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Reaction Intermediate of Organic Sulfur Compund Ⅱ. Nucleophilic Substitution Reaction of Disulfonyl Chloride Compounds

  • Dae-Dong Sung;Dae-Il Jung;Kyu-Chul Kim;Yang-Hee Kim;Soo-Dong Yoh
    • Bulletin of the Korean Chemical Society
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    • v.11 no.1
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    • pp.65-69
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    • 1990
  • The nucleophilic substitution reactions of naphthalene-1,5-disulfonyl chloride and 4-fluorosulfonylbenzenesulfonyl chloride with p-substituted anilines and methyl substituted pyridines in methanol-acetonitrile mixtures and hydrolyses of those disulfonyl halides have been studied by means of conductometric and polarographic methods. A large difference in the selective parameter, ${\rho}_N$ between mono-sulfonyl chloride and disulfonyl halide can be taken as an evidence that the second $SO_2Cl$ grolup of naphthalene-1,5-disulfonyl chloride also takes part in the reaction in contrast to sulfonyl fluoride in 4-fluorosulfonylbenzenesulfonyl chloride, which only acts as a substituent in the nucleophilic substitution reaction.

Intussusception and Jejunal Atresia Caused by an Ectopic Pancreas in a Newborn

  • Kim, Han-Sol;Lee, Sun-Young;Han, Song-Hee;Nam, So-Hyun;Jo, Chae-Ku;Kim, Myo-Jing
    • Neonatal Medicine
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    • v.28 no.2
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    • pp.72-76
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    • 2021
  • Ectopic pancreas is defined as an abnormally located pancreatic tissue not sufficiently connected with the normal pancreas, which rarely occurs in neonates. To our knowledge, only a few cases of ectopic pancreas have been reported in newborns in South Korea. We report a case of ectopic pancreas as the cause of intussusception and jejunal atresia in a newborn. This clinical association is extremely rare, and this is the first report in South Korea.

A bibliographical study of acupuncture and moxibustion therapy in the rhinological section(in the Oehyeong chapter) of Dong Ui Bo Gam (동의보감(東醫寶鑑) 비문(鼻門)의 침구법(鍼灸法)에 관한 소고(小考))

  • Lee, Jong-Wook;Lee, Joon-Moo
    • Korean Journal of Acupuncture
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    • v.25 no.1
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    • pp.61-71
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    • 2008
  • Objectives : The aim of this study was to show the rationale of point-selection on the methods of acupuncture and moxibustion in the Rhinological section(in the Oehyeong chapter) of the Dong Ui BO Gam. Methods : First, We summarized the cause of each disease in the Rhinological section(in the Oehyeong chapter) of the Dong Ui BO Gam. Then, We explained the rationale of acupoint-selection referring to the cause of disease, physiology of the Oriental medicine, other uses of each acupoints in the Dong Ui BO Gam, character of each acupoints, flow of meridian pathways and specific acupoints etc. Results and Conclusions : Total 15 acupoints were used in the Rhinological section(in the Oehyeong chapter) of the Dong Ui BO Gam. Most of acupoints were specific acupoints. But, some rationale of acupoint-selection were explained by the cause of disease, physiology of the Oriental medicine, other uses of each acupoints in the Dong Ui BO Gam, flow of meridian pathways etc.

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Study on the methods of acupuncture and moxibustion in the ear section (in the Oehyeong Chapter) of the Dong Ui Bo Gam (동의보감(東醫寶鑑) 이문(耳門)의 침구법(鍼灸法)에 관한 소고(小考))

  • Yang, Seung-Hui;Lee, Joon-Moo
    • Korean Journal of Acupuncture
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    • v.25 no.1
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    • pp.73-83
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    • 2008
  • Objectives : The aim of this study was to show the rationale of point-selection on the methods of acupuncture and moxibustion in the Ear Section (in the Oehyeong Chapter) of the Dong Ui Bo Gam. Methods : First, We summarized the cause of each disease in the Ear Section (in the Oehyeong Chapter) of the Dong Ui Bo Gam. Then, We explained the rationale of acupoint-selection referring to the cause of disease, physiology of the Oriental medicine, other uses of each acupoints in the Dong Ui Bo Gam, character of each acupuncture points, flow of meridian pathways and specific acupoints etc. Results and Conclusions : Total 23 acupoints were used in the Ear Section (in the Oehyeong Chapter) of the Dong Ui Bo Gam. Most of acupoints were specific acupuncture points. But, some rationale of acupoint-selection were explained by the cause of disease, physiology of the Oriental medicine, other uses of each acupoints in the Dong Ui Bo Gam, flow of meridian pathways etc.

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Bacteremia caused by Leuconostoc species : 6-case series

  • Oh, Ki Jong;Jung, Dong Sik;Ko, Kwan Soo;Lee, Ho Jin;Park, Jun Yong;Lee, Hyuck
    • Kosin Medical Journal
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    • v.33 no.3
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    • pp.422-430
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    • 2018
  • Leuconostoc species are Gram-positive coccobacilli and are used in dairy products and are intrinsically resistant to vancomycin. Leuconostoc infections are rare in humans, usually occurring in immune-compromised patients. We describe 6 patients with Leuconostoc bacteremia at Dong-A university hospital between 1990 and 2015. One isolate (L. lactis) was identified to species level using 16S rRNA gene sequencing analysis. All patients had underlying diseases and 5 patients underwent procedures that interrupted the normal integumentary defense. Four patients died within 30 days after being identified as carrying Leuconostoc species.

PROTECTIVE EFFECT OF DA-3711, A NEW ANTIWRINKLE AGENT, AGAINST UVB-INDUCED SKIN DAMAGE IN HAIRLESS MICE MODEL

  • Kim, J. M.;Y. S. Sohn;K. K. Kang;Lee, E. D.;Lee, M. Y.;B. O. Ahn;Lee, J. H.;J. W. Kwon;Kim, W. B.
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.698-699
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    • 2003
  • DA-3711 is a novel, anti wrinkle agent containing growth factors derived from human skin culture. In this study, effect of topical application of DA-3711 on chronic ultraviolet B (UVB)-induced skin damage was evaluated in hairless mice model. Exposure to UVB for 8 weeks induced apparent wrinkles on the back skin of the mice. The dorsal surfaces were exposed to UVB for a further 8 weeks, during which the surfaces where treated daily by topically application of a lotion containing either 35% or 70% of DA-3711. For comparison, lotion base, lotion base containing Cylasphere Retinol(equation omitted) (2500 I.U., Coletica) and NouriCe $l^{(R)}$ (Biozhem) were applied topically once a day for 8 weeks.(omitted))

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A Case Report of Abdominal Pain after subdural hemorrhage (경막하출혈 이후 발생한 복통환자 치험 1례)

  • Ahn, Hyo-Jin;Ryu, Ho-Sun;Ko, In-Sung;Lee, Su-Bin;Yu, Sung-Wun;Lee, Yu-jin;Park, Se-Jin;Park, Sang-Dong
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.13 no.1
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    • pp.95-101
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    • 2012
  • The purpose of this report is to investigate the clinical application of Korean Traditional treatment to abdominal pain patient after subdural hemorrhage occurred. The main herb medicine used in this study is Ondam-tang (wenda-tang) which is frequently used in psychiatric disorders. Also, acupuncture, moxibustion and physical rehabilitation treatment were practiced. After taking an Ondam-tang (wendan-tang), the clinical symptoms of the patient were improved.

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