• Title/Summary/Keyword: Increased efficacy

검색결과 2,131건 처리시간 0.026초

전도산(顚倒散)의 추출용매에 따른 항염 및 항산화 비교 연구 (The Comparative Study of Anti-inflammation and Anti-oxidation in Accodance with Extraction Solvents of Jeondo-san)

  • 서형식
    • 한방안이비인후피부과학회지
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    • 제23권2호
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    • pp.69-80
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    • 2010
  • Objective : The purpose of this study was to compare anti-Inflammation and anti-oxidation of Jeondo-San(JDS) extracted with two kinds of solvents, ethanol and water. Methods : Two kinds of JDS extractions were prepared 20, 50, $100\;{\mu}g/mg$. The Cytotoxicity was measured by MTT assay in Raw 264.7 cell. The anti-inflammation effects were measured by inhibitory efficacy on $PGE_2$, NO, TNF-$\alpha$, COX-2 and iNOS in Raw 264.7 cell. The anti-oxidation effects were measured by ROS inhibitory efficacy, intracellular GSH synthesis and DPPH Radical scavenging in HaCaT cell. Results : 1. All of JDS extraction groups had no cytotoxicity in Raw 264.7 cell. 2. All of JDS extraction groups showed significantly inhibitory effect on production of $PGE_2$. Inhibitory efficacy increased in accodance with concentration. 3. All of JDS extraction groups showed significantly inhibitory effect on production of NO. Inhibitory efficacy increased in accodance with concentration. 4. All of JDS extraction groups did not show significantly inhibitory effect on production of TNF-$\alpha$. 5. $100\;{\mu}g/ml$ JDS extracted with ethanol and $50\;{\mu}g/ml$, $100\;{\mu}g/ml$ JDS extracted with water showed inhibitory effect on iNOS expression. 6. All of JDS extraction groups showed significantly inhibitory effect on production of ROS. Inhibitory efficacy increased in accodance with concentration. Ethanol extractions were better than water extractions. 7. $100\;{\mu}g/ml$ JDS extracted with ethanol only produced GSH of $32{\pm}5.2%$. 8. All of JDS extraction groups showed significantly scavenging effect of DPPH radicals. Inhibitory efficacy increased in accodance with concentration. Ethanol extractions were better than water extractions. Conclusion : Two kinds of JDS extractions have not cytotoxicity and inhibit production of NO. JDS extracted with water was effective in anti-inflammation, JDS extracted with ethanol was effective in anti-oxidation.

온신환(溫腎丸)이 백서(白鼠)의 배란(排卵)에 미치는 영향(影響) (Effects of Onsinhwan on the ovulation in rats)

  • 위석;민경헌;조한백;유심근;김덕님
    • 대한한방부인과학회지
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    • 제15권4호
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    • pp.32-44
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    • 2002
  • Onsinhwan(OSH : 溫腎丸) is used in female infertility, especially due to lack of kidney yang or Sinyanghe(腎陽虛). An attempt was made to evaluate the influences of OSH on the serum concentrations of FSH and LH, Estrogen, Progesterone and the histological and optical changes of ovary, ovary weight of rats. The results of the study were as follows : 1. Blood FSH level increased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. 2. Blood LH level decreased in experimental group as compared with control group on 14th day, which showed no efficacy. 3. Blood Estrogen level increased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. 4. Blood Progesterone level decreased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. 5. In histological observations of ovary, ovulation increased in experimental group as compared control group on 7th and on 14th day, which showed no efficacy. 6. In optically observations of ovary, size and weight of ovary increased in experimental group on 7th day and on 14th day, which showed no efficacy. According to these results, OSH did not influence on the ovulation of ovary in rats.

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스트레칭체조에 대한 교육이 여성근로자의 근골격계질환 예방을 위한 자기효능감, 건강신념 및 실천의지에 미치는 효과 (The Effects of Stretching Exercise Education on Female Workers' Self-efficacy, Health Belief and Practical Intention for Preventing Musculoskeletal Diseases)

  • 기미영;정혜선;김영임
    • 한국직업건강간호학회지
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    • 제13권2호
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    • pp.130-139
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    • 2004
  • Purpose: The purpose of this study is to examine the effect of stretching exercise education on female workers' behavior for preventing musculoskeletal diseases. Method: This study educated occupational health nurses working in Seoul and Kyunggi area for stretching exercise methods and then had them educate female workers in each workplace for the stretching exercise methods. The subjects of this study were 205 female workers and the research period was from June to October 2003. Results: The female workers' self-efficacy on stretching exercise increased significantly. The female workers' perceived susceptibility on stretching exercise increased significantly. As for change in practical intention on preventive behavior for musculoskeletal diseases, those who replied to have a plan to exercise regularly and to want to participate in stretching exercise class increased significantly. According to whether to have subjective musculoskeletal symptoms or not, self-efficacy increased significantly after education in both workers with such symptoms and those without, and perceived susceptibility and cue to action increased significantly after education in workers without such symptoms. Conclusion: It is necessary to develop programs to increase self-efficacy and health belief and to apply them to female workers to prevent musculoskeletal diseases. In addition, it is necessary to provide repeated education for female workers' steady practice of preventive behavior.

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브레인스피닝 프로그램이 소아청소년의 인지기능, 신체조성, 건강관련체력에 미치는 영향 (Effects of Brain Spinning Program on Cognitive Function, Body Composition, and Health Related Fitness of Children and Adolescents)

  • 김준혁;송욱;송인수;김현준;임병걸;허정윤
    • 대한통합의학회지
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    • 제12권1호
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    • pp.83-96
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    • 2024
  • Purpose : This study was conducted to determine the effects of a brain spinning program on cognitive function, body composition, health related fitness and physical self-efficacy of children and adolescents. Methods : This study, 34 children and adolescents were selected and divided into two groups : the exercise group (n=16), which received a brain spinning program and the control group (n=16), which did not receive any exercise program. The program was conducted for 30 minutes three times a week for 4 weeks, and the cognitive function, body composition, health related fitness and physical self-efficacy were measured both before and after the program. Results : The exercise group, which received a brain spinning program showed a significant increase in short-term memory (p<.05) and working memory (p<.01), and muscle mass increased significantly only in the exercise group (p<.05). In addition, left grip strength increased in the exercise group (p<.01), and the maximum oxygen intake decreased significantly only in the control group (p<.05), and Sit-forward bend increased significantly only in the exercise group (p<.01). Physical self-efficacy significantly increased only in the exercise group (p<.05). Conclusion : In summary, short-term memory, cognitive efficiency, working memory, muscle mass, left grip strength, maximum oxygen intake, and left forward bending in children and adolescents significantly increased after the 4-week brain spinning program. However, the control group that was not provided with the 4-week brain spinning program showed a significant increase in body weight and a significant decrease in maximum oxygen intake. In conclusion, the 4-week brain spinning program has positive effects on short-term memory, cognitive function, muscle mass, muscle strength, cardiorespiratory endurance, flexibility, and physical self-efficacy.

자기효능증진 운동프로그램이 신장이식 환자의 체중, 체지방율, 운동시간 및 심폐기능에 미치는 효과 (The Effects of the Self Efficacy Promotion and Exercise Program on the weight, body fat rate, exercise time and cardiopulmonary function of kidney transplant recipients)

  • 안재현;김남초
    • 성인간호학회지
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    • 제12권3호
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    • pp.452-462
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    • 2000
  • The purpose of this study is to develop and evaluate the Self Efficacy Promotion and Exercise Program to prevent of obesity and cardiovascular diseases for the kidney transplant recipients. The subjects were selected randomly among the patients who underwent kidney transplantations at one major transplantation hospital in Seoul, Korea. This study ws carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids therapy and did not take any physical exercise regularly. The subjects received the self efficacy promotion and exercise program for 12 weeks which contained self efficacy promotion education and exercise program. The weight, body fat rate, exercise time and cardiopulmonary function were evaluated before the experiment and after the experiment. The results were as follows: 1. After the experiment, the weight was significantly decreased than that of before the experiment(p=.0001). 2. After the experiment, the body fat rate was significantly decreased than that of before the experiment(p=.0010). 3. After the experiment, the exercise time was significantly increased than that of before the experiment(p=.0002). 4. After the experiment, the absolute VO2 was significantly increased than that of before the experiment(p=.0008). 5. After the experiment, the relative VO2 was significantly increased than that of before the experiment(p=.0002). This study showed that the self efficacy promotion and exercise program was effective. So it would be expected that this self efficacy promotion and exercise program could be applied as an effective independent nursing intervention widely in prevention of obesity and cardiovascular diseases for kidney transplant recipients.

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강원지역 초등학생의 영양지식, 식생활태도, 식이자기효능감과의 관련성 (Relationships among Eating Behavior, Dietary Self Efficacy and Nutrition Knowledge of Elementary School Students in Gangwon Province)

  • 원향례
    • 한국지역사회생활과학회지
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    • 제19권1호
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    • pp.11-19
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    • 2008
  • This study was made to provide basic materials required to develop the program for desirable change of eating behavior which might be regarded as the aim of nutrition education. In this study, the relationship between the factors known to be affecting eating behavior like nutrition knowledge and dietary self efficacy was examined with high grade elementary students in Gangwon Province. The results are as follows; First, positive relationship was observed with significant difference(p<0.001) in the relationships between eating behavior and dietary self efficacy(r=0.465), between nutrition knowledge level and eating behavior(r=0.216) and between nutrition knowledge level and dietary self efficacy(r=0.312). Second, the ratio explaining the effect of dietary self efficacy and nutrition knowledge on eating behavior was 22.3%, and it affected in the order of significance level such that dietary self efficacy(p<0.001) and nutrition knowledge level(p<0.05). Third, the level of desirable eating behavior was consistent with the level of nutrition knowledge. And the scores of nutrition knowledge were $28.97{\pm}4.66$ for 'poor' group, $30.01{\pm}3.85$ for 'normal' group, $31.13{\pm}3.94$ for 'good' group and $31.75{\pm}4.10$ for 'excellent' group. When the scores of eating behavior was considered in accordance with the level of nutrition knowledge, there was difference between the groups with poor and normal scores and the groups with good and excellent scores(p<0.001), however, there was no difference between poor and normal group, and between good and excellent group. Fourth, it was found that dietary self efficacy affected the eating behavior level by level. The eating behavior score was $23.82{\pm}5.25$ for the poor dietary self efficacy group, $26.88{\pm}4.00$ for the normal group, $30.27{\pm}3.66$ for the good group and $32.81{\pm}3.79$ for the excellent group. It showed that as the degree of dietary self efficacy increased the degree of eating behavior increased in all four groups (p<0.001).

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걷기지도자 교육과정이 걷기운동지식과 자기효능감에 미치는 효과 (The Effects of a Walking Leader Program on Walking Knowledge and Self-efficacy)

  • 이창현;김영임;김숙영
    • 지역사회간호학회지
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    • 제21권2호
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    • pp.178-187
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    • 2010
  • Purpose: The purpose of this study was to analyze the effects of a walking leader program on changes in walking knowledge and self-efficacy. Methods: The subjects were 276 participants who participated in the nationwide walking leader program 9 times from May to September in 2008. Data were collected before and after the program by an organized questionnaire. Results: 1) Knowledge related to walking exercise increased significantly to 4.14 point from 2.90 point after the program (t=-20.70, p<.001). 2) Self-efficacy related to walking exercise increased significantly to 4.08 point from 3.40 point after the program (t=13.93, p<.001). 3) Significant factors that affected knowledge and self efficacy before the program were regular exercise and subjective health status. The history of chronic disease and smoking were significantly affecting factors to knowledge and self-efficacy after the program. Conclusion: The walking leader program promoted the participants' walking knowledge and selfefficacy. It is necessary to develop more specific programs tailored to socio-demographic characteristics of participants and to make efforts to increase participants with active public information.

청소년의 아침식사와 운동 행동변화단계에 따른 영양지식, 식이자기효능감과 식습관 (Nutrition Knowledge, Dietary Self-Efficacy and Eating Habits According to Student's Stage of Regular Breakfast or Exercise)

  • 최미영;김혜영
    • 대한지역사회영양학회지
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    • 제13권5호
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    • pp.653-662
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    • 2008
  • This study has been performed to analyze nutrition knowledge, dietary self-efficacy and eating habits of the elementary- and middle- school students (n = 342) according to student's stage of regular breakfast or exercise. Middle school students had higher nutrition knowledge than primary school students. Total dietary self-efficacy and dietary habit scores were not different by school year and gender. Nutrition knowledge, dietary self-efficacy and dietary habit scores were positively correlated each other. By the stage of regular breakfast, the pre-contemplation stage comprised 13.6%, contemplation 2.1%, preparation 15.7%, action 11.5% and maintenance stage 59.1%. By the stage of regular exercise, the pre-contemplation stage comprised 20.9%, contemplation 7.3%, preparation 45.6%, action 9.8% and maintenance stage 16.4%. According to the stage of change, movement from the pre-contemplation and contemplation to upper stage increased the dietary self-efficacy score. Dietary habit score increased significantly across the five stages of changes. The results of this study indicate differences in stages of changes in breakfast intake and regular exercise and indicate the need for taking these phases of change into account in nutrition education.

일부 고등학생의 체간 안정화 훈련이 의식적 자세조절 효능감, 신체적 자기개념, 지각된 스트레스에 미치는 영향 (The Effects of Trunk Stabilization Training on the Self Posture Control Efficacy, Physical Self-Description and Perception Stress in High School Students)

  • 이대로;공선웅;정연우
    • 대한정형도수물리치료학회지
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    • 제19권1호
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    • pp.33-39
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    • 2013
  • Background: The purpose of this study was to find out the effect of trunk stabilization training on the self posture control efficacy, physical self-description and perception stress in high school students. Methods: 92 voluntary students (73 females, 19 males) participated in this study. They received trunk stabilization training for 40 minutes per day and a time per week during 6 weeks period. Trunk stabilization training was an approach of education in proper posture and coordination of movement. In the evaluation, the self posture control efficacy scale (SPCES) was used to measure the posture control efficacy, the physical self-description questionnaire (PSDQ) was used to measure the physical self description and the perception stress scale (PSS) was used to measure the stress. All measurement of each subject were measured before and after stabilization training. Results: The SPCES were significantly different before and after (p<.05). The PSDQ and PSS were no significantly different before and after (p>.05) but the means were increased slightly. Conclusion: Conclusionally these results suggest that the trunk stabilization training increased the self posture control efficacy and would give help to control Students themselves.

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건강증진 교육프로그램이 여대생의 성, 음주, 흡연에 대한 지식, 태도, 효능감에 미치는 영향 (Effects of Health Promotion Education Program on the Knowledge, Attitude, and Self Efficacy in Sexuality, Drinking, and Smoking Among College Women)

  • 허혜경;김기연;박소미;신윤희
    • 보건교육건강증진학회지
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    • 제20권2호
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    • pp.19-33
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    • 2003
  • A simulated control group pretest-posttest design was used to investigate the effects of a health promotion education program on knowledge, attitude, and self-efficacy in sexuality, drinking, and smoking among college women. The subjects included 17 women in the experimental group, and twenty in the control group. This program was carried out for a total of four sessions, two hours per session once a week. The results were as follows; 1) Knowledge on sexuality, drinking, and smoking increased significantly in the experimental group compared to the control group (U=66.50, p=.001 ; U=23.50, p=.000; U=29.50, p=.000). 2) For attitude, only the attitude to drinking showed a significant difference between the two groups (U=76.00, p=.004). 3) For self-efficacy, only self-efficacy on drinking showed a significant difference between the two groups (U=55.00, p=.000). In conclusion, the health promotion program for college women increased their knowledge on sexuality, drinking, and smoking. This program affected their attitude and self-efficacy towards moderation in drinking. A even more appropriate education program on sexuality, drinking, and smoking for college women could be developed using this program by addressing the limitations in this study and repeating the study with a more varied sample.