-symbol-interference (ISI)without an extra digital post-processing. The ADC is designed in a 110nm CMOS technology. It comsumes 91mW from a 1.2-V supply. The area excluding the memory block is $0.58{\times}0.42mm^2$. Simulation results show that when equalizer is enabled, the ADC achieves SNDR of 25.2dB and ENOB of 3.9bits at 2.0GS/s sample rate for a Nyquist input signal. When the equalizer is disengaged, SNDR is 26.0dB for 20MHz-1.0GHz input signal, and the ENOB of 4.0bits.

Assessment of Seismic Site Response at Hongseong in Korea Based on Two-dimensional Basin Modeling using Spatial Geotechnical Information (공간 지반 정보를 활용한 이차원 분지 모델링 기반의 국내 홍성 지역에서의 부지 지진 응답 평가)

  • Sun, Chang-Guk
    • The Journal of Engineering Geology
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    • v.19 no.1
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    • pp.15-23
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    • 2009
  • The site effects relating to the amplification of ground motion under earthquake loading are strongly influenced by both the subsurface soil condition and geologic structure. In this study, the site effects at the Hongseong area in Korea were examined by both the site investigation including borehole drilling and in-situ seismic tests and the site visit for acquiring geologic information of ground surface. Subsurface of Hongseong area with a major instrumental earthquake event in 1978 is composed of weathered layers of a maximum of 45 m thickness overlying bedrock. A geotechnical information system based on GIS framework was implemented to effectively find out spatial geologic structure of study area and it indicated Hongseong is a shallow and wide shaped basin. Two-dimensional finite element (FE) analyses for a representative cross-section of the Hongseong area were performed to evaluate seismic site responses. From the results of seismic responses, it was observed that the ground motions were amplified during the propagation of shear waves through the soil layer overlying the bedrock and the duration of shaking near the basin edges was prolonged due to the surface waves generated by interactions of shear waves with basin geometry. Furthermore, one-dimensional FE seismic response analyses were additionally conducted for soil sites selected in the basin, and it gives similar results to the two-dimensional seismic responses at most locations in the basin with the exception of the locations near the basin edges, because the basin in this study is very shallow and wide.

Site Classification for Incheon According to Site-Specific Seismic Response Parameters by Estimating Geotechnical Spatial Information Based on GIS (GIS 기반 지반공간정보 추정을 통한 부지고유 지진응답 매개변수 기반 인천 지역의 부지분류)

  • SUN, Chang-Guk;KIM, Han-Saem
    • Journal of the Korean Association of Geographic Information Studies
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    • v.19 no.4
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    • pp.17-35
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    • 2016
  • Earthquake-induced disasters are often more severe in locations with soft soils than firm soils or rocks due to differences in ground motion amplification. On a regional scale, such differences can be estimated by spatially predicting subsurface soil thickness over the entire target area. In general, soil deposits are generally deeper in coastal or riverside areas than in inland regions. In this study, a coastal metropolitan area, Incheon, was selected to assess site effects and provide information on seismic hazards. Spatial prediction of geotechnical layers was performed for the entire study area within the GIS framework. Approximately 7,000 existing borehole drilling data in the Incheon area were gathered and archived into the GIS Database (DB). In addition, surface geotechnical data were acquired from a walkover survey. Based on the built geotechnical DB, spatial zoning maps of site-specific seismic response parameters were created and presented for use in a regional seismic strategy. Site response parameters were performed to determine site coefficients for seismic design over the entire target area and compared with each other. Site classifications and subsequent seismic zoning were assigned based on site coefficients. From this seismic zonation case study in Incheon, we verified that geotechnical GIS-DB can create spatial zoning maps of site-specific seismic response parameters that are useful for seismic hazard mitigation particularly in coastal metropolitan areas.

Identification of Marker Nucleotides for the Molecular Authentication of Arisaematis Rhizoma Based on the DNA Barcode Sequences (천남성(天南星) 유전자 감별을 위한 DNA 바코드 분석 및 Marker Nucleotide 발굴)

  • Kim, Wook Jin;Lee, Young Mi;Ji, Yunui;Kang, Young Min;Choi, Goya;Kim, Ho Kyoung;Moon, Byeong Cheol
    • The Korea Journal of Herbology
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    • v.29 no.6
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    • pp.35-43
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    • 2014
  • Objectives : Official Arisaematis Rhizoma is described only three species, Arisaema amurnse, Arisaema erubescens, and Arisaema heterophyllum, in national Pharmacopoeia. However, other Arisaema species, Arisaema ringens, Arisaema takesimense and Arisaema serratum, also have been distributed as an inauthentic Arisaematis Rhizoma in the herbal market. To develop a reliable molecular authentication method for Arisaematis Rhizoma in species level, we analyzed DNA barcode regions using six Arisaema species. Methods : Thirty-eight samples of six Arisaema plants species (A. amurense, A. amurense f. serratum, A. heterophyllum, A. takesimense, and A. serratum) were collected from different habitate and nucleotide sequences of DNA barcode regions (rDNA-ITS, matK, and rbcL gene) were analyzed after PCR amplification. The species-specific sequences and phylogenetic relations were estimated using entire sequences of three DNA barcodes based on the analysis of ClastalW and UPGMA, respectively. Results : The comparative analysis of DNA barcode sequences were revealed inter-species specific nucleotides to distinguish the medicinal plant of Arisaema Rhizoma in species levels excluding between A. amurense and its subspecies (A. amurense f. serratum) and A. takesimense and A. serratum, respectively. However, we obtained sequence differences enough to discriminate authentic and inauthentic Arisaematis Rhizoma. Therefore, we suggest that these SNP type molecular genetic markers were an reliable method avaliable to identify official herbal medicines. Conclusions : These marker nucleotides could be useful to identify the official herbal medicines by providing definitive information that can identify original medicinal plant and distinguish from inauthentic adulterants and substitutes.

Identification of specific SNP molecular marker from Cudrania tricuspidata using DNA sequences of chloroplast TrnL-F region (구지뽕 나무의 엽록체 TrnL-F 영역 염기서열 분석을 통한 특이적 SNP 분자마커의 확인)

  • Lee, Soo Jin;Shin, Yong-Wook;Kim, Yun-Hee;Lee, Shin-Woo
    • Journal of Plant Biotechnology
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    • v.44 no.2
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    • pp.135-141
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    • 2017
  • Cudrania tricuspidata Bureau is a widely used medicinal perennial woody plant. For conservation and germplasm utilization of the plant, it is imperative to obtaining information regarding the genetic diversity of the plant populations. Although C. tricuspidata is an important medicinal plant registered in South Korea, no molecular markers are currently available to distinguish Korean-specific ecotypes from other ecotypes of different countries. In this study, we developed single nucleotide polymorphism (SNP) markers derived from chloroplast genomic sequences to identify distinct Korean-specific ecotypes of C. tricuspidata via the amplification refractory mutation system (ARMS)-PCR analyses. Molecular authentication of twelve C. tricuspidata ecotypes from different regions was performed, using DNA sequences in the trnL-F chloroplast intergenic region. The SNP markers developed in this study are useful for rapidly identifying specific C. tricuspidata ecotypes from different regions.

Core Circuit Technologies for PN-Diode-Cell PRAM

  • Kang, Hee-Bok;Hong, Suk-Kyoung;Hong, Sung-Joo;Sung, Man-Young;Choi, Bok-Gil;Chung, Jin-Yong
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.8 no.2
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    • pp.128-133
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    • 2008
  • Phase-change random access memory (PRAM) chip cell phase of amorphous state is rapidly changed to crystal state above 160 Celsius degree within several seconds during Infrared (IR) reflow. Thus, on-board programming method is considered for PRAM chip programming. We demonstrated the functional 512Mb PRAM with 90nm technology using several novel core circuits, such as metal-2 line based global row decoding scheme, PN-diode cells based BL discharge (BLDIS) scheme, and PMOS switch based column decoding scheme. The reverse-state standby current of each PRAM cell is near 10 pA range. The total leak current of 512Mb PRAM chip in standby mode on discharging state can be more than 5 mA. Thus in the proposed BLDIS control, all bitlines (BLs) are in floating state in standby mode, then in active mode, the activated BLs are discharged to low level in the early timing of the active period by the short pulse BLDIS control timing operation. In the conventional sense amplifier, the simultaneous switching activation timing operation invokes the large coupling noise between the VSAREF node and the inner amplification nodes of the sense amplifiers. The coupling noise at VSAREF degrades the sensing voltage margin of the conventional sense amplifier. The merit of the proposed sense amplifier is almost removing the coupling noise at VSAREF from sharing with other sense amplifiers.

Analysis of Microsatellite Markers for Forensic Identification in cats (고양이의 개체식별을 위한 microsatellite marker 분석)

  • Cho Gil-Jae
    • Journal of Life Science
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    • v.16 no.3 s.76
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    • pp.382-386
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    • 2006
  • A total number of 20 cat samples including 8 parentage testing and 12 individual identification were genotyped. Genomic DNA was extracted from buccal swab, and genotyped by using 10 microsatellite markers (FCA005, FCA26, FCA224, FCA240, FCA453, FCA293, FCA075, FCA105, FCA229, and FCA651). This method consisted of single PCR procedure and showed reasonable amplification of all PCR products. Genotypes were determined by genetic analyzer. The number of alleles per locus of cats varied from 3 to 8 with a mean value of 5.5. Expected heterozygosity was ranged from 0.390 to 0.827 (mean 0.639) and the total exclusion probability of 10 microsatellite loci was 0.9441. Of the 10 markers, FCA240 marker has relatively high PIC value (>0.7). Of the 8 cats, 7 cats were qualified by compatibility according to the Mendelism. These results can give basic information for developing parentage verification and individual identification system in cat.