• Clinics in Shoulder and Elbow
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• v.21 no.2
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• pp.87-94
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• 2018

Background: Popeye deformity is common after rupture of the biceps muscle's long head tendon. Herein, we report on histological changes in biceps brachii muscles following tenotomy of the long head biceps tendon. Methods: Twelve Sprague-Dawley rats (12-week-old) underwent tenotomy of the long head biceps tendon in the right shoulder. At postoperative weeks 4, 7, and 10, the operative shoulders were removed by detaching the biceps brachii muscle from the glenoid scapula and humerus; the opposite shoulders were removed as controls. H&E staining was performed to elucidate histological changes in myocytes. Oil-red O staining was performed to determine fatty infiltration. Myostatin antibody immunohistochemistry staining was performed as myostatin is expressed by skeletal muscle cells during myogenesis. Results: H&E staining results revealed no changes in muscle cell nuclei. There were no adipocytes detected. Compared with that of the control biceps, the cross-sectional area of the long head biceps was significantly smaller (p=0.00). Statistical changes in the total extent of the 100 muscle cells were significant (p=0.00). Oil-red O staining revealed no fatty infiltration. Myostatin antibody immunohistochemical staining revealed no significant difference between the two sides. Conclusions: Muscular changes after tenotomy of the long head biceps included a decrease in the size of the individual muscle cells and in relative muscle mass. There were no changes observed in muscle cell nuclei and no fatty infiltration. Moreover, there were no changes detected by myostatin antibody immunohistochemistry assay.

• Journal of Korean Society on Water Environment
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• v.34 no.1
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• pp.57-66
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• 2018

Water disasters such as flash floods and inundation caused by localized heavy rainfall in urban areas have a large impact on climate change but are also closely related to the increase in impervious areas as pointed out in domestic and international studies. It is difficult to secure natural green areas in urban areas that have already been developed. So, urban regeneration can be expected using water management optimized with technologies to secure infiltration and storage capacity such as Low-Impact Development technology. In this study, the water cycle improvement ability was confirmed by applying the LID technology within the district unit plan of the environmentally friendly village, and the economic feasibility of LID application was analyzed by estimating the costs and benefits of installing the facilities. The site was planned to conserve sufficient green and plans for securing the watershed infiltration and storage capacity were formulated with the application of additional LID technology, such as infiltration trenches, rain barrels and permeable pavements. The LID design method applicable to the site was established, and the water balance of the watershed was analyzed through simulations of the SWMM model. The water circulation improvement effect was confirmed through the water balance analysis, and the cost-benefits were determined according to the estimation method, and the economic analysis was conducted. This study confirms that the investment of LID technology is economically feasible for the hydrological improvement effect of the housing complex.

• Nutrition Research and Practice
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• v.10 no.5
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• pp.494-500
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• 2016

BACKGROUND/OBJECTIVES: Evidence indicates that berry anthocyanins are anti-atherogenic, antioxidant, and anti-inflammatory. However, berries differ vastly in their anthocyanin composition and thus potentially in their biological and metabolic effects. The present study compared hypolipidemic, antioxidant, and anti-inflammatory properties of blueberry (BB), blackberry (BK), and blackcurrant (BC) in a diet-induced obesity (DIO) mouse model. MATERIALS/METHODS: Male C57BL/6J mice were fed a high fat (HF; 35% fat, w/w) control diet or a HF diet supplemented with freeze-dried 5% BB, 6.3% BK or 5.7% BC for 12 weeks (10 mice/group) to achieve the same total anthocyanin content in each diet. Plasma lipids, antioxidant status and pro-inflammatory cytokines were measured. The expression of genes involved in antioxidant defense, inflammation, and lipid metabolism was determined in the liver, epididymal adipose tissue, proximal intestine, and skeletal muscle. Histological analysis was performed to identify crown-like structure (CLS) in epididymal fat pads to determine macrophage infiltration. RESULTS: No differences were noted between the control and any berry-fed groups in plasma levels of liver enzymes, insulin, glucose, ferric reducing antioxidant power, superoxide dismutase, and tumor necrosis factor ${\alpha}$. However, BK significantly lowered plasma triglyceride compared with the HF control and other berries, whereas BC significantly reduced F4/80 mRNA and the number of CLS in the epididymal fat pad, indicative of less macrophage infiltration. CONCLUSIONS: The present study provides evidence that BB, BK and BC with varying anthocyanin composition differentially affect plasma lipids and adipose macrophage infiltration in DIO mice, but with no differences in their antioxidant capacity and anti-inflammatory potential.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.557-562
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• 2002

The present study was made with the aim of finding out the Kamihaepyoijin-tang's effect on the allergic asthma using the Egg-White Implant(EWI) method model recommended by de Siqueira et al. Kamihaepyoijin-tang has widely been prescribed and used in Oriental Medicine for controlling and curing of cough, asthma, nasal obstruction. Previous studies have demonstrated that Kamihaepyoijin-tang had analgesic, anticonvulsive effects. But it is uncertain whether Kamihaepyoijin-tang could inhibit the allergic reaction of rats with experimentally induced allergic asthma using EWI method. With such aim. the respiratory patterns and eosinophil infiltration in the tracheal mucosa of the rats were mainly observed. The results were summerized as follows ; 1. The frequency of malformed respiratory patterns in Kamihaepyoijin-tang treated groups were decreased as compared with the control group. 2. The Ratio of malformed respiratory patterns in Kamihaepyoijin-tang treated groups were significantly decreased as compared with the control group(p<0.02). 3. The eosinophil infiltration in Kamihaepyoijin-tang treated groups were decreased as compared with the control group. 4. The eosinophil infiltration that inside of trachea tissue in Kamihaepyoijin-tang treated groups were significantly decreased as compared with the control group(p<0.05). Depending upon above results, it is considered that Kamihaepyoijin-tang has the inhibitory effects on the allergic asthma of rats and suggested that it could be used in relieving patients of the symptoms which are caused by allergic asthma.

• Journal of Korea Water Resources Association
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• v.51 no.4
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• pp.293-299
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• 2018

In this study, a new technique for evaluating the flood vulnerability of river banks is proposed. For this purpose, flood quantities of the basin were estimated based on the future climate change scenarios and the infiltration stability was evaluated by analyzing the infiltration behavior using SEEP/W which is a 2D groundwater infiltration model of the levee. The size of the river levee was investigated. The size of river levee was investigated by selecting the target area. The safety factor of the levee was analyzed considering the current flood level of the levee and the flood level considering the climate change. The factor needed to analyze the levee vulnerability was derived. We analyzed the vulnerability of the levee considering the change of the levee level according to the climate change scenarios. Levee Flood Vulnerability Index (LFVI) were used to evaluate the vulnerability of the levee.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.3C
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• pp.113-120
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• 2012

An actual slope failure was analyzed in residual soils at Jinju. Due to rainfall infiltration, the safety factor decreases in the unsaturated layers, since the effective stress and shear strength decrease. In this study, the effective stress is based on suction stress using soil water retention curve. Unsaturated properties were evaluated on soil water retention curve, hydraulic conductivity and shear strength with samples from the site. After infiltration analysis of unsaturated flow under the actual rainfall, the distribution of pore water pressure could be calculated in the slope layers. In the stress field of finite elements, an elastic analysis calculated total stress distribution in the layers and also shear stresses on the slip surface using elastic model. On the slip surface, suction stress and effective stress evaluated the shear strength. As a result, the factor of safety was calculated due to rainfall, which could simulate the actual slope failure. In particular, it was found that the suction stress increases and both the effective stress and the shear strength decrease simultaneously on the slip surface.

• Journal of Korean Society of Forest Science
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• v.112 no.4
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• pp.490-501
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• 2023

Laboratory column tests were conducted to analyze infiltration and water redistribution processes on the basis of rainfall. To efficiently measure moisture content within soil layers, this research developed a predictive model grounded in a convolutional neural network (CNN), a deep learning technique. The digital images obtained during the column tests were incorporated into the established CNN. The moisture content of each soil layer over time was effectively measured. The measured values were also in relatively good agreement with the moisture content determined using the moisture sensors installed for each soil layer. The use of CNN enabled a comprehensive understanding of continuous moisture distribution within the soil layers, as well as the infiltration process according to soil texture and initial moisture content conditions.

• Journal of the Korean Society of Hazard Mitigation
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• v.8 no.6
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• pp.7-14
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• 2008

The main objective of sewer rehabilitation is to improve its function while eliminating inflow/infiltration (I/I). If we can identify the amount of I/I for an individual pipe, it is possible to estimate the I/Is of sub-areas clearly. However, in real, the amount of I/I for an individual pipe is almost impossible to be obtained due to the limitation of cost and time. In this study, I/I occurrence of each sewer pipe is estimated using AHP (Analytic Hierarch Process) and RPDM (Rehabilitation Priority Decision Model for sewer system) was developed using the estimated I/I of each pipe to perform the efficient sewer rehabilitation. Based on the determined amount of I/I for an individual pipe, the RPDM determines the optimal rehabilitation priority (ORP) using a genetic algorithm for sub-areas in term of minimizing the amount of I/I occurring while the rehabilitation process is performed. The benefit obtained by implementing the ORP for rehabilitation of sub-areas is estimated by the only waste water treatment cost (WWTC) of I/I which occurs during the sewer rehabilitation period. The results of the ORP were compared with those of a numerical weighting method (NWM) which is the decision method for the rehabilitation priority in the general sewer rehabilitation practices and the worst order which are other methods to determine the rehabilitation order of sub-areas in field. The ORP reduced the WWTC by 22% compared to the NWM and by 40% compared to the worst order.

• Clinical and Experimental Pediatrics
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• v.56 no.11
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• pp.482-489
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• 2013

Purpose: The aim of the present study was to investigate the differences in lower airway inflammatory immune responses, including cellular responses and responses in terms of inflammatory mediators in bronchoalveolar lavage fluid (BALF) and the airway, to rhinovirus (RV) infection on asthma exacerbation by comparing a control and a murine asthma model, with or without RV infection. Methods: BALB/c mice were intraperitoneally injected with a crude extract of Dermatophagoides farinae (Df ) or phosphate buffered saline (PBS) and were subsequently intranasally treated with a crude extract of Df or PBS. Airway responsiveness and cell infiltration, differential cell counts in BALF, and cytokine and chemokine concentrations in BALF were measured 24 hours after intranasal RV1B infection. Results: RV infection increased the enhanced pause (Penh) in both the Df sensitized and challenged mice (Df mice) and PBS-treated mice (PBS mice) (P<0.05). Airway eosinophil infiltration increased in Df mice after RV infection (P<0.05). The levels of interleukin (IL) 13, tumor necrosis factor alpha, and regulated on activation, normal T cells expressed and secreted (RANTES) increased in response to RV infection in Df mice, but not in PBS mice (P<0.05). The level of IL-10 significantly decreased following RV infection in Df mice (P<0.05). Conclusion: Our findings suggest that the augmented induction of proinflammatory cytokines, Th2 cytokines, and chemokines that mediate an eosinophil response and the decreased induction of regulatory cytokines after RV infection may be important manifestations leading to airway inflammation with eosinophil infiltration and changes in airway responsiveness in the asthma model.

• Journal of Korea Water Resources Association
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• v.37 no.3
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• pp.195-206
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• 2004

One of the main factors which reduces the efficiency of a sewage treatment plant is the Inflow/Infiltration(Ⅰ/Ⅰ) in the sewer First we must calculate the quantity of Ⅰ/Ⅰ via the investigation of each sewer to establish the reduction plan of Ⅰ/Ⅰ. However, in Korea, we apply the results of a surveyed sample to the entire study area to establish the reduction plan of Ⅰ/Ⅰ. This methodology just considers the total Ⅰ/Ⅰ for the entire study area but it does not consider the quantity of Ⅰ/Ⅰ for the individual sewer systems. Therefore, we may need the model to consider the Ⅰ/Ⅰ in the individual sewer systems and we develop the model to calculate the Ⅰ/Ⅰ that happen in urban sewer systems. We estimate the Ⅰ/Ⅰ of individual systems by the developed model and the estimated Ⅰ/Ⅰ are utilized as the basic data for the establishment of Ⅰ/Ⅰ reduction plan. The observed Ⅰ/Ⅰ for the entire study area is distributed into the individual sewer systems according to their defect states. Here, the weights of defect elements are calculated using AHP(Analytic Hierarchy Process) and we perform the uncertainty analysis for considering the errors using MCS(Monte Carlo Simulation).