• 동서간호학연구지
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• 제28권1호
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• pp.21-30
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• 2022

Purpose: This research aimed to assess nursing students' knowledge, attitudes and infection prevention behaviors toward the coronavirus disease-19 (COVID-19). Methods: A cross-sectional survey was conducted from September 11 through October 1, 2020, involving a total of 235 third and fourth year of nursing students enrolled in two universities in U and K city. Self-report questionnaires consisting of demographic characteristics, knowledge, attitudes and infection prevention behaviors toward the COVID-19 were administered to the participants. Results: Influencing factors for infection prevention behaviors were gender (β=0.21, p<.001), attitudes toward infection control (β=0.38, p<.001), education experience regarding COVID-19 (β=0.21, p=.004), and a visit to the hospitals or the areas where the COVID-19 case has occurred or been admitted (β=-0.18, p=.003) which explained 23.6% of the total variance. Conclusion: The results of this study provides basic information regarding nursing students' knowledge about COVID-19, attitudes toward infection control, and infection prevention behaviors during the initial outbreak of COVID-19.

• Hip & pelvis
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• 제36권3호
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• pp.161-167
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• 2024

Periprosthetic joint infection (PJI) is regarded as a critical factor contributing to the failure of primary and revision total joint arthroplasty (TJA). With the increasing prevalence of TJA, a significant increase in the incidence of PJI is expected. The escalating number of cases, along with the significant economic strain imposed on healthcare systems, place emphasis on the pressing need for development of effective strategies for prevention. PJI not only affects patient outcomes but also increases mortality rates, thus its prevention is a matter of vital importance. The longer-term survival rates for PJI after total hip and knee arthroplasty correspond with or are lower than those for prevalent cancers in older adults while exceeding those for other types of cancers. Because of the multifaceted nature of infection risk, a collaborative effort among healthcare professionals is essential to implementing diverse strategies for prevention. Rigorous validation of the efficacy of emerging novel preventive techniques will be required. The combined application of these strategies can minimize the risk of infection, thus their comprehensive adoption is important. Collectively, the risk of PJI could be substantially minimized by application of a multifaceted approach implementing these strategies, leading to improvement of patient outcomes and a reduced economic burden.

• 대한간호학회지
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• 제50권5호
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• pp.658-670
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• 2020

Purpose: This study aimed to identify the predictors of blood and body fluid exposure (BBFE) in multifaceted individual (sleep disturbance and fatigue), occupational (occupational stress), and organizational (hospital safety climate) factors, as well as infection prevention behavior. We also aimed to test the mediating effect of infection prevention behavior in relation to multifaceted factors and the frequency of BBFE. Methods: This study was based on a secondary data analysis, using data of 246 nurses from the Shift Work Nurses' Health and Turnover study. Based on the characteristics of zero-inflated and over-dispersed count data of frequencies of BBFE, the data were analyzed to calculate zero-inflated negative binomial regression within a generalized linear model and to test the mediating effect using SPSS 25.0, Stata 14.1, and PROCESS macro. Results: We found that the frequency of BBFE increased in subjects with disturbed sleep (IRR = 1.87, p = .049), and the probability of non-BBFE increased in subjects showing higher infection prevention behavior (IRR = 15.05, p = .006) and a hospital safety climate (IRR = 28.46, p = .018). We also found that infection prevention behavior had mediating effects on the occupational stress-BBFE and hospital safety climate-BBFE relationships. Conclusion: Sleep disturbance is an important risk factor related to frequency of BBFE, whereas preventive factors are infection prevention behavior and hospital safety climate. We suggest individual and systemic efforts to improve sleep, occupational stress, and hospital safety climate to prevent BBFE occurrence.

• 한국응급구조학회지
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• 제26권1호
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• pp.57-70
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• 2022

Purpose: The purpose of this study was to investigate the effect of coronavirus disease-19 (COVID-19) knowledge, anxiety, and psychosocial well-being on the infection prevention behavior of college students in health care. Methods: This study is a descriptive survey research. A total of 301 college students at four health care departments in three regions were surveyed using a structured questionnaire from February 10 to February 16, 2022. The collected data were analyzed using descriptive statistics, independent t-test, and one-way ANOVA. Pearson correlation coefficients and multiple regression analyses were done using SPSS ver. 18.0. Results: Knowledge on COVID-19 was significantly dependent on a family history of chronic disease (p=.049). Anxiety was significantly dependent on test of COVID-19 (p=.040). Gender (p=.049), perceived physical and mental health status (p=.000), and chronic disease (p=.000) had significant effects on infection prevention behavior. When the level of anxiety was higher, the infection prevention behavior was also higher (p=.000) and the psychosocial well-being was improved (p=.017). Stepwise multiple regression analysis revealed that anxiety significantly improved the infection prevention behavior (𝛽=.396, p<.001) and psychosocial well-being (𝛽=-.139, p=.008), which accounts for 18.5% (F=22.444, p<.001) of the variance. Conclusion: In order to prevent infectious diseases such as COVID-19 and its spread, measures to prevent infection and improve the psychosocial well-being should also be sought.

• 한국학교보건학회지
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• 제35권3호
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• pp.75-83
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• 2022

Purpose: This study aimed to identify factors affecting COVID-19 infection prevention behaviors among teachers and administrative staff of elementary schools. Methods: A total of 204 participants, who were elementary school teachers and administrative staff, completed a pack of self-report questionnaires. The variables were COVID-19-related knowledge and COVID-19 infection prevention behaviors. The collected data were analyzed using descriptive statistics, t-test, 𝑥², Pearson's correlation coefficient, and multiple regression. Results: The participants' COVID-19-related knowledge was 3.67±0.85 and their COVID-19 prevention behaviors were 4.60±0.36. COVID-19 prevention behaviors had a positive relationship (r=.15, p=.031) with COVID-19-related knowledge. Factors affecting COVID-19 prevention behaviors were occupation (administrative staff), age, sex (male), COVID-19-related knowledge, and subjective health (good). Conclusion: It is expected that findings of the study will be used as essential data for developing strategies promoting school health. Considering the results, there is a need to create effective interventions that can increase COVID-19 infection prevention behaviors and COVID-19-related knowledge of teachers and administrative staff of elementary schools.

• Parasites, Hosts and Diseases
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• 제53권6호
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• pp.777-783
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• 2015

The nitric oxide (NO) formation and intrinsic nitrosation may be involved in the possible mechanisms of liver fluke-associated carcinogenesis. We still do not know much about the responses of inducible NO synthase (iNOS) induced by Clonorchis sinensis infection. This study was conducted to explore the pathological lesions and iNOS expressions in the liver of mice with different infection intensity levels of C. sinensis. Extensive periductal inflammatory cell infiltration, bile duct hyperplasia, and fibrosis were commonly observed during the infection. The different pathological responses in liver tissues strongly correlated with the infection intensity of C. sinensis. Massive acute spotty necrosis occurred in the liver parenchyma after a severe infection. The iNOS activity in liver tissues increased, and iNOS-expressing cells with morphological differences were observed after a moderate or severe infection. The iNOS-expressing cells in liver tissues had multiple origins.

• 문화기술의 융합
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• 제8권2호
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• pp.131-138
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• 2022

본 연구는 병원간호사의 코로나바이러스감염증-19 감염예방행위 수행도의 영향요인을 규명하기 위해 시행된 서술적 조사연구이다. 본 연구의 대상자는 대전광역시에 소재한 상급종합병원 간호사 190명이며, 자료수집은 2021년 3월에 시행하였다. 연구결과 대상자의 감염예방행위 수행도에 미치는 영향요인으로 연령(β=.25, p=.008), 근무부서(β=.15, p=.046) 및 병원안전문화(β=.17, p=.025)로 나타났으며, 모형의 전체 설명력은 8.2%로 나타났다. 따라서 상급종합병원 간호사의 감염예방행위 수행도를 높이기 위해서는 병원안전문화 형성을 증진시킬 수 있는 교육과 정책이 필요할 것으로 사료된다.

• 융합정보논문지
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• 제7권4호
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• pp.19-26
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• 2017

본 연구는 슈퍼박테리아로 불리는 메티실린 내성 황색포도알균에 대한 간호대학생의 지식과 병원실습 중 감염 예방 이행 수준과 영향요인을 파악하고자 시행하였다. 2016년 10월 14일부터 11월 30일까지 병원실습 경험이 있는 5개 대학의 간호학과 4학년 학생을 편의 추출하여 설문조사 하였고, 성실히 응답한 총 234명의 자료를 분석하였다. 연구결과, MRSA 지식은 100점으로 환산 시 52.0점이었고, MRSA 감염 예방 이행 수준은 89.41점이었다. MRSA 감염 예방 이행에 영향을 미치는 요인으로는 MRSA 교육과 실습 중 MRSA 감염 가능성에 대한 인식이 유의하였다. 그러므로 MRSA 감염 예방 이행을 증진시키기 위해서는 단순한 지식 제공보다 감염 가능성에 대한 올바른 인식을 포함한 병원실습에서 적용 가능한 교육 프로그램 개발과 교육이 필요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.4953-4960
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• 2013

Primary liver cancer is one of the most common cancers at the global level, accounting for half of all cancers in some undeveloped countries. This disease tends to occur in livers damaged through alcohol abuse, or chronic infection with hepatitis B and C, on a background of cirrhosis. Various cancer-causing substances are associated with primary liver cancer, including certain pesticides and such chemicals as vinyl chloride and arsenic. The strong association between HBV infection and liver cancer is well documented in epidemiological studies. It is generally acknowledged that the virus is involved through long term chronic infection, frequently associated with cirrhosis, suggesting a nonspecific mechanism triggered by the immune response. Chronic inflammation of liver, continuous cell death, abnormal cell growth, would increase the occurrence rate of genetic alterations and risk of disease. However, the statistics indicated that only about one fifth of HBV carries would develop HCC in lifetime, suggesting that individual variation in genome would also influence the susceptibility of HCC. The goal of this review is to highlight present level of knowledge on the role of viral infection and genetic variation in the development of liver cancer.

• 한국응용과학기술학회지
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• 제41권2호
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• pp.188-198
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• 2024

본 연구는 코로나19 대유행을 경험한 대학생의 호흡기감염 예방 이행 수준과 영향요인을 파악하고자 시행하였다. 2023년 12월 15일부터 2024년 1월 5일까지 대학생 200명을 대상으로 온라인 설문조사를 시행하였으며, 이 중 성실히 응답한 199명의 자료를 SPSS 18.0 program을 이용하여 기술통계량, t-test, ANOVA, multiple regression으로 분석하였다. 연구결과 호흡기감염 예방 이행 수준은 48점 만점 중 평균 32.95±6.05점이었다. 호흡기감염 예방 이행 수준에 차이를 보인 일반적 특성과 호흡기감염 관련 특성은 학과(t=-2.59, p=.010), 호흡기감염 예방 교육(t=1.99, p=.048), 금년 독감예방접종(t=-2.10, p=.037), 금년 코로나19 예방접종(t=3.56, p<.001), 외출 시 사람이 모여 있는 곳에서 마스크 착용(t=4.96, p<.001)이었다. 호흡기감염 예방 이행에 영향을 미치는 요인으로 학과(β=0.31, p<.001), 금년 독감예방접종(β=-0.15, p=.046), 외출 시 사람이 모여 있는 곳에서 마스크 착용(β=-0.31, p<.001)이 다중회귀분석에서 유의한 변수로 확인되었다. 결론적으로 코로나19 유행이 종식된 이후에도 호흡기감염이 지속적으로 발생하므로 호흡기감염 예방행위 이행 증진을 위한 노력이 필요하며, 대학생을 대상으로 한 호흡기감염 예방 프로그램 개발 시 본 연구에서 확인된 요인들을 기초자료로 활용할 수 있을 것으로 기대한다.