• Journal of Oral Medicine and Pain
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• v.35 no.1
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• pp.41-47
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• 2010

Burning mouth syndrome(BMS) is a chronic oral pain and a symptom complex disorder usually unaccomplished by mucosal lesion or other clinical and laboratory signs of organic disease. BMS is characterized by a spontaneous burning sensation that mainly affects middle-aged and postmenopausal women. The etiology of BMS is poorly understood even though evidence for a possible neuropathic pathogenesis. BMS cause from various local or systemic factor, including nutritional deficiencies, hormonal change, local infection, dental procedure, dry mouth, medication and systemic disease including diabetes mellitus. Many studies suggest peripheral alteration in sensory of trigeminal nerve system. BMS patients with supertaster indicates pathologies of central and peripheral nerve system induced by an alteration in the taste system at the level of chorda tympani and glossopharyngeal nerve. The author discuss our current understanding of etiology and pathogenesis of BMS that refered chronic oral pain.

• Journal of the Korean Magnetics Society
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• v.19 no.2
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• pp.52-56
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• 2009

Interlayer coupling field, coercivity, magnetoresitance ratio, and magnetic sensitivity depending on the thickness of free CoFe layer for the CoFe/Cu/CoFe/IrMn multilayer are investigated. In case of CoFe layer of $30\;{\AA}$ thickness for the CoFe(t)/Cu($25\;{\AA}$)/CoFe($60\;{\AA}$)/IrMn($80\;{\AA}$) multilayer with ferromagnet/non-magnet/ferromagnet structure induced by IrMn layer, the lowest coercivity and the highest magnetic sensitivity, which is contained soft magnetic property, are observed. On the other side, in case of CoFe layer of $90\;{\AA}$ thickness, there are the highest coercivity and the lowest magnetic sensitivity. The fabricated CoFe($30\;{\AA}$)/Cu($25\;{\AA}$)/CoFe($60\;{\AA}$)]/IrMn($80\;{\AA}$) spin valve device with $2{\times}8{\mu}m^2$ patterning size are measured by two probe method, which is selected the sensing current as the longitudinal direction and the easy axis as the transversal direction. The measuring magntoresistance ratio and magnetic sensitivity of GMR-SV device having the soft magnetic property are 3.0% and 0.3%/Oe, respectively.

• Journal of the Korean Geographical Society
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• v.49 no.2
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• pp.200-220
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• 2014

This study reexamines the old concept and reviews prevalent statements on Cenozoic vertical motions of the peninsula that have been uncritically repeated in our academia. The contents of this paper are redefinition of the notion, tilted flexure or warping, and a suggestion for a new time set and properties of the deformation, followed by a new model on its influencing factors and processes. In conclusion, the Cenozoic vertical motion of the Korean peninsula can be reified further with an epeirogenic movement of uplift in the east side-subsidence in the west side of the peninsula since the Neogene (23 Ma). However, the regional boundary for areas of uplift and subsidence is not likely in the Korean peninsula but broader farther to East China and the southern part of Russia. It can be best understood that mantle convection produced by subducting activities in the Western Pacific Subduction Zone causes the uplift and subsidence of earth surface around NE Asia. In addition, faultings in the upper lithosphere induced by in-situ plate boundary stresses accelerate regional uplift in the peninsula since the Quaternary. Controversies that are still standing such as current uplift movements along the western coast of the peninsula during the late Quaternary could be precisely discussed with future research providing detailed information on it.

• Convergence Security Journal
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• v.16 no.6_2
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• pp.61-71
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• 2016

In this study, Private investigation in South Korea, while gone through so far of politics, the process of social change, a positive feature, without evolve, insufficient growth and security services of the business burden of national judicial institutions, detective industry international of the negative vicious circle, such as the acquisition of drop and expedient information of competitiveness is continuously induced it is a reality. It is, therefore, to the proposal, such as the following. First, it must be able to use the term "detective". Secondly, in order to verify the validity of this system, after introducing the first private sphere, in accordance with the stepwise its necessity, it is desirable to extend the operational range of the public area. Third, to have a country of qualification to private research workers, will be managed directly from the country is ideal. Fourth, we must also seek plan to specialize the designated educational institution as a commissioned education institution to institution with a faculty and facilities that are specialized. Fifth, the National Police Agency must manage and supervise the private investigation business. Sixth, the legislative form to amend the current security law, as a kind of private security, must be introduced by adding a private trillion business. Therefore, in order to complement the limitation of such studies, additional subsequent research has if it is not carried out.

• Journal of the Korean earth science society
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• v.36 no.6
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• pp.520-532
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• 2015

In order to understand the Holocene sea level changes in the eastern Yellow Sea, the west coast of Korea, and to compare the rates of sea level rise in each period of time, the geological proxy records for pre-instrumental era and measurement data for the present day were combined and analysed. The sea level in the Yellow Sea rose fast with a rate of about 10 mm/yr during the early Holocene, and decelerated down to 1 mm/yr since the mid to late Holocene. The rising rates of sea level in the 20th century were slightly higher than those in the late Holocene. The present-day rates of sea level rise, known as the 'rapid' rise, are in fact much lower or similar, compared to the early to mid Holocene sea levels in the study area. Recent tide-gauge data show that sea level rise in the eastern Yellow Sea has been accelerating toward the 21st century. These rising trends coincide well with global rising patterns in sea level. Additionally, the present-day rising trends of sea level in this study are correlated with increased rates of carbon dioxide concentrations and sea surface temperatures, further indicating a signal to global warming associated with the human effect. Thus, the sea level changes induced by current global warming observed in the eastern Yellow Sea and world's oceans can be considered as 'Anthropocene' sea level changes. The changes in sea level are based on instrumental measurements such as tide-gauges and satellite altimetry, meaning the instrumental era. The Holocene changes in sea level can thus be reconstructed from geological proxy records, whereas the Anthropocene sea-level changes can be solely based on instrumental measurements.

• Tuberculosis and Respiratory Diseases
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• v.57 no.2
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• pp.125-131
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• 2004

Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate BCG vaccine is urgently needed. We constructed three recombinant Mycobacterium bovis BCG (rBCG) strains over-expressing antigen (Ag) 85A, Ag85B, or both of M. tuberculosis using their own promoter and secretory sequence, or hsp60 promoter. SDS-PAGE analysis of rBCG proteins showed overexpression of Ag85A and Ag85B proteins in higher level than of those in their parental strain of BCG. In addition, rBCG(rBCG/B.FA) over-expressing Ag85A and Ag85B induced strong IFN-${\gamma}$ production in splenocytes. However, there was no significant difference in protective efficacy between rBCG and their parental BCG strain. In this study, therefore, rBCG over-expressing Ag85A, Ag85B, or both failed to show enhanced protection against M. tuberculosis infection in a mouse model.

• Carbon letters
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• v.28
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• pp.31-37
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• 2018

This paper examines a simple one-step and catalyst-free method for synthesizing carbon nanoparticles from aliphatic alcohols and n-hexane with linear molecule formations by using a stable solution plasma process with a bipolar pulse and an external resistor. When the external resistor is adopted, it is observed that the current spikes are dramatically decreased, which induced production of a more stable discharge. Six aliphatic linear alcohols (methanol-hexanol) containing carbon with oxygen sources are studied as possible precursors for the massive production of carbon nanoparticles. Additional study is also carried out with the use of n-hexane containing many carbons without an oxygen source in order to enhance the formation of carbon nanoparticles and to eliminate unwanted oxygen effects. The obtained carbon nanoparticles are characterized with field emission-scanning electron microscopy, energy dispersive X-ray spectroscopy, and Raman spectroscopy. The results show that with increasing carbon ratios in alcohol content, the synthesis rate of carbon nanoparticles is increased, whereas the size of the carbon nanoparticles is decreased. Moreover, the degree of graphitization of the carbon nanoparticles synthesized from 1-hexanol and n-hexane with a high carbon (C)/oxygen (O) ratio and low or no oxygen is observed to be greater than that of the carbon nanoparticles synthesized from the corresponding materials with a low C/O ratio.

• IMMUNE NETWORK
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• v.3 no.2
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• pp.136-144
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• 2003

Oral administration of antigen has long been considered as a promising alternative for the treatment of chronic autoimmune diseases including rheumatoid arthritis (RA), and oral application of type II collagen (CII) has been proven to improve pathogenic symptoms in RA patients without problematic side effects. To further current understandings about the immune suppression mechanisms mediated by orally administered antigens, we examined the changes in IgG subtypes, T-cell proliferative response, and proportion of interleukin (IL)-10 producing Th subsets in a time course study of collagen induced arthritis (CIA) animal models. We found that joint inflammation in CIA mouse peaked at 5 weeks after first immunization with CII, which was significantly subdued in mice pre-treated by repeated oral administration of CII. Orally tolerized mice also showed increase in their serum level of IgG1, while the level of IgG2a was decreased. T-cell proliferation upon CII stimulation was also suppressed in lymph nodes of mice given oral administration of CII compared to non-tolerized controls. When cultured in vitro in the presence of CII, T-cells isolated from orally tolerized mice presented higher proportion of $CD4^+IL-10^+$ subsets compared to non-tolerized controls. Interestingly, such increase in IL-10 producing cells were obvious first in Peyer's patch, then by 5 weeks after immunization, in mesenteric lymph node and spleen instead. This result indicates that a particular subset of T-cells with immune suppressive functions might have migrated from the original contact site with CII to inflamed joints via peripheral blood after 5 weeks post immunization.

• Journal of the Korean Geosynthetics Society
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• v.15 no.1
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• pp.21-35
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• 2016

It is a current trend that the concrete track is applied for high speed railway. In the case of the railway embankment constructed on soft ground, the damage to concrete track which is sensitive to settlement such as distortion and deflection could be caused by very small amount of long term settlement. Pile Supported Embankment method can be considered as the effective method to control the residual settlement of the railway embankment on soft ground. The Geosynthetics is used inside of the embankment to maximize the arching effect transmitting the load of the embankment to the top of the piles. But, PHC piles that are generally used for bridge structures are also applied as the pile supporting the load of embankment concentrated by the effect of the Geosynthetics. That is very low efficiency in respect of pile material. So, in this study, the cast in place concrete pile was selected as the most suitable pile type for supporting the embankment by a case study and the optimum mixing condition of concrete using a by-product of industry was induced by performing the mixing designs and the compressive strength designs. And it is shown that the cast in place pile with the optimum mixing condition using the by-product of industry is 2.8 times more efficient than the PHC pile for the purpose of Pile Supported Embankment by the finite element analysis method.

• Proceedings of the Korean Geotechical Society Conference
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• 2006.03a
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• pp.86-95
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• 2006

Brillouin backscatter is a type of reflection that occurs when light is shone into an optical fibre. Brillouin reflections are very sensitive to changes in the fibre arising from external effects, such as temperature, strain and pressure. We report here several case studies on the measurement of strain using Brillouin reflections. A mechanical bending test of an I beam, deployed with both fiber optic sensors and conventional strain gauge rosettes, was performed with the aim of evaluating: (1) the capability and technical limit of the DTSS technology for strain profile sensing; (2) the reliability of strain measurement using fiber optic sensor. The average values of strains obtained from both DTSS and strain gauges (corresponding to the deflection of I beam) showed a linear relationship and an excellent one-to-one match. A practical application of DTSS technology as an early warning system for land sliding or subsidence was examined through a field test at a hillside. Extremely strong, lightweight, rugged, survivable tight-buffered cables, designed for optimal strain transfer to the fibre, were used and clamped on the subsurface at a depth of about 50cm. It was proved that DTSS measurements could detect the exact position and the progress of strain changes induced by land sliding and subsidence. We also carried out the first ever distributed dynamic strain measurement (10Hz) on the Korean Train eXpress(KTX) railway track in Daejeon, Korea. The aim was to analyse the integrity of a section of track that had recently been repaired. The Sensornet DTSS was used to monitor this 85m section of track while a KTX train passed over. In the repaired section the strain increases to levels of 90 microstrain, whereas in the section of regular track the strain is in the region of 30-50 microstrain. The results were excellent since they demonstrate that the DTSS is able to measure small, dynamic changes in strain in rails during normal operating conditions. The current 10km range of the DTSS creates a potential to monitor the integrity of large lengths of track, and especially higher risk sections such as bridges, repaired track and areas at risk of subsidence.