• Journal of Microbiology and Biotechnology
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• v.28 no.3
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• pp.391-396
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• 2018

It is well known that Korean red ginseng has various biological activities. However, there is little knowledge about the antiviral activity of Korean red ginseng and its ginsenosides. In this study, we addressed whether oral administration of ginsenoside-Rb2 and -Rg3 is able to protect against rotavirus (RV) infection. The protective effect of ginsenosides against RV infection was examined using an in vivo experiment model in which newborn mice (10-day-old) were inoculated perorally (p.o.) with $1.5{\times}10^6$ plaque-forming units/mouse of RV strain SA11. When various dosages of ginsenoside-Rb2 (25-250 mg/kg) were administered 3days, 2 days, or 1 day before virus challenge, treatment with this ginsenoside at the dosage of 75 mg/kg 3days before virus infection most effectively reduced RV-induced diarrhea. In addition, consecutive administration of ginsenoside-Rb2 (75 mg/kg) at 3 days, 2 days, and 1 day before virus infection was more effective than single administration on day -3. The consecutive administration of ginsenoside-Rb2 also reduced virus titers in the bowels of RV-infected mice. In an experiment to compare the protective activity between ginsenoside-Rb2 and its two hydrolytic products (20(S)- and 20(R)-ginsenoside-Rg3), 20(S)-ginsenoside-Rg3, but not 20(R)-ginsenoside-Rg3, prevented RV infection. These results suggest that ginsenoside-Rb2 and its hydrolytic product, 20(S)-ginsenoside-Rg3, are promising candidates as an antiviral agent to protect against RV infection.

• Korean Journal of Occupational Health Nursing
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• v.21 no.3
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• pp.308-316
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• 2012

Purpose: The purpose of this study was to describe the perception and practice of hospital infection control of nursing staff in long-term care hospitals by the level of supplementation of nurses. Methods: The participants were 212 nurses and nurse assistants in 13 long-term care hospitals in a metropolitan city and the data were gathered by self-reported questionnaires during August 2011 and analyzed by SPSS/WIN program. Results: The beds per a nurse were 15, and the proportion of nurses among nursing staff in long-term care hospitals was about 33%. In general, the level of infection control in practice was lower than that of perception. The highest perception and practice domain was 'Management of disinfection/contamination', and the lower level domains were 'Personal hygiene' and 'Hand washing' There were statistically significant differences in the hospital infection control of perception and practice depending on age, education, career in long-term care hospital, job position, the quantity of beds, nurse, and nurse assistant, beds per a nurse and proportion of nurses in hospitals. Conclusion: According to these results, the systematic and continual education on hospital infection control of the nursing staff in long-term hospitals should be carried out. In addition, the policy to add more nurses into long-term care hospitals must be implemented.

• Journal of Korean society of Dental Hygiene
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• v.7 no.3
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• pp.213-230
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• 2007

The purpose of this study was to examine the state of infection control provided to members of Korean Dental Hygienists Association. The subjects in this study were dental hygienists who attended a symposium on July 1. 2006. after a survey was conducted, the answer sheets from 489 participants were analyzed, and the findings of the study were as follows: 1. Possession of disinfection room was being(72.7%), and person of infection control was zero(52.9%). Number of sterilizer was one(62.2%). 2. As a repetition choice, type of sterilizer was autoclave(97.9%), UV sterilizer(67.4%) and EO gas sterilizer(21.4%). As a repetition choice, infection materials was ethanol(84.1%). 3. Water tube of unit and chair was using of sterilized water(42.9%). Sterilizing of compressed air was no(69.0%). 4. Re-using of disposal was not using(62.5%), re-using disposal was suction tip(28.2%)(repetition choice) 5. In sterilization of instruments, hand-piece was every using time(28.4%), and reamer-file, bur, mirror, pincette, explorer, hand scaler and ultrasonic scaler were high in every using time. 6. Individual protection was high of using, cleaning of hands before treatment was every treatment(87.0%). Type of soap was liquid type in dental clinic(48.2%), infection soap in dental hospital(41.2%) and solid soap in public health center(50.6%). Answered that they need regular oral health education, and 82.9% respondents answered that they need oral health technicians in school. And 87.8% respondents needed individual oral health education for the benefit of better oral health.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.4
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• pp.1184-1193
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• 2015

Monitoring for megalocytivirus infection was conducted for ten months from March to December in 2013 in 15 aquatic farms culturing, red sea bream, rock bream, rock fish and black sea bream around Tongyoung coastal area in Korea, to assess spatial and temporal variability of detection prevalence, and to explore possible links with seawater temperature. In nested-PCR targeted major capsid protein (MCP) gene, asymptomatic megalocytivirus infection was detected in the externally healthy farmed fish with a significant prevalence in range from 0 to 58.3% for ten months. Higher prevalence of megalocytivirus (46.7% - 57.1%) was observed in high water temperature season from September to November than that in other months with lower prevalence of 0.0% to 20.0%. Even though an acute infection of megalocytivirus was occurred in rock bream (positive in the first PCR) with high mortality in one of fifteen farms, there was no expansion or transmission of the disease to the rock fish and red sea bream culturing in net cage just proximal to the rock bream cage in which disease outbreaked. Nucleotide sequence analysis of the cloned MCP gene isolated asymptomatically infected rock fish revealed that the megalocytivirus in this study was clustered together with the rock bream iridovirus (RBIV) under the subgroup II of the genus megalocytivirus (Iridoviridae), which is known to be the major megalocytivirus strain in Korea. The typical histopathological signs were not found in the spleen of rock fish asymptomatically infected by megalocytivirus. Experimental infection of rock bream with the spleen homogenate of the rock fish infected asymptomatically did not induce any mortality unlike the homogenate of infected rock bream with hih mortlity. However, these results may suggest that the asymptomatic infection of megalocytivirus in other fish species can be a potential risk threatening aquaculture industries as a transmission factor of megalocytivirus to susceptible fish species, especially rock bream.

• Journal of Convergence for Information Technology
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• v.11 no.11
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• pp.85-94
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• 2021

In this study, the effects of infection control health beliefs and critical thinking tendencies of nursing students on infection control standards were investigated. This study collected and analyzed the data of 222 nursing students from the College of Nursing located in City A from June 2021 to July 2021. Data were collected according to IRB-approved contents, and the collected data were analyzed using the SPSS 26.0 Statistics Program. The infection control health beliefs and critical thinking tendencies of nursing students affect the performance of standard infection control precautions(F=16.634, p<.001), and the explanatory power of the model was 22.0%. It is necessary to develop a nursing education program to improve health beliefs and critical thinking disposition and systematic and efficient infection control education to improve the performance of standard precautions for infection control of nursing students.

• Journal of Korean society of Dental Hygiene
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• v.6 no.1
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• pp.37-48
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• 2006

Dental personnels faced risks of infection in the clinic. For infection control, recognition and practice of dental personnels are important factor. This study was performed to investigate the recognition and practice of dental hygiene for infection control and infection waste control. A stratified convenience sample of dental hygienists in dental health-care settings. The major finding of the present study are as follows: 1. The existence of education about Standard Precaution and low of infection waste storage was higher dental hospital than dental clinic. 2. The degree of practice in the storage of dental wastes was low in absorbent cotton and body tissue exclude damage waste. And the degree of practice in the disposal of dental wastes was high in all three. 3. Practice in the storage of dental waste was higher dental hospital than dental clinic. 4. At the conclusion of this investigation, systematic refresher training of infection control should be prepared by campaign an various media, Dental health care workers should be encouraged to practice those action items from training. For successful implementation of infection control in every dental health-care settings, it is highly demanded as well that development of effective safe-guard tools, stategic support, and standardized action items against infection problems.

• The Korean Journal of Emergency Medical Services
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• v.18 no.2
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• pp.21-33
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• 2014

Purpose: A descriptive study design was used to investigate infection management awareness and infection management performance for clothing management in 119 emergency medical technicians (EMTs). Method: 188 paramedics and basic EMTs completed questionnaires between March 1 and April 30, 2013 in Jeollabuk-do. Results: Participants' average score for infection control awareness was 2.69 and that for performance was 1.58, with the differences being statistically significant (t = 931.455, p = .003). Participants' general characteristics resulted in differences in infection management performance. Women (1.63) have scored higher than men (1.28), and the difference was statistically significant (t = 11.174, p = .001). Participants who had clinical experience (1.63) had higher scores than participants who did have clinical experience before (1.53) and, again, the difference was significant (t = 7.167, p = .009). Conclusion: Education program for infection management is need to be developed for more effective infection management.

• Child Health Nursing Research
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• v.13 no.4
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• pp.467-477
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• 2007

Purpose: To identify the effects of a training program on the knowledge of, attitudes towards child infection, and infection prevention behaviors in staff of daycare centers. Methods: A nonequivalent control group pretest-posttest design study was conducted with 34 staff of 6 daycare centers over 3 months. The staff in the 3 centers designated as the experimental centers received the training program weekly for 8 weeks. The program included on-site education for one and half hours and monitoring of infection prevention behaviors. Knowledge and attitudes of the staff were measured, and their infection prevention behaviors were observed and recorded by research assistants before and after the program. $X^2$-test, t-test, Fisher's exact test, and Mann-Whitney U-test with SPSS Win program were used to analyze the data. Results: The group of staff who received the training program recorded higher scores in knowledge, attitudes, and their infection prevention behaviors compared with staff in the control group. Conclusion: This finding suggests that the training program had a significant impact on knowledge, attitude, and infection prevention behaviors of staff which could prevent child infection in daycare centers. Nurses need to be involved in daycare centers for the health of the children, and they could intervene effectively in child infections by using this program.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.18 no.1
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• pp.37-45
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• 2011

Purpose: The purpose of this study was to estimate the effects of an infection control program on the Clonorchis sinensis (CS) infection ratio, CS-related knowledge and health behavior of people living near the Geum River. Method: A one-group pretest-posttest design was used with 102 participants. For 12 months the participants were provided with promotion announcements, health education, counseling, and medication. Outcome variables measured were the CS infection ratio by stool examination, CS-related knowledge and health behavior from self-report questionnaires. The pre intervention data were collected from January to February 2008 and the post intervention data during the same period in 2009. Collected data were analyzed using descriptive statistics, generalized estimating equation analysis, and paired t-test with SPSS for Windows version 15.0. Results: In the pre test 21 of the 102 participants showed infection with CS for the first time. In the post test 9 were newly infected with CS, and one was re-infected. The CS-related knowledge was significantly improved after the infection control program (p<0.05). The CS-related health behaviors did not improve. Conclusion: These results showed that an infection control program is effective in decreasing CS infection ratio and improving CS-related knowledge of people living near the river.

• Journal of Home Health Care Nursing
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• v.29 no.2
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• pp.204-215
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• 2022

Purpose: This study aimed to identify factors affecting the carbapenem-resistant enterobacteriaceae (CRE) infection control performance of nursing staff, who closely contact patients with CRE in long-term care hospitals. Methods: A cross-sectional study design was used. A total of 135 nursing staffs working in seven long-term care hospitals in the southern and northern areas of the K province in Korea were included. We measured the CRE infection control general characteristics, knowledge, perception, and performance. Results: The main factors affecting the CRE infection control performance were education, knowledge, and perception. The model explained the 60.8% total variance in CRE infection control. Conclusion: Appropriate infection control strategies should be prepared to provide high quality nursing care and prevent the spread of CRE infection in long-term care hospitals. Establishing an efficient infection control system in long-term care hospitals is necessary.